ES2148837T3 - Procedimiento para la preparacion del 1,4,7,10-tetraaza-ciclododecano y sus derivados. - Google Patents

Procedimiento para la preparacion del 1,4,7,10-tetraaza-ciclododecano y sus derivados.

Info

Publication number
ES2148837T3
ES2148837T3 ES96946361T ES96946361T ES2148837T3 ES 2148837 T3 ES2148837 T3 ES 2148837T3 ES 96946361 T ES96946361 T ES 96946361T ES 96946361 T ES96946361 T ES 96946361T ES 2148837 T3 ES2148837 T3 ES 2148837T3
Authority
ES
Spain
Prior art keywords
derivatives
cyclododecan
tetraaza
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96946361T
Other languages
English (en)
Inventor
Orlin Petrov
Annette Prelle
Klaus Graske
Klaus Nickisch
Bernd Raduchel
Johannes Platzek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2148837T3 publication Critical patent/ES2148837T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

LA INVENCION TRATA DE UN PROCEDIMIENTO PARA PREPARAR 1,4,7,10 TETRAAZACICLODODECAN (CICLENOS) Y SUS DERIVADOS A ESCALA INDUSTRIAL MEDIANTE CICLOTETRAMERIZACION DE BENCILAZIRIDINA PREPARADA IN SITU.
ES96946361T 1996-02-26 1997-02-26 Procedimiento para la preparacion del 1,4,7,10-tetraaza-ciclododecano y sus derivados. Expired - Lifetime ES2148837T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19608307A DE19608307C1 (de) 1996-02-26 1996-02-26 Verfahren zur Herstellung von 1,4,7,10-Tetraazacyclododecan und dessen Derivaten

Publications (1)

Publication Number Publication Date
ES2148837T3 true ES2148837T3 (es) 2000-10-16

Family

ID=7787168

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96946361T Expired - Lifetime ES2148837T3 (es) 1996-02-26 1997-02-26 Procedimiento para la preparacion del 1,4,7,10-tetraaza-ciclododecano y sus derivados.

Country Status (21)

Country Link
EP (1) EP0883610B1 (es)
JP (2) JP4745469B2 (es)
KR (1) KR100453668B1 (es)
CN (1) CN1081186C (es)
AT (1) ATE194602T1 (es)
AU (1) AU717720B2 (es)
CA (1) CA2247265C (es)
CZ (1) CZ290128B6 (es)
DE (2) DE19608307C1 (es)
DK (1) DK0883610T3 (es)
ES (1) ES2148837T3 (es)
GR (1) GR3034468T3 (es)
HK (1) HK1018618A1 (es)
IL (1) IL125419A (es)
NO (1) NO310870B1 (es)
NZ (1) NZ331520A (es)
PL (1) PL185927B1 (es)
PT (1) PT883610E (es)
SK (1) SK281972B6 (es)
WO (1) WO1997031905A1 (es)
ZA (1) ZA971672B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19608307C1 (de) * 1996-02-26 1997-08-28 Schering Ag Verfahren zur Herstellung von 1,4,7,10-Tetraazacyclododecan und dessen Derivaten
CZ2005653A3 (cs) * 2005-10-17 2007-01-10 Azacycles S. R. O. Způsob přípravy 1,4,7,10-tetraazacyklododekanua jeho N-acylderivátů
DE102009057274B4 (de) 2009-12-02 2011-09-01 Bayer Schering Pharma Aktiengesellschaft Gadobutrolherstellung mittels Trioxobicyclo-octan
DE102010013833A1 (de) 2010-03-29 2011-09-29 Bayer Schering Pharma Aktiengesellschaft Herstellung von Gadobutrol mittels Dimethylformamiddimethylacetal
CN101845112B (zh) * 2010-06-02 2011-09-14 华东理工大学 一种基于高分子纳米粒子的高灵敏性核磁共振成像造影剂的制备方法
DE102010023105A1 (de) 2010-06-04 2011-12-08 Bayer Schering Pharma Aktiengesellschaft Gadobutrolherstellung im Eintopfverfahren mittels DMF-acetal und N-Methylimidazol
KR102003570B1 (ko) * 2011-04-21 2019-07-24 바이엘 인텔렉쳐 프로퍼티 게엠베하 고순도 가도부트롤의 제조
KR102067551B1 (ko) * 2018-04-12 2020-01-17 (주) 에프엔지리서치 오염토양 또는 오염수질 복원용 화합물
CN108794417A (zh) * 2018-08-04 2018-11-13 许昌恒生制药有限公司 一种医疗诊断造影剂中间体的制备方法
EP4335461A1 (en) 2022-09-09 2024-03-13 Bayer AG Combinations of contrast agents
EP4335840A1 (en) 2022-09-09 2024-03-13 Bayer Aktiengesellschaft New contrast agents for use in diagnostic imaging

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3828023A (en) * 1971-09-13 1974-08-06 Dow Chemical Co Process for preparing cyclic oligomers of n-substituted aziridines
US6693190B1 (en) * 1994-05-11 2004-02-17 Bracco International B.V. Enhanced relaxivity monomeric and multimeric compounds
US6048979A (en) * 1995-03-10 2000-04-11 Nycomed Salutar, Inc. Preparation of N-arylmethyl aziridine derivatives, 1,4,7,10-tetraazacyclododecane derivatives obtained therefrom and N-arylmethyl-ethanol-amine sulphonate esters as intermediates
DE19608307C1 (de) * 1996-02-26 1997-08-28 Schering Ag Verfahren zur Herstellung von 1,4,7,10-Tetraazacyclododecan und dessen Derivaten

Also Published As

Publication number Publication date
NO983901D0 (no) 1998-08-25
PT883610E (pt) 2000-10-31
ATE194602T1 (de) 2000-07-15
SK117298A3 (en) 1999-01-11
ZA971672B (en) 1997-08-29
IL125419A (en) 2001-01-11
HK1018618A1 (en) 1999-12-30
CA2247265C (en) 2005-06-21
EP0883610B1 (de) 2000-07-12
DE19608307C1 (de) 1997-08-28
CN1211975A (zh) 1999-03-24
NO310870B1 (no) 2001-09-10
CA2247265A1 (en) 1997-09-04
JP2000505467A (ja) 2000-05-09
IL125419A0 (en) 1999-03-12
SK281972B6 (sk) 2001-09-11
PL185927B1 (pl) 2003-09-30
DE59702009D1 (de) 2000-08-17
CZ290128B6 (cs) 2002-06-12
NZ331520A (en) 2000-01-28
EP0883610A1 (de) 1998-12-16
AU717720B2 (en) 2000-03-30
JP2009185077A (ja) 2009-08-20
KR100453668B1 (ko) 2004-12-16
CN1081186C (zh) 2002-03-20
NO983901L (no) 1998-08-25
AU1877297A (en) 1997-09-16
PL328468A1 (en) 1999-02-01
DK0883610T3 (da) 2000-09-25
GR3034468T3 (en) 2000-12-29
WO1997031905A1 (de) 1997-09-04
KR19990087248A (ko) 1999-12-15
JP4745469B2 (ja) 2011-08-10
CZ272198A3 (cs) 2000-02-16

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