ES2154680T3 - Metodo para controlar el tamaño de los liposomas. - Google Patents
Metodo para controlar el tamaño de los liposomas.Info
- Publication number
- ES2154680T3 ES2154680T3 ES94921494T ES94921494T ES2154680T3 ES 2154680 T3 ES2154680 T3 ES 2154680T3 ES 94921494 T ES94921494 T ES 94921494T ES 94921494 T ES94921494 T ES 94921494T ES 2154680 T3 ES2154680 T3 ES 2154680T3
- Authority
- ES
- Spain
- Prior art keywords
- liposomes
- size
- controlling
- particle size
- mean particle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
UN PROCESO PARA PRODUCIR UNA POBLACION DE LIPOSOMAS QUE USA UN LIPIDO EN UN SISTEMA SOLVENTE DE FASE UNICA DONDE LOS LIPOSOMAS TIENEN UNA DIMENSION DE PARTICULA MEDIA DESEADA,CONSISTIENDO EL PROCESO EN LA PRUEBA DE LA DIMENSION DE UNA POBLACION DE LIPOSOMAS AÑADIENDO AL LIPIDO UNA CONCENTRACION DE SOLVENTE ELEGIDO PARA FORMAR LA DIMENSION DE PARTICULA MEDIA DESEADA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8874293A | 1993-07-08 | 1993-07-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2154680T3 true ES2154680T3 (es) | 2001-04-16 |
Family
ID=22213183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94921494T Expired - Lifetime ES2154680T3 (es) | 1993-07-08 | 1994-07-08 | Metodo para controlar el tamaño de los liposomas. |
Country Status (11)
Country | Link |
---|---|
US (1) | US6596305B1 (es) |
EP (1) | EP0707472B1 (es) |
JP (1) | JP3479535B2 (es) |
AT (1) | ATE199640T1 (es) |
CA (1) | CA2166465C (es) |
DE (1) | DE69426884T2 (es) |
DK (1) | DK0707472T3 (es) |
ES (1) | ES2154680T3 (es) |
GR (1) | GR3035825T3 (es) |
PT (1) | PT707472E (es) |
WO (1) | WO1995001777A1 (es) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6001333A (en) * | 1997-09-12 | 1999-12-14 | See; Jackie R. | Methods of preparing micro encapsulated agents for use in the detection of tumors by CT imaging |
ATE272392T1 (de) * | 1999-02-08 | 2004-08-15 | Alza Corp | Verfahren zur kontrolle der liposomengrösse |
US6613352B2 (en) | 1999-04-13 | 2003-09-02 | Universite De Montreal | Low-rigidity liposomal formulation |
AU2003201569B2 (en) * | 2002-01-21 | 2008-09-11 | Vasogen Ireland Limited | Pharmaceutically acceptable phosphate-glycerol carrying bodies |
AU2003230600B2 (en) * | 2002-03-05 | 2009-06-04 | Transave, Inc. | An inhalation system for prevention and treatment of intracellular infections |
DE60334618D1 (de) | 2002-06-28 | 2010-12-02 | Protiva Biotherapeutics Inc | Verfahren und vorrichtung zur herstellung von liposomen |
US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
US9198645B2 (en) * | 2003-11-26 | 2015-12-01 | The United States of America, as represented by the Secretary of Commerce of The National Institute of Standards and Technology | Controlled vesicle self-assembly in continuous two phase flow microfluidic channels |
US20050129750A1 (en) * | 2003-12-15 | 2005-06-16 | Yu-Fang Hu | Process for producing liposome suspension and product containing liposome suspension produced thereby |
US8784881B2 (en) * | 2004-03-05 | 2014-07-22 | Board Of Regents, The University Of Texas System | Liposomal curcumin for treatment of diseases |
US8715591B2 (en) * | 2004-07-21 | 2014-05-06 | The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology | Microfluidic apparatus to control liposome formation |
CN103989633A (zh) * | 2005-07-27 | 2014-08-20 | 普洛体维生物治疗公司 | 制造脂质体的系统和方法 |
CN101325947A (zh) * | 2005-12-08 | 2008-12-17 | 惠氏公司 | 脂质体组合物 |
HUE029994T2 (en) | 2005-12-08 | 2017-04-28 | Insmed Inc | Lipid-based preparations of antinfectants for the treatment of lung infections |
US20080089927A1 (en) * | 2006-04-06 | 2008-04-17 | Vladimir Malinin | Methods for Coacervation Induced Liposomal Encapsulation and Formulations Thereof |
US20080268031A1 (en) * | 2007-03-15 | 2008-10-30 | Benjamin Johnson | Therapeutic Treatment of Dermatologic Skin Disorders |
EP2146692A1 (en) * | 2007-03-19 | 2010-01-27 | Fresenius Kabi Oncology Limited | Proliposomal and liposomal compositions |
US20100196455A1 (en) * | 2007-05-04 | 2010-08-05 | Transave, Inc. | Compositions of Multicationic Drugs for Reducing Interactions with Polyanionic Biomolecules and Methods of Use Thereof |
US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
US20110105995A1 (en) * | 2008-01-16 | 2011-05-05 | Zhu Ting F | Uniform-sized, multi-drug carrying, and photosensitive liposomes for advanced drug delivery |
US20090246234A1 (en) * | 2008-04-01 | 2009-10-01 | Benjamin Johnson | Therapeutic Treatment Using Niacin for Skin Disorders |
US20100081954A1 (en) * | 2008-09-30 | 2010-04-01 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method, device, and system to control pH in pulmonary tissue of a subject |
WO2010135714A2 (en) | 2009-05-22 | 2010-11-25 | The Methodist Hospital Research Institute | Methods for modulating adipocyte expression using microrna compositions |
TWI410256B (zh) * | 2010-01-07 | 2013-10-01 | Nat Univ Tsing Hua | 雙重乳化法製備微脂體之新型裝置 |
US10016389B2 (en) * | 2011-01-05 | 2018-07-10 | Livon Laboratories | Method of making liposomes, liposome compositions made by the methods, and methods of using the same |
US8642655B2 (en) | 2011-03-09 | 2014-02-04 | Benjamin Johnson | Systems and methods for preventing cancer and treating skin lesions |
GB201116248D0 (en) * | 2011-09-20 | 2011-11-02 | Glaxosmithkline Biolog Sa | Liposome production using isopropanol |
WO2013168167A1 (en) * | 2012-05-10 | 2013-11-14 | Painreform Ltd. | Depot formulations of a hydrophobic active ingredient and methods for preparation thereof |
US20150272880A1 (en) | 2012-05-21 | 2015-10-01 | Insmed Incorporated | Systems for treating pulmonary infections |
US20140120157A1 (en) | 2012-09-19 | 2014-05-01 | Georgetown University | Targeted liposomes |
BR112015012351A8 (pt) | 2012-11-29 | 2019-10-01 | Insmed Inc | composição de antibiótico de glicopeptídeo à base de lipídeo estabilizado e uso de um componente lipídico, um componente de antibiótico de glicopeptídeo e um aminoácido ou derivado do mesmo |
PL3142643T3 (pl) | 2014-05-15 | 2019-12-31 | Insmed Incorporated | Sposoby leczenia zakażeń płuc prątkami niegruźliczymi |
CN106568831B (zh) * | 2016-11-18 | 2019-07-23 | 武汉理工大学 | 一种用于检测磷酸肌醇的多孔膜材料及其制备与检测方法 |
US11260028B2 (en) * | 2017-06-26 | 2022-03-01 | Fordoz Pharma Corp. | Nanosome formulations of aprepitant and methods and applications thereof |
GB2581882B (en) * | 2017-08-01 | 2023-03-29 | Ankasa Regenerative Therapeutics Inc | WNT compositions and methods of process from serum-free culturing conditions |
CN111565833B (zh) * | 2017-11-01 | 2023-04-07 | 国立大学法人大阪大学 | 用于制造具有期望的粒径的脂质颗粒的方法及装置的开发 |
US11344497B1 (en) | 2017-12-08 | 2022-05-31 | Quicksilver Scientific, Inc. | Mitochondrial performance enhancement nanoemulsion |
US10722465B1 (en) | 2017-12-08 | 2020-07-28 | Quicksilber Scientific, Inc. | Transparent colloidal vitamin supplement |
JP7460534B2 (ja) | 2018-03-30 | 2024-04-02 | インスメッド インコーポレイテッド | リポソーム医薬品の連続製造方法 |
US11291702B1 (en) | 2019-04-15 | 2022-04-05 | Quicksilver Scientific, Inc. | Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4039285A (en) * | 1975-10-10 | 1977-08-02 | Ortho Diagnostics, Inc. | Single sample method for determination of lipoprotein concentrations in blood |
US4184849A (en) * | 1977-12-05 | 1980-01-22 | Technicon Instruments Corporation | Mixed agglutination |
US4529561A (en) | 1978-03-24 | 1985-07-16 | The Regents Of The University Of California | Method for producing liposomes in selected size range |
US4522803A (en) | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
US4588578A (en) | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
CA1237670A (en) | 1983-05-26 | 1988-06-07 | Andrew S. Janoff | Drug preparations of reduced toxicity |
JPH0753661B2 (ja) * | 1984-03-08 | 1995-06-07 | フアレス フアーマスーチカル リサーチ エヌブイ | プロ―リポソーム組成物及びリポソームの水性分散物を作る方法 |
US4721612A (en) | 1984-04-12 | 1988-01-26 | The Liposome Company, Inc. | Steroidal liposomes |
US4619895A (en) * | 1984-05-10 | 1986-10-28 | The Regents Of The University Of California | Lipoprotein marker for hypertriglyceridemia |
US5008050A (en) | 1984-06-20 | 1991-04-16 | The Liposome Company, Inc. | Extrusion technique for producing unilamellar vesicles |
US5077056A (en) | 1984-08-08 | 1991-12-31 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
GB8426264D0 (en) | 1984-10-17 | 1984-11-21 | Alcan Int Ltd | Porous films |
US4861580A (en) | 1985-10-15 | 1989-08-29 | The Liposome Company, Inc. | Composition using salt form of organic acid derivative of alpha-tocopheral |
US4737323A (en) | 1986-02-13 | 1988-04-12 | Liposome Technology, Inc. | Liposome extrusion method |
US5154930A (en) | 1987-03-05 | 1992-10-13 | The Liposome Company, Inc. | Pharmacological agent-lipid solution preparation |
US5082664A (en) | 1987-05-22 | 1992-01-21 | The Liposome Company, Inc. | Prostaglandin-lipid formulations |
DE3852037T2 (de) | 1987-07-29 | 1995-03-23 | Liposome Co Inc | Verfahren zur trennung von teilchen nach grösse. |
AU3564589A (en) | 1988-05-17 | 1989-12-12 | Liposome Technology, Inc. | Preparation of uniform-size liposomes and other lipid structures |
US4994213A (en) * | 1988-05-17 | 1991-02-19 | Liposome Technology, Inc. | Method of preparing lipid structures |
US5000887A (en) * | 1988-05-17 | 1991-03-19 | Liposome Technology, Inc. | Preparation of uniform-size liposomes |
US4927637A (en) | 1989-01-17 | 1990-05-22 | Liposome Technology, Inc. | Liposome extrusion method |
WO1990011780A1 (en) | 1989-03-31 | 1990-10-18 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
-
1994
- 1994-07-08 AT AT94921494T patent/ATE199640T1/de not_active IP Right Cessation
- 1994-07-08 EP EP94921494A patent/EP0707472B1/en not_active Expired - Lifetime
- 1994-07-08 CA CA002166465A patent/CA2166465C/en not_active Expired - Fee Related
- 1994-07-08 ES ES94921494T patent/ES2154680T3/es not_active Expired - Lifetime
- 1994-07-08 DK DK94921494T patent/DK0707472T3/da active
- 1994-07-08 DE DE69426884T patent/DE69426884T2/de not_active Expired - Fee Related
- 1994-07-08 JP JP50418595A patent/JP3479535B2/ja not_active Expired - Fee Related
- 1994-07-08 PT PT94921494T patent/PT707472E/pt unknown
- 1994-07-08 WO PCT/US1994/007683 patent/WO1995001777A1/en active IP Right Grant
-
1995
- 1995-05-16 US US08/442,077 patent/US6596305B1/en not_active Expired - Fee Related
-
2001
- 2001-04-30 GR GR20010400673T patent/GR3035825T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH08512240A (ja) | 1996-12-24 |
CA2166465A1 (en) | 1995-01-19 |
WO1995001777A1 (en) | 1995-01-19 |
DE69426884T2 (de) | 2001-06-21 |
PT707472E (pt) | 2001-07-31 |
DE69426884D1 (de) | 2001-04-19 |
EP0707472A1 (en) | 1996-04-24 |
JP3479535B2 (ja) | 2003-12-15 |
US6596305B1 (en) | 2003-07-22 |
GR3035825T3 (en) | 2001-07-31 |
EP0707472B1 (en) | 2001-03-14 |
DK0707472T3 (da) | 2001-04-17 |
CA2166465C (en) | 2003-10-14 |
ATE199640T1 (de) | 2001-03-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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