ES2157912T3 - Membrana y metodo para la separacion de sustancias unidas a proteinas de un liquido que contiene proteinas mediante dialisis. - Google Patents
Membrana y metodo para la separacion de sustancias unidas a proteinas de un liquido que contiene proteinas mediante dialisis.Info
- Publication number
- ES2157912T3 ES2157912T3 ES93115029T ES93115029T ES2157912T3 ES 2157912 T3 ES2157912 T3 ES 2157912T3 ES 93115029 T ES93115029 T ES 93115029T ES 93115029 T ES93115029 T ES 93115029T ES 2157912 T3 ES2157912 T3 ES 2157912T3
- Authority
- ES
- Spain
- Prior art keywords
- liquid
- dialized
- membrane
- proteins
- pbs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007788 liquid Substances 0.000 title abstract 11
- 108090000623 proteins and genes Proteins 0.000 title abstract 9
- 102000004169 proteins and genes Human genes 0.000 title abstract 9
- 239000012528 membrane Substances 0.000 title abstract 5
- 239000000126 substance Substances 0.000 title abstract 5
- 238000000502 dialysis Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000000926 separation method Methods 0.000 title abstract 2
- 101100331550 Antirrhinum majus DICH gene Proteins 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-PWCQTSIFSA-N Tritiated water Chemical compound [3H]O[3H] XLYOFNOQVPJJNP-PWCQTSIFSA-N 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/24—Dialysis ; Membrane extraction
- B01D61/243—Dialysis
- B01D61/244—Dialysis comprising multiple dialysis steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1654—Dialysates therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1694—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid
- A61M1/1696—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid with dialysate regeneration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3475—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate with filtrate treatment agent in the same enclosure as the membrane
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
- Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Water Supply & Treatment (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Peptides Or Proteins (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN METODO PARA LA SEPARACION POR DIALISIS DE SUSTANCIAS LIGADAS A PROTEINAS (PBS) Y, SI ESTAN PRESENTES, SUSTANCIAS SOLUBLES EN AGUA, DE UN LIQUIDO QUE CONTIENE PROTEINAS (A), POR EJEMPLO, SANGRE O PLASMA CON DICHAS SUSTANCIAS, USANDO UNA MEMBRANA ESPECIAL SEMIPERMEABLE Y UN LIQUIDO DIALIZADO (B) GRACIAS A QUE LA PROTEINA TIENE UN FUNCION DE ACEPTACION PARA LAS PBS DEL LIQUIDO. LA MEMBRANA UTIL PARA ESTE METODO TIENE QUE APORTAR UNA ESTRUCTURA POROSA EN FORMA DE TUNEL SOBRE EL LADO DEL LIQUIDO (A) Y UNA ESTRUCTURA DE ABSORCION Y PORTADORA SOBRE EL LADO DEL LIQUIDO DIALIZADO (B). UNA O AMBAS CARAS DE LA MEMBRANA, POR EJEMPLO EL LADO DEL LIQUIDO QUE CONTIENE PROTEINAS (A) Y EL LADO DEL LIQUIDO DIALIZADO (B) DE LA MEMBRANA, ESTAN RECUBIERTAS DE UNA PROTEINA QUE TIENE UNA FUNCION DE ACEPTACION DE PBS. EL LIQUIDO DIALIZADO (B) QUE CONTIENE PBS OBTENIDO DESPUES DE LA DIALISIS PUEDE ENTONCES SER PURIFICADO A BASE DE PASARLO A TRAVES DE UN DIALIZADOR CONVENCIONALDE CARA A RETIRAR LA SUSTANCIAS SOLUBLES EN AGUA Y DESPUES A TRAVES DE UN ABSORBENTE DE CARBON Y RESINA DE CARA A RETIRAR LAS PBS DE LAS MOLECULAS DEL ACEPTADOR DE PROTEINA. EL LIQUIDO DIALIZADO PURIFICADO (B) OBTENIDO QUE CONTIENE LAS MOLECULAS LIBRES DEL ACEPTADOR DE PROTEINAS SE PUEDE ENTONCES USAR DE NUEVO COMO LIQUIDO DIALIZADO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4309410A DE4309410A1 (de) | 1993-03-19 | 1993-03-19 | Material, Verfahren und Einrichtung zur selektiven Trennung frei gelöster und stoffgebundener Stoffe aus flüssigen Stoffgemischen sowie Verfahren zur Herstellung des Materials |
US08/570,816 US5744042A (en) | 1993-03-19 | 1995-12-12 | Method for the separation of protein-bound substances from a protein-containing liquid by dialysis |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2157912T3 true ES2157912T3 (es) | 2001-09-01 |
Family
ID=25924257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93115029T Expired - Lifetime ES2157912T3 (es) | 1993-03-19 | 1993-09-17 | Membrana y metodo para la separacion de sustancias unidas a proteinas de un liquido que contiene proteinas mediante dialisis. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5744042A (es) |
EP (1) | EP0615780B1 (es) |
JP (2) | JP3486190B2 (es) |
AT (1) | ATE200741T1 (es) |
DE (2) | DE4309410A1 (es) |
ES (1) | ES2157912T3 (es) |
WO (1) | WO1994021363A1 (es) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
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JP4177898B2 (ja) * | 1996-10-22 | 2008-11-05 | リーナル・ソリューションズ・インコーポレーテッド | 腹腔内圧を制御した連続式フロースルー腹膜透析(cfpd)法 |
DE19705366C2 (de) * | 1997-02-12 | 2002-08-01 | Fresenius Ag | Trägermaterial zur Reinigung proteinhaltiger Lösungen, Verfahren zur Herstellung des Trägermaterials und Verwendung des Trägermaterials |
EP0958832B1 (en) * | 1998-05-21 | 2006-01-25 | Nipro Corporation | Albumin containing peritoneal dialysis fluid |
JP4061775B2 (ja) * | 1998-05-21 | 2008-03-19 | ニプロ株式会社 | アルブミン含有腹膜透析液 |
US20040199099A1 (en) * | 1998-07-10 | 2004-10-07 | Matson James R | Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease |
US6287516B1 (en) * | 1998-07-10 | 2001-09-11 | Immunocept, L.L.C. | Hemofiltration systems, methods, and devices used to treat inflammatory mediator related disease |
CA2338952C (en) | 1998-07-31 | 2007-04-03 | Nephros, Inc. | Method for efficient hemodiafiltration |
AU1604800A (en) | 1998-10-30 | 2000-05-22 | Nephros, Inc. | Non-isosmotic diafiltration system |
US6635179B1 (en) | 1999-12-30 | 2003-10-21 | Nephros, Inc. | Sterile fluid filtration cartridge and method for using same |
ATE387949T1 (de) * | 2000-01-11 | 2008-03-15 | Nephros Inc | Hämodiafiltrationsgerät zur blutdialyse |
US7067060B2 (en) * | 2000-01-11 | 2006-06-27 | Nephros, Inc. | Ionic enhanced dialysis/diafiltration system |
WO2001058496A1 (en) * | 2000-02-11 | 2001-08-16 | Allied Therapeutics Limited | System for the extracorporeal treatment of blood |
US7291122B2 (en) * | 2000-03-24 | 2007-11-06 | Immunocept, L.L.C. | Hemofiltration methods for treatment of diseases in a mammal |
US8535258B2 (en) * | 2000-03-24 | 2013-09-17 | Immunocept, L.L.C. | Hemofiltration methods for treatment of diseases in a mammal |
US6736972B1 (en) | 2000-03-24 | 2004-05-18 | Immunocept, L.L.C. | Method and system for providing therapeutic agents with hemofiltration for reducing inflammatory mediator related diseases |
US6602414B2 (en) * | 2000-03-30 | 2003-08-05 | Formulations Pro | Molecule separation device and method combining multiple filtration media |
US8597516B2 (en) * | 2000-05-16 | 2013-12-03 | Immunocept, L.L.C. | Methods and systems for colloid exchange therapy |
US6787040B2 (en) * | 2000-05-16 | 2004-09-07 | Immunocept, L.L.C. | Method and system for colloid exchange therapy |
ATE457817T1 (de) | 2000-10-30 | 2010-03-15 | Nephros Inc | Zweistufige filterpatrone |
US7241272B2 (en) * | 2001-11-13 | 2007-07-10 | Baxter International Inc. | Method and composition for removing uremic toxins in dialysis processes |
SE522692C2 (sv) * | 2002-03-27 | 2004-03-02 | Gambro Lundia Ab | Förfarande och anordning för avlägsnande av delvis proteinbundna substanser |
EP1362605A1 (de) * | 2002-05-14 | 2003-11-19 | Bernhard Dr. Kreymann | Dialysevorrichtung zur Entfernung proteingebundener Substanzen |
US7455771B2 (en) | 2002-05-14 | 2008-11-25 | Hepa Wash Gmbh | Means for removing protein-bound substances |
ATE509645T1 (de) * | 2002-07-19 | 2011-06-15 | Baxter Int | Vorrichtungen und verfahren zur peritonealdialyse |
AU2003249297A1 (en) * | 2002-07-19 | 2004-02-09 | Baxter Healthcare S.A. | Systems and methods for peritoneal dialysis |
JP4890761B2 (ja) * | 2002-07-19 | 2012-03-07 | バクスター・インターナショナル・インコーポレイテッド | 腹膜透析を実施するためのシステムおよび方法 |
WO2004014315A2 (en) * | 2002-08-13 | 2004-02-19 | Arbios Systems, Inc. | Selective plasma exchange therapy |
US20040217055A1 (en) * | 2003-03-12 | 2004-11-04 | Elmar Kraus | Use of recombinant albumin in dialysis after liver failure |
US20060076295A1 (en) * | 2004-03-15 | 2006-04-13 | The Trustees Of Columbia University In The City Of New York | Systems and methods of blood-based therapies having a microfluidic membraneless exchange device |
CA2518667C (en) * | 2003-03-14 | 2011-07-19 | The Trustees Of Columbia University In The City Of New York | Systems and methods of blood-based therapies having a microfluidic membraneless exchange device |
DE10324668A1 (de) * | 2003-05-30 | 2004-12-23 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung zur extrakorporalen Bestrahlung einer Bilirubin enthaltenden Flüssigkeit und Verfahren hierfür |
US20050037331A1 (en) * | 2003-08-13 | 2005-02-17 | William Galbraith | Apparatuses and methods for reducing albumin in samples |
US20050045554A1 (en) | 2003-08-28 | 2005-03-03 | Gambro Lundia Ab | Membrane unit element, semipermeable membrane, filtration device, and processes for manufacturing the same |
CA2575731C (en) * | 2003-12-24 | 2014-07-15 | Chemica Technologies, Inc. | Dialysate regeneration system for portable human dialysis |
JP3980588B2 (ja) * | 2004-01-27 | 2007-09-26 | 独立行政法人科学技術振興機構 | 血漿交換廃液浄化循環透析装置 |
US8038638B2 (en) * | 2004-02-23 | 2011-10-18 | Hemolife Medical, Inc. | Plasma detoxification and volume control system and methods of use |
US7534349B2 (en) * | 2005-09-02 | 2009-05-19 | Nephros, Inc. | Dual stage ultrafilter devices in the form of portable filter devices, shower devices, and hydration packs |
US7775375B2 (en) * | 2005-11-03 | 2010-08-17 | Medica S.R.L. | Redundant ultrafiltration device |
US20100168000A1 (en) * | 2005-12-22 | 2010-07-01 | Peter Kiessling | Octanoate-Reduced Human Albumin |
CN100457203C (zh) * | 2006-01-10 | 2009-02-04 | 赵滨宇 | 血液透析循环装置 |
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WO2007137245A2 (en) | 2006-05-22 | 2007-11-29 | Columbia University | Systems and methods of microfluidic membraneless exchange using filtration of extraction fluid outlet streams |
JP4947693B2 (ja) * | 2006-07-14 | 2012-06-06 | 学校法人北里研究所 | アルブミンとアルブミンに結合した生体分子の分離方法 |
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EP1944046B1 (en) * | 2007-01-12 | 2010-08-11 | Bellco S.r.l. | Kit for treating a systematic inflammation related diseases |
DE102007039939B4 (de) | 2007-08-23 | 2013-03-14 | Albutec Gmbh | Vorrichtung zur Einsparung von Diafiltrat |
JP5208220B2 (ja) * | 2007-12-03 | 2013-06-12 | ヘパ ウォッシュ ゲゼルシャフト ミット ベシュレンクテル ハフツング | 透析液再生ユニット |
BRPI0907473A2 (pt) | 2008-02-04 | 2019-09-24 | Univ Columbia | métodos, sistemas e dispositivos de separação de fluidos |
EP2273995B2 (en) * | 2008-03-20 | 2023-11-15 | Baxter International Inc. | Destruction of microbial products by enzymatic digestion |
US8057679B2 (en) | 2008-07-09 | 2011-11-15 | Baxter International Inc. | Dialysis system having trending and alert generation |
US20100051552A1 (en) | 2008-08-28 | 2010-03-04 | Baxter International Inc. | In-line sensors for dialysis applications |
WO2010045474A2 (en) | 2008-10-16 | 2010-04-22 | Fresenius Medical Care Holdings, Inc. | Method of removing protein-bound deleterious substances during extracorporeal renal replacement treatment |
EP2380610B1 (en) | 2010-04-20 | 2014-05-07 | Gambro Lundia AB | High cut-off hemodialysis membrane for use in liver dialysis |
ES2550798T3 (es) * | 2010-11-10 | 2015-11-12 | Gambro Lundia Ab | Dispositivo para el tratamiento de sangre con extracción selectiva de solutos |
DE102011078700A1 (de) * | 2011-07-05 | 2013-01-10 | Charité - Universitätsmedizin Berlin | Dialyseverfahren zur Entfernung proteingebundener Toxine aus dem Blut von akut oder chronisch-niereninsuffizienten Patienten |
EP2606921A1 (fr) * | 2011-12-21 | 2013-06-26 | Infomed SA | Dispositif d'épuration du sang par circulation extracorporelle |
EP2730303B1 (en) * | 2012-11-08 | 2015-08-12 | Gambro Lundia AB | Albumin pump control in a MARS treatment apparatus |
EP2735359B1 (en) | 2012-11-26 | 2017-02-08 | Gambro Lundia AB | Integrated device for liver support systems |
ES2626754T3 (es) | 2012-11-26 | 2017-07-25 | Gambro Lundia Ab | Dispositivo de adsorción que combina perlas y membranas de fibra hueca |
ES2625510T3 (es) | 2012-11-26 | 2017-07-19 | Gambro Lundia Ab | Sistema de soporte hepático |
DE102013218239A1 (de) | 2013-08-05 | 2015-02-19 | Tetec Tissue Engineering Technologies Ag | Verfahren zur Herstellung eines Produktes mittels Dialyse |
EP3102224B1 (en) * | 2013-12-20 | 2019-02-20 | NephroGenesis, LLC. | Apparatuses for kidney dialysis and lipocalin protein for use in the prevention or treatment of uremia by dialysis |
JP2018524718A (ja) | 2015-06-25 | 2018-08-30 | ガンブロ・ルンディア・エービーGambro Lundia Ab | 分散データベースを有する医療装置システム及び方法 |
US9814822B2 (en) * | 2015-08-27 | 2017-11-14 | Fresenius Medical Care Holdings, Inc. | Plasma generation with dialysis systems |
WO2017084683A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal lung support |
WO2017084682A1 (en) | 2015-11-20 | 2017-05-26 | Hepa Wash Gmbh | Method for extracorporeal carbon dioxide removal |
JP6896757B2 (ja) * | 2015-12-04 | 2021-06-30 | キドニ ラボズ, インク.Qidni Labs, Inc. | 埋込型腎代替療法システム |
DK3429657T3 (da) | 2016-03-14 | 2022-06-13 | Advitos Gmbh | Systemer eller apparater til at udføre dialyse. |
EP3290067B1 (en) | 2016-09-06 | 2021-03-03 | Gambro Lundia AB | Liver support system |
BR112019012719A2 (pt) | 2016-12-21 | 2019-11-26 | Gambro Lundia Ab | sistema de dispositivo médico incluindo infraestrutura de tecnologia de informação tendo domínio de agrupamento seguro suportando domínio externo |
CA3075994A1 (en) | 2017-05-22 | 2018-11-29 | Advitos Gmbh | Methods and systems for removing carbon dioxide |
US10391220B2 (en) | 2018-01-12 | 2019-08-27 | Fresnius Medical Care Holdings, Inc. | Virtual kidney donation |
WO2021138461A1 (en) * | 2019-12-31 | 2021-07-08 | Seastar Medical, Inc. | Devices and methods for reducing rejection of a transplanted organ in a recipient |
CA3187610A1 (en) | 2020-07-08 | 2022-01-13 | Fresenius Medical Care Deutschland Gmbh | Parabiotic dialysis systems and techniques |
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US4375414A (en) * | 1971-05-20 | 1983-03-01 | Meir Strahilevitz | Immunological methods for removing species from the blood circulatory system and devices therefor |
US4163714A (en) * | 1975-11-07 | 1979-08-07 | Gregor Harry P | Separating substances with pressure-driven affinity sorption membranes |
US5328614A (en) * | 1979-05-21 | 1994-07-12 | Matsumura Kenneth N | Methods and apparati for removing protein-bound molecules from body fluids |
US5078885A (en) * | 1983-06-01 | 1992-01-07 | Matsumura Kenneth N | Method and apparatus for removing protein-bound molecules from body fluids |
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DE3230540A1 (de) * | 1982-08-17 | 1984-02-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München | Verfahren und vorrichtung zur entfernung von protein- oder lipidgebundenen toxinen aus blut oder blutfraktionen |
US4741832A (en) * | 1984-05-15 | 1988-05-03 | The Trustees Of Columbia, University In The City Of New York | Purification apparatus and method employing a regenerable ligand |
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US5167824A (en) * | 1990-02-14 | 1992-12-01 | Creative Biomolecules, Inc. | Separation by carrier mediated transport |
-
1993
- 1993-03-19 DE DE4309410A patent/DE4309410A1/de not_active Withdrawn
- 1993-09-17 EP EP93115029A patent/EP0615780B1/en not_active Expired - Lifetime
- 1993-09-17 DE DE69330179T patent/DE69330179T2/de not_active Expired - Lifetime
- 1993-09-17 ES ES93115029T patent/ES2157912T3/es not_active Expired - Lifetime
- 1993-09-17 AT AT93115029T patent/ATE200741T1/de not_active IP Right Cessation
-
1994
- 1994-03-17 JP JP52038294A patent/JP3486190B2/ja not_active Expired - Fee Related
- 1994-03-17 WO PCT/IB1994/000073 patent/WO1994021363A1/en unknown
-
1995
- 1995-12-12 US US08/570,816 patent/US5744042A/en not_active Expired - Lifetime
-
2003
- 2003-05-08 JP JP2003130407A patent/JP2003299730A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US5744042A (en) | 1998-04-28 |
DE4309410A1 (de) | 1995-02-16 |
JPH07506765A (ja) | 1995-07-27 |
DE69330179D1 (de) | 2001-05-31 |
JP3486190B2 (ja) | 2004-01-13 |
ATE200741T1 (de) | 2001-05-15 |
DE69330179T2 (de) | 2001-11-08 |
EP0615780B1 (en) | 2001-04-25 |
JP2003299730A (ja) | 2003-10-21 |
EP0615780A1 (en) | 1994-09-21 |
WO1994021363A1 (en) | 1994-09-29 |
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