ES2144291T3 - Utilizacion de agentes antagonistas no peptidicos de bradiquinina para el tratamiento y la prevencion de enfermedades hepaticas cronicas-fibrogeneticas, enfermedades hepaticas agudas y complicaciones ligadas a ellas. - Google Patents
Utilizacion de agentes antagonistas no peptidicos de bradiquinina para el tratamiento y la prevencion de enfermedades hepaticas cronicas-fibrogeneticas, enfermedades hepaticas agudas y complicaciones ligadas a ellas.Info
- Publication number
- ES2144291T3 ES2144291T3 ES97108096T ES97108096T ES2144291T3 ES 2144291 T3 ES2144291 T3 ES 2144291T3 ES 97108096 T ES97108096 T ES 97108096T ES 97108096 T ES97108096 T ES 97108096T ES 2144291 T3 ES2144291 T3 ES 2144291T3
- Authority
- ES
- Spain
- Prior art keywords
- hepatic diseases
- chronic
- treatment
- bradiquinine
- fibrogenetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 201000010099 disease Diseases 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 4
- 230000002440 hepatic effect Effects 0.000 title abstract 4
- 239000005557 antagonist Substances 0.000 title abstract 2
- 230000001154 acute effect Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 201000011200 hepatorenal syndrome Diseases 0.000 abstract 1
- 230000001631 hypertensive effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 208000007232 portal hypertension Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pyridine Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1996120509 DE19620509A1 (de) | 1996-05-22 | 1996-05-22 | Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen |
DE19632042A DE19632042A1 (de) | 1996-08-08 | 1996-08-08 | Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen |
DE19639303A DE19639303A1 (de) | 1996-09-25 | 1996-09-25 | Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen |
US08/858,550 US5786365A (en) | 1996-05-22 | 1997-05-19 | Use of nonpeptide bradykinin antagonists for the treatment and prevention of chronic fibrogenetic liver disorders, acute liver disorders and the complications associated therewith |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2144291T3 true ES2144291T3 (es) | 2000-06-01 |
Family
ID=27438369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97108096T Expired - Lifetime ES2144291T3 (es) | 1996-05-22 | 1997-05-20 | Utilizacion de agentes antagonistas no peptidicos de bradiquinina para el tratamiento y la prevencion de enfermedades hepaticas cronicas-fibrogeneticas, enfermedades hepaticas agudas y complicaciones ligadas a ellas. |
Country Status (23)
Country | Link |
---|---|
US (1) | US5786365A (ja) |
EP (2) | EP0808627A2 (ja) |
JP (1) | JP4034849B2 (ja) |
CN (1) | CN1176102A (ja) |
AT (1) | ATE189389T1 (ja) |
AU (1) | AU2351197A (ja) |
BR (1) | BR9703367A (ja) |
CA (1) | CA2205780A1 (ja) |
CZ (1) | CZ154697A3 (ja) |
DE (1) | DE59701078D1 (ja) |
DK (1) | DK0808628T3 (ja) |
ES (1) | ES2144291T3 (ja) |
GR (1) | GR3033048T3 (ja) |
HR (1) | HRP970278A2 (ja) |
HU (1) | HUP9700913A1 (ja) |
ID (1) | ID18447A (ja) |
IL (1) | IL120862A0 (ja) |
NO (1) | NO972311L (ja) |
PL (1) | PL320134A1 (ja) |
PT (1) | PT808628E (ja) |
SI (1) | SI0808628T1 (ja) |
SK (1) | SK63097A3 (ja) |
TR (1) | TR199700392A2 (ja) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5935581A (en) * | 1996-07-24 | 1999-08-10 | Kapadia; Govind J. | Inhibitory effects of synthetic and natural colorants on carcinogenesis |
DE19653969A1 (de) * | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
DE19712960A1 (de) | 1997-03-27 | 1998-10-01 | Hoechst Ag | Benzyloxy-substituierte, anellierte N-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Bradykininrezeptorantagonisten |
WO2000027415A2 (en) | 1998-11-10 | 2000-05-18 | Temple University - Of The Commonwealth System Of Higher Education | Inhibition of angiogenesis by peptide analogs of high molecular weight kininogen domain 5 |
AU773862B2 (en) * | 1998-11-10 | 2004-06-10 | Temple University - Of The Commonwealth System Of Higher Education | Inhibition of angiogenesis by high molecular weight kininogen and peptide analogs thereof |
US6767889B1 (en) | 1998-11-10 | 2004-07-27 | Temple University Of The Commonwealth System Of Higher Education | Inhibition of angiogenesis by high molecular weight kininogen and peptide analogs thereof |
US6869931B1 (en) | 1998-12-16 | 2005-03-22 | Temple University - Of The Commonwealth System Of Higher Education | Inhibition of angiogenesis by high molecular weight kininogen domain 3 peptide analogs |
US6994852B1 (en) * | 1999-11-12 | 2006-02-07 | Temple University-Of The Commonwealth System Of Higher Education | Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5 |
US6445588B1 (en) | 2001-01-02 | 2002-09-03 | Motorola, Inc. | Apparatus and method for securing a printed circuit board to a base plate |
BRPI0417543A (pt) | 2003-12-12 | 2007-03-27 | Wyeth Corp | quinolinas úteis no tratamento de doença cardiovascular |
AU2006228957A1 (en) * | 2005-04-01 | 2006-10-05 | Methylgene Inc. | Inhibitors of histone deacetylase |
US10517765B2 (en) | 2010-06-29 | 2019-12-31 | Jennifer DiGrazia | Wound and bandage protection system and method |
CA2839850A1 (en) * | 2010-06-29 | 2012-01-12 | Jennifer Digrazia | Wound and bandage protection system and method |
RU2514345C1 (ru) * | 2012-10-09 | 2014-04-27 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежская государственная медицинская академия им. Н.Н. Бурденко" Министерства здравоохранения и социального развития Российской Федерации | Способ прогнозирования степени риска геморрагических осложнений при миниинвазивных хирургических вмешательствах на печени |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5212182A (en) * | 1990-10-03 | 1993-05-18 | American Home Products Corpooration | Substituted quinolinyl- and naphthalenylbenzamides or benzylamines and related compounds useful as analgesics |
US5216165A (en) * | 1990-10-03 | 1993-06-01 | American Home Products Corporation | N-substituted aminoquinolines as analgesic agents |
US5438064A (en) * | 1991-12-23 | 1995-08-01 | American Home Products Corporation | Derivatives of 4-anilinoquinoline-3-carboxamide as analgesic agents |
AU686115B2 (en) * | 1992-11-02 | 1998-02-05 | Fujisawa Pharmaceutical Co., Ltd. | Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation |
AU680870B2 (en) * | 1993-04-28 | 1997-08-14 | Astellas Pharma Inc. | New heterocyclic compounds |
JP3049648B2 (ja) * | 1993-12-13 | 2000-06-05 | 日立金属株式会社 | 加圧成形方法および加圧成形機 |
EP0774462A4 (en) * | 1994-08-03 | 1997-10-29 | Fujisawa Pharmaceutical Co | HETEROCYCLIC COMPOUND |
-
1997
- 1997-05-09 EP EP97107624A patent/EP0808627A2/de not_active Withdrawn
- 1997-05-19 US US08/858,550 patent/US5786365A/en not_active Expired - Lifetime
- 1997-05-20 AT AT97108096T patent/ATE189389T1/de active
- 1997-05-20 DK DK97108096T patent/DK0808628T3/da active
- 1997-05-20 IL IL12086297A patent/IL120862A0/xx unknown
- 1997-05-20 ES ES97108096T patent/ES2144291T3/es not_active Expired - Lifetime
- 1997-05-20 AU AU23511/97A patent/AU2351197A/en not_active Abandoned
- 1997-05-20 EP EP97108096A patent/EP0808628B1/de not_active Expired - Lifetime
- 1997-05-20 TR TR97/00392A patent/TR199700392A2/xx unknown
- 1997-05-20 SI SI9730031T patent/SI0808628T1/xx unknown
- 1997-05-20 PT PT97108096T patent/PT808628E/pt unknown
- 1997-05-20 DE DE59701078T patent/DE59701078D1/de not_active Expired - Lifetime
- 1997-05-20 HU HU9700913A patent/HUP9700913A1/hu unknown
- 1997-05-20 CZ CZ971546A patent/CZ154697A3/cs unknown
- 1997-05-20 SK SK630-97A patent/SK63097A3/sk unknown
- 1997-05-21 ID IDP971698A patent/ID18447A/id unknown
- 1997-05-21 CN CN97113108A patent/CN1176102A/zh active Pending
- 1997-05-21 HR HR19639303.5A patent/HRP970278A2/xx not_active Application Discontinuation
- 1997-05-21 JP JP13116097A patent/JP4034849B2/ja not_active Expired - Fee Related
- 1997-05-21 NO NO972311A patent/NO972311L/no unknown
- 1997-05-22 BR BR9703367A patent/BR9703367A/pt not_active Application Discontinuation
- 1997-05-22 CA CA002205780A patent/CA2205780A1/en not_active Abandoned
- 1997-05-22 PL PL97320134A patent/PL320134A1/xx unknown
-
2000
- 2000-03-24 GR GR20000400735T patent/GR3033048T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH1045624A (ja) | 1998-02-17 |
NO972311L (no) | 1997-11-24 |
DE59701078D1 (de) | 2000-03-09 |
HRP970278A2 (en) | 1998-04-30 |
GR3033048T3 (en) | 2000-08-31 |
EP0808628A3 (de) | 1998-01-14 |
DK0808628T3 (da) | 2000-06-26 |
HUP9700913A1 (hu) | 1999-09-28 |
ID18447A (id) | 1998-04-09 |
ATE189389T1 (de) | 2000-02-15 |
CZ154697A3 (en) | 1997-12-17 |
IL120862A0 (en) | 1997-09-30 |
NO972311D0 (no) | 1997-05-21 |
EP0808627A2 (de) | 1997-11-26 |
BR9703367A (pt) | 1998-09-15 |
SI0808628T1 (en) | 2000-04-30 |
AU2351197A (en) | 1997-11-27 |
HU9700913D0 (en) | 1997-07-28 |
SK63097A3 (en) | 1997-12-10 |
CN1176102A (zh) | 1998-03-18 |
PL320134A1 (en) | 1997-11-24 |
TR199700392A2 (xx) | 1997-12-21 |
EP0808628A2 (de) | 1997-11-26 |
US5786365A (en) | 1998-07-28 |
CA2205780A1 (en) | 1997-11-22 |
MX9703725A (es) | 1997-11-29 |
PT808628E (pt) | 2000-05-31 |
JP4034849B2 (ja) | 2008-01-16 |
EP0808628B1 (de) | 2000-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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