ES2122010T3 - Muteinas de amilina. - Google Patents
Muteinas de amilina.Info
- Publication number
- ES2122010T3 ES2122010T3 ES93911125T ES93911125T ES2122010T3 ES 2122010 T3 ES2122010 T3 ES 2122010T3 ES 93911125 T ES93911125 T ES 93911125T ES 93911125 T ES93911125 T ES 93911125T ES 2122010 T3 ES2122010 T3 ES 2122010T3
- Authority
- ES
- Spain
- Prior art keywords
- insulin action
- muteins
- muscle
- suppressing
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/62—Insulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- Analytical Chemistry (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA INVENCION SE REFIERE A MUTEINAS DE LA ANILINA Y A DERIVADOS DE LAS MISMAS QUE TIENEN ACTIVIDAD DE SUPRESION DE LA ACCION DE LA INSULINA ASI COMO A LAS SALES FARMACOLOGICAMENTE ACEPTABLES DE LAS MISMAS. LAS MUTEINAS Y DERIVADOS DE LA INVENCION SON UTILES PARA SUPRIMIR LA ACCION DE LA INSULINA EN EL MUSCULO O EN LAS CELULAS MUSCULARES O PARA SUPRIMIR LA ACCION DE LA INSULINA EN UN MAMIFERO QUE LO NECESITE. DE ESTA FORMA, LA INVENCION SE REFIERE ADEMAS A UN METODO PARA SUPRIMIR LA ACCION DE LA INSULINA EN UN MAMIFERO QUE LO NECESITE Y A METODOS PARA SUPRIMIR LA ACCION DE LA INSULINA EN UN MUSCULO O EN CELULAS MUSCULARES ASI COMO A PREPARACIONES FARMACEUTICAS QUE COMPRENDEN LAS MUTEINAS ANTES DESCRITAS, LOS DERIVADOS O LAS SALES. LA INVENCION TAMBIEN SE REFIERE A UN METODO PARA COMPROBAR LA CAPACIDAD DE UN COMPUESTO PARA INHIBIR LA SUPRESION DE LA ACCION DE LA INSULINA EN UN MUSCULO O EN LAS CELULAS MUSCULARES PROVOCADA POR LA AMILINA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92678392A | 1992-08-06 | 1992-08-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2122010T3 true ES2122010T3 (es) | 1998-12-16 |
Family
ID=25453715
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93911125T Expired - Lifetime ES2122010T3 (es) | 1992-08-06 | 1993-05-12 | Muteinas de amilina. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0654042B1 (es) |
| JP (1) | JPH07506114A (es) |
| AT (1) | ATE171951T1 (es) |
| CA (1) | CA2141203C (es) |
| DE (1) | DE69321473T2 (es) |
| DK (1) | DK0654042T3 (es) |
| ES (1) | ES2122010T3 (es) |
| FI (1) | FI933476A (es) |
| WO (1) | WO1994003491A1 (es) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8720115D0 (en) * | 1987-08-26 | 1987-09-30 | Cooper G J S | Treatment of diabetes mellitus |
| WO1989006135A1 (en) * | 1988-01-11 | 1989-07-13 | Amylin Corporation | Treatment of type 2 diabetes mellitus |
-
1993
- 1993-05-12 WO PCT/US1993/004314 patent/WO1994003491A1/en active IP Right Grant
- 1993-05-12 CA CA002141203A patent/CA2141203C/en not_active Expired - Fee Related
- 1993-05-12 DK DK93911125T patent/DK0654042T3/da active
- 1993-05-12 AT AT93911125T patent/ATE171951T1/de not_active IP Right Cessation
- 1993-05-12 ES ES93911125T patent/ES2122010T3/es not_active Expired - Lifetime
- 1993-05-12 EP EP93911125A patent/EP0654042B1/en not_active Expired - Lifetime
- 1993-05-12 JP JP6505266A patent/JPH07506114A/ja active Pending
- 1993-05-12 DE DE69321473T patent/DE69321473T2/de not_active Expired - Fee Related
- 1993-08-05 FI FI933476A patent/FI933476A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE171951T1 (de) | 1998-10-15 |
| DE69321473D1 (en) | 1998-11-12 |
| WO1994003491A1 (en) | 1994-02-17 |
| EP0654042A1 (en) | 1995-05-24 |
| EP0654042B1 (en) | 1998-10-07 |
| FI933476A (fi) | 1994-02-07 |
| JPH07506114A (ja) | 1995-07-06 |
| CA2141203C (en) | 2003-07-08 |
| DE69321473T2 (de) | 1999-03-04 |
| DK0654042T3 (da) | 1999-02-15 |
| CA2141203A1 (en) | 1994-02-17 |
| FI933476A0 (fi) | 1993-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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