ES2157912T3 - Membrana y metodo para la separacion de sustancias unidas a proteinas de un liquido que contiene proteinas mediante dialisis. - Google Patents

Membrana y metodo para la separacion de sustancias unidas a proteinas de un liquido que contiene proteinas mediante dialisis.

Info

Publication number
ES2157912T3
ES2157912T3 ES93115029T ES93115029T ES2157912T3 ES 2157912 T3 ES2157912 T3 ES 2157912T3 ES 93115029 T ES93115029 T ES 93115029T ES 93115029 T ES93115029 T ES 93115029T ES 2157912 T3 ES2157912 T3 ES 2157912T3
Authority
ES
Spain
Prior art keywords
liquid
dialized
membrane
proteins
pbs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93115029T
Other languages
English (en)
Inventor
Jan Dr Med Stange
Steffen Dr Med Mitzner
Wolfgang Dr Med Ramlow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teraklin AG
Original Assignee
Teraklin AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teraklin AG filed Critical Teraklin AG
Application granted granted Critical
Publication of ES2157912T3 publication Critical patent/ES2157912T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/243—Dialysis
    • B01D61/244—Dialysis comprising multiple dialysis steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/243—Dialysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1694—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid
    • A61M1/1696—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes with recirculating dialysing liquid with dialysate regeneration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3475—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate with filtrate treatment agent in the same enclosure as the membrane
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14—Dynamic membranes
    • B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Water Supply & Treatment (AREA)
  • Dispersion Chemistry (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN METODO PARA LA SEPARACION POR DIALISIS DE SUSTANCIAS LIGADAS A PROTEINAS (PBS) Y, SI ESTAN PRESENTES, SUSTANCIAS SOLUBLES EN AGUA, DE UN LIQUIDO QUE CONTIENE PROTEINAS (A), POR EJEMPLO, SANGRE O PLASMA CON DICHAS SUSTANCIAS, USANDO UNA MEMBRANA ESPECIAL SEMIPERMEABLE Y UN LIQUIDO DIALIZADO (B) GRACIAS A QUE LA PROTEINA TIENE UN FUNCION DE ACEPTACION PARA LAS PBS DEL LIQUIDO. LA MEMBRANA UTIL PARA ESTE METODO TIENE QUE APORTAR UNA ESTRUCTURA POROSA EN FORMA DE TUNEL SOBRE EL LADO DEL LIQUIDO (A) Y UNA ESTRUCTURA DE ABSORCION Y PORTADORA SOBRE EL LADO DEL LIQUIDO DIALIZADO (B). UNA O AMBAS CARAS DE LA MEMBRANA, POR EJEMPLO EL LADO DEL LIQUIDO QUE CONTIENE PROTEINAS (A) Y EL LADO DEL LIQUIDO DIALIZADO (B) DE LA MEMBRANA, ESTAN RECUBIERTAS DE UNA PROTEINA QUE TIENE UNA FUNCION DE ACEPTACION DE PBS. EL LIQUIDO DIALIZADO (B) QUE CONTIENE PBS OBTENIDO DESPUES DE LA DIALISIS PUEDE ENTONCES SER PURIFICADO A BASE DE PASARLO A TRAVES DE UN DIALIZADOR CONVENCIONALDE CARA A RETIRAR LA SUSTANCIAS SOLUBLES EN AGUA Y DESPUES A TRAVES DE UN ABSORBENTE DE CARBON Y RESINA DE CARA A RETIRAR LAS PBS DE LAS MOLECULAS DEL ACEPTADOR DE PROTEINA. EL LIQUIDO DIALIZADO PURIFICADO (B) OBTENIDO QUE CONTIENE LAS MOLECULAS LIBRES DEL ACEPTADOR DE PROTEINAS SE PUEDE ENTONCES USAR DE NUEVO COMO LIQUIDO DIALIZADO.
ES93115029T 1993-03-19 1993-09-17 Membrana y metodo para la separacion de sustancias unidas a proteinas de un liquido que contiene proteinas mediante dialisis. Expired - Lifetime ES2157912T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4309410A DE4309410A1 (de) 1993-03-19 1993-03-19 Material, Verfahren und Einrichtung zur selektiven Trennung frei gelöster und stoffgebundener Stoffe aus flüssigen Stoffgemischen sowie Verfahren zur Herstellung des Materials
US08/570,816 US5744042A (en) 1993-03-19 1995-12-12 Method for the separation of protein-bound substances from a protein-containing liquid by dialysis

Publications (1)

Publication Number Publication Date
ES2157912T3 true ES2157912T3 (es) 2001-09-01

Family

ID=25924257

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93115029T Expired - Lifetime ES2157912T3 (es) 1993-03-19 1993-09-17 Membrana y metodo para la separacion de sustancias unidas a proteinas de un liquido que contiene proteinas mediante dialisis.

Country Status (7)

Country Link
US (1) US5744042A (es)
EP (1) EP0615780B1 (es)
JP (2) JP3486190B2 (es)
AT (1) ATE200741T1 (es)
DE (2) DE4309410A1 (es)
ES (1) ES2157912T3 (es)
WO (1) WO1994021363A1 (es)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998017333A2 (en) * 1996-10-22 1998-04-30 Hemocleanse, Inc. Continuous flow-through peritoneal dialysis (cfpd) method with control of intraperitoneal pressure
DE19705366C2 (de) * 1997-02-12 2002-08-01 Fresenius Ag Trägermaterial zur Reinigung proteinhaltiger Lösungen, Verfahren zur Herstellung des Trägermaterials und Verwendung des Trägermaterials
ATE316383T1 (de) * 1998-05-21 2006-02-15 Nipro Corp Albumin enthaltende lösung für die peritonealdialyse
JP4061775B2 (ja) * 1998-05-21 2008-03-19 ニプロ株式会社 アルブミン含有腹膜透析液
US20040199099A1 (en) * 1998-07-10 2004-10-07 Matson James R Hemofiltration systems, methods and devices used to treat inflammatory mediator related disease
US6287516B1 (en) * 1998-07-10 2001-09-11 Immunocept, L.L.C. Hemofiltration systems, methods, and devices used to treat inflammatory mediator related disease
ES2324506T3 (es) 1998-07-31 2009-08-07 Nephros, Inc. Dispositivo para hemodiafiltracion eficaz.
JP4436569B2 (ja) 1998-10-30 2010-03-24 ネフロス・インコーポレーテッド 浸透圧差による透過型濾過システム
US6635179B1 (en) 1999-12-30 2003-10-21 Nephros, Inc. Sterile fluid filtration cartridge and method for using same
DE60133148T2 (de) * 2000-01-11 2009-09-10 Nephros, Inc. Hämodialfiltrationsgerät zur Blutanalyse
US7067060B2 (en) * 2000-01-11 2006-06-27 Nephros, Inc. Ionic enhanced dialysis/diafiltration system
WO2001058496A1 (en) * 2000-02-11 2001-08-16 Allied Therapeutics Limited System for the extracorporeal treatment of blood
US8535258B2 (en) * 2000-03-24 2013-09-17 Immunocept, L.L.C. Hemofiltration methods for treatment of diseases in a mammal
US6736972B1 (en) 2000-03-24 2004-05-18 Immunocept, L.L.C. Method and system for providing therapeutic agents with hemofiltration for reducing inflammatory mediator related diseases
US7291122B2 (en) * 2000-03-24 2007-11-06 Immunocept, L.L.C. Hemofiltration methods for treatment of diseases in a mammal
US6602414B2 (en) * 2000-03-30 2003-08-05 Formulations Pro Molecule separation device and method combining multiple filtration media
US6787040B2 (en) * 2000-05-16 2004-09-07 Immunocept, L.L.C. Method and system for colloid exchange therapy
US8597516B2 (en) * 2000-05-16 2013-12-03 Immunocept, L.L.C. Methods and systems for colloid exchange therapy
BR0115183B1 (pt) 2000-10-30 2011-07-26 sistema de diÁlise de sangue, contendo cartucho de hemodiafiltraÇço.
US7241272B2 (en) * 2001-11-13 2007-07-10 Baxter International Inc. Method and composition for removing uremic toxins in dialysis processes
SE522692C2 (sv) * 2002-03-27 2004-03-02 Gambro Lundia Ab Förfarande och anordning för avlägsnande av delvis proteinbundna substanser
US7455771B2 (en) 2002-05-14 2008-11-25 Hepa Wash Gmbh Means for removing protein-bound substances
EP1362605A1 (de) * 2002-05-14 2003-11-19 Bernhard Dr. Kreymann Dialysevorrichtung zur Entfernung proteingebundener Substanzen
WO2004009156A2 (en) 2002-07-19 2004-01-29 Baxter International Inc. Systems and methods for peritoneal dialysis
EP1523347B1 (en) * 2002-07-19 2011-05-18 Baxter International Inc. Systems and methods for performing peritoneal dialysis
WO2004009158A2 (en) * 2002-07-19 2004-01-29 Baxter International Inc. Systems and methods for performing peritoneal dialysis
KR20050083627A (ko) * 2002-08-13 2005-08-26 아비오스 테크놀러지스 인코포레이티드 선택적 혈장 교환 치료
US20040217055A1 (en) * 2003-03-12 2004-11-04 Elmar Kraus Use of recombinant albumin in dialysis after liver failure
US20060076295A1 (en) * 2004-03-15 2006-04-13 The Trustees Of Columbia University In The City Of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
WO2004082796A2 (en) 2003-03-14 2004-09-30 The Trustees Of Columbia University In The City Ofnew York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
DE10324668A1 (de) * 2003-05-30 2004-12-23 Fresenius Medical Care Deutschland Gmbh Vorrichtung zur extrakorporalen Bestrahlung einer Bilirubin enthaltenden Flüssigkeit und Verfahren hierfür
US20050037331A1 (en) * 2003-08-13 2005-02-17 William Galbraith Apparatuses and methods for reducing albumin in samples
US20050045554A1 (en) 2003-08-28 2005-03-03 Gambro Lundia Ab Membrane unit element, semipermeable membrane, filtration device, and processes for manufacturing the same
EP1701752B1 (en) 2003-12-24 2016-05-18 Chemica Technologies, Inc. Dialysate regeneration system for portable human dialysis
JP3980588B2 (ja) * 2004-01-27 2007-09-26 独立行政法人科学技術振興機構 血漿交換廃液浄化循環透析装置
US8038638B2 (en) * 2004-02-23 2011-10-18 Hemolife Medical, Inc. Plasma detoxification and volume control system and methods of use
US7534349B2 (en) * 2005-09-02 2009-05-19 Nephros, Inc. Dual stage ultrafilter devices in the form of portable filter devices, shower devices, and hydration packs
US7775375B2 (en) * 2005-11-03 2010-08-17 Medica S.R.L. Redundant ultrafiltration device
EP1966239A1 (de) * 2005-12-22 2008-09-10 CSL Behring GmbH Oktanoatreduziertes human albumin
CN100457203C (zh) * 2006-01-10 2009-02-04 赵滨宇 血液透析循环装置
JPWO2007086361A1 (ja) * 2006-01-24 2009-06-18 味の素株式会社 アルミニウム蓄積症改善剤
US7727399B2 (en) * 2006-05-22 2010-06-01 The Trustees Of Columbia University In The City Of New York Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams
JP4947693B2 (ja) * 2006-07-14 2012-06-06 学校法人北里研究所 アルブミンとアルブミンに結合した生体分子の分離方法
GB0621452D0 (en) * 2006-10-27 2006-12-06 Ucl Business Plc Therapy for liver disease
ATE477009T1 (de) * 2007-01-12 2010-08-15 Bellco Srl Kit zur behandlung von erkrankungen im zusammenhang mit systemischen entzündungen
DE102007039939B4 (de) 2007-08-23 2013-03-14 Albutec Gmbh Vorrichtung zur Einsparung von Diafiltrat
CA2707582C (en) * 2007-12-03 2014-04-29 Hepa Wash Gmbh Dialysate regeneration unit
MX2010008591A (es) 2008-02-04 2010-08-30 Univ Columbia Dispositivos, sistemas y metodos de separacion de fluidos.
EP2273995B2 (en) * 2008-03-20 2023-11-15 Baxter International Inc. Destruction of microbial products by enzymatic digestion
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
US20100051552A1 (en) 2008-08-28 2010-03-04 Baxter International Inc. In-line sensors for dialysis applications
US8206591B2 (en) 2008-10-16 2012-06-26 Fresenius Medical Care Holdings, Inc. Method of removing protein-bound deleterious substances during extracorporeal renal replacement treatment
EP2380610B1 (en) 2010-04-20 2014-05-07 Gambro Lundia AB High cut-off hemodialysis membrane for use in liver dialysis
EP2452705B1 (en) * 2010-11-10 2015-08-12 Gambro Lundia AB Device for the treatment of blood with selective extraction of solutes
DE102011078700A1 (de) * 2011-07-05 2013-01-10 Charité - Universitätsmedizin Berlin Dialyseverfahren zur Entfernung proteingebundener Toxine aus dem Blut von akut oder chronisch-niereninsuffizienten Patienten
EP2606921A1 (fr) * 2011-12-21 2013-06-26 Infomed SA Dispositif d'épuration du sang par circulation extracorporelle
EP2730303B1 (en) * 2012-11-08 2015-08-12 Gambro Lundia AB Albumin pump control in a MARS treatment apparatus
PL2735360T3 (pl) 2012-11-26 2017-09-29 Gambro Lundia Ab Urządzenie adsorbujące łączące granulki i membrany z włókien kanalikowych
EP2735359B1 (en) 2012-11-26 2017-02-08 Gambro Lundia AB Integrated device for liver support systems
PL2735326T3 (pl) 2012-11-26 2017-08-31 Gambro Lundia Ab Układ wspomagania wątroby
DE102013218239A1 (de) * 2013-08-05 2015-02-19 Tetec Tissue Engineering Technologies Ag Verfahren zur Herstellung eines Produktes mittels Dialyse
EP3102224B1 (en) * 2013-12-20 2019-02-20 NephroGenesis, LLC. Apparatuses for kidney dialysis and lipocalin protein for use in the prevention or treatment of uremia by dialysis
CA2985719C (en) 2015-06-25 2024-03-26 Gambro Lundia Ab Medical device system and method having a distributed database
US9814822B2 (en) * 2015-08-27 2017-11-14 Fresenius Medical Care Holdings, Inc. Plasma generation with dialysis systems
WO2017084683A1 (en) 2015-11-20 2017-05-26 Hepa Wash Gmbh Method for extracorporeal lung support
WO2017084682A1 (en) * 2015-11-20 2017-05-26 Hepa Wash Gmbh Method for extracorporeal carbon dioxide removal
JP6896757B2 (ja) * 2015-12-04 2021-06-30 キドニ ラボズ, インク.Qidni Labs, Inc. 埋込型腎代替療法システム
US11351291B2 (en) 2016-03-14 2022-06-07 Advitos Gmbh Systems or apparatuses and methods for performing dialysis
EP3290067B1 (en) 2016-09-06 2021-03-03 Gambro Lundia AB Liver support system
CN110100283B (zh) 2016-12-21 2023-07-04 甘布罗伦迪亚股份公司 包括具有支持外域的安全集群域的信息技术基础架构的医疗设备系统
KR20200011461A (ko) 2017-05-22 2020-02-03 아드비토스 게엠베하 이산화탄소 제거 방법 및 시스템
US10391220B2 (en) 2018-01-12 2019-08-27 Fresnius Medical Care Holdings, Inc. Virtual kidney donation
US20230036583A1 (en) * 2019-12-31 2023-02-02 Seastar Medical, Inc. Devices and methods for reducing rejection of a transplanted organ in a recipient
US11759556B2 (en) 2020-07-08 2023-09-19 Fresenius Medical Care Holdings, Inc. Parabiotic dialysis systems and techniques

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4375414A (en) * 1971-05-20 1983-03-01 Meir Strahilevitz Immunological methods for removing species from the blood circulatory system and devices therefor
US4163714A (en) * 1975-11-07 1979-08-07 Gregor Harry P Separating substances with pressure-driven affinity sorption membranes
US5078885A (en) * 1983-06-01 1992-01-07 Matsumura Kenneth N Method and apparatus for removing protein-bound molecules from body fluids
US5328614A (en) * 1979-05-21 1994-07-12 Matsumura Kenneth N Methods and apparati for removing protein-bound molecules from body fluids
JPS56115727A (en) * 1980-02-19 1981-09-11 Kuraray Co Ltd Carrier for immobilizing physiologically active substance
US4714556A (en) * 1981-06-29 1987-12-22 Ambrus Clara M Blood purification
DE3230540A1 (de) * 1982-08-17 1984-02-23 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München Verfahren und vorrichtung zur entfernung von protein- oder lipidgebundenen toxinen aus blut oder blutfraktionen
US4741832A (en) * 1984-05-15 1988-05-03 The Trustees Of Columbia, University In The City Of New York Purification apparatus and method employing a regenerable ligand
DE3851572T2 (de) * 1987-06-12 1995-05-24 Kuraray Co Polysulfon-Hohlfasermembran und Verfahren zu ihrer Herstellung.
US5167824A (en) * 1990-02-14 1992-12-01 Creative Biomolecules, Inc. Separation by carrier mediated transport

Also Published As

Publication number Publication date
WO1994021363A1 (en) 1994-09-29
DE69330179T2 (de) 2001-11-08
JPH07506765A (ja) 1995-07-27
JP3486190B2 (ja) 2004-01-13
US5744042A (en) 1998-04-28
EP0615780B1 (en) 2001-04-25
DE69330179D1 (de) 2001-05-31
JP2003299730A (ja) 2003-10-21
DE4309410A1 (de) 1995-02-16
ATE200741T1 (de) 2001-05-15
EP0615780A1 (en) 1994-09-21

Similar Documents

Publication Publication Date Title
ES2157912T3 (es) Membrana y metodo para la separacion de sustancias unidas a proteinas de un liquido que contiene proteinas mediante dialisis.
DE69838147D1 (de) Verbindungen und methoden zur modulierung von occludin-abhängiger gewebepermeabilität
MX170516B (es) Metodo y dispositivo para separar componentes de muestras de liquido.
ES2057377T3 (es) Sistemas de separacion por membranas hibridas.
ES2152990T3 (es) Principios activos y microparticulas que contienen gases.
RO76391A (ro) Membrana multicomponenta pentru separari de gaze
ES2168664T3 (es) Procedimiento para la obtencion de acido acrilico o de acido metacrilico.
CO4910172A1 (es) Sistema de membrana de afinidad y metodo de uso del mismo
ES2130651T3 (es) Lipidos del tipo ceramida modificados con polietilenglicol y liposomas.
DK1181098T4 (da) Patron til udførelse af en kemisk reaktion
AR038568A1 (es) Anticuerpos anti-a beta y su uso
ES2068202T3 (es) Composicion liquida suavizante para prendas de ropa.
FI941242A0 (fi) Kaasumainen ultraäänikontrastiaine ja menetelmä kaasujen valikoimiseksi käytettäviksi ultraäänikontrastiaineina
AR051512A1 (es) Proteina de fusion que comprende un dominio bh3 de una proteina "solo bh3"
ES2115622T3 (es) Clones moleculares de hiv-1 y usos de los mismos.
ES2043181T3 (es) Procedimiento de comprobacion de una membrana de hemodialisis.
HUP0104176A2 (hu) Párologtató- és öntözőberendezés
DE3851367T2 (de) Ammoniaktrennung mittels halbdurchlässiger Membranen.
ATE380202T1 (de) Interaktionssystem zur präsentation und entfernung von substanzen
PL319077A1 (en) Method of and system for extracting dissolved substance from a liquid containing it by means of dense gas and porous membrane
AR212774A1 (es) Mejoras en dispositivos para la difusion de sustancias entre fluidos por medio de membranas semipermeables
DE69101482T2 (de) System für das seitliche Ausrichten von Bögen.
ES2082100T3 (es) Circuito de plasmaferesis extracorporeo de una sola aguja.
DK237678A (da) Organ til taetsluttende anbringelse af semipermeable membraner omkring gennemstroemningsaabningerne i en vaeskeseparator
MX172707B (es) Soluciones absorbentes con diaminoeter y su uso en un proceso para eliminar h2s de corrientes gaseosas

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 615780

Country of ref document: ES