ES2153457T3 - Amino-alquil-benzoxazolinonas y benzotiazolinonas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen. - Google Patents

Amino-alquil-benzoxazolinonas y benzotiazolinonas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.

Info

Publication number
ES2153457T3
ES2153457T3 ES95400613T ES95400613T ES2153457T3 ES 2153457 T3 ES2153457 T3 ES 2153457T3 ES 95400613 T ES95400613 T ES 95400613T ES 95400613 T ES95400613 T ES 95400613T ES 2153457 T3 ES2153457 T3 ES 2153457T3
Authority
ES
Spain
Prior art keywords
alkyl
benzoxazolinonas
benzotiazolinonas
alquil
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95400613T
Other languages
English (en)
Inventor
Ange Mouithys-Mickalad
Patrick Depreux
Daniel Lesieur
Gerard Adam
Daniel-Henri Caignard
Pierre Renard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of ES2153457T3 publication Critical patent/ES2153457T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

LA INVENCION SE REFIERE A LOS COMPUESTOS DE FORMULA (I): EN LA QUE R1, R2, R3, X Y N SON TALES COMO SE DEFINEN EN LA DESCRIPCION, SUS ISOMEROS OPTICOS, Y SUS SALES DE ADICION A UN ACIDO O UNA BASE FARMACEUTICAMENTE ACEPTABLE. MEDICAMENTOS.
ES95400613T 1994-03-22 1995-03-21 Amino-alquil-benzoxazolinonas y benzotiazolinonas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen. Expired - Lifetime ES2153457T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9403298A FR2717810B1 (fr) 1994-03-22 1994-03-22 Nouvelles aminoalkyl benzoxazolinones et benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ES2153457T3 true ES2153457T3 (es) 2001-03-01

Family

ID=9461264

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95400613T Expired - Lifetime ES2153457T3 (es) 1994-03-22 1995-03-21 Amino-alquil-benzoxazolinonas y benzotiazolinonas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.

Country Status (17)

Country Link
US (3) US5534511A (es)
EP (1) EP0673933B1 (es)
JP (1) JP2705788B2 (es)
CN (1) CN1055924C (es)
AT (1) ATE197450T1 (es)
AU (1) AU680717B2 (es)
CA (1) CA2145026A1 (es)
DE (1) DE69519315T2 (es)
DK (1) DK0673933T3 (es)
ES (1) ES2153457T3 (es)
FI (1) FI951297A (es)
FR (1) FR2717810B1 (es)
GR (1) GR3035175T3 (es)
NO (1) NO304689B1 (es)
NZ (1) NZ270760A (es)
PT (1) PT673933E (es)
ZA (1) ZA952333B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2717810B1 (fr) * 1994-03-22 1996-04-26 Adir Nouvelles aminoalkyl benzoxazolinones et benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
WO1997004593A1 (en) * 1995-07-19 1997-02-06 Kabushiki Kaisha Toshiba Letter box converter
ZA9610745B (en) * 1995-12-22 1997-06-24 Warner Lambert Co 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists
FR2755690B1 (fr) * 1996-11-08 1998-12-18 Adir Nouveaux derives aminomethyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
NZ502785A (en) * 1997-10-24 2003-03-28 Warner Lambert Co Use of NR1A/2B site-selective NMDA receptor antagonist compounds for treating disease-related or drug-induced dyskinesias
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
DE19812331A1 (de) * 1998-03-20 1999-09-23 Merck Patent Gmbh Piperidinderivate
US7794761B2 (en) * 2000-04-13 2010-09-14 Seroctin Research & Technology, Inc. Methods for inducing anti-anxiety and calming effects in animals and humans
US20040192669A1 (en) * 2000-04-13 2004-09-30 Rosenfeld Mark J. Novel compounds for use in weight loss and appetite suppression in humans
US7524877B2 (en) 2003-11-20 2009-04-28 Seroctin Research & Technology, Inc. Compounds for use in weight loss and appetite suppression in humans
ATE440826T1 (de) 2004-05-27 2009-09-15 Ucb Pharma Sa Benzoxazolonderivate, verfahren zu deren herstellung und deren anwendungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2536749A1 (fr) * 1982-11-25 1984-06-01 Cerm Cent Europ Rech Mauvernay (amino-2 ethyl)-6 benzoxazolinones substituees, leur preparation et leurs applications en therapeutique
US4554284A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
FR2643634A1 (fr) * 1989-02-28 1990-08-31 Adir Nouveaux derives benzoxazolinoniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2667068B1 (fr) * 1990-09-26 1994-09-09 Adir Nouvelles amines alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2674524B1 (fr) * 1991-03-25 1993-05-21 Adir Nouveaux amides alkyl heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2717810B1 (fr) * 1994-03-22 1996-04-26 Adir Nouvelles aminoalkyl benzoxazolinones et benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
AU680717B2 (en) 1997-08-07
FI951297A0 (fi) 1995-03-20
FI951297A (fi) 1995-09-23
EP0673933A1 (fr) 1995-09-27
NO951081D0 (no) 1995-03-21
DK0673933T3 (da) 2001-01-02
DE69519315D1 (de) 2000-12-14
US5688820A (en) 1997-11-18
JPH07258233A (ja) 1995-10-09
AU1498895A (en) 1995-09-28
PT673933E (pt) 2001-02-28
GR3035175T3 (en) 2001-04-30
ZA952333B (en) 1995-12-15
US5534511A (en) 1996-07-09
JP2705788B2 (ja) 1998-01-28
NZ270760A (en) 1996-03-26
EP0673933B1 (fr) 2000-11-08
NO951081L (no) 1995-09-25
NO304689B1 (no) 1999-02-01
ATE197450T1 (de) 2000-11-11
US5688811A (en) 1997-11-18
FR2717810A1 (fr) 1995-09-29
FR2717810B1 (fr) 1996-04-26
CA2145026A1 (fr) 1995-09-23
DE69519315T2 (de) 2001-05-31
CN1112114A (zh) 1995-11-22
CN1055924C (zh) 2000-08-30

Similar Documents

Publication Publication Date Title
FI922141A (fi) Analogiamenetelmä uusien hypoglykeemisten oksatsolidiinidionien valmistamiseksi
ES2097583T3 (es) Procedimiento de preparacion de derivados de alcoxiiminoacetamida y un intermediario de este procedimiento.
DE2966163D1 (en) Process for the preparation of phosphorus-containing cyanhydrine derivatives and those cyanhydrine derivatives
ES2153457T3 (es) Amino-alquil-benzoxazolinonas y benzotiazolinonas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.
PT83725B (pt) Processo para preparacao de novos derivados da 3-oxadiol-beta-carbolina e 3-carboxilato-beta-carbolina e de composicoes farmaceuticas que os contem
EP0224163A3 (en) Propyl amines, process for their preparation and their use as fungicides
AR241136A2 (es) Procedimiento para preparar esteres de 6-hidroxi-2-benzotiazolsulfonamida para tratamiento topicode presion intraocular elevada"
BR8004488A (pt) Processo para a preparacao de derivados de triazolil-alcenois,composicao fungicida e sua aplicacao
FR2455039B1 (es)
DK351886D0 (da) 4-oh-quinolincarboxylsyrederivater, deres fremstilling, mellemprodukter ved deres fremstilling samt laegemidler med indhold deraf
DE69213656T2 (de) 1-Alkyl-2-Acyl-1,2-Disulfonylhydrazine mit antineoplastischer Aktivität
FI952203A (fi) Sykloheksaanijohdannaiset, menetelmä niiden valmistamiseksi ja yhdisteiden käyttö sairauksien hoitamiseksi
SE8406046D0 (sv) New azabiocyclic compounds and a process for the preparation thereof
DE59606328D1 (de) Verfahren zur Herstellung von gegebenenfalls 2-substituierten 5-Chlor-imidazol-4-carbaldehyden
ES2158055T3 (es) Nuevas amino-alquil-benzotiazolinonas, su procedimiento de preparacio n y las composiciones farmaceuticas que las contienen.
DK27081A (da) Indan-4-yl-n-alkyl-carbaminsyreestere,fremgangsmaade til fremstilling heraf samt deres anvendelse som fungicider
FR2557875B1 (fr) Aminoethylimidazole, composition pharmaceutique en contenant et procede de preparation
ATE1585T1 (de) Clavulansaeurederivate, ihre herstellung und sie enthaltende pharmazeutische praeparate.
DE3266678D1 (en) Substituted phenylcyclopropanecarboxylic-acid esters, process for their preparation and their use as insecticides
ES8301906A1 (es) Un procedimiento para la preparacion de un derivado de sul- fonamida

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 673933

Country of ref document: ES