ES2141849T3 - Composicion transdermica de n-(n-(5-(4-(aminoiminometil)fenil)-1-oxopentil)-l-alfa-aspartil)-l-fenilalanina o sus esteres y sus sales farmaceuticamente aceptables. - Google Patents

Composicion transdermica de n-(n-(5-(4-(aminoiminometil)fenil)-1-oxopentil)-l-alfa-aspartil)-l-fenilalanina o sus esteres y sus sales farmaceuticamente aceptables.

Info

Publication number
ES2141849T3
ES2141849T3 ES94931926T ES94931926T ES2141849T3 ES 2141849 T3 ES2141849 T3 ES 2141849T3 ES 94931926 T ES94931926 T ES 94931926T ES 94931926 T ES94931926 T ES 94931926T ES 2141849 T3 ES2141849 T3 ES 2141849T3
Authority
ES
Spain
Prior art keywords
esters
pharmaceutically acceptable
acceptable salts
oxopentil
fenilalanina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94931926T
Other languages
English (en)
Inventor
Larry P Feigen
Martin John Griffin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of ES2141849T3 publication Critical patent/ES2141849T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA PRESENTE INVENCION ES PARA COMPOSICIONES FARMACEUTICAS Y UN METODO DE USO PARA EL ENVIO TRANSDERMICO DE N-[N-[5-[4(AMINOIMINOMETIL)FENIL]-1-OXOPENTIL]-L-ALFA-ASPARTIL]-LFENILALANINA O SUS ESTERES Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, QUE SON UTILES COMO INHIBIDORES DE LA AGREGACION DE PLAQUETAS. EN LA FORMULA (I), R PUEDE SER INDEPENDIENTEMENTE HIDROGENO O ALQUILO DE 1 A 6 ATOMOS DE CARBONO.
ES94931926T 1993-11-19 1994-10-24 Composicion transdermica de n-(n-(5-(4-(aminoiminometil)fenil)-1-oxopentil)-l-alfa-aspartil)-l-fenilalanina o sus esteres y sus sales farmaceuticamente aceptables. Expired - Lifetime ES2141849T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15504493A 1993-11-19 1993-11-19

Publications (1)

Publication Number Publication Date
ES2141849T3 true ES2141849T3 (es) 2000-04-01

Family

ID=22553912

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94931926T Expired - Lifetime ES2141849T3 (es) 1993-11-19 1994-10-24 Composicion transdermica de n-(n-(5-(4-(aminoiminometil)fenil)-1-oxopentil)-l-alfa-aspartil)-l-fenilalanina o sus esteres y sus sales farmaceuticamente aceptables.

Country Status (11)

Country Link
EP (1) EP0729362B1 (es)
JP (1) JPH09505290A (es)
AT (1) ATE188611T1 (es)
AU (1) AU8083894A (es)
CA (1) CA2176462A1 (es)
DE (1) DE69422637T2 (es)
DK (1) DK0729362T3 (es)
ES (1) ES2141849T3 (es)
GR (1) GR3032697T3 (es)
PT (1) PT729362E (es)
WO (1) WO1995013825A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2298378T3 (es) 2001-06-28 2008-05-16 Novo Nordisk A/S Formulacion estable de glp-1 modificado.
WO2004105790A1 (en) 2003-06-03 2004-12-09 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
CN102940879B (zh) 2003-06-03 2017-06-06 诺沃挪第克公司 稳定化的药物肽组合物
CA2545034C (en) 2003-11-20 2013-03-05 Novo Nordisk A/S Propylene glycol-containing peptide formulations which are optimal for production and for use in injection devices
ES2442223T3 (es) 2004-08-31 2014-02-10 Novo Nordisk A/S Uso de tris(hidroximetil) aminometano para la estabilización de péptidos, polipéptidos y proteínas
PL1817048T3 (pl) 2004-11-12 2014-07-31 Novo Nordisk As Stabilne preparaty peptydów insulinotropowych
TWI762706B (zh) 2017-08-24 2022-05-01 丹麥商諾佛 儂迪克股份有限公司 Glp-1組成物及其用途
TW202140063A (zh) 2020-02-18 2021-11-01 丹麥商諾佛 儂迪克股份有限公司 醫藥配方

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0506956B1 (en) * 1990-10-19 1995-02-22 Shiseido Company Limited External preparation for skin
WO1992015607A2 (en) * 1991-03-06 1992-09-17 G.D. Searle & Co. Phenyl amidines derivatives useful as platelet aggregation inhibitors
DE69213546T2 (de) * 1991-05-13 1997-02-27 Fujisawa Pharmaceutical Co Neue Peptid-Verbindungen und Verfahren zur Herstellung davon
WO1993018058A1 (en) * 1992-03-06 1993-09-16 G.D. Searle & Co. Peptides mimics useful as platelet aggregation inhibitors
ATE168380T1 (de) * 1992-06-04 1998-08-15 Merrell Pharma Inc In der konformation beschränkte peptid analoge als wirkstoff gegen plättchenaggregation
US5354738A (en) * 1992-09-04 1994-10-11 G. D. Searle & Co. Platelet aggregation inhibitors

Also Published As

Publication number Publication date
JPH09505290A (ja) 1997-05-27
DE69422637T2 (de) 2000-06-08
DE69422637D1 (de) 2000-02-17
WO1995013825A1 (en) 1995-05-26
GR3032697T3 (en) 2000-06-30
EP0729362A1 (en) 1996-09-04
EP0729362B1 (en) 2000-01-12
PT729362E (pt) 2000-06-30
DK0729362T3 (da) 2000-05-08
CA2176462A1 (en) 1995-05-26
ATE188611T1 (de) 2000-01-15
AU8083894A (en) 1995-06-06

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