ES2124889T3 - Composicion distribuidora de farmacos para agentes bloqueadores alfa-adreno receptores. - Google Patents
Composicion distribuidora de farmacos para agentes bloqueadores alfa-adreno receptores.Info
- Publication number
- ES2124889T3 ES2124889T3 ES94916318T ES94916318T ES2124889T3 ES 2124889 T3 ES2124889 T3 ES 2124889T3 ES 94916318 T ES94916318 T ES 94916318T ES 94916318 T ES94916318 T ES 94916318T ES 2124889 T3 ES2124889 T3 ES 2124889T3
- Authority
- ES
- Spain
- Prior art keywords
- drug
- release
- composition
- adrene
- receivers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
EN LA INVENCION SE PRESENTA UNA COMPOSICION PARA EL SUMINISTRO ORAL DE FARMACOS QUE CONTIENE UN FARMACO DE BLOQUEO DE UN RECEPTOR DE {AL}-ADRENO QUE SE CARACTERIZA PORQUE LA COMPOSICION SE ENCUENTRA ADAPTADA PARA QUE LIBERE UNA PRIMERA PORCION DEL FARMACO EN LA PARTE SUPERIOR DEL APARATO GASTROINTESTINAL Y PARA QUE LIBERE UNA SEGUNDA PORCION DEL FARMACO MEDIANTE UNA LIBERACION PROLONGADA EN EL ILEON TERMINAL Y/O EL COLON. ESTA COMPOSICION PRESENTA UN PERFIL DE LIBERACION BIFASICO QUE MANTIENE UNOS NIVELES DE PLASMA SUFICIENTES Y ESTABLES PARA UN EFECTO TERAPEUTICO AL TIEMPO QUE SE MINIMIZAN LOS EFECTOS SECUNDARIOS AL EVITAR QUE HAY UNOS NIVELES DE PLASMA MAXIMOS ALTOS. LA LIBERACION PROLONGADA DE LA SEGUNDA Y OPCIONALMENTE DE LA PRIMERA PORCION DEL FARMACO SE CONSIGUE MEDIANTE UN SISTEMA DE LIBERACION CONTROLADA TAL COMO UNA MATRIZ DE GEL HIDROFILICA. LA LIBERACION ESPECIFICA DE LA SEGUNDA PORCION DEL FARMACO EN EL COLON SE PUEDE CONSEGUIR REVISTIENDO LAS PASTILLAS QUE CONTIENEN LA SEGUNDAPORCION CON UN REVESTIMIENTO SENSIBLE AL PH Y A LA REDUCCION-OXIDACION TAL COMO UN POLIMETILMETACRILATO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939311191A GB9311191D0 (en) | 1993-05-29 | 1993-05-29 | Controlled release drug formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2124889T3 true ES2124889T3 (es) | 1999-02-16 |
Family
ID=10736382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94916318T Expired - Lifetime ES2124889T3 (es) | 1993-05-29 | 1994-05-27 | Composicion distribuidora de farmacos para agentes bloqueadores alfa-adreno receptores. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0700285B1 (es) |
JP (1) | JPH09504779A (es) |
AT (1) | ATE171370T1 (es) |
AU (1) | AU684786B2 (es) |
CA (1) | CA2163340A1 (es) |
DE (1) | DE69413534T2 (es) |
DK (1) | DK0700285T3 (es) |
ES (1) | ES2124889T3 (es) |
FI (1) | FI955730A (es) |
GB (2) | GB9311191D0 (es) |
NO (1) | NO306759B1 (es) |
WO (1) | WO1994027582A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6166024A (en) | 1995-03-30 | 2000-12-26 | Mayo Foundation For Medical Education And Research | Use of topical azathioprine and thioguanine to treat colorectal adenomas |
FR2752737B1 (fr) * | 1996-08-29 | 1998-10-02 | Synthelabo | Comprime a liberation controlee de chlorhydrate d'alfuzosine |
US6149940A (en) * | 1996-08-29 | 2000-11-21 | Synthelabo | Tablet with controlled release of alfuzosine chlorhydrate |
UA74141C2 (uk) | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
US6749867B2 (en) | 2000-11-29 | 2004-06-15 | Joseph R. Robinson | Delivery system for omeprazole and its salts |
FR2820318B1 (fr) * | 2001-02-08 | 2005-12-23 | Ellipse Pharmaceuticals | Procede de fabrication d'un comprime flottant incluant un principe actif et comprime obtenu |
FR2820319B3 (fr) * | 2001-02-08 | 2003-12-05 | Ellipse Pharmaceuticals | Procede de fabrication d'un comprime flottant incluant de l'alfuzosine et comprime obtenu |
EP1366761A4 (en) * | 2001-02-13 | 2004-04-21 | Taisho Pharmaceutical Co Ltd | GEL PREPARATIONS FOR INTERNAL USE |
BR0315569A (pt) * | 2002-10-22 | 2005-08-30 | Ranbaxy Lab Ltd | Apresentação farmacêutica de liberação prolongada contendo alfuzosina |
WO2007080509A2 (en) | 2006-01-12 | 2007-07-19 | Wockhardt Ltd | Sustained release compositions of alfuzosin |
US20070292505A1 (en) * | 2006-06-15 | 2007-12-20 | Abrika Pharmaceuticals, Inc. | Controlled release alfuzosin hydrochloride formulation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1101649B (it) * | 1978-12-15 | 1985-10-07 | Lehner Ag | Composizione farmaceutica ad azione prolungata contenente acidi biliari |
FR2477015A1 (fr) * | 1980-03-03 | 1981-09-04 | Fabre Sa Pierre | Composition pharmaceutique a base d'un alcaloide de l'ergot de seigle, a activite regulatrice sur le tonus vasculaire |
US4931285A (en) * | 1988-04-28 | 1990-06-05 | Alza Corporation | Aqueous based pharmaceutical coating composition for dosage forms |
DE3822095A1 (de) * | 1988-06-30 | 1990-01-04 | Klinge Co Chem Pharm Fab | Neue arzneimittelformulierung sowie verfahren zu deren herstellung |
-
1993
- 1993-05-29 GB GB939311191A patent/GB9311191D0/en active Pending
-
1994
- 1994-05-27 ES ES94916318T patent/ES2124889T3/es not_active Expired - Lifetime
- 1994-05-27 DE DE69413534T patent/DE69413534T2/de not_active Expired - Lifetime
- 1994-05-27 EP EP94916318A patent/EP0700285B1/en not_active Expired - Lifetime
- 1994-05-27 WO PCT/GB1994/001158 patent/WO1994027582A1/en active IP Right Grant
- 1994-05-27 CA CA002163340A patent/CA2163340A1/en not_active Abandoned
- 1994-05-27 AT AT94916318T patent/ATE171370T1/de active
- 1994-05-27 GB GB9523191A patent/GB2292315B/en not_active Expired - Lifetime
- 1994-05-27 DK DK94916318T patent/DK0700285T3/da active
- 1994-05-27 JP JP7500403A patent/JPH09504779A/ja active Pending
- 1994-05-27 AU AU68020/94A patent/AU684786B2/en not_active Expired
-
1995
- 1995-11-14 NO NO954583A patent/NO306759B1/no not_active IP Right Cessation
- 1995-11-28 FI FI955730A patent/FI955730A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
GB9523191D0 (en) | 1996-01-17 |
DK0700285T3 (da) | 1999-02-15 |
EP0700285B1 (en) | 1998-09-23 |
GB2292315A (en) | 1996-02-21 |
JPH09504779A (ja) | 1997-05-13 |
NO306759B1 (no) | 1999-12-20 |
EP0700285A1 (en) | 1996-03-13 |
GB9311191D0 (en) | 1993-07-14 |
DE69413534T2 (de) | 1999-03-18 |
FI955730A (fi) | 1996-01-26 |
GB2292315B (en) | 1997-04-02 |
ATE171370T1 (de) | 1998-10-15 |
CA2163340A1 (en) | 1994-12-08 |
WO1994027582A1 (en) | 1994-12-08 |
DE69413534D1 (de) | 1998-10-29 |
AU684786B2 (en) | 1998-01-08 |
NO954583D0 (no) | 1995-11-14 |
AU6802094A (en) | 1994-12-20 |
FI955730A0 (fi) | 1995-11-28 |
NO954583L (no) | 1995-11-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT984774E (pt) | Microesferas de libertacao controlada, com retencao gastrica, para uma administracao de drogas melhorada | |
EE9700241A (et) | Farmatseutiline kompositsioon transdermaalseks manustamiseks | |
ES2124889T3 (es) | Composicion distribuidora de farmacos para agentes bloqueadores alfa-adreno receptores. | |
FI954228A (fi) | Infuusiolaite hoitoaineen jaksottaista tai jatkuvaa antamista varten | |
FI954767A (fi) | Lipofiilisiä lääkeaineita sisältävä farmaseuttinen koostumus | |
DK0799028T3 (da) | Formulering med styret afgift til tungt opløselige basiske lægemidler | |
NO961136D0 (no) | Farmasöytisk formuleringsgrunnlag for nano-suspensjoner | |
ID29994A (id) | Komposisi farmasi untuk melawan ccr5 terdiri dari turunan anilida | |
DE60233898D1 (de) | Transdermales therapeutisches system für parkinson-krankheit mit hohen rotigotin-plasmaspiegeln | |
NO953278L (no) | Fremgangsmåter for in vivo-levering av biologisk aktive stoffer og sammensetninger som er nyttige for dette | |
CO5130022A1 (es) | Sistema de entrega controlado de droga administrado oralmente, que provee control temporal y espacial | |
AU2084801A (en) | Antiviral medication | |
BR9610983A (pt) | Formas estáveis de administração farmacêuticas contendo paratormônio | |
PT1017392E (pt) | Formulacao de medicamento com libertacao controlada do principio activo | |
NL193820B (nl) | Vaste farmaceutische doseringsvorm voor orale toediening van Ibuprofen. | |
AU7291996A (en) | Transdermal therapeutic system (tts) for the administration of drugs for treatment of drug dependency or drug addiction | |
HUP9901260A3 (en) | Optically active phenylpyrimidine derivative as analgesic agent, process for producing it, pharmaceutical composition containing it and its intermediate | |
HUP0201405A2 (en) | Pharmaceutical composition for therapeutic use of melatonin | |
PT1151746E (pt) | Microcapsulas para libertacao sustentada de medicamentos | |
PL325242A1 (en) | Method of obtaining solid drug administration forms for very low dosage drugs | |
LT99148A (en) | Drug delivery devices and pharmaceutical composition for treatment wasting syndromes | |
IL115861A0 (en) | Pharmaceutical formulation for controlled release of melatonin | |
SI0859595T1 (en) | Therapeutic preparation for the transdermal administration of active substances | |
TH35426A (th) | สารผสม | |
PL301249A1 (en) | Application of iphosphamide as an anticarcinogenic drug |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 700285 Country of ref document: ES |