ES2143976T3 - Dispositivo para metodos ligando-receptor. - Google Patents

Dispositivo para metodos ligando-receptor.

Info

Publication number
ES2143976T3
ES2143976T3 ES91302003T ES91302003T ES2143976T3 ES 2143976 T3 ES2143976 T3 ES 2143976T3 ES 91302003 T ES91302003 T ES 91302003T ES 91302003 T ES91302003 T ES 91302003T ES 2143976 T3 ES2143976 T3 ES 2143976T3
Authority
ES
Spain
Prior art keywords
porous member
capillary
contact
sample
superior
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91302003T
Other languages
English (en)
Inventor
Mark Ronald Nowakowski
Kenneth Francis Buechler
Gunars Edward Valkirs
Richard Ray Anderson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alere San Diego Inc
Original Assignee
Biosite Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosite Diagnostics Inc filed Critical Biosite Diagnostics Inc
Application granted granted Critical
Publication of ES2143976T3 publication Critical patent/ES2143976T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Small-Scale Networks (AREA)
  • Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
  • Push-Button Switches (AREA)

Abstract

SE PRESENTAN DISPOSITIVOS PARA SU USO TANTO EN ENSAYOS DE LIGANDO-RECEPTOR TANTO COMPETITIVOS COMO NO COMPETITIVOS, QUE TIENE UN MIEMBRO MICROPOROSO EN CONTACTO CON UNA SUPERFICIE EN RELIEVE TEXTURADA NO ABSORVENTE, EN DONDE EL RELIEVE TEXTURADO DE LA SUPERFICIE ES TAL QUE SE FORMA UNA RED CAPILAR CUANDO ESTA EN CONTACTO CON EL MIEMBRO MICROPOROSO. MAS PARTICULARMENTE, ESTOS DISPOSITIVOS COMPRENDEN: UN MIEMBRO POROSO QUE TIENE UNA SUPERFICIE SUPERIOR Y OTRA INFERIOR, QUE ESTA POSICIONADO EN EL DISPOSITIVO DE TAL MANERA QUE DICHA MUESTRA PUEDE APLICARSE A DICHA SUPERFICIE SUPERIOR; UN MIEMBRO NO ABSORBENTE QUE TIENE UNA SUPERFICIE TEJIDA CON CANALES CAPACES DE FORMAR UNA RED DE CANALES CAPILARES CUANDO SE COLOCA EN COMUNICACION DETRAS O ALREDEDOR DE DICHO MIEMBRO POROSO, DICHA RED CAPILAR ES SUBSTANCIALMENTE PARALELA A LA SUPERFICIE INFERIOR DE DICHO MIEMBRO POROSO; MEDIANTE TODO ELLO, LA MUESTRA SOLA O EN COMBINACION CON OTROS FLUIDOS, CUANDO SE APLICA A DICHA SUPERFICIE SUPERIOR ES ABSORBIDA A TRAVES DE DICHO MIEMBRO POROSO HASTA LA RED CAPILAR FORMADA ENTRE EL MIEMBRO POROSO Y EL MIEMBRO NO ABSORBENTE CUANDO TODO EL VOLUMEN VACIO DE DICHO MIEMBRO POROSO SE LLENA SUBSTANCIALMENTE CON DICHA MUESTRA Y/O FLUIDOS Y CUANDO SE PRODUCE EL CONTACTO ENTRE DICHO MIEMBRO POROSO Y DICHO MIEMBRO NO ABSORBENTE. DICHOS DISPOSITIVOS SON ADECUADOS PARA SU USO EN ENSAYOS DE LIGANDO-RECEPTOR QUE SE REALIZAN USANDO BIEN METODOS INMUNOCROMATOGRAFICOS O EN AQUELLOS QUE SE REALIZAN USANDO METODOS DE FLUJO CONTINUO.
ES91302003T 1990-03-12 1991-03-11 Dispositivo para metodos ligando-receptor. Expired - Lifetime ES2143976T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50029990A 1990-03-12 1990-03-12

Publications (1)

Publication Number Publication Date
ES2143976T3 true ES2143976T3 (es) 2000-06-01

Family

ID=23988816

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91302003T Expired - Lifetime ES2143976T3 (es) 1990-03-12 1991-03-11 Dispositivo para metodos ligando-receptor.

Country Status (10)

Country Link
EP (1) EP0447154B1 (es)
JP (1) JP3070764B2 (es)
AT (1) ATE189309T1 (es)
AU (1) AU637480B2 (es)
CA (1) CA2037963C (es)
DE (1) DE69131933T2 (es)
ES (1) ES2143976T3 (es)
IE (1) IE70333B1 (es)
PT (1) PT97000B (es)
WO (1) WO1991013998A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6905882B2 (en) 1992-05-21 2005-06-14 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6767510B1 (en) 1992-05-21 2004-07-27 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US5379370A (en) * 1992-07-17 1995-01-03 International Business Machines Corporation Method and apparatus for drawing lines, curves, and points coincident with a surface
US5753517A (en) * 1996-03-29 1998-05-19 University Of British Columbia Quantitative immunochromatographic assays
US6165798A (en) * 1996-10-10 2000-12-26 University Of British Columbia Optical quantification of analytes in membranes
US7153651B1 (en) 1996-10-31 2006-12-26 Inverness Medical - Biostar, Inc. Flow-through optical assay devices providing laminar flow of fluid samples, and methods of construction thereof
EP0840123A1 (de) * 1996-11-05 1998-05-06 Cell Diagnostica, Gesellschaft für angewandte Zellbiologie mbH Vorrichtung zum quantifizierenden und differenzierden Nachweis verschiedener Biomoleküle in einem einzigen Testansatz
US5879951A (en) 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US5939252A (en) 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US6106779A (en) * 1997-10-02 2000-08-22 Biosite Diagnostics, Inc. Lysis chamber for use in an assay device
US6136610A (en) * 1998-11-23 2000-10-24 Praxsys Biosystems, Inc. Method and apparatus for performing a lateral flow assay
US6528323B1 (en) 1999-06-14 2003-03-04 Praxsys Biosystems, Inc. Bidirectional lateral flow test strip and method
MXPA02000144A (es) † 1999-07-07 2002-07-02 3M Innovative Properties Co Articulo de deteccion que tiene una pelicul a de control de fluidos.
US6136549A (en) * 1999-10-15 2000-10-24 Feistel; Christopher C. systems and methods for performing magnetic chromatography assays
JP3553045B2 (ja) 2000-05-26 2004-08-11 松下電器産業株式会社 バイオセンサ
EP1417491A4 (en) 2001-07-18 2004-08-11 Siliang Zhou TEST STRIP FOR SIDE FLOW ASSAY OF A SAMPLE CONTAINING WHOLE CELLS
WO2003016902A1 (en) * 2001-08-20 2003-02-27 Proteome Systems Intellectual Property Pty Ltd Diagnostic testing process and apparatus
AU2002331408B2 (en) 2001-08-20 2008-05-08 Proteome Systems Ltd Diagnostic testing process and apparatus
US7875435B2 (en) 2001-12-12 2011-01-25 Proteome Systems Ltd Diagnostic testing process
US7049150B2 (en) * 2001-12-28 2006-05-23 Varian, Inc. Binding assay device with non-absorbent carrier material
US7771922B2 (en) 2002-05-03 2010-08-10 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic device
US7214530B2 (en) 2002-05-03 2007-05-08 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices
GB2391068A (en) * 2002-07-18 2004-01-28 Sensor Tech Ltd A lateral flow through device comprising an electrochemical sesor
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
CN101031798B (zh) 2004-07-29 2012-06-27 瑞莱诊断体系有限公司 侧向流系统和测定
ES2812629T3 (es) * 2004-11-24 2021-03-17 Techlab Inc Dispositivo para la detección de analitos
US7491669B2 (en) * 2006-02-07 2009-02-17 Crystal Clear Technologies, Inc. Adsorbent with multiple layers
SE531948C2 (sv) * 2006-06-20 2009-09-15 Aamic Ab Analysanordning för vätskeprover innefattande filter i direkt kontakt med projektioner
JP5663574B2 (ja) 2009-07-20 2015-02-04 シロアム バイオサイエンシズ, インコーポレイテッドSiloam Biosciences, Inc. 微小流体分析プラットホーム
ES2702432B2 (es) 2017-08-31 2019-08-05 Venegas Pedro Manuel Medina Método y dispositivo para el análisis de ácidos nucleicos
US20220219164A1 (en) * 2019-04-24 2022-07-14 Denka Company Limited Membrane carrier and test kit

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754658A (fr) * 1969-08-12 1971-02-10 Merck Patent Gmbh Lamelle indicatrice, se composant d'une matiere capillaire impregnee, absorbante et gainee de feuilles
ZA733612B (en) * 1972-10-11 1974-04-24 Merck Patent Gmbh Container for test strips
US4233029A (en) * 1978-10-25 1980-11-11 Eastman Kodak Company Liquid transport device and method
US4301139A (en) * 1979-06-21 1981-11-17 Ames-Yissum Ltd. Multilayer column chromatography specific binding assay method, test device and test kit
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4757004A (en) * 1984-03-16 1988-07-12 Syntex (U.S.A.) Inc. Chromatographic devices having modified edges
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
AU592971B2 (en) * 1984-12-20 1990-02-01 Axis-Shield Poc As Solid phase diffusion assay
US4916056A (en) * 1986-02-18 1990-04-10 Abbott Laboratories Solid-phase analytical device and method for using same
WO1987006003A1 (en) * 1986-03-25 1987-10-08 P B Diagnostic Systems, Inc. Biological diagnostic device
US5079142A (en) * 1987-01-23 1992-01-07 Synbiotics Corporation Orthogonal flow immunoassays and devices
US4781710A (en) * 1987-05-15 1988-11-01 The Procter & Gamble Company Absorbent pad having improved liquid distribution
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US4902629A (en) * 1987-10-06 1990-02-20 Personal Diagnostics, Inc. Apparatus and processes for facilitating reaction between analyte and test reagent system
US5051237A (en) * 1988-06-23 1991-09-24 P B Diagnostic Systems, Inc. Liquid transport system
US5252496A (en) * 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
IE75720B1 (en) * 1990-10-08 1997-09-24 Akzo Nv Device for performing a rapid single manual assay

Also Published As

Publication number Publication date
EP0447154A2 (en) 1991-09-18
CA2037963A1 (en) 1991-09-13
IE910804A1 (en) 1991-10-09
EP0447154B1 (en) 2000-01-26
PT97000B (pt) 2001-03-30
EP0447154A3 (en) 1992-08-05
AU637480B2 (en) 1993-05-27
DE69131933T2 (de) 2000-05-31
IE70333B1 (en) 1996-11-13
AU7465091A (en) 1991-10-10
PT97000A (pt) 1993-05-31
ATE189309T1 (de) 2000-02-15
CA2037963C (en) 2000-12-05
JP3070764B2 (ja) 2000-07-31
WO1991013998A1 (en) 1991-09-19
JPH04506117A (ja) 1992-10-22
DE69131933D1 (de) 2000-03-02

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