ES2126652T3 - Metodo de citodiagnostico utilizando la alstonina como marcador selectivo y kit de diagnostico conteniendo dicho marcador. - Google Patents
Metodo de citodiagnostico utilizando la alstonina como marcador selectivo y kit de diagnostico conteniendo dicho marcador.Info
- Publication number
- ES2126652T3 ES2126652T3 ES93916038T ES93916038T ES2126652T3 ES 2126652 T3 ES2126652 T3 ES 2126652T3 ES 93916038 T ES93916038 T ES 93916038T ES 93916038 T ES93916038 T ES 93916038T ES 2126652 T3 ES2126652 T3 ES 2126652T3
- Authority
- ES
- Spain
- Prior art keywords
- marker
- alstonine
- pct
- cytodiagnostic
- selective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- WYTGDNHDOZPMIW-RCBQFDQVSA-N alstonine Chemical compound C1=CC2=C3C=CC=CC3=NC2=C2N1C[C@H]1[C@H](C)OC=C(C(=O)OC)[C@H]1C2 WYTGDNHDOZPMIW-RCBQFDQVSA-N 0.000 title abstract 4
- 239000003550 marker Substances 0.000 title abstract 3
- 238000009007 Diagnostic Kit Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- QVBOOBQEGOUUGN-RCBQFDQVSA-N alstonine Chemical compound C1=C[CH]C2=NC3=C(C[C@@H]4C(C(=O)OC)=CO[C@@H](C)[C@@H]4C4)[N+]4=CC=C3C2=C1 QVBOOBQEGOUUGN-RCBQFDQVSA-N 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 239000000032 diagnostic agent Substances 0.000 abstract 2
- 229940039227 diagnostic agent Drugs 0.000 abstract 2
- 208000031404 Chromosome Aberrations Diseases 0.000 abstract 1
- 231100000005 chromosome aberration Toxicity 0.000 abstract 1
- 230000002559 cytogenic effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 230000002980 postoperative effect Effects 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
- 230000001173 tumoral effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/816—Alkaloids, amphetamines, and barbiturates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
COMPOSICION DE ALSTONINA PARA UTILIZACION COMO MARCADOR SELECTIVO DE CELULAS TUMORALES Y/O ABERRACIONES CROMOSOMICAS, PARA LA DETECCION DE ESTAS MEDIANTE LA MEDICION DE FLUORESCENCIA EN UNOS 375 NM. UTILIZACION PARA LA OBTENCION DE UN REACTIVO DE DIAGNOSTICO, DESTINADO A LA DETECCION DE ENFERMEDADES TUMORALES Y EN CITOGENETICA. APLICACION A LOS DIAGNOSTICOS PRE, DURANTE Y POST
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9209283A FR2694193B1 (fr) | 1992-07-28 | 1992-07-28 | Méthode de cytodiagnostic utilisant l'alstonine comme marqueur sélectif et kit de diagnostic contenant ce marqueur. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2126652T3 true ES2126652T3 (es) | 1999-04-01 |
Family
ID=9432327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93916038T Expired - Lifetime ES2126652T3 (es) | 1992-07-28 | 1993-07-26 | Metodo de citodiagnostico utilizando la alstonina como marcador selectivo y kit de diagnostico conteniendo dicho marcador. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5567593A (es) |
| EP (1) | EP0605701B1 (es) |
| JP (1) | JPH07503323A (es) |
| AT (1) | ATE172028T1 (es) |
| BR (1) | BR9305588A (es) |
| CA (1) | CA2120002C (es) |
| DE (1) | DE69321454T2 (es) |
| ES (1) | ES2126652T3 (es) |
| FR (1) | FR2694193B1 (es) |
| WO (1) | WO1994002829A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136540A (en) | 1994-10-03 | 2000-10-24 | Ikonisys Inc. | Automated fluorescence in situ hybridization detection of genetic abnormalities |
| WO2000025782A1 (en) * | 1998-10-29 | 2000-05-11 | Merck & Co., Inc. | Dihydropyridinones and pyrrolinones useful as alpha 1a adrenoceptor antagonists |
| WO2001035078A1 (en) * | 1999-11-09 | 2001-05-17 | Raytheon Company | Method and apparatus for performing cell analysis based on simultaneous multiple marker emissions from neoplasia (casmmen) |
| US6956695B2 (en) | 2001-03-19 | 2005-10-18 | Ikonisys, Inc. | System and method for increasing the contrast of an image produced by an epifluorescence microscope |
| KR20030046063A (ko) * | 2001-12-04 | 2003-06-12 | 이성문 | 음식물 찌꺼기와 식물성 찌꺼기를 이용하여 칼슘석회석과(Caco3) 마그네슘(MGO) 장석운모 바이오와재오라이트석 가루를 60매시로 배합하여 숙성시킨칼슘석회질 유기질 비료 제조방법. |
| WO2006053680A1 (en) * | 2004-11-19 | 2006-05-26 | Nowicky Wassili | Ex vivo cancer diagnostic method |
| WO2006053649A1 (en) * | 2004-11-19 | 2006-05-26 | Nowicky Wassili | Method for the detection of cancer |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4160019A (en) * | 1973-06-25 | 1979-07-03 | Bjorklund Knut B | Detection of cancer associated polypeptide antigen and preparation of antibodies thereto |
| FR2419725A1 (fr) * | 1978-03-13 | 1979-10-12 | Beljanski Mirko | Serpentine, alstonine et sempervirine, medicaments inhibant specifiquement les cellules cancereuses et tumorales |
| FR2439783A1 (fr) * | 1978-03-13 | 1980-05-23 | Beljanski Mirko | Procede d'extraction de la serpentine et de l'alstonine |
| ATE15971T1 (de) * | 1981-03-11 | 1985-10-15 | Mirko Beljanski | Serpentin, alstonin und sempervirin, medikamente, die die tumor- und krebszellen spezifisch hemmen. |
| US4649151A (en) * | 1982-09-27 | 1987-03-10 | Health Research, Inc. | Drugs comprising porphyrins |
| AT387860B (de) * | 1985-09-16 | 1989-03-28 | Optical Sensing Technology | Verfahren und vorrichtung zur tumordiagnose mittels sera |
| US5283255A (en) * | 1987-01-20 | 1994-02-01 | The University Of British Columbia | Wavelength-specific cytotoxic agents |
-
1992
- 1992-07-28 FR FR9209283A patent/FR2694193B1/fr not_active Expired - Fee Related
-
1993
- 1993-07-26 BR BR9305588A patent/BR9305588A/pt not_active IP Right Cessation
- 1993-07-26 CA CA002120002A patent/CA2120002C/en not_active Expired - Fee Related
- 1993-07-26 EP EP93916038A patent/EP0605701B1/fr not_active Expired - Lifetime
- 1993-07-26 ES ES93916038T patent/ES2126652T3/es not_active Expired - Lifetime
- 1993-07-26 AT AT93916038T patent/ATE172028T1/de not_active IP Right Cessation
- 1993-07-26 US US08/196,165 patent/US5567593A/en not_active Expired - Lifetime
- 1993-07-26 WO PCT/FR1993/000762 patent/WO1994002829A1/fr not_active Ceased
- 1993-07-26 DE DE69321454T patent/DE69321454T2/de not_active Expired - Fee Related
- 1993-07-26 JP JP6504225A patent/JPH07503323A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2120002A1 (en) | 1994-02-03 |
| ATE172028T1 (de) | 1998-10-15 |
| EP0605701B1 (fr) | 1998-10-07 |
| CA2120002C (en) | 2007-12-11 |
| JPH07503323A (ja) | 1995-04-06 |
| US5567593A (en) | 1996-10-22 |
| BR9305588A (pt) | 1995-05-30 |
| FR2694193B1 (fr) | 1994-10-28 |
| DE69321454T2 (de) | 1999-06-17 |
| WO1994002829A1 (fr) | 1994-02-03 |
| FR2694193A1 (fr) | 1994-02-04 |
| DE69321454D1 (de) | 1998-11-12 |
| EP0605701A1 (fr) | 1994-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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