ATE188611T1 - Transdermale zusammensetzung von n-(n-(5-(4- (aminoiminomethyl)phenyl-1-oxopentyl)-l-alpha- aspartyl)-l-phenylalanin oder deren esterderivaten und ihre pharmazeutischverwendbaren salze - Google Patents
Transdermale zusammensetzung von n-(n-(5-(4- (aminoiminomethyl)phenyl-1-oxopentyl)-l-alpha- aspartyl)-l-phenylalanin oder deren esterderivaten und ihre pharmazeutischverwendbaren salzeInfo
- Publication number
- ATE188611T1 ATE188611T1 AT94931926T AT94931926T ATE188611T1 AT E188611 T1 ATE188611 T1 AT E188611T1 AT 94931926 T AT94931926 T AT 94931926T AT 94931926 T AT94931926 T AT 94931926T AT E188611 T1 ATE188611 T1 AT E188611T1
- Authority
- AT
- Austria
- Prior art keywords
- aminoiminomethyl
- oxopentyl
- aspartyl
- phenylalanine
- alpha
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 229960005190 phenylalanine Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940127218 antiplatelet drug Drugs 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 abstract 1
- 230000037317 transdermal delivery Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15504493A | 1993-11-19 | 1993-11-19 | |
| PCT/US1994/011921 WO1995013825A1 (en) | 1993-11-19 | 1994-10-24 | TRANSDERMAL COMPOSITION OF N-[N-[5-[4-(AMINOIMINOMETHYL)PHENYL]-1-OXOPENTYL]-L-α-ASPARTYL]-L-PHENYLALANINE OR ITS ESTERS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE188611T1 true ATE188611T1 (de) | 2000-01-15 |
Family
ID=22553912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94931926T ATE188611T1 (de) | 1993-11-19 | 1994-10-24 | Transdermale zusammensetzung von n-(n-(5-(4- (aminoiminomethyl)phenyl-1-oxopentyl)-l-alpha- aspartyl)-l-phenylalanin oder deren esterderivaten und ihre pharmazeutischverwendbaren salze |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0729362B1 (de) |
| JP (1) | JPH09505290A (de) |
| AT (1) | ATE188611T1 (de) |
| AU (1) | AU8083894A (de) |
| CA (1) | CA2176462A1 (de) |
| DE (1) | DE69422637T2 (de) |
| DK (1) | DK0729362T3 (de) |
| ES (1) | ES2141849T3 (de) |
| GR (1) | GR3032697T3 (de) |
| PT (1) | PT729362E (de) |
| WO (1) | WO1995013825A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1412384B1 (de) | 2001-06-28 | 2007-12-26 | Novo Nordisk A/S | Stabile formulierung von modifiziertem glp-1 |
| EP1633391B1 (de) | 2003-06-03 | 2011-10-19 | Novo Nordisk A/S | Stabilisierte pharmazeutische peptid zusammensetzungen |
| BRPI0410972C1 (pt) | 2003-06-03 | 2021-05-25 | Novo Nordisk As | método para aumentar a vida de armazenagem de uma composição farmacêutica, composição farmacêutica, e, método para tratamento de hiperglicemia |
| DK3300721T4 (da) * | 2003-11-20 | 2025-03-03 | Novo Nordisk As | Propylenglycol-holdige peptidformuleringer hvilke er optimale til fremstilling og til anvendelse i injektionsindretninger |
| PL1789434T3 (pl) | 2004-08-31 | 2014-07-31 | Novo Nordisk As | Zastosowanie tris(hydroksymetylo)aminometanu do stabilizacji peptydów, polipeptydów i białek |
| CN106137952B (zh) | 2004-11-12 | 2020-11-17 | 诺和诺德公司 | 促胰岛素肽的稳定制剂 |
| TWI847306B (zh) | 2017-08-24 | 2024-07-01 | 丹麥商諾佛 儂迪克股份有限公司 | Ｇｌｐ-１組成物及其用途 |
| BR112022013795A2 (pt) | 2020-02-18 | 2022-09-13 | Novo Nordisk As | Composição farmacêutica líquida, e, kit |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69017231T2 (de) * | 1990-10-19 | 1995-07-20 | Shiseido Co Ltd | Hautpräparat zur äusserlichen anwendung. |
| ES2065182T3 (es) * | 1991-03-06 | 1995-02-01 | Searle & Co | Derivados de fenilamidinas utiles como inhibidores de la agregacion de plaquetas. |
| DE69213546T2 (de) * | 1991-05-13 | 1997-02-27 | Fujisawa Pharmaceutical Co | Neue Peptid-Verbindungen und Verfahren zur Herstellung davon |
| WO1993018058A1 (en) * | 1992-03-06 | 1993-09-16 | G.D. Searle & Co. | Peptides mimics useful as platelet aggregation inhibitors |
| DE69319733T2 (de) * | 1992-06-04 | 1999-01-14 | Merrell Dow Pharmaceuticals Inc., Cincinnati, Ohio | In der konformation beschränkte peptid analoge als wirkstoff gegen plättchenaggregation |
| US5354738A (en) * | 1992-09-04 | 1994-10-11 | G. D. Searle & Co. | Platelet aggregation inhibitors |
-
1994
- 1994-10-24 AT AT94931926T patent/ATE188611T1/de not_active IP Right Cessation
- 1994-10-24 ES ES94931926T patent/ES2141849T3/es not_active Expired - Lifetime
- 1994-10-24 DK DK94931926T patent/DK0729362T3/da active
- 1994-10-24 WO PCT/US1994/011921 patent/WO1995013825A1/en not_active Ceased
- 1994-10-24 CA CA002176462A patent/CA2176462A1/en not_active Abandoned
- 1994-10-24 PT PT94931926T patent/PT729362E/pt unknown
- 1994-10-24 AU AU80838/94A patent/AU8083894A/en not_active Abandoned
- 1994-10-24 EP EP94931926A patent/EP0729362B1/de not_active Expired - Lifetime
- 1994-10-24 JP JP7514449A patent/JPH09505290A/ja not_active Ceased
- 1994-10-24 DE DE69422637T patent/DE69422637T2/de not_active Expired - Fee Related
-
2000
- 2000-02-18 GR GR20000400395T patent/GR3032697T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0729362A1 (de) | 1996-09-04 |
| ES2141849T3 (es) | 2000-04-01 |
| PT729362E (pt) | 2000-06-30 |
| EP0729362B1 (de) | 2000-01-12 |
| DK0729362T3 (da) | 2000-05-08 |
| WO1995013825A1 (en) | 1995-05-26 |
| CA2176462A1 (en) | 1995-05-26 |
| DE69422637T2 (de) | 2000-06-08 |
| GR3032697T3 (en) | 2000-06-30 |
| JPH09505290A (ja) | 1997-05-27 |
| DE69422637D1 (de) | 2000-02-17 |
| AU8083894A (en) | 1995-06-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |