ES2154680T3 - Metodo para controlar el tamaño de los liposomas. - Google Patents
Metodo para controlar el tamaño de los liposomas.Info
- Publication number
- ES2154680T3 ES2154680T3 ES94921494T ES94921494T ES2154680T3 ES 2154680 T3 ES2154680 T3 ES 2154680T3 ES 94921494 T ES94921494 T ES 94921494T ES 94921494 T ES94921494 T ES 94921494T ES 2154680 T3 ES2154680 T3 ES 2154680T3
- Authority
- ES
- Spain
- Prior art keywords
- liposomes
- size
- controlling
- particle size
- mean particle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Abstract
UN PROCESO PARA PRODUCIR UNA POBLACION DE LIPOSOMAS QUE USA UN LIPIDO EN UN SISTEMA SOLVENTE DE FASE UNICA DONDE LOS LIPOSOMAS TIENEN UNA DIMENSION DE PARTICULA MEDIA DESEADA,CONSISTIENDO EL PROCESO EN LA PRUEBA DE LA DIMENSION DE UNA POBLACION DE LIPOSOMAS AÑADIENDO AL LIPIDO UNA CONCENTRACION DE SOLVENTE ELEGIDO PARA FORMAR LA DIMENSION DE PARTICULA MEDIA DESEADA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8874293A | 1993-07-08 | 1993-07-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2154680T3 true ES2154680T3 (es) | 2001-04-16 |
Family
ID=22213183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94921494T Expired - Lifetime ES2154680T3 (es) | 1993-07-08 | 1994-07-08 | Metodo para controlar el tamaño de los liposomas. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6596305B1 (es) |
EP (1) | EP0707472B1 (es) |
JP (1) | JP3479535B2 (es) |
AT (1) | ATE199640T1 (es) |
CA (1) | CA2166465C (es) |
DE (1) | DE69426884T2 (es) |
DK (1) | DK0707472T3 (es) |
ES (1) | ES2154680T3 (es) |
GR (1) | GR3035825T3 (es) |
PT (1) | PT707472E (es) |
WO (1) | WO1995001777A1 (es) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6001333A (en) * | 1997-09-12 | 1999-12-14 | See; Jackie R. | Methods of preparing micro encapsulated agents for use in the detection of tumors by CT imaging |
IL144756A0 (en) * | 1999-02-08 | 2002-06-30 | Alza Corp | Method for controlling liposome size |
US6613352B2 (en) | 1999-04-13 | 2003-09-02 | Universite De Montreal | Low-rigidity liposomal formulation |
NZ534142A (en) * | 2002-01-21 | 2007-08-31 | Vasogen Ireland Ltd | Pharmaceutically acceptable phosphate-glycerol carrying bodies comprising phospatidylglycerol and/or phosphatidylcholine and/or phosphatidylglycerol |
AU2003225689B2 (en) * | 2002-03-05 | 2009-03-26 | Transave, Inc. | Methods for entrapment of bioactive agent in a liposome or lipid complex |
ATE485031T1 (de) | 2002-06-28 | 2010-11-15 | Protiva Biotherapeutics Inc | Verfahren und vorrichtung zur herstellung von liposomen |
US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
US9198645B2 (en) * | 2003-11-26 | 2015-12-01 | The United States of America, as represented by the Secretary of Commerce of The National Institute of Standards and Technology | Controlled vesicle self-assembly in continuous two phase flow microfluidic channels |
US20050129750A1 (en) * | 2003-12-15 | 2005-06-16 | Yu-Fang Hu | Process for producing liposome suspension and product containing liposome suspension produced thereby |
US8784881B2 (en) * | 2004-03-05 | 2014-07-22 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of diseases |
US8715591B2 (en) * | 2004-07-21 | 2014-05-06 | The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology | Microfluidic apparatus to control liposome formation |
AU2006274413B2 (en) * | 2005-07-27 | 2013-01-10 | Arbutus Biopharma Corporation | Systems and methods for manufacturing liposomes |
JP2009519250A (ja) * | 2005-12-08 | 2009-05-14 | ワイス | リポソーム組成物 |
EP3067046B1 (en) | 2005-12-08 | 2020-03-25 | Insmed Incorporated | Lipid-based compositions of antiinfectives for treating pulmonary infections |
EP2012750B1 (en) * | 2006-04-06 | 2018-02-21 | Insmed Incorporated | Methods for coacervation induced liposomal encapsulation and formulations thereof |
US20080268031A1 (en) * | 2007-03-15 | 2008-10-30 | Benjamin Johnson | Therapeutic Treatment of Dermatologic Skin Disorders |
EP2146692A1 (en) * | 2007-03-19 | 2010-01-27 | Fresenius Kabi Oncology Limited | Proliposomal and liposomal compositions |
US20100196455A1 (en) | 2007-05-04 | 2010-08-05 | Transave, Inc. | Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof |
US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
US20110105995A1 (en) * | 2008-01-16 | 2011-05-05 | Zhu Ting F | Uniform-sized, multi-drug carrying, and photosensitive liposomes for advanced drug delivery |
US20090246234A1 (en) * | 2008-04-01 | 2009-10-01 | Benjamin Johnson | Therapeutic Treatment Using Niacin for Skin Disorders |
US8911711B2 (en) * | 2008-09-30 | 2014-12-16 | The Invention Science Fund I, Llc | Method, device, and system to control pH in pulmonary tissue of a subject |
WO2010135714A2 (en) | 2009-05-22 | 2010-11-25 | The Methodist Hospital Research Institute | Methods for modulating adipocyte expression using microrna compositions |
TWI410256B (zh) * | 2010-01-07 | 2013-10-01 | Nat Univ Tsing Hua | 雙重乳化法製備微脂體之新型裝置 |
AU2011353698B2 (en) * | 2011-01-05 | 2017-05-11 | Livon Laboratories | Methods of making liposomes, liposome compositions made by the methods, and methods of using the same |
US8642655B2 (en) | 2011-03-09 | 2014-02-04 | Benjamin Johnson | Systems and methods for preventing cancer and treating skin lesions |
GB201116248D0 (en) * | 2011-09-20 | 2011-11-02 | Glaxosmithkline Biolog Sa | Liposome production using isopropanol |
CA2871821C (en) * | 2012-05-10 | 2021-01-12 | Painreform Ltd. | Depot formulations of a local anesthetic and methods for preparation thereof |
SI2852391T1 (sl) | 2012-05-21 | 2022-04-29 | Insmed Incorporated | Sistemi za obravnavo pljučnih infekcij |
US20140120157A1 (en) | 2012-09-19 | 2014-05-01 | Georgetown University | Targeted liposomes |
CA2891487A1 (en) | 2012-11-29 | 2014-06-05 | Insmed Incorporated | Stabilized vancomycin formulations |
DK3466432T3 (da) | 2014-05-15 | 2020-09-28 | Insmed Inc | Fremgangsmåder til behandling af pulmonale non-tuberkuløse mykobakterielle infektioner |
CN106568831B (zh) * | 2016-11-18 | 2019-07-23 | 武汉理工大学 | 一种用于检测磷酸肌醇的多孔膜材料及其制备与检测方法 |
CN110996911B (zh) * | 2017-06-26 | 2023-01-17 | 福多兹制药公司 | 阿瑞匹坦的纳米微脂囊配制品及其方法和应用 |
WO2019028186A1 (en) * | 2017-08-01 | 2019-02-07 | Ankasa Regenerative Therapeutics, Inc. | WNT COMPOSITIONS AND METHODS OF TREATMENT FROM SERUM-FREE CULTURE CONDITIONS |
WO2019088193A1 (ja) * | 2017-11-01 | 2019-05-09 | 国立大学法人大阪大学 | 所望の粒径を有する脂質粒子を製造するための方法および装置の開発 |
US11344497B1 (en) | 2017-12-08 | 2022-05-31 | Quicksilver Scientific, Inc. | Mitochondrial performance enhancement nanoemulsion |
US10722465B1 (en) | 2017-12-08 | 2020-07-28 | Quicksilber Scientific, Inc. | Transparent colloidal vitamin supplement |
WO2019191627A1 (en) | 2018-03-30 | 2019-10-03 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
US11291702B1 (en) | 2019-04-15 | 2022-04-05 | Quicksilver Scientific, Inc. | Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4039285A (en) * | 1975-10-10 | 1977-08-02 | Ortho Diagnostics, Inc. | Single sample method for determination of lipoprotein concentrations in blood |
US4184849A (en) * | 1977-12-05 | 1980-01-22 | Technicon Instruments Corporation | Mixed agglutination |
US4529561A (en) | 1978-03-24 | 1985-07-16 | The Regents Of The University Of California | Method for producing liposomes in selected size range |
US4522803A (en) | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
US4588578A (en) | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
CA1237670A (en) | 1983-05-26 | 1988-06-07 | Andrew S. Janoff | Drug preparations of reduced toxicity |
EP0158441B2 (en) * | 1984-03-08 | 2001-04-04 | Phares Pharmaceutical Research N.V. | Liposome-forming composition |
US4721612A (en) | 1984-04-12 | 1988-01-26 | The Liposome Company, Inc. | Steroidal liposomes |
US4619895A (en) * | 1984-05-10 | 1986-10-28 | The Regents Of The University Of California | Lipoprotein marker for hypertriglyceridemia |
US5008050A (en) | 1984-06-20 | 1991-04-16 | The Liposome Company, Inc. | Extrusion technique for producing unilamellar vesicles |
US5077056A (en) | 1984-08-08 | 1991-12-31 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
GB8426264D0 (en) | 1984-10-17 | 1984-11-21 | Alcan Int Ltd | Porous films |
US4861580A (en) | 1985-10-15 | 1989-08-29 | The Liposome Company, Inc. | Composition using salt form of organic acid derivative of alpha-tocopheral |
US4737323A (en) | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
US5154930A (en) | 1987-03-05 | 1992-10-13 | The Liposome Company, Inc. | Pharmacological agent-lipid solution preparation |
US5082664A (en) | 1987-05-22 | 1992-01-21 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
ATE113468T1 (de) | 1987-07-29 | 1994-11-15 | Liposome Co Inc | Verfahren zur trennung von teilchen nach grösse. |
US5000887A (en) * | 1988-05-17 | 1991-03-19 | Liposome Technology, Inc. | Preparation of uniform-size liposomes |
AU3564589A (en) | 1988-05-17 | 1989-12-12 | Liposome Technology, Inc. | Preparation of uniform-size liposomes and other lipid structures |
US4994213A (en) * | 1988-05-17 | 1991-02-19 | Liposome Technology, Inc. | Method of preparing lipid structures |
US4927637A (en) | 1989-01-17 | 1990-05-22 | Liposome Technology, Inc. | Liposome extrusion method |
AU638245B2 (en) | 1989-03-31 | 1993-06-24 | Regents Of The University Of California, The | Preparation of liposome and lipid complex compositions |
-
1994
- 1994-07-08 PT PT94921494T patent/PT707472E/pt unknown
- 1994-07-08 JP JP50418595A patent/JP3479535B2/ja not_active Expired - Fee Related
- 1994-07-08 ES ES94921494T patent/ES2154680T3/es not_active Expired - Lifetime
- 1994-07-08 DE DE69426884T patent/DE69426884T2/de not_active Expired - Fee Related
- 1994-07-08 WO PCT/US1994/007683 patent/WO1995001777A1/en active IP Right Grant
- 1994-07-08 EP EP94921494A patent/EP0707472B1/en not_active Expired - Lifetime
- 1994-07-08 AT AT94921494T patent/ATE199640T1/de not_active IP Right Cessation
- 1994-07-08 DK DK94921494T patent/DK0707472T3/da active
- 1994-07-08 CA CA002166465A patent/CA2166465C/en not_active Expired - Fee Related
-
1995
- 1995-05-16 US US08/442,077 patent/US6596305B1/en not_active Expired - Fee Related
-
2001
- 2001-04-30 GR GR20010400673T patent/GR3035825T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US6596305B1 (en) | 2003-07-22 |
EP0707472A1 (en) | 1996-04-24 |
EP0707472B1 (en) | 2001-03-14 |
WO1995001777A1 (en) | 1995-01-19 |
GR3035825T3 (en) | 2001-07-31 |
DK0707472T3 (da) | 2001-04-17 |
DE69426884D1 (de) | 2001-04-19 |
JP3479535B2 (ja) | 2003-12-15 |
PT707472E (pt) | 2001-07-31 |
DE69426884T2 (de) | 2001-06-21 |
ATE199640T1 (de) | 2001-03-15 |
CA2166465C (en) | 2003-10-14 |
CA2166465A1 (en) | 1995-01-19 |
JPH08512240A (ja) | 1996-12-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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