ES2166757T3 - Secuencias de adn del virus de epstein-barr que codifican un antigeno de la capsida del virus de interes diagnostico, clones de expresion obtenidos por la reaccion en cadena de la polimerasa y el uso de este antigeno recombinante en ensayos de diagnostico. - Google Patents

Secuencias de adn del virus de epstein-barr que codifican un antigeno de la capsida del virus de interes diagnostico, clones de expresion obtenidos por la reaccion en cadena de la polimerasa y el uso de este antigeno recombinante en ensayos de diagnostico.

Info

Publication number
ES2166757T3
ES2166757T3 ES93111883T ES93111883T ES2166757T3 ES 2166757 T3 ES2166757 T3 ES 2166757T3 ES 93111883 T ES93111883 T ES 93111883T ES 93111883 T ES93111883 T ES 93111883T ES 2166757 T3 ES2166757 T3 ES 2166757T3
Authority
ES
Spain
Prior art keywords
antigen
virus
epstein
capsida
chain reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93111883T
Other languages
English (en)
Inventor
Hans Prof Dr Wolf
Udo Dr Reischl
Manfred Dr Motz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2166757T3 publication Critical patent/ES2166757T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA APLICACION DESCRIBE LA IDENTIFICACION DE UN GEN CODIFICADO POR EL VIRUS DE EPSTEIN-BARR (VEB) Y METODOS RAPIDOS PARA LA CONSTRUCCION DE PLASMIDOS QUE EXPRESAN EFICIENTEMENTE ESTE U OTROS GENES. EL GEN VEB PUEDE ESTAR PURIFICADO Y SE UTILIZA COMO ANTIGENO PARA LA DIAGNOSIS Y LA TERAPIA DE LAS ENFERMEDADES RELACIONADAS CON EL VEB.
ES93111883T 1993-07-23 1993-07-23 Secuencias de adn del virus de epstein-barr que codifican un antigeno de la capsida del virus de interes diagnostico, clones de expresion obtenidos por la reaccion en cadena de la polimerasa y el uso de este antigeno recombinante en ensayos de diagnostico. Expired - Lifetime ES2166757T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93111883A EP0726315B1 (en) 1993-07-23 1993-07-23 Epstein-Barr virus DNA sequences encoding a diagnostically relevant virus capsid antigen, expression clones derived through polymerase chain reaction and the use of this recombinant antigen in diagnostic tests

Publications (1)

Publication Number Publication Date
ES2166757T3 true ES2166757T3 (es) 2002-05-01

Family

ID=8213107

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93111883T Expired - Lifetime ES2166757T3 (es) 1993-07-23 1993-07-23 Secuencias de adn del virus de epstein-barr que codifican un antigeno de la capsida del virus de interes diagnostico, clones de expresion obtenidos por la reaccion en cadena de la polimerasa y el uso de este antigeno recombinante en ensayos de diagnostico.

Country Status (10)

Country Link
US (1) US5741656A (es)
EP (1) EP0726315B1 (es)
JP (1) JPH09502864A (es)
CN (1) CN1117150C (es)
AT (1) ATE207120T1 (es)
AU (1) AU7495494A (es)
CZ (1) CZ20996A3 (es)
DE (1) DE69330966T2 (es)
ES (1) ES2166757T3 (es)
WO (1) WO1995003415A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19526384C2 (de) * 1995-07-19 1997-07-10 Biotest Ag Rekombinante autologe Fusionsproteine des Epstein-Barr-Virus, sowie diese enthaltende Testkits zum Nachweis von Epstein-Barr-Virus-spezifischen Antikörpern
DE69940770D1 (de) * 1998-03-04 2009-06-04 Biomerieux Bv Vervielfältigung und nachweis von ebv barf1 zur diagnose von nasopharyngealen karzinom
EP2759307B1 (en) 2006-03-29 2016-11-09 Merial Limited Vaccine against Streptococci
CN104139155A (zh) * 2013-05-06 2014-11-12 福特汽车公司 用于生成模具组件的模的添加制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3583564D1 (de) * 1984-08-23 1991-08-29 Hans Joachim Wolf Dna-sequenzen des ebv-genoms, rekombinante dna-molekuele, verfahren zur herstellung von ebv-verwandten antigenen sowie diagnostische zusammensetzungen und pharmazeutische zusammensetzungen, die die genannten antigene enthalten.
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
AU6164890A (en) * 1989-08-10 1991-03-11 Northwestern University Method of identifying herpesviruses and oligonucleotides for use therein
WO1991008224A1 (en) * 1989-11-24 1991-06-13 The Council Of The Queensland Institute Of Medical Research Im peptides
CZ283049B6 (cs) * 1989-12-20 1997-12-17 Schering Corporation Protein BCRF1 viru Epstein-Barr schopný inhibovat syntézu gama-interferonu, expresní vekter pro jeho syntézu a farmaceutický přípravek jej obsahující
DK0574048T3 (da) * 1992-03-13 2002-12-16 Organon Teknika Bv Peptider og nucleinsyresekvenser relateret til Epstein-Barr-virus

Also Published As

Publication number Publication date
CZ20996A3 (en) 1996-10-16
ATE207120T1 (de) 2001-11-15
DE69330966T2 (de) 2002-06-06
JPH09502864A (ja) 1997-03-25
EP0726315B1 (en) 2001-10-17
DE69330966D1 (de) 2001-11-22
US5741656A (en) 1998-04-21
WO1995003415A3 (en) 1995-03-16
CN1117150C (zh) 2003-08-06
WO1995003415A2 (en) 1995-02-02
AU7495494A (en) 1995-02-20
EP0726315A1 (en) 1996-08-14
CN1129460A (zh) 1996-08-21

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