ES2147752T3 - Descontaminacion de plaquetas con 8-metoxipsoraleno. - Google Patents

Descontaminacion de plaquetas con 8-metoxipsoraleno.

Info

Publication number
ES2147752T3
ES2147752T3 ES93907082T ES93907082T ES2147752T3 ES 2147752 T3 ES2147752 T3 ES 2147752T3 ES 93907082 T ES93907082 T ES 93907082T ES 93907082 T ES93907082 T ES 93907082T ES 2147752 T3 ES2147752 T3 ES 2147752T3
Authority
ES
Spain
Prior art keywords
metoxypsoralene
decontamination
platelets
presented
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93907082T
Other languages
English (en)
Inventor
Lily Lin
Laurence Corash
Stephen T Isaacs
Carl V Hanson
George D Cimino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cerus Corp
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerus Corp filed Critical Cerus Corp
Application granted granted Critical
Publication of ES2147752T3 publication Critical patent/ES2147752T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/124—Disinfecting agents, e.g. antimicrobials
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/168—Physical preservation processes using electromagnetic fields or radiation; using acoustic waves or corpuscular radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3616—Batch-type treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Dentistry (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

SE PRESENTAN METODOS Y COMPOSICIONES PARA TRATAR CONTAMINANTES EN UN MATERIAL DISPUESTO PARA SU USO IN VIVO, EN PARTICULAR SANGRE Y PRODUCTOS SANGUINEOS PARA USO HUMANO. SE PRESENTA UN METODO PARA LA INACTIVACION DE LOS CONTAMINANTES EN LAS PREPARACIONES DE CELULAS SANGUINEAS ANTES DE SU ALMACENAMIENTO POR UN LARGO PERIODO DE TIEMPO Y SU TRANSFUSION.
ES93907082T 1992-03-02 1993-02-26 Descontaminacion de plaquetas con 8-metoxipsoraleno. Expired - Lifetime ES2147752T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/844,790 US5288605A (en) 1992-03-02 1992-03-02 Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen

Publications (1)

Publication Number Publication Date
ES2147752T3 true ES2147752T3 (es) 2000-10-01

Family

ID=25293640

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93907082T Expired - Lifetime ES2147752T3 (es) 1992-03-02 1993-02-26 Descontaminacion de plaquetas con 8-metoxipsoraleno.

Country Status (12)

Country Link
US (1) US5288605A (es)
EP (1) EP0633721B1 (es)
JP (1) JP3502095B2 (es)
AT (1) ATE193418T1 (es)
AU (1) AU663939B2 (es)
CA (1) CA2131168C (es)
DE (1) DE69328777T2 (es)
DK (1) DK0633721T3 (es)
ES (1) ES2147752T3 (es)
GR (1) GR3034069T3 (es)
PT (1) PT633721E (es)
WO (1) WO1993017553A1 (es)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5418130A (en) 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US5372929A (en) * 1992-01-27 1994-12-13 Cimino; George D. Methods for measuring the inactivation of pathogens
US5709991A (en) * 1992-03-02 1998-01-20 Cerus Corporation Proralen inactivation of microorganisms and psoralen removal
US5618662A (en) * 1992-03-02 1997-04-08 Cerus Corporation Intravenous administration of psoralen
US5459030A (en) * 1992-03-02 1995-10-17 Steritech, Inc. Synthetic media compositions for inactivating bacteria and viruses in blood preparations with 8-methoxypsoralen
US6433343B1 (en) 1992-03-02 2002-08-13 Cerus Corporation Device and method for photoactivation
WO1996014740A1 (en) * 1992-03-02 1996-05-23 Cerus Corporation Synthetic media for blood components
SE9201413L (sv) * 1992-04-30 1993-10-31 Stiftelsen Foer Medicinsk Tekn Beredning och sätt för aferesframställning av trombocytkoncentrat med väsentligt förlängd hållbarhet
DK0653911T3 (da) * 1992-08-07 2000-10-02 Cerus Corp Fremgangsmåder til inaktivering af bakterier i blodpræparater med 8-methoxypsoralen
US6420570B1 (en) 1993-06-28 2002-07-16 Cerus Corporation Psoralen compounds
US5712085A (en) 1993-06-28 1998-01-27 Cerus Corporation 5'-(4-amino-2-oxa)butye-4,4', 8-trinethylpsoralen in synthetic medium
US5399719A (en) 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
EP0727938B1 (en) * 1993-11-10 2003-06-18 Cerus Corporation Device and method for photoactivation
FR2712493B1 (fr) * 1993-11-16 1996-01-19 Centre Nat Rech Scient Utilisation de photosensibilisateurs dérivés du noyau phorbine pour la décontamination du sang infecté par des parasites et/ou des virus.
US5660731A (en) * 1994-11-08 1997-08-26 Pall Corporation Filter for separating photoactive agent
US5663043A (en) * 1995-01-04 1997-09-02 Hemasure Inc. Method for inactivating non-enveloped viruses using a viricide-potentiating agent with a photoactivatible virucide
US5658271A (en) * 1996-02-08 1997-08-19 Loubser; Paul G. Closed circuit autologous sequestration reservoir system
EP0910428B1 (en) * 1996-03-29 2005-10-26 Therakos, Inc. Photopheresis treatment of chronic hcv infections
ATE300298T1 (de) * 1996-03-29 2005-08-15 Therakos Inc Behandlung von leukocyten durch photopheresis
AU714882B2 (en) 1996-04-09 2000-01-13 Therakos, Inc. Method for removal of psoralens from biological fluids
US20020115585A1 (en) * 1996-06-07 2002-08-22 Hei Derek J. Method and devices for the removal of psoralens from blood products
US5922278A (en) † 1996-11-19 1999-07-13 Baxter International Inc. Method and apparatus for inactivating contaminants in biological fluid
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
AU752616B2 (en) * 1997-07-10 2002-09-26 Therakos, Inc. Treatment of inflammatory disorders of the bowel and urinary bladder
AU747842B2 (en) 1997-11-20 2002-05-23 Cerus Corporation New psoralens for pathogen inactivation
US7611831B2 (en) * 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US20070099170A1 (en) * 1998-07-21 2007-05-03 Navigant Biotechnologies, Inc. Method for treatment and storage of blood and blood products using endogenous alloxazines and acetate
US6258577B1 (en) 1998-07-21 2001-07-10 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers
US20030215784A1 (en) * 1998-07-21 2003-11-20 Dumont Larry Joe Method and apparatus for inactivation of biological contaminants using photosensitizers
US7049110B2 (en) * 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US7498156B2 (en) * 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US6193681B1 (en) * 1998-09-14 2001-02-27 American Immuno Tech, Llc. Septicemia prevention and treatment system
US7068361B2 (en) * 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US6565802B1 (en) 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light
US6219584B1 (en) 1999-07-09 2001-04-17 Therakos, Inc. Method and system for determining an effective amount of light energy to delivery to fluids having targets for the light energy
US7220747B2 (en) 1999-07-20 2007-05-22 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
US7094378B1 (en) 2000-06-15 2006-08-22 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US8722422B2 (en) 1999-09-03 2014-05-13 Therakos, Inc. Uninterrupted flow pump apparatus and method
US6495366B1 (en) 1999-09-03 2002-12-17 Therakos, Inc. Uninterrupted flow pump apparatus and method
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US6793643B1 (en) 2000-04-21 2004-09-21 Therakos, Inc. Low extracorporeal volume treatment system
US7985588B2 (en) * 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
US7648699B2 (en) * 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US6843961B2 (en) * 2000-06-15 2005-01-18 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US6548241B1 (en) 2000-11-28 2003-04-15 Gambro, Inc. Storage solution containing photosensitizer for inactivation of biological contaminants
US20030141260A1 (en) * 2001-12-28 2003-07-31 Frank Corbin Oxygen-enhanced pathogen inactivation
US20090023130A1 (en) * 2003-02-28 2009-01-22 Caridianbct Biotechnologies, Llc Prevention of Transfusion Related Acute Lung Injury Using Riboflavin and Light
US20040185426A1 (en) * 2003-03-17 2004-09-23 Mallett Scott R. Ultraviolet light and filter apparatus for treatment of blood
US7229427B2 (en) * 2003-03-17 2007-06-12 Hemavation Irradiation and filter device for treatment of blood
US7201730B2 (en) * 2003-03-17 2007-04-10 Hemavation, Llc Device and method for reducing inflammatory mediators in blood
US7207964B2 (en) * 2003-03-17 2007-04-24 Hemavation, Llc Apparatus and method for down-regulating immune system mediators in blood
US20040186412A1 (en) * 2003-03-17 2004-09-23 Mallett Scott R. Extracorporeal blood treatment system using ultraviolet light and filters
US20040185041A1 (en) * 2003-03-17 2004-09-23 Henna Vation, Llc Method for extracorporeal treatment of blood
US20040182783A1 (en) * 2003-03-17 2004-09-23 Walker Kimberly A. Filter and concentrator device for treatment of blood
US20040186407A1 (en) * 2003-03-17 2004-09-23 Kimberly Walker Concentrator and filter apparatus for treatment of blood
EP1912681A2 (en) * 2005-07-06 2008-04-23 Navigant Biotechnologies, LLC Methods for reducing pathogens in biological samples
RU2010107157A (ru) * 2007-08-01 2011-09-10 Каридианбст Байотекнолоджиз, Ллс (Us) Инактивация патогенов цельной крови
US8968992B2 (en) * 2008-03-21 2015-03-03 Fenwal, Inc. Red blood cell storage medium for extended storage
US8871434B2 (en) * 2008-03-21 2014-10-28 Fenwal, Inc. Red blood cell storage medium for extended storage
EP2490751B1 (en) 2009-10-23 2016-11-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
WO2016210374A1 (en) 2015-06-26 2016-12-29 Cerus Corporation Cryoprecipitate compositions and methods of preparation thereof
CA3003097A1 (en) 2015-10-23 2017-04-27 Cerus Corporation Plasma compositions and methods of use thereof
WO2018119462A1 (en) 2016-12-23 2018-06-28 Cerus Corporation Systems and methods for testing and screening using compound bound substrates
MX390725B (es) 2017-03-03 2025-03-21 Cerus Corp Kits y metodos para preparar composiciones de plaquetas con patogeno inactivado.
AU2018395525B2 (en) * 2017-12-29 2023-09-14 Cerus Corporation Systems and methods for treating biological fluids
BR112021025784A2 (pt) 2019-06-22 2022-03-03 Cerus Corp Sistemas de tratamento de fluido biológico
WO2020264421A1 (en) 2019-06-28 2020-12-30 Cerus Corporation System and methods for implementing a biological fluid treatment device
DE102020131487A1 (de) * 2020-11-27 2022-06-02 Lippert Gmbh & Co. Kg Vorrichtung zur Desinfektion von Paketen oder Stückgut

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196281A (en) * 1976-10-20 1980-04-01 Regents Of The University Of California Psoralens
US4169204A (en) * 1976-10-20 1979-09-25 Regents Of The University Of California Psoralens
US4124598A (en) * 1976-10-20 1978-11-07 Hoffmann-La Roche Inc. Psoralens
US4321919A (en) * 1979-12-11 1982-03-30 Leukocyte Research, Inc. Method and system for externally treating human blood
DE3483751D1 (de) * 1983-05-02 1991-01-31 Diamond Scient Co Photochemische entkeimungsbehandlung von vollem blut oder blutbestandteilen.
US4748120A (en) * 1983-05-02 1988-05-31 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4727027A (en) * 1983-05-02 1988-02-23 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
DK507185A (da) * 1984-11-05 1986-05-06 Du Pont Fremgangsmaade til inaktivering af human tumor leukaemi virus iii
US4944920A (en) * 1986-08-01 1990-07-31 University Of Southern California Novel method to treat blood
US4878891A (en) * 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
DE3805459A1 (de) * 1988-02-22 1989-08-31 Biotest Pharma Gmbh Verfahren zur sterilisation von blut, plasma, blut- und plasmaderivaten, zellsuspensionen oder dgl.
US4960408A (en) * 1989-01-10 1990-10-02 Klainer Albert S Treatment methods and vaccines for stimulating an immunological response against retroviruses
US4997577A (en) * 1989-12-20 1991-03-05 Baxter International Inc. Systems and methods for removing undesired matter from blood cells

Also Published As

Publication number Publication date
DE69328777D1 (de) 2000-07-06
JPH08501058A (ja) 1996-02-06
CA2131168A1 (en) 1993-09-16
CA2131168C (en) 2003-05-27
WO1993017553A1 (en) 1993-09-16
DK0633721T3 (da) 2000-10-09
EP0633721B1 (en) 2000-05-31
GR3034069T3 (en) 2000-11-30
AU3781093A (en) 1993-10-05
DE69328777T2 (de) 2000-11-30
US5288605A (en) 1994-02-22
EP0633721A4 (en) 1996-07-03
AU663939B2 (en) 1995-10-26
EP0633721A1 (en) 1995-01-18
ATE193418T1 (de) 2000-06-15
PT633721E (pt) 2000-10-31
JP3502095B2 (ja) 2004-03-02

Similar Documents

Publication Publication Date Title
ES2147752T3 (es) Descontaminacion de plaquetas con 8-metoxipsoraleno.
ES2147203T3 (es) Procedimientos de inactivacion de bacterias en las preparaciones a base de sangre con la ayuda de 8-metoxipsoraleno.
DE69432832D1 (de) Vorrichtung und verfahren zur photoaktivierung
ES2063013T3 (es) Procedimiento para eliminar pirogenos.
BR9507853A (pt) Sistema para implante mecãnico de raizes de cabelo na pele
FI892343L (fi) Menetelmä kuumuudelle ja korroosiolle herkkien lääketieteellisten välineiden, erityisesti endoskooppien, puhdistamiseksi ja desinfioimiseksi ja aine menetelmän toteuttamiseksi
ES290656Y (es) Dispositivo para recoger y mantener vivos los cultivos del cuerpo del paciente.
DK140390A (da) Beholder til adskilt, steril opbevaring af mindst to substanser og til sammenblanding af disse
FI945586A7 (fi) Selektiivinen solujen inaktivointi veressä
NO884022L (no) Steriliseringspakning for engangsbruk.
IT8819567A0 (it) Metodo per sterilizzare oggetti da sterilizzare e dispositivo di sterilizzazione.
BR8905985A (pt) Composicao liquida aquosa para tratamento de tecidos
ATA113492A (de) Mehrfachbeutelsystem zur sterilen behandlung von menschlichen blutkonserven
IT1185123B (it) Dispositivo e procedimento per sterilizzare articoli,in particolare strumenti chirurgici,strumenti odontotecnici e simili
KR900700396A (ko) 식염수 용액을 함유하는 살균처리된 에어로솔 용기 및 용기의 살균 방법
ES2063056T3 (es) Esteres poliaromaticos de antibioticos macrolidicos y lincosamidicos, su procedimiento de preparacion y composiciones farmaceuticas y cosmeticas que los contienen.
DK289388D0 (da) Desinfektionsmiddel til at desinficere hud og overflader paa genstande
ATE75938T1 (de) Enantiomere des propafenons enthaltende therapeutische mittel.
KR890001887U (ko) 산림의 유해식물 제거용 약물주사기
ITRM920216A0 (it) Set per soluzione salina sterile ad uso chirurgico.
MX9207146A (es) Procedimiento para la fabricacion de una emulsion capilar que resuelve problemas de calvicie.
PL254943A1 (en) Sterilizer for killing microorganisms in particular for use in an artificial kidney dialyzer
FI873524A7 (fi) Desinfiointiliuos ja -menetelmä
KR880017512U (ko) 1회용 의료 소독구
FI905060A7 (fi) Menetelmä sellaisten liposomien ja/tai biologisten solujen valmistamis eksi, joihin on absorboitunut aineita, sekä niiden käyttö

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 633721

Country of ref document: ES