ES2112311T3 - Vacuna acelular. - Google Patents
Vacuna acelular.Info
- Publication number
- ES2112311T3 ES2112311T3 ES92901932T ES92901932T ES2112311T3 ES 2112311 T3 ES2112311 T3 ES 2112311T3 ES 92901932 T ES92901932 T ES 92901932T ES 92901932 T ES92901932 T ES 92901932T ES 2112311 T3 ES2112311 T3 ES 2112311T3
- Authority
- ES
- Spain
- Prior art keywords
- amino acid
- parapertussis
- antigen
- protein
- expression vectors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229940030156 cell vaccine Drugs 0.000 title 1
- 241000588780 Bordetella parapertussis Species 0.000 abstract 3
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 239000013604 expression vector Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 239000002699 waste material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE DESCRIBE UNA PROTEINA QUE NO ESTA CONTAMINADA POR COMPONENTES DE B. PARAPERTUSSIS, QUE ES CAPAZ DE ENLAZAR CON UN ANTICUERPO QUE TAMBIEN ENLAZA CON EL ANTIGEN P70 NATIVO DE B. PARAPERTUSSIS, Y QUE TIENE (A) LA SECUENCIA AMINOACIDA MOSTRADA EN LA FIGURA 1, DE UN RESIDUO AMINOACIDO ASP 35 A ASN 643 O (B) UNA SECUENCIA AMINOACIDA QUE TIENE UNA HOMOLOGIA MAYOR DEL 98 % CON DICHA SECUENCIA AMINOACIDA (A). SE DESCRIBEN: EL DNA CODIFICADO DE LA PROTEINA, VECTORES DE EXPRESION QUE CONTIENEN DICHO DNA, CELULAS HUESPED TRANSFORMADAS POR TALES VECTORES DE EXPRESION Y EL EMPLEO DEL ANTIGEN EN UNA VACUNA PARA LA PREVENCION DE LAS INFECCIONES DE B. PARAPERTUSSIS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909027901A GB9027901D0 (en) | 1990-12-21 | 1990-12-21 | Acellular vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2112311T3 true ES2112311T3 (es) | 1998-04-01 |
Family
ID=10687500
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92901932T Expired - Lifetime ES2112311T3 (es) | 1990-12-21 | 1991-12-23 | Vacuna acelular. |
Country Status (6)
Country | Link |
---|---|
EP (2) | EP0573435B1 (es) |
AT (1) | ATE159758T1 (es) |
DE (1) | DE69128095T2 (es) |
ES (1) | ES2112311T3 (es) |
GB (1) | GB9027901D0 (es) |
WO (1) | WO1992011292A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2303833T3 (es) * | 2000-05-25 | 2008-09-01 | Institut Pasteur | Polipeptidos que contienen polimorfismos de las regiones repetidas de pertactina en bordetella pertussis, bordetella parapertussis y bordetella bronchiseptica, su uso en diagnostico y en composiciones inmunogenicas. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE121754T1 (de) * | 1989-09-04 | 1995-05-15 | Wellcome Found | Vakzine gegen bordetella. |
GB9007416D0 (en) * | 1990-04-02 | 1990-05-30 | Wellcome Found | Expression of heterologous protein in yeast |
-
1990
- 1990-12-21 GB GB909027901A patent/GB9027901D0/en active Pending
-
1991
- 1991-12-23 AT AT92901932T patent/ATE159758T1/de not_active IP Right Cessation
- 1991-12-23 EP EP92901932A patent/EP0573435B1/en not_active Revoked
- 1991-12-23 DE DE69128095T patent/DE69128095T2/de not_active Revoked
- 1991-12-23 WO PCT/GB1991/002302 patent/WO1992011292A1/en not_active Application Discontinuation
- 1991-12-23 EP EP97104861A patent/EP0789031A2/en not_active Withdrawn
- 1991-12-23 ES ES92901932T patent/ES2112311T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1992011292A1 (en) | 1992-07-09 |
ATE159758T1 (de) | 1997-11-15 |
EP0573435B1 (en) | 1997-10-29 |
EP0789031A2 (en) | 1997-08-13 |
DE69128095T2 (de) | 1998-02-26 |
EP0573435A1 (en) | 1993-12-15 |
GB9027901D0 (en) | 1991-02-13 |
DE69128095D1 (de) | 1997-12-04 |
EP0789031A3 (es) | 1997-08-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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