ES2152459T3 - Aminopiranos sustituidos con acilo con actividad moduladora sobre canales de potasio. - Google Patents

Aminopiranos sustituidos con acilo con actividad moduladora sobre canales de potasio.

Info

Publication number
ES2152459T3
ES2152459T3 ES96112426T ES96112426T ES2152459T3 ES 2152459 T3 ES2152459 T3 ES 2152459T3 ES 96112426 T ES96112426 T ES 96112426T ES 96112426 T ES96112426 T ES 96112426T ES 2152459 T3 ES2152459 T3 ES 2152459T3
Authority
ES
Spain
Prior art keywords
pyran
acetyl
amino
alkyl
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96112426T
Other languages
English (en)
Inventor
Klaus Dr Urbahns
Hans-Georg Dr Heine
Bodo Dr Junge
Frank Dr Mauler
Reilinde Dr Wittka
Vry Jean-Marie-Viktor Dr De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2152459T3 publication Critical patent/ES2152459T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

LA INVENCION TRATA DE LA UTILIZACION DE AMINO-PIRANOS SUSTITUIDOS CON ACILO DE FORMULA (I) PARA LA OBTENCION DE MEDICAMENTOS, EN ESPECIAL DE MEDICAMENTOS PARA EL TRATAMIENTO DE ENFERMEDADES DEL SISTEMA NERVIOSO CENTRAL. A, R{SUP,1}-R{SUP,5} TIENEN LOS SIGNIFICADOS DADOS EN LA DESCRIPCION.
ES96112426T 1995-08-14 1996-08-01 Aminopiranos sustituidos con acilo con actividad moduladora sobre canales de potasio. Expired - Lifetime ES2152459T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19529859A DE19529859A1 (de) 1995-08-14 1995-08-14 Verwendung von Acyl-substituierten Aminopyranen

Publications (1)

Publication Number Publication Date
ES2152459T3 true ES2152459T3 (es) 2001-02-01

Family

ID=7769443

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96112426T Expired - Lifetime ES2152459T3 (es) 1995-08-14 1996-08-01 Aminopiranos sustituidos con acilo con actividad moduladora sobre canales de potasio.

Country Status (10)

Country Link
US (1) US5719181A (es)
EP (1) EP0758647B1 (es)
JP (1) JPH0959270A (es)
AT (1) ATE197298T1 (es)
CA (1) CA2183052A1 (es)
DE (2) DE19529859A1 (es)
DK (1) DK0758647T3 (es)
ES (1) ES2152459T3 (es)
GR (1) GR3035097T3 (es)
PT (1) PT758647E (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11306066B2 (en) 2015-05-08 2022-04-19 Monash University 4H-pyran compounds as insulin-regulated aminopeptidase (IRAP) inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2235406C3 (de) * 1972-07-19 1982-01-07 Bayer Ag, 5090 Leverkusen 2-Amino-4H-pyrane, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
US3966767A (en) * 1972-07-19 1976-06-29 Bayer Aktiengesellschaft 2-Amino-4 H-pyrane
US3974290A (en) * 1972-07-19 1976-08-10 Bayer Aktiengesellschaft Vasodilating and antihypertensive compositions and methods of effecting vasodilation and treating hypertension utilizing 2-amino-4H pyrane as the active agent
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE4429786A1 (de) * 1994-08-23 1996-02-29 Bayer Ag Verwendung von substituierten 6-Amino-4H-pyranen

Also Published As

Publication number Publication date
ATE197298T1 (de) 2000-11-15
CA2183052A1 (en) 1997-02-15
DE59606077D1 (de) 2000-12-07
EP0758647A1 (de) 1997-02-19
DE19529859A1 (de) 1997-02-20
US5719181A (en) 1998-02-17
DK0758647T3 (da) 2000-12-11
GR3035097T3 (en) 2001-03-30
EP0758647B1 (de) 2000-11-02
JPH0959270A (ja) 1997-03-04
PT758647E (pt) 2001-04-30

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