ES2172179T3 - Composiciones farmaceuticas de liberacion controlada que contienen tiagabina. - Google Patents
Composiciones farmaceuticas de liberacion controlada que contienen tiagabina.Info
- Publication number
- ES2172179T3 ES2172179T3 ES98937738T ES98937738T ES2172179T3 ES 2172179 T3 ES2172179 T3 ES 2172179T3 ES 98937738 T ES98937738 T ES 98937738T ES 98937738 T ES98937738 T ES 98937738T ES 2172179 T3 ES2172179 T3 ES 2172179T3
- Authority
- ES
- Spain
- Prior art keywords
- hours
- controlled release
- tiagabine
- thiagabine
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000036470 plasma concentration Effects 0.000 abstract 3
- PBJUNZJWGZTSKL-MRXNPFEDSA-N tiagabine Chemical compound C1=CSC(C(=CCCN2C[C@@H](CCC2)C(O)=O)C2=C(C=CS2)C)=C1C PBJUNZJWGZTSKL-MRXNPFEDSA-N 0.000 abstract 3
- 229960001918 tiagabine Drugs 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
- 239000008183 oral pharmaceutical preparation Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5443297P | 1997-08-01 | 1997-08-01 | |
| IE19970588A IE970588A1 (en) | 1997-08-01 | 1997-08-08 | Controlled release pharmaceutical compositions containing tiagabine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2172179T3 true ES2172179T3 (es) | 2002-09-16 |
Family
ID=26320083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98937738T Expired - Lifetime ES2172179T3 (es) | 1997-08-01 | 1998-07-30 | Composiciones farmaceuticas de liberacion controlada que contienen tiagabina. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0991409B1 (enExample) |
| JP (1) | JP2001511450A (enExample) |
| AT (1) | ATE212550T1 (enExample) |
| AU (1) | AU8643698A (enExample) |
| CA (1) | CA2299464C (enExample) |
| DE (1) | DE69803670T2 (enExample) |
| DK (1) | DK0991409T3 (enExample) |
| ES (1) | ES2172179T3 (enExample) |
| PT (1) | PT991409E (enExample) |
| WO (1) | WO1999006045A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA99407B (en) * | 1998-01-22 | 1999-07-20 | Abbott Lab | Extended release tiagabine formulations with reduced side-effects. |
| AU2002325404B2 (en) * | 1998-01-22 | 2006-02-02 | Abbott Laboratories | Extended Release Tiagabine Formulations with Reduced Side-effects |
| RU2220715C2 (ru) * | 1999-08-04 | 2004-01-10 | Яманоути Фармасьютикал Ко., Лтд. | Стабильная пероральная, образующая гидрогель, фармацевтическая композиция, способ ее получения, способ предотвращения изменений высвобождения лекарственного средства, способ увеличения физической стабильности пероральной композиции |
| KR100510270B1 (ko) * | 2002-11-29 | 2005-08-26 | 센츄론(주) | 펠렛타이저를 이용한 서방성 제제의 제조방법 |
| US7442387B2 (en) * | 2003-03-06 | 2008-10-28 | Astellas Pharma Inc. | Pharmaceutical composition for controlled release of active substances and manufacturing method thereof |
| EP1603540A2 (en) * | 2003-03-14 | 2005-12-14 | Nirmal Mulye | A process for preparing sustained release tablets |
| US20130143867A1 (en) | 2011-12-02 | 2013-06-06 | Sychroneuron Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
| EP3878445A3 (en) | 2013-06-05 | 2021-10-27 | Synchroneuron Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK288385D0 (da) * | 1985-06-26 | 1985-06-26 | Novo Industri As | Aminosyrederivater |
| ZA953078B (en) * | 1994-04-28 | 1996-01-05 | Alza Corp | Effective therapy for epilepsies |
| US5750140A (en) * | 1994-05-20 | 1998-05-12 | Novo Nordisk A/S | Transdermal delivery of tiagabine |
| PT830132E (pt) * | 1995-05-05 | 2002-07-31 | Novo Nordisk As | Composicao farmaceutica contendo hidrocloruro de tiagabina como ingrediente activo e seu processo de preparacao |
| DE19525598C2 (de) * | 1995-07-13 | 1997-09-25 | Max Planck Gesellschaft | Schlafmittel |
| JP2000511538A (ja) * | 1996-05-24 | 2000-09-05 | スミスクライン・ビーチャム・コーポレイション | 鎮咳剤としてのgaba取り込み阻害剤の使用 |
| UA52661C2 (uk) * | 1996-06-14 | 2003-01-15 | Ново Нордіск А/С | Безводна кристалічна форма гідрохлориду r(-)-n-(4,4-ди(3-метилтієн-2-іл)бут-3-еніл) ніпекотинової кислоти |
| US5914333A (en) * | 1996-07-31 | 1999-06-22 | Novo Nordisk A/S | Treatment of psychotic disorders |
-
1998
- 1998-07-30 JP JP2000504859A patent/JP2001511450A/ja active Pending
- 1998-07-30 EP EP98937738A patent/EP0991409B1/en not_active Expired - Lifetime
- 1998-07-30 DE DE69803670T patent/DE69803670T2/de not_active Expired - Lifetime
- 1998-07-30 CA CA002299464A patent/CA2299464C/en not_active Expired - Fee Related
- 1998-07-30 AU AU86436/98A patent/AU8643698A/en not_active Abandoned
- 1998-07-30 AT AT98937738T patent/ATE212550T1/de active
- 1998-07-30 WO PCT/IE1998/000067 patent/WO1999006045A1/en not_active Ceased
- 1998-07-30 ES ES98937738T patent/ES2172179T3/es not_active Expired - Lifetime
- 1998-07-30 PT PT98937738T patent/PT991409E/pt unknown
- 1998-07-30 DK DK98937738T patent/DK0991409T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| ATE212550T1 (de) | 2002-02-15 |
| WO1999006045A1 (en) | 1999-02-11 |
| DK0991409T3 (da) | 2002-03-25 |
| PT991409E (pt) | 2002-06-28 |
| EP0991409B1 (en) | 2002-01-30 |
| CA2299464C (en) | 2009-02-17 |
| DE69803670D1 (de) | 2002-03-14 |
| AU8643698A (en) | 1999-02-22 |
| JP2001511450A (ja) | 2001-08-14 |
| DE69803670T2 (de) | 2002-11-21 |
| CA2299464A1 (en) | 1999-02-11 |
| EP0991409A1 (en) | 2000-04-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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