ES2119268T3 - Procedimiento para fabricar ranitidina base de calidad farmaceutica. - Google Patents
Procedimiento para fabricar ranitidina base de calidad farmaceutica.Info
- Publication number
- ES2119268T3 ES2119268T3 ES95107137T ES95107137T ES2119268T3 ES 2119268 T3 ES2119268 T3 ES 2119268T3 ES 95107137 T ES95107137 T ES 95107137T ES 95107137 T ES95107137 T ES 95107137T ES 2119268 T3 ES2119268 T3 ES 2119268T3
- Authority
- ES
- Spain
- Prior art keywords
- ranitidine
- manufacture
- procedure
- quality base
- pharmaceutical quality
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN PROCESO PARA LA FABRICACION DE UNA BASE (N-[2-[[[5-(DIMETILAMINO)METIL]-2-FURANIL]METIL]TIO]ETIL-N''-METIL-2-NITRO-1,1ETENEDIAMINA) DE RANITIDINA DE GRADO FARMACEUTICO. ESTUDIOS FARMACOLOGICOS IN VITRO E IN VIVO Y ESTUDIOS DE TOXICIDAD AGUDA INDICAN QUE ESTA COMPOSICION ES TAN ACTIVA Y SEGURA COMO EL HIDROCLORURO DE RANITIDINA FORMA F2.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/265,308 US5696275A (en) | 1994-05-13 | 1994-06-24 | Process for the manufacture of pharmaceutical grade ranitidine base |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2119268T3 true ES2119268T3 (es) | 1998-10-01 |
Family
ID=23009923
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95107137T Expired - Lifetime ES2119268T3 (es) | 1994-06-24 | 1995-05-11 | Procedimiento para fabricar ranitidina base de calidad farmaceutica. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0697411B1 (es) |
DE (1) | DE69503196T2 (es) |
ES (1) | ES2119268T3 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4055699A (en) * | 1998-06-17 | 2000-01-05 | Russinsky Limited | Ranitidine adduct |
YU52598A (sh) * | 1998-11-19 | 2001-05-28 | D.D. Zdravlje- sektor za istraživanje i razvoj | POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA |
CN108017601B (zh) * | 2017-12-28 | 2021-07-13 | 云鹏医药集团有限公司 | 一种精制雷尼替丁碱的方法 |
CN108727312B (zh) * | 2018-08-03 | 2021-05-18 | 上海金城素智药业有限公司 | 雷尼替丁口服制剂治疗糜烂性食管炎的新适应症 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1565966A (en) * | 1976-08-04 | 1980-04-23 | Allen & Hanburys Ltd | Aminoalkyl furan derivatives |
EP0285681B1 (de) * | 1987-04-06 | 1993-03-10 | HEUMANN PHARMA GMBH & CO | Verfahren zur Herstellung von Nitroethenderivaten |
-
1995
- 1995-05-11 DE DE1995603196 patent/DE69503196T2/de not_active Expired - Fee Related
- 1995-05-11 ES ES95107137T patent/ES2119268T3/es not_active Expired - Lifetime
- 1995-05-11 EP EP95107137A patent/EP0697411B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0697411B1 (en) | 1998-07-01 |
DE69503196D1 (de) | 1998-08-06 |
EP0697411A1 (en) | 1996-02-21 |
DE69503196T2 (de) | 1999-02-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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