ES2132163T3 - Composicion farmaceutica de liberacion controlada en forma de suspension liquida. - Google Patents

Composicion farmaceutica de liberacion controlada en forma de suspension liquida.

Info

Publication number
ES2132163T3
ES2132163T3 ES93119587T ES93119587T ES2132163T3 ES 2132163 T3 ES2132163 T3 ES 2132163T3 ES 93119587 T ES93119587 T ES 93119587T ES 93119587 T ES93119587 T ES 93119587T ES 2132163 T3 ES2132163 T3 ES 2132163T3
Authority
ES
Spain
Prior art keywords
controlled release
naproxen
liquid suspension
administration
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93119587T
Other languages
English (en)
Inventor
Giancarlo Santus
Giuseppe Bottoni
Ettore Bilato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recordati SA
Original Assignee
Recordati SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati SA filed Critical Recordati SA
Application granted granted Critical
Publication of ES2132163T3 publication Critical patent/ES2132163T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTA UNA FORMULACION FARMACEUTICA CON UN REVESTIMIENTO ENTERICO, DE LIBERACION CONTROLADA, EN SUSPENSION LIQUIDA PARA LA ADMINISTRACION DE NAPROXENO QUE CONTIENE (A) MICROGRANULOS DE NAPROXENO Y UN EXCIPIENTE; (B) CUATRO REVESTIMIENTOS SUCESIVOS DE MATERIALES HIDROFILICOS E HIDROFOBICOS POLIMERICOS, EN DONDE LOS REVESTIMIENTOS QUE PRIMERO SE APLICAN IMPARTEN UNAS PROPIEDADES DE LIBERACION CONTROLADA A DICHO NAPROXENO SEGUN UN PERFIL DE LIBERACION PREDETERMINADO; Y (C) UN VEHICULO DE ADMINISTRACION DE LIQUIDOS. ESTA COMPOSICION PERMITE LA ADMINISTRACION ORAL DE NAPROXENO A MODO DE UNA SOLA DOSIS DIARIA Y EL AJUSTE DE LA DOSIFICACION SEGUN LOS REQUISITOS DEL PACIENTE, LO QUE AYUDA A LA TOMA ORAL Y MINIMIZA LOS EFECTOS SECUNDARIOS TIPICOS DEL FARMACO.
ES93119587T 1992-12-11 1993-12-06 Composicion farmaceutica de liberacion controlada en forma de suspension liquida. Expired - Lifetime ES2132163T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922826A IT1256651B (it) 1992-12-11 1992-12-11 Composizione farmaceutica a rilascio controllato in sospensione liquida

Publications (1)

Publication Number Publication Date
ES2132163T3 true ES2132163T3 (es) 1999-08-16

Family

ID=11364448

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93119587T Expired - Lifetime ES2132163T3 (es) 1992-12-11 1993-12-06 Composicion farmaceutica de liberacion controlada en forma de suspension liquida.

Country Status (7)

Country Link
EP (1) EP0601508B1 (es)
JP (1) JPH06279274A (es)
AT (1) ATE178209T1 (es)
DE (1) DE69324214T2 (es)
ES (1) ES2132163T3 (es)
IT (1) IT1256651B (es)
SG (1) SG54207A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1270216B (it) * 1994-06-14 1997-04-29 Recordati Chem Pharm Metodo di stabilizzazione di composti biologicamente attivi mediante microgranuli ricoperti sospendibili in fluidi alimentari
GB9611328D0 (en) * 1996-05-31 1996-08-07 Zeneca Ltd Pharmaceutical compositions
DE19648576C2 (de) * 1996-11-23 1999-08-12 Lohmann Therapie Syst Lts Lutschtablette zur modifizierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt
US6004582A (en) * 1997-05-30 1999-12-21 Laboratorios Phoenix U.S.A, Inc. Multi-layered osmotic device
SE9903879D0 (sv) * 1999-10-28 1999-10-28 Ethical Pharmaceuticals Sweden Multipor food protection
FR2822834B1 (fr) 2001-04-02 2005-02-25 Flamel Tech Sa Suspension colloidale de nanoparticules a base de copolymeres amphiphile pour la vectorisation de principes actifs et leur mode de preparation
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
FR2837100B1 (fr) 2002-03-18 2004-07-23 Flamel Tech Sa Comprimes a bases de microcapsules a liberation modifiee
ATE407674T1 (de) 2002-04-09 2008-09-15 Flamel Tech Sa Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin
FR2843881B1 (fr) * 2002-09-02 2006-06-02 Flamel Tech Sa Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
ATE419840T1 (de) 2002-04-09 2009-01-15 Flamel Tech Sa Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
FR2843117B1 (fr) 2002-07-30 2004-10-15 Flamel Tech Sa Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
FR2860516B1 (fr) 2003-10-03 2006-01-13 Flamel Tech Sa Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
FR2862536B1 (fr) 2003-11-21 2007-11-23 Flamel Tech Sa Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
WO2006017159A1 (en) * 2004-07-09 2006-02-16 Drugtech Corporation Controlled phase composition technology as an improved process for protection of drugs
US9962336B2 (en) 2014-05-01 2018-05-08 Sun Pharmaceutical Industries Limited Extended release suspension compositions
US20180104197A9 (en) 2014-05-01 2018-04-19 Sun Pharmaceutical Industries Limited Extended release liquid compositions of metformin
US10258583B2 (en) * 2014-05-01 2019-04-16 Sun Pharmaceutical Industries Limited Extended release liquid compositions of guanfacine
RU2016147009A (ru) 2014-05-01 2018-06-04 Сан Фармасьютикал Индастриз Лимитед Композиции с пролонгированным высвобождением в виде суспензии
EP3174515A4 (en) 2014-07-30 2018-03-21 Sun Pharmaceutical Industries Limited Dual-chamber pack
US10238803B2 (en) 2016-05-02 2019-03-26 Sun Pharmaceutical Industries Limited Drug delivery device for pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571333A (en) * 1983-06-14 1986-02-18 Syntex (U.S.A.) Inc. Controlled release naproxen and naproxen sodium tablets
EP0178299A4 (en) * 1984-03-21 1987-04-28 Key Pharma DOSAGE FORM FOR NAPROXYN FOR PERMANENT ADMINISTRATION IN THE MOUTH.
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
IT1231410B (it) * 1987-09-22 1991-12-04 Cooperativa Farmaceutica Composizione farmaceutica antiinfiammatoria ad effetto prolungato per uso topico
GB8724763D0 (en) * 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
IT1226940B (it) * 1988-09-16 1991-02-22 Recordati Chem Pharm Sistema terapeutico a rilascio controllato per formulazioni farmaceutiche liquide
IE902829A1 (en) * 1989-08-14 1991-02-27 Eurand America Microencapsulated taste-masked water-insoluble nsaid drug¹materials
IE66933B1 (en) * 1990-01-15 1996-02-07 Elan Corp Plc Controlled absorption naproxen formulation for once-daily administration

Also Published As

Publication number Publication date
SG54207A1 (en) 1998-11-16
ITMI922826A1 (it) 1994-06-11
ATE178209T1 (de) 1999-04-15
ITMI922826A0 (it) 1992-12-11
DE69324214D1 (de) 1999-05-06
IT1256651B (it) 1995-12-12
DE69324214T2 (de) 1999-08-19
EP0601508B1 (en) 1999-03-31
EP0601508A3 (en) 1995-10-25
JPH06279274A (ja) 1994-10-04
EP0601508A2 (en) 1994-06-15

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