ES2145823T3 - Agente para la profilaxis o el tratamiento de cataratas. - Google Patents

Agente para la profilaxis o el tratamiento de cataratas.

Info

Publication number
ES2145823T3
ES2145823T3 ES94907086T ES94907086T ES2145823T3 ES 2145823 T3 ES2145823 T3 ES 2145823T3 ES 94907086 T ES94907086 T ES 94907086T ES 94907086 T ES94907086 T ES 94907086T ES 2145823 T3 ES2145823 T3 ES 2145823T3
Authority
ES
Spain
Prior art keywords
pct
prophylaxis
treatment
agent
methylbenzoylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94907086T
Other languages
English (en)
Inventor
Yoshitaka Yamamura
Tatsuya Yamashita
Shigeki Nakamura
Toshiyuki Onogawa
Yoshihisa Yamada
Kenji Tsujimae
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2145823T3 publication Critical patent/ES2145823T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UN AGENTE PARA LA PROFILAXIS O TRATAMIENTO DE CATARATAS, QUE COMPRENDE COMO UN INGREDIENTE ACTIVO AL MENOS UN COMPUESTO SELECCIONADO DEL GRUPO CONSISTENTE EN UN COMPUESTO DE CARBOESTIRILO DE FORMULA (1), EN DONDE R{SUP,1} ES UN GRUPO ALKOXI BAJO DE ALKANOILO SUSTITUIDO BAJO, Y EL ENLACE ENTRE LAS 3- Y 4-POSICIONES DEL NUCLEO DE CARBOESTIRILO ES UN ENLACE SIMPLE O UN ENLACE DOBLE, O UNA SAL DEL MISMO, 5-DIMETILAMINO-1-[[]4(()2-METILBENZOILAMINO())BENZOILO[]]-2,3,4,5-TETRAHIDRO-1HBENZACEPINA Y 5-HIDROXI-7-CLORO-1-[[]2-METILO-4-(()METILOBEZOILAMINO())BENZOILO[]]-2,3,4,5-TETRAHIDRO-1H-BENZACEPINA, UN METODO PARA PROFILAXIS O TRATAMIENTO DE CATARATAS QUE UTILIZA EL MISMO.
ES94907086T 1993-02-23 1994-02-22 Agente para la profilaxis o el tratamiento de cataratas. Expired - Lifetime ES2145823T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3289693 1993-02-23

Publications (1)

Publication Number Publication Date
ES2145823T3 true ES2145823T3 (es) 2000-07-16

Family

ID=12371661

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94907086T Expired - Lifetime ES2145823T3 (es) 1993-02-23 1994-02-22 Agente para la profilaxis o el tratamiento de cataratas.

Country Status (13)

Country Link
US (1) US5827862A (es)
EP (1) EP0686035B1 (es)
KR (1) KR100197065B1 (es)
CN (1) CN1120810A (es)
AT (1) ATE192041T1 (es)
AU (1) AU668024B2 (es)
CA (1) CA2156497A1 (es)
DE (1) DE69424156T2 (es)
DK (1) DK0686035T3 (es)
ES (1) ES2145823T3 (es)
MX (1) MX9401350A (es)
TW (1) TW354762B (es)
WO (1) WO1994018975A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09505057A (ja) * 1993-11-19 1997-05-20 ザ・ユニバーシティ・オブ・シドニー 白内障を予防または制御するための方法
DE19748763A1 (de) * 1997-11-05 1999-05-06 Hans Peter Zenner Verwendung von Vasopressin-Antagonisten
US7030149B2 (en) 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
TWI322689B (en) * 2003-02-24 2010-04-01 Otsuka Pharma Co Ltd Method for treating severe heart failure and medicament therefor
US7220422B2 (en) * 2003-05-20 2007-05-22 Allergan, Inc. Methods and compositions for treating eye disorders
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US20070015691A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
PT1919874E (pt) * 2005-09-02 2011-03-14 Otsuka Pharma Co Ltd Processo para preparar compostos de benzazepina ou sais dos mesmos
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
CN107915752B (zh) * 2017-11-14 2018-09-18 牡丹江医学院 一种治疗白内障的药物及其制备方法
WO2020123312A1 (en) 2018-12-09 2020-06-18 Weinberg Assa Method to prevent and treat macular degeneration by vasodilators
WO2020123852A1 (en) * 2018-12-15 2020-06-18 Weinberg Assa Method to prevent and treat ocular cataract by calcium channel blockers, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69009785T2 (de) * 1989-02-10 1994-11-03 Otsuka Pharma Co Ltd Carbostyrilderivate.
JP2905909B2 (ja) * 1991-04-19 1999-06-14 大塚製薬株式会社 バソプレシン拮抗剤
DK0450097T3 (da) * 1989-10-20 1996-05-20 Otsuka Pharma Co Ltd Benzoheterocykliske forbindelser

Also Published As

Publication number Publication date
EP0686035A1 (en) 1995-12-13
DE69424156T2 (de) 2000-09-14
CN1120810A (zh) 1996-04-17
AU668024B2 (en) 1996-04-18
US5827862A (en) 1998-10-27
CA2156497A1 (en) 1994-09-01
KR100197065B1 (ko) 1999-06-15
EP0686035B1 (en) 2000-04-26
DK0686035T3 (da) 2000-08-07
KR960700719A (ko) 1996-02-24
MX9401350A (es) 1994-08-31
DE69424156D1 (de) 2000-05-31
AU6046094A (en) 1994-09-14
TW354762B (en) 1999-03-21
ATE192041T1 (de) 2000-05-15
WO1994018975A1 (en) 1994-09-01

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