ES2164259T3 - Procedimiento para la obtencion de amidas de los acidos alfa-(n,n-dialquil)-aminocarboxilicos. - Google Patents
Procedimiento para la obtencion de amidas de los acidos alfa-(n,n-dialquil)-aminocarboxilicos.Info
- Publication number
- ES2164259T3 ES2164259T3 ES96925746T ES96925746T ES2164259T3 ES 2164259 T3 ES2164259 T3 ES 2164259T3 ES 96925746 T ES96925746 T ES 96925746T ES 96925746 T ES96925746 T ES 96925746T ES 2164259 T3 ES2164259 T3 ES 2164259T3
- Authority
- ES
- Spain
- Prior art keywords
- dialquil
- procedure
- acids
- aminocarboxyl
- alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 150000007513 acids Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001408 amides Chemical class 0.000 title 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
- C07K1/082—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing phosphorus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Abstract
SE DESCRIBE UN PROCEDIMIENTO PARA LA FABRICACION DE AL} (N,N DIALQUIL) AMIDAS DEL ACIDO AMINOCARBOXILICO DE FORMULA (I), EN LA CUAL LOS SUSTITUYENTES POSEEN LA SIGNIFICACION DADA Y QUE CONSISTE EN QUE LOS ACIDOS LIBRES CORRESPONDIENTES SE HACEN REACCIONAR CON AMINAS PRIMARIAS O SECUNDARIAS EN PRESENCIA DE ANHIDRIDOS DE UN ACIDO ALCANOFOSFONICO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19527574A DE19527574A1 (de) | 1995-07-28 | 1995-07-28 | Verfahren zur Herstellung vona-(N,N-Dialkyl)-aminocaarbonsäureamiden |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2164259T3 true ES2164259T3 (es) | 2002-02-16 |
Family
ID=7767994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96925746T Expired - Lifetime ES2164259T3 (es) | 1995-07-28 | 1996-07-12 | Procedimiento para la obtencion de amidas de los acidos alfa-(n,n-dialquil)-aminocarboxilicos. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5945543A (es) |
EP (1) | EP0842142B1 (es) |
JP (1) | JPH11509851A (es) |
KR (1) | KR100445961B1 (es) |
AT (1) | ATE206106T1 (es) |
AU (1) | AU704270B2 (es) |
CA (1) | CA2223872A1 (es) |
CZ (1) | CZ292229B6 (es) |
DE (2) | DE19527574A1 (es) |
ES (1) | ES2164259T3 (es) |
HU (1) | HUP9802403A3 (es) |
IL (1) | IL122397A0 (es) |
TW (1) | TW403733B (es) |
WO (1) | WO1997005096A1 (es) |
ZA (1) | ZA966372B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2266607A3 (en) | 1999-10-01 | 2011-04-20 | Immunogen, Inc. | Immunoconjugates for treating cancer |
AU2003237595A1 (en) * | 2003-05-26 | 2004-12-13 | Biocon Limited | Process for the preparation of s(+)-2-ethoxy-4-(n-{1-(2-piperidinophelyl)-3-methyl-1- butyl} aminocarbonylmethyl)benzoic acid derivatives |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1972142A (en) * | 1931-04-07 | 1934-09-04 | Ici Ltd | Process for the production of carboxylic acid amides |
DE2901843A1 (de) * | 1979-01-18 | 1980-07-31 | Hoechst Ag | Verfahren zur herstellung von carbonsaeureamiden und peptiden |
DE3101427A1 (de) * | 1981-01-17 | 1982-09-02 | Hoechst Ag, 6000 Frankfurt | "verfahren zur herstellung von carbonsaeureamidgruppen enthaltenden verbindungen, insbesondere von peptiden" |
DE3411224A1 (de) * | 1984-03-27 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren |
DE3712365A1 (de) * | 1987-04-11 | 1988-10-27 | Hoechst Ag | Neue 2-acylpyrrolidin-derivate, verfahren zu ihrer herstellung, sie enthaltende mittel sowie deren verwendung |
CA2136339C (en) * | 1992-05-20 | 2008-02-05 | Andreas Haupt | Derivatives of dolastatin |
-
1995
- 1995-07-28 DE DE19527574A patent/DE19527574A1/de not_active Withdrawn
-
1996
- 1996-07-12 JP JP9507162A patent/JPH11509851A/ja not_active Withdrawn
- 1996-07-12 US US08/983,287 patent/US5945543A/en not_active Expired - Fee Related
- 1996-07-12 AU AU66155/96A patent/AU704270B2/en not_active Ceased
- 1996-07-12 ES ES96925746T patent/ES2164259T3/es not_active Expired - Lifetime
- 1996-07-12 CA CA002223872A patent/CA2223872A1/en not_active Abandoned
- 1996-07-12 EP EP96925746A patent/EP0842142B1/de not_active Expired - Lifetime
- 1996-07-12 CZ CZ199889A patent/CZ292229B6/cs not_active IP Right Cessation
- 1996-07-12 WO PCT/EP1996/003075 patent/WO1997005096A1/de active IP Right Grant
- 1996-07-12 KR KR10-1998-0700637A patent/KR100445961B1/ko not_active IP Right Cessation
- 1996-07-12 DE DE59607794T patent/DE59607794D1/de not_active Expired - Lifetime
- 1996-07-12 IL IL12239796A patent/IL122397A0/xx not_active IP Right Cessation
- 1996-07-12 HU HU9802403A patent/HUP9802403A3/hu unknown
- 1996-07-12 AT AT96925746T patent/ATE206106T1/de not_active IP Right Cessation
- 1996-07-19 TW TW085108766A patent/TW403733B/zh not_active IP Right Cessation
- 1996-07-26 ZA ZA9606372A patent/ZA966372B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
KR100445961B1 (ko) | 2004-10-14 |
HUP9802403A3 (en) | 1999-03-29 |
DE19527574A1 (de) | 1997-01-30 |
KR19990035976A (ko) | 1999-05-25 |
WO1997005096A1 (de) | 1997-02-13 |
EP0842142A1 (de) | 1998-05-20 |
CA2223872A1 (en) | 1997-02-13 |
CZ292229B6 (cs) | 2003-08-13 |
ATE206106T1 (de) | 2001-10-15 |
IL122397A0 (en) | 1998-06-15 |
AU704270B2 (en) | 1999-04-15 |
JPH11509851A (ja) | 1999-08-31 |
TW403733B (en) | 2000-09-01 |
DE59607794D1 (de) | 2001-10-31 |
US5945543A (en) | 1999-08-31 |
HUP9802403A2 (hu) | 1999-02-01 |
AU6615596A (en) | 1997-02-26 |
CZ8998A3 (cs) | 1998-06-17 |
ZA966372B (en) | 1998-01-26 |
EP0842142B1 (de) | 2001-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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