ES2157473T3 - Miembros de union especificos del antigeno carcinoembrionario humano, materiales y procedimientos. - Google Patents

Miembros de union especificos del antigeno carcinoembrionario humano, materiales y procedimientos.

Info

Publication number
ES2157473T3
ES2157473T3 ES96941758T ES96941758T ES2157473T3 ES 2157473 T3 ES2157473 T3 ES 2157473T3 ES 96941758 T ES96941758 T ES 96941758T ES 96941758 T ES96941758 T ES 96941758T ES 2157473 T3 ES2157473 T3 ES 2157473T3
Authority
ES
Spain
Prior art keywords
human
carcinoembryonic antigen
antigen
carcinoembrionary
procedures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96941758T
Other languages
English (en)
Inventor
Jane Katharine Osbourn
Deborah Julie Allen
John Gerald Mccafferty
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MedImmune Ltd
Original Assignee
Cambridge Antibody Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9525004.9A external-priority patent/GB9525004D0/en
Priority claimed from GBGB9610824.6A external-priority patent/GB9610824D0/en
Application filed by Cambridge Antibody Technology Ltd filed Critical Cambridge Antibody Technology Ltd
Application granted granted Critical
Publication of ES2157473T3 publication Critical patent/ES2157473T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)

Abstract

SE PROPORCIONA LA SECUENCIA E INFORMACION RESPECTO A LA UNION DE MIEMBROS DE UNION PARTICULARMENTE VENTAJOSOS QUE SE UNEN AL ANTIGENO CARCINOEMBRIONARIO HUMANO (CEA) CON UNA CONSTANTE DE DISOCIACION MENOR QUE 1,0 X 10 -8 M, NO DAN SUSTANCI ALMENTE REACCION CRUZADA CON CELULAS HEPATICAS HUMANAS, SE UNEN AL DOMINIO EXTRACELULAR A3 - B3 DEL ANTIGENO CARCINOEMBRIONARIO HUMANO Y/O SE UNEN A ANTIGENO CARCINOEMBRIONARIO HUMANO ASOCIADO A CELULAS DE FORMA PREFERENTE SOBRE EL ANTIGENO CARCINOEMBRIONARIO HUMANO SOLUBLE. SON UTILES PARTICULARMENTE EN LA DETERMINACION DE EXPRESION DE CEA POR CELULAS TALES COMO LAS CELULAS TUMORALES.
ES96941758T 1995-12-07 1996-12-09 Miembros de union especificos del antigeno carcinoembrionario humano, materiales y procedimientos. Expired - Lifetime ES2157473T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9525004.9A GB9525004D0 (en) 1995-12-07 1995-12-07 Specific binding members, materials and methods
GBGB9610824.6A GB9610824D0 (en) 1995-12-07 1996-05-23 Specific binding members, materials and methods
GBGB9621295.6A GB9621295D0 (en) 1995-12-07 1996-10-11 Specific binding members,materials and methods

Publications (1)

Publication Number Publication Date
ES2157473T3 true ES2157473T3 (es) 2001-08-16

Family

ID=27268018

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96941758T Expired - Lifetime ES2157473T3 (es) 1995-12-07 1996-12-09 Miembros de union especificos del antigeno carcinoembrionario humano, materiales y procedimientos.

Country Status (10)

Country Link
EP (1) EP0865492B1 (es)
JP (2) JP2000504204A (es)
AT (1) ATE200516T1 (es)
AU (1) AU703319B2 (es)
CA (1) CA2239519C (es)
DE (1) DE69612509T2 (es)
DK (1) DK0865492T3 (es)
ES (1) ES2157473T3 (es)
GB (1) GB9621295D0 (es)
WO (1) WO1997020932A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722131D0 (en) * 1997-10-20 1997-12-17 Medical Res Council Method
SE519405C2 (sv) * 2000-07-19 2003-02-25 Jacob Weitman Tillämpningar för en avancerad digitalkamera som tolkar den tagna bilden utifrån dess informationsinnehåll, såsom att överföra bilden, beordra en tjänst, styra ett flöde mm
WO2003016482A2 (en) 2001-08-17 2003-02-27 Monsanto Technology Llc Methyltransferase genes and uses thereof
GB0130543D0 (en) * 2001-12-20 2002-02-06 Univ Cambridge Tech Human antibodies and their use
WO2003105757A2 (en) * 2002-06-12 2003-12-24 Genencor International, Inc. Methods and compositions for milieu-dependent binding of a targeted agent to a target
GB0309126D0 (en) * 2003-04-17 2003-05-28 Neutec Pharma Plc Clostridium difficile focussed antibodies
CA2547034C (en) * 2003-11-28 2014-02-18 National Research Council Of Canada Anticarcinoma antibodies and uses thereof
PT1691837E (pt) * 2003-12-10 2012-08-27 Medarex Inc Anticorpos ip-10 e suas utilizações
CN101014620B (zh) * 2004-02-06 2012-05-09 马萨诸塞州大学 抗艰难梭菌毒素抗体及其用途
ES2403055T3 (es) 2004-04-13 2013-05-13 F. Hoffmann-La Roche Ag Anticuerpos anti-P-selectina
GB0414886D0 (en) 2004-07-02 2004-08-04 Neutec Pharma Plc Treatment of bacterial infections
AU2006210660B2 (en) 2005-02-01 2011-12-01 Morphosys Ag Libraries and methods for isolating antibodies
US8993715B2 (en) * 2009-07-06 2015-03-31 Canon Kabushiki Kaisha Labeled protein and method for obtaining the same
AU2023237620A1 (en) 2022-03-23 2024-08-29 Synaffix B.V. Antibody-conjugates for targeting of tumours expressing carcinoembyronic antigen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5081235A (en) * 1989-07-26 1992-01-14 City Of Hope Chimeric anti-cea antibody
WO1993011236A1 (en) * 1991-12-02 1993-06-10 Medical Research Council Production of anti-self antibodies from antibody segment repertoires and displayed on phage
GB9317423D0 (en) * 1993-08-21 1993-10-06 Imp Cancer Res Tech Monoclonal antibodies
GB9324807D0 (en) * 1993-12-03 1994-01-19 Cancer Res Campaign Tech Tumour antibody
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination

Also Published As

Publication number Publication date
GB9621295D0 (en) 1996-11-27
AU1103697A (en) 1997-06-27
CA2239519A1 (en) 1997-06-12
EP0865492A1 (en) 1998-09-23
EP0865492B1 (en) 2001-04-11
JP2009148299A (ja) 2009-07-09
WO1997020932A1 (en) 1997-06-12
ATE200516T1 (de) 2001-04-15
DK0865492T3 (da) 2001-06-11
DE69612509D1 (de) 2001-05-17
CA2239519C (en) 2008-09-16
JP2000504204A (ja) 2000-04-11
JP4773540B2 (ja) 2011-09-14
DE69612509T2 (de) 2001-10-18
AU703319B2 (en) 1999-03-25

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