ES2166757T3 - Secuencias de adn del virus de epstein-barr que codifican un antigeno de la capsida del virus de interes diagnostico, clones de expresion obtenidos por la reaccion en cadena de la polimerasa y el uso de este antigeno recombinante en ensayos de diagnostico. - Google Patents
Secuencias de adn del virus de epstein-barr que codifican un antigeno de la capsida del virus de interes diagnostico, clones de expresion obtenidos por la reaccion en cadena de la polimerasa y el uso de este antigeno recombinante en ensayos de diagnostico.Info
- Publication number
- ES2166757T3 ES2166757T3 ES93111883T ES93111883T ES2166757T3 ES 2166757 T3 ES2166757 T3 ES 2166757T3 ES 93111883 T ES93111883 T ES 93111883T ES 93111883 T ES93111883 T ES 93111883T ES 2166757 T3 ES2166757 T3 ES 2166757T3
- Authority
- ES
- Spain
- Prior art keywords
- antigen
- virus
- epstein
- capsida
- chain reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000427 antigen Substances 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 241000701044 Human gammaherpesvirus 4 Species 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- 238000003752 polymerase chain reaction Methods 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 238000010276 construction Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
- C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
LA APLICACION DESCRIBE LA IDENTIFICACION DE UN GEN CODIFICADO POR EL VIRUS DE EPSTEIN-BARR (VEB) Y METODOS RAPIDOS PARA LA CONSTRUCCION DE PLASMIDOS QUE EXPRESAN EFICIENTEMENTE ESTE U OTROS GENES. EL GEN VEB PUEDE ESTAR PURIFICADO Y SE UTILIZA COMO ANTIGENO PARA LA DIAGNOSIS Y LA TERAPIA DE LAS ENFERMEDADES RELACIONADAS CON EL VEB.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93111883A EP0726315B1 (en) | 1993-07-23 | 1993-07-23 | Epstein-Barr virus DNA sequences encoding a diagnostically relevant virus capsid antigen, expression clones derived through polymerase chain reaction and the use of this recombinant antigen in diagnostic tests |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2166757T3 true ES2166757T3 (es) | 2002-05-01 |
Family
ID=8213107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93111883T Expired - Lifetime ES2166757T3 (es) | 1993-07-23 | 1993-07-23 | Secuencias de adn del virus de epstein-barr que codifican un antigeno de la capsida del virus de interes diagnostico, clones de expresion obtenidos por la reaccion en cadena de la polimerasa y el uso de este antigeno recombinante en ensayos de diagnostico. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5741656A (es) |
EP (1) | EP0726315B1 (es) |
JP (1) | JPH09502864A (es) |
CN (1) | CN1117150C (es) |
AT (1) | ATE207120T1 (es) |
AU (1) | AU7495494A (es) |
CZ (1) | CZ20996A3 (es) |
DE (1) | DE69330966T2 (es) |
ES (1) | ES2166757T3 (es) |
WO (1) | WO1995003415A2 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19526384C2 (de) * | 1995-07-19 | 1997-07-10 | Biotest Ag | Rekombinante autologe Fusionsproteine des Epstein-Barr-Virus, sowie diese enthaltende Testkits zum Nachweis von Epstein-Barr-Virus-spezifischen Antikörpern |
DE69940770D1 (de) * | 1998-03-04 | 2009-06-04 | Biomerieux Bv | Vervielfältigung und nachweis von ebv barf1 zur diagnose von nasopharyngealen karzinom |
EP2759307B1 (en) | 2006-03-29 | 2016-11-09 | Merial Limited | Vaccine against Streptococci |
CN104139155A (zh) * | 2013-05-06 | 2014-11-12 | 福特汽车公司 | 用于生成模具组件的模的添加制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3583564D1 (de) * | 1984-08-23 | 1991-08-29 | Hans Joachim Wolf | Dna-sequenzen des ebv-genoms, rekombinante dna-molekuele, verfahren zur herstellung von ebv-verwandten antigenen sowie diagnostische zusammensetzungen und pharmazeutische zusammensetzungen, die die genannten antigene enthalten. |
US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
AU6164890A (en) * | 1989-08-10 | 1991-03-11 | Northwestern University | Method of identifying herpesviruses and oligonucleotides for use therein |
WO1991008224A1 (en) * | 1989-11-24 | 1991-06-13 | The Council Of The Queensland Institute Of Medical Research | Im peptides |
CZ283049B6 (cs) * | 1989-12-20 | 1997-12-17 | Schering Corporation | Protein BCRF1 viru Epstein-Barr schopný inhibovat syntézu gama-interferonu, expresní vekter pro jeho syntézu a farmaceutický přípravek jej obsahující |
DK0574048T3 (da) * | 1992-03-13 | 2002-12-16 | Organon Teknika Bv | Peptider og nucleinsyresekvenser relateret til Epstein-Barr-virus |
-
1993
- 1993-07-23 ES ES93111883T patent/ES2166757T3/es not_active Expired - Lifetime
- 1993-07-23 AT AT93111883T patent/ATE207120T1/de active
- 1993-07-23 DE DE69330966T patent/DE69330966T2/de not_active Expired - Lifetime
- 1993-07-23 EP EP93111883A patent/EP0726315B1/en not_active Expired - Lifetime
-
1994
- 1994-07-22 JP JP7504952A patent/JPH09502864A/ja active Pending
- 1994-07-22 AU AU74954/94A patent/AU7495494A/en not_active Abandoned
- 1994-07-22 US US08/586,640 patent/US5741656A/en not_active Expired - Lifetime
- 1994-07-22 CZ CZ96209A patent/CZ20996A3/cs unknown
- 1994-07-22 CN CN94193098A patent/CN1117150C/zh not_active Expired - Lifetime
- 1994-07-22 WO PCT/EP1994/002436 patent/WO1995003415A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CZ20996A3 (en) | 1996-10-16 |
ATE207120T1 (de) | 2001-11-15 |
DE69330966T2 (de) | 2002-06-06 |
JPH09502864A (ja) | 1997-03-25 |
EP0726315B1 (en) | 2001-10-17 |
DE69330966D1 (de) | 2001-11-22 |
US5741656A (en) | 1998-04-21 |
WO1995003415A3 (en) | 1995-03-16 |
CN1117150C (zh) | 2003-08-06 |
WO1995003415A2 (en) | 1995-02-02 |
AU7495494A (en) | 1995-02-20 |
EP0726315A1 (en) | 1996-08-14 |
CN1129460A (zh) | 1996-08-21 |
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