ES2129430T3 - Analogos superactivos del factor liberador de la hormona del crecimiento. - Google Patents
Analogos superactivos del factor liberador de la hormona del crecimiento.Info
- Publication number
- ES2129430T3 ES2129430T3 ES92303717T ES92303717T ES2129430T3 ES 2129430 T3 ES2129430 T3 ES 2129430T3 ES 92303717 T ES92303717 T ES 92303717T ES 92303717 T ES92303717 T ES 92303717T ES 2129430 T3 ES2129430 T3 ES 2129430T3
- Authority
- ES
- Spain
- Prior art keywords
- grf
- provides
- analogs
- growth hormone
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000038461 Growth Hormone-Releasing Hormone Human genes 0.000 title abstract 9
- 101710142969 Somatoliberin Proteins 0.000 title abstract 9
- 239000000095 Growth Hormone-Releasing Hormone Substances 0.000 title abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 102000018997 Growth Hormone Human genes 0.000 abstract 2
- 108010051696 Growth Hormone Proteins 0.000 abstract 2
- 239000000122 growth hormone Substances 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
- Steering-Linkage Mechanisms And Four-Wheel Steering (AREA)
- Oscillators With Electromechanical Resonators (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Electrotherapy Devices (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Farming Of Fish And Shellfish (AREA)
Abstract
LA INVENCION SUMINISTRA UNA HORMONA DEL CRECIMIENTO MODIFICADA EN EL AMINO TERMINAL QUE LIBERA ANALOGOS (GRF) DE UNA POTENCIA Y ACTIVIDAD SUPERIORES CUANDO SE COMPARA CON EL GRF NATIVO O LOS ANALOGOS DEL GRF PREVIAMENTE DESCRITOS. LA INVENCION TAMBIEN SUMINISTRA ANALOGOS DEL GRF MODIFICADOS EN EL AMINO TERMINAL QUE COMPRENDE PEPTIDOS DEL GRF QUE INCORPORAN MODIFICACIONES DEL ACIDO AMINO SELECCIONADOS A PARTIR DE LAS FORMAS QUE SE PRODUCEN DE MODO NATURAL DE LOS PEPTIDOS DEL GRF. SE DESCRIBEN ANALOGOS SUPERIORES DE LAS ESPECIES BOBINA, PORCINA, HUMANA Y OTRAS ESPECIES. LA INVENCION TAMBIEN SUMINISTRA UN METODO PARA PROMOVER LA LIBERACION DE LA HORMONA DEL CRECIMIENTO USANDO LA HORMONA DE LA INVENCION. TAMBIEN SE SUMINISTRAN FORMULAS FARMACEUTICAS DE LOS COMPUESTOS DE LA INVENCION. LA INVENCION TAMBIEN SUMINISTRA METODOS DE TRATAMIENTOS PARA VARIAS ENFERMEDADES QUE RESULTAN DE NIVELES INSUFICIENTES DE LA HORMONA DEL CRECIMIENTO USANDO ESTOS COMPUESTOS. LA INVENCION TAMBIEN SUMINISTRA UN METODO PARA AUMENTAR LA MASA MUSCULAR EN MAMIFEROS MEDIANTE LA ADMINISTRACION DE ESTOS COMPUESTOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69209091A | 1991-04-26 | 1991-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2129430T3 true ES2129430T3 (es) | 1999-06-16 |
Family
ID=24779221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92303717T Expired - Lifetime ES2129430T3 (es) | 1991-04-26 | 1992-04-24 | Analogos superactivos del factor liberador de la hormona del crecimiento. |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0511003B1 (es) |
| JP (1) | JPH05279388A (es) |
| KR (1) | KR100233804B1 (es) |
| CN (1) | CN1068123A (es) |
| AT (1) | ATE178073T1 (es) |
| AU (1) | AU1513292A (es) |
| BR (1) | BR9201512A (es) |
| CA (1) | CA2067304A1 (es) |
| CZ (1) | CZ285567B6 (es) |
| DE (1) | DE69228717T2 (es) |
| DK (1) | DK0511003T3 (es) |
| ES (1) | ES2129430T3 (es) |
| FI (1) | FI921855A (es) |
| GR (1) | GR3030459T3 (es) |
| HU (1) | HUT64589A (es) |
| IE (1) | IE921338A1 (es) |
| IL (1) | IL101620A (es) |
| MX (1) | MX9201878A (es) |
| NO (1) | NO921595L (es) |
| NZ (1) | NZ242459A (es) |
| SG (1) | SG46364A1 (es) |
| TW (1) | TW360661B (es) |
| YU (1) | YU44292A (es) |
| ZA (1) | ZA922746B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5453418A (en) * | 1988-03-07 | 1995-09-26 | Eli Lilly And Company | Ractopamine and growth hormone combinations |
| JPH07509128A (ja) * | 1992-07-13 | 1995-10-12 | バイオネブラスカ・インコーポレーテッド | 組換型ポリペプチドの修飾方法 |
| CA2222068C (en) * | 1995-05-26 | 2007-04-10 | Theratechnologies Inc. | Chimeric fatty body-pro-grf analogs with increased biological potency |
| EP0766966A3 (en) * | 1995-09-08 | 2001-02-28 | Eli Lilly And Company | Method of treating insulin resistance |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4628043A (en) * | 1983-04-26 | 1986-12-09 | The Salk Institute For Biological Studies | Hypothalamic GRF agonists |
| US4626523A (en) * | 1983-09-13 | 1986-12-02 | The Salk Institute For Biological Studies | GRF analogs II |
| US4528190A (en) * | 1983-10-25 | 1985-07-09 | The Salk Institute For Biological Studies | GRF Analogs IV |
| CA1271600A (en) * | 1985-01-07 | 1990-07-10 | David Howard Coy | Growth hormone-releasing peptides and method of treating mammals therewith |
-
1992
- 1992-04-14 ZA ZA922746A patent/ZA922746B/xx unknown
- 1992-04-16 IL IL10162092A patent/IL101620A/en not_active IP Right Cessation
- 1992-04-21 CZ CS921211A patent/CZ285567B6/cs not_active IP Right Cessation
- 1992-04-23 MX MX9201878A patent/MX9201878A/es unknown
- 1992-04-23 NZ NZ242459A patent/NZ242459A/en unknown
- 1992-04-24 KR KR1019920006975A patent/KR100233804B1/ko not_active IP Right Cessation
- 1992-04-24 BR BR929201512A patent/BR9201512A/pt not_active Application Discontinuation
- 1992-04-24 CN CN92104215A patent/CN1068123A/zh active Pending
- 1992-04-24 DK DK92303717T patent/DK0511003T3/da active
- 1992-04-24 SG SG1996003583A patent/SG46364A1/en unknown
- 1992-04-24 FI FI921855A patent/FI921855A/fi unknown
- 1992-04-24 DE DE69228717T patent/DE69228717T2/de not_active Expired - Fee Related
- 1992-04-24 YU YU44292A patent/YU44292A/sh unknown
- 1992-04-24 AU AU15132/92A patent/AU1513292A/en not_active Abandoned
- 1992-04-24 NO NO92921595A patent/NO921595L/no unknown
- 1992-04-24 AT AT92303717T patent/ATE178073T1/de active
- 1992-04-24 EP EP92303717A patent/EP0511003B1/en not_active Expired - Lifetime
- 1992-04-24 ES ES92303717T patent/ES2129430T3/es not_active Expired - Lifetime
- 1992-04-24 IE IE133892A patent/IE921338A1/en unknown
- 1992-04-24 JP JP4106569A patent/JPH05279388A/ja active Pending
- 1992-04-27 HU HU9201399A patent/HUT64589A/hu unknown
- 1992-04-27 CA CA002067304A patent/CA2067304A1/en not_active Abandoned
- 1992-05-14 TW TW081103757A patent/TW360661B/zh active
-
1999
- 1999-06-09 GR GR990401532T patent/GR3030459T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ242459A (en) | 1993-12-23 |
| FI921855A (fi) | 1992-10-27 |
| IL101620A (en) | 1996-08-04 |
| TW360661B (en) | 1999-06-11 |
| CA2067304A1 (en) | 1992-10-27 |
| ATE178073T1 (de) | 1999-04-15 |
| KR920019817A (ko) | 1992-11-20 |
| BR9201512A (pt) | 1992-12-01 |
| NO921595D0 (no) | 1992-04-24 |
| NO921595L (no) | 1992-10-27 |
| GR3030459T3 (en) | 1999-10-29 |
| IE921338A1 (en) | 1992-11-04 |
| AU690264B2 (en) | 1998-04-23 |
| SG46364A1 (en) | 1998-02-20 |
| DK0511003T3 (da) | 1999-05-25 |
| MX9201878A (es) | 1992-10-01 |
| AU1513292A (en) | 1992-10-29 |
| EP0511003B1 (en) | 1999-03-24 |
| AU2333495A (en) | 1995-09-14 |
| HU9201399D0 (en) | 1992-08-28 |
| YU44292A (sh) | 1994-06-24 |
| DE69228717D1 (de) | 1999-04-29 |
| CS121192A3 (en) | 1992-11-18 |
| JPH05279388A (ja) | 1993-10-26 |
| HUT64589A (en) | 1994-01-28 |
| CZ285567B6 (cs) | 1999-09-15 |
| IL101620A0 (en) | 1992-12-30 |
| KR100233804B1 (ko) | 1999-12-01 |
| CN1068123A (zh) | 1993-01-20 |
| ZA922746B (en) | 1992-12-30 |
| FI921855A0 (fi) | 1992-04-24 |
| EP0511003A1 (en) | 1992-10-28 |
| DE69228717T2 (de) | 1999-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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