ES2138945T3 - Sistema de suministro transdermico de farmacos para el tratamiento de enfermedades cardiacas. - Google Patents

Sistema de suministro transdermico de farmacos para el tratamiento de enfermedades cardiacas.

Info

Publication number
ES2138945T3
ES2138945T3 ES97952048T ES97952048T ES2138945T3 ES 2138945 T3 ES2138945 T3 ES 2138945T3 ES 97952048 T ES97952048 T ES 97952048T ES 97952048 T ES97952048 T ES 97952048T ES 2138945 T3 ES2138945 T3 ES 2138945T3
Authority
ES
Spain
Prior art keywords
drug
treatment
supply system
cardiac diseases
content
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97952048T
Other languages
English (en)
Other versions
ES2138945T1 (es
Inventor
Gunter Cordes
Antonino Santoro
Ivo Setnikar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rottapharm BV
Original Assignee
Rotta Research BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research BV filed Critical Rotta Research BV
Publication of ES2138945T1 publication Critical patent/ES2138945T1/es
Application granted granted Critical
Publication of ES2138945T3 publication Critical patent/ES2138945T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UN SISTEMA DE ADMINISTRACION TRANSDERMICA DE MEDICAMENTOS (SATM) PARA LA ADMINISTRACION DE NITROGLICERINA (NG) A HUMANOS, QUE COMPRENDE, DE ACUERDO CON LA SECUENCIA QUE SE INDICA A CONTINUACION, AL MENOS LAS TRES CAPAS SIGUIENTES: (I) UNA CAPA DE SOPORTE SIN MEDICAMENTO; (II) UNA CAPA DE ADHESIVO ACRILICO OPTATIVAMENTE RETICULADO, CON UN CONTENIDO DE NG Y, OPTATIVAMENTE, UN AGENTE ADHERENTE (ADHERENTE, RESINA DE ADHERENCIA O SIMPLE RESINA); Y (III) UNA CAPA ADHESIVA ACRILICA OPTATIVAMENTE RETICULADA CON UN CONTENIDO DE NG Y UN AGENTE DE ADHESIVIDAD; Y, ADEMAS, UN REVESTIMIENTO QUE PUEDE SER DESPRENDIDO.
ES97952048T 1996-12-10 1997-12-10 Sistema de suministro transdermico de farmacos para el tratamiento de enfermedades cardiacas. Expired - Lifetime ES2138945T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96119801A EP0856311A1 (en) 1996-12-10 1996-12-10 Transdermal drug delivery system for the treatment of heart diseases

Publications (2)

Publication Number Publication Date
ES2138945T1 ES2138945T1 (es) 2000-02-01
ES2138945T3 true ES2138945T3 (es) 2002-10-01

Family

ID=8223483

Family Applications (2)

Application Number Title Priority Date Filing Date
ES96119801T Pending ES2127711T1 (es) 1996-12-10 1996-12-10 Sistema de administracion transdermal de farmacos para el tratamiento de enfermedades del corazon.
ES97952048T Expired - Lifetime ES2138945T3 (es) 1996-12-10 1997-12-10 Sistema de suministro transdermico de farmacos para el tratamiento de enfermedades cardiacas.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES96119801T Pending ES2127711T1 (es) 1996-12-10 1996-12-10 Sistema de administracion transdermal de farmacos para el tratamiento de enfermedades del corazon.

Country Status (6)

Country Link
EP (2) EP0856311A1 (es)
AT (1) ATE214271T1 (es)
DE (3) DE856311T1 (es)
ES (2) ES2127711T1 (es)
GR (1) GR990300039T1 (es)
PT (1) PT944384E (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19706824C1 (de) * 1997-02-21 1998-03-26 Lohmann Therapie Syst Lts Transdermales oder topisches Plastersystem mit Polyacrylatmatrix mit verbesserten physikalischen Eigenschaften
DE19830648A1 (de) * 1998-07-09 2000-01-13 Lohmann Therapie Syst Lts Glyceroltrinitrathaltige Zusammensetzung, Verfahren zu ihrer Herstellung und ihre Verwendung
DE19940238A1 (de) 1999-08-25 2001-03-01 Lohmann Therapie Syst Lts Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59199628A (ja) * 1983-04-25 1984-11-12 Sekisui Chem Co Ltd 貼付剤
DE3315272C2 (de) * 1983-04-27 1986-03-27 Lohmann Gmbh & Co Kg, 5450 Neuwied Pharmazeutisches Produkt und Verfahren zu seiner Herstellung
UA29400C2 (uk) * 1991-06-10 2000-11-15 Шварц Фарма Аг Пластир для трансдермального введення нітрогліцерину та спосіб його виготовлення

Also Published As

Publication number Publication date
ES2127711T1 (es) 1999-05-01
DE856311T1 (de) 1999-02-25
EP0944384A1 (en) 1999-09-29
GR990300039T1 (en) 1999-12-31
DE69711075D1 (de) 2002-04-18
PT944384E (pt) 2002-06-28
EP0856311A1 (en) 1998-08-05
ATE214271T1 (de) 2002-03-15
EP0944384B1 (en) 2002-03-13
DE944384T1 (de) 2000-02-17
ES2138945T1 (es) 2000-02-01

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