ES2131039T3 - Procedimiento para la fabricacion de aplicadores transdermicos de medicamentos. - Google Patents

Procedimiento para la fabricacion de aplicadores transdermicos de medicamentos.

Info

Publication number
ES2131039T3
ES2131039T3 ES88108838T ES88108838T ES2131039T3 ES 2131039 T3 ES2131039 T3 ES 2131039T3 ES 88108838 T ES88108838 T ES 88108838T ES 88108838 T ES88108838 T ES 88108838T ES 2131039 T3 ES2131039 T3 ES 2131039T3
Authority
ES
Spain
Prior art keywords
electrically
drug
electrodes
deposit
battery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88108838T
Other languages
English (en)
Inventor
Dan Sibalis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Drug Delivery Systems Inc
Original Assignee
Drug Delivery Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/058,527 external-priority patent/US4883457A/en
Application filed by Drug Delivery Systems Inc filed Critical Drug Delivery Systems Inc
Application granted granted Critical
Publication of ES2131039T3 publication Critical patent/ES2131039T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)

Abstract

ADAPTADORES PARA LA DISTRIBUCION ELECTROFORETICA Y / O ELECTROOSMETICA DE UN MEDICAMENTE A TRAVES DE LA PIEL Y DENTRO DE LA SANGRE DE UN PACIENTE. CADA APLICADOR INCLUYE DOS ELECTRODOS EN CONTACTO ELECTRICO CON LA PIEL CON AL MENOS EN UNO DE LOS ELECTRODOS UN DEPOSITO DE DROGA, AL MENOS UNA BATERIA, UN FLEXIBLE, NO CONDUCTOR SUBSTRATO QUE TIENE UNA CAPA CONDUCTORA ELECTRICAMENTE QUE SE EXTIENDE A CONTADOS ELECTRICOS CON CADA ELECTRODO Y A LAS TERMINALES DE LA BATERIA, EL SUBSTRATO ES ENCERRADO DENTRO DE AL MENOS DOS CAPAS, Y UNA CUBIERTA PARA EL DEPOSITO DE DROGA. EL SUBSTRATO FLEXIBLE Y LAS AREAS CUBIERTAS CONDUCTORAS FORMAN UNA SIMPLE, SUBSTANCIALMENTE LLAMA, ELEMENTO FLEXIBLE. EL APLICADOR PUEDE INCLUIR UNA PLURALIDAD DE DEPOSITOS DE DROGA SEPARADOS CADA UNO ACTUANDO COMO UN ELECTRODO. AL MENOS UNA BATERIA ES CONECTADA EN SERIE CON LOS ELECTRODOS DEL DEPOSITO DE DROGA. EL SUBSTRATO FLEXIBLE TIENE OPUESTAS SUPERFICIES LLANAS, LAS AREAS CUBIERTAS CONDUCTORES ELECTRICAMENTE SON ELECTRICAMENTE AREAS CUBIERTAS EN LAS SUPERFICIES LLANAS. LA CONEXION ELECTRICA ENTRE EL AREA PROTEGIDA CONDUCTORA EN LA PROXIMIDAD DE CADA DEPOSITO ES PROVISTA POR MATERIAL CONDUCTOR ELECTRICAMENTE QUE SE EXTIENDE A TRAVES DE UN SOLO AGUJERO O UNA PLURALIDAD DE AGUJEROS QUE SE EXTIENDEN ENTRE LAS SUPERFICIES OPUESTAS DEL SUBSTRATO.
ES88108838T 1987-06-05 1988-06-02 Procedimiento para la fabricacion de aplicadores transdermicos de medicamentos. Expired - Lifetime ES2131039T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/058,527 US4883457A (en) 1983-08-18 1987-06-05 Disposable and/or replenishable transdermal drug applicators and methods of manufacturing same
US07/169,385 US4865582A (en) 1987-06-05 1988-03-17 Disposable transdermal drug applicators

Publications (1)

Publication Number Publication Date
ES2131039T3 true ES2131039T3 (es) 1999-07-16

Family

ID=26737714

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88108838T Expired - Lifetime ES2131039T3 (es) 1987-06-05 1988-06-02 Procedimiento para la fabricacion de aplicadores transdermicos de medicamentos.

Country Status (10)

Country Link
US (1) US4865582A (es)
EP (1) EP0293893B1 (es)
JP (2) JP2632367B2 (es)
AR (1) AR246025A1 (es)
AT (1) ATE176873T1 (es)
AU (1) AU618734B2 (es)
BR (1) BR8802677A (es)
CA (1) CA1322921C (es)
DE (1) DE3856306T2 (es)
ES (1) ES2131039T3 (es)

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US5651768A (en) * 1983-08-18 1997-07-29 Drug Delivery Systems, Inc. Transdermal drug applicator and electrodes therefor
US5605536A (en) * 1983-08-18 1997-02-25 Drug Delivery Systems Inc. Transdermal drug applicator and electrodes therefor
US5135477A (en) * 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US6956032B1 (en) 1986-04-18 2005-10-18 Carnegie Mellon University Cyanine dyes as labeling reagents for detection of biological and other materials by luminescence methods
US5746711A (en) * 1987-01-05 1998-05-05 Drug Delivery Systems, Inc. Programmable control and mounting system for transdermal drug applicator
KR970011449B1 (ko) * 1988-01-29 1997-07-11 더 리전트 오브 디 유니버시티 오브 캘리포니아 이온전기 영동형 비침입 검체 채취 또는 이송 장치 및 방법
US5362307A (en) * 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
IL86076A (en) * 1988-04-14 1992-12-01 Inventor S Funding Corp Ltd Transdermal drug delivery device
US4950229A (en) * 1989-09-25 1990-08-21 Becton, Dickinson And Company Apparatus for an electrode used for iontophoresis
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
AU647103B2 (en) * 1990-03-30 1994-03-17 Alza Corporation Iontophoretic delivery device
US6004309A (en) 1990-03-30 1999-12-21 Alza Corporation Method and apparatus for controlled environment electrotransport
US5207752A (en) * 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
US5087241A (en) * 1990-07-24 1992-02-11 Empi, Inc. Iontophoresis electrode with reservoir and injection site
US5037381A (en) * 1990-07-27 1991-08-06 Bock C Randolph Electrically assisted transdermal transport device and method for renewing the device
US5312326A (en) * 1992-06-02 1994-05-17 Alza Corporation Iontophoretic drug delivery apparatus
EP0751801B1 (en) * 1992-06-02 1997-11-26 Alza Corporation Electrotransport drug delivery device
US6317629B1 (en) * 1992-06-02 2001-11-13 Alza Corporation Iontophoretic drug delivery apparatus
US5380272A (en) * 1993-01-28 1995-01-10 Scientific Innovations Ltd. Transcutaneous drug delivery applicator
US5445609A (en) * 1993-05-28 1995-08-29 Alza Corporation Electrotransport agent delivery device having a disposable component and a removable liner
FR2709670B1 (fr) * 1993-09-10 1995-10-20 Asulab Sa Dispositif en trois modules pour l'administration transdermique de médicaments par électrophorèse ou iontophorèse.
US5415629A (en) * 1993-09-15 1995-05-16 Henley; Julian L. Programmable apparatus for the transdermal delivery of drugs and method
US5387189A (en) * 1993-12-02 1995-02-07 Alza Corporation Electrotransport delivery device and method of making same
WO1996010442A1 (en) * 1994-09-30 1996-04-11 Becton Dickinson And Company Improved iontophoretic drug delivery device
US5498235A (en) * 1994-09-30 1996-03-12 Becton Dickinson And Company Iontophoresis assembly including patch/controller attachment
US5562607A (en) * 1995-01-18 1996-10-08 Alza Corporation Electrotransport device having reusable controller power saver
US5954685A (en) * 1996-05-24 1999-09-21 Cygnus, Inc. Electrochemical sensor with dual purpose electrode
AU3404097A (en) * 1996-06-19 1998-01-07 Becton Dickinson & Company Iontophoretic delivery of cell adhesion inhibitors
IE970557A1 (en) * 1996-12-26 1998-07-01 Elan Med Tech Device for the delivery of a substance to a subject and¹improved electrode assembly
US5991655A (en) * 1997-03-03 1999-11-23 Drug Delivery Systems, Inc. Iontophoretic drug delivery device and method of manufacturing the same
US6078842A (en) * 1997-04-08 2000-06-20 Elan Corporation, Plc Electrode and iontophoretic device and method
JPH11239621A (ja) * 1998-02-25 1999-09-07 Hisamitsu Pharmaceut Co Inc イオントフォレーシス装置
US6148231A (en) 1998-09-15 2000-11-14 Biophoretic Therapeutic Systems, Llc Iontophoretic drug delivery electrodes and method
US6477410B1 (en) 2000-05-31 2002-11-05 Biophoretic Therapeutic Systems, Llc Electrokinetic delivery of medicaments
US6792306B2 (en) 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US7127285B2 (en) 1999-03-12 2006-10-24 Transport Pharmaceuticals Inc. Systems and methods for electrokinetic delivery of a substance
FI106364B (fi) 1999-06-21 2001-01-31 Lehtoluoto Eeva Liisa Ihonpuhdistuslaite
AT411150B (de) * 2001-05-25 2003-10-27 Nova Technical Res Gmbh Einrichtung zum einbringen von stoffen
PL205827B1 (pl) 2001-10-31 2010-05-31 Tti Ellebeau Urządzenie do jontoforezy
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
US7749194B2 (en) 2005-02-01 2010-07-06 Intelliject, Inc. Devices, systems, and methods for medicament delivery
US7731686B2 (en) * 2005-02-01 2010-06-08 Intelliject, Inc. Devices, systems and methods for medicament delivery
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
RU2008117153A (ru) * 2005-09-30 2009-11-10 ТиТиАй ЭЛЛЕБО, ИНК. (JP) Аппарат для ионтофореза, доставляющий множество активных агентов к биологическим барьерам
CN104138634B (zh) 2006-04-13 2016-09-07 梯瓦制药国际有限责任公司 递送抗偏头痛化合物的透皮方法和系统
WO2008091838A2 (en) 2007-01-22 2008-07-31 Intelliject, Inc. Medical injector with compliance tracking and monitoring
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
WO2008157481A1 (en) * 2007-06-15 2008-12-24 Transport Pharmaceuticals, Inc. Method and system for mitigating current concentration in electrokinetic drug delivery
ES2454974T3 (es) * 2007-06-27 2014-04-14 The General Hospital Corporation Aparato para la inhibición óptica de la terapia fotodinámica
SG183726A1 (en) 2007-08-14 2012-09-27 Hutchinson Fred Cancer Res Needle array assembly and method for delivering therapeutic agents
US20110160640A1 (en) * 2008-01-18 2011-06-30 Yanaki Jamal S Operation management of active transdermal medicament patch
US8862223B2 (en) * 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
EP2768576B1 (en) * 2011-10-19 2018-07-25 HTK Enterprises, Inc. Electrode apparatus with interfitting elements and a method for its manufacture including stamping
EP2771043A4 (en) 2011-10-28 2015-04-29 Presage Biosciences Inc METHODS OF DRUG DELIVERY
GB2523512A (en) 2012-12-27 2015-08-26 Kaleo Inc Devices, systems and methods for locating and interacting with medicament delivery systems
WO2015187377A1 (en) * 2014-06-02 2015-12-10 Avery Dennison Corporation Sensor patches
JP6221195B2 (ja) 2014-12-08 2017-11-01 株式会社プロキダイ 生体用電極
FR3034017B1 (fr) * 2015-03-24 2018-11-02 Feeligreen Matrice polymerique adhesive pour iontophorese et dispositif pour l'iontophorese comprenant ladite matrice
US10332623B2 (en) 2017-01-17 2019-06-25 Kaleo, Inc. Medicament delivery devices with wireless connectivity and event detection
CN110548219A (zh) * 2018-06-01 2019-12-10 安徽舒源妇幼用品有限公司 一种成人护理垫及其加工方法
US11929160B2 (en) 2018-07-16 2024-03-12 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection

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FR2263792A1 (en) * 1974-03-12 1975-10-10 Bondivenne Jean Ionotherapy current generator - comprises thin flexible bag giving percutaneous medicament penetration
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US4267840A (en) * 1979-01-08 1981-05-19 Johnson & Johnson Electrosurgical grounding pad
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EP0092015A1 (fr) * 1982-04-16 1983-10-26 Roland Brodard Dispositif d'ionisation
US4557723A (en) * 1983-08-18 1985-12-10 Drug Delivery Systems Inc. Applicator for the non-invasive transcutaneous delivery of medicament
US4731926A (en) * 1985-02-19 1988-03-22 Drug Delivery Systems Inc. Method of manufacturing disposable and/or replenishable transdermal drug applicators
US4622031A (en) * 1983-08-18 1986-11-11 Drug Delivery Systems Inc. Indicator for electrophoretic transcutaneous drug delivery device
JPH0239267B2 (ja) * 1984-06-12 1990-09-04 Intaa Noba Kk Inionchunyushikichiryosochi
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Also Published As

Publication number Publication date
JPH08238325A (ja) 1996-09-17
EP0293893B1 (en) 1999-02-24
EP0293893A3 (en) 1989-03-22
EP0293893A2 (en) 1988-12-07
AU618734B2 (en) 1992-01-09
AR246025A1 (es) 1994-03-30
BR8802677A (pt) 1988-12-27
ATE176873T1 (de) 1999-03-15
CA1322921C (en) 1993-10-12
JP2632367B2 (ja) 1997-07-23
AU1655088A (en) 1988-12-08
DE3856306T2 (de) 1999-09-30
DE3856306D1 (de) 1999-04-01
JPS63317162A (ja) 1988-12-26
US4865582A (en) 1989-09-12

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