ES2108099T3 - Agentes sistemicos de hormonas juveniles contra los ectoparasitos. - Google Patents

Agentes sistemicos de hormonas juveniles contra los ectoparasitos.

Info

Publication number
ES2108099T3
ES2108099T3 ES92403478T ES92403478T ES2108099T3 ES 2108099 T3 ES2108099 T3 ES 2108099T3 ES 92403478 T ES92403478 T ES 92403478T ES 92403478 T ES92403478 T ES 92403478T ES 2108099 T3 ES2108099 T3 ES 2108099T3
Authority
ES
Spain
Prior art keywords
group
different
integer
hydrogen
halogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92403478T
Other languages
English (en)
Inventor
Thomas A Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virbac Corp
Original Assignee
Virbac Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virbac Corp filed Critical Virbac Corp
Application granted granted Critical
Publication of ES2108099T3 publication Critical patent/ES2108099T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA INVENCION SE REFIERE A UN METODO PARA LUCHAR CONTRA LOS ECTOPARASITOS. MAS PARTICULARMENTE, SE REFIERE A UN METODO DE TRATAMIENTO EN EL QUE EL ANIMAL DE SANGRE CALIENTE RECIBE UNA DOSIS DE UNA CANTIDAD EFICAZ DESDE EL PUNTO DE VISTA OVICIDA DE UN COMPUESTO HETEROCICLICO QUE CONTIENE NITROGENO ELEGIDO EN EL GRUPO REPRESENTADO POR LA FORMULA: EN LA QUE R1 ES UNO DE LOS SIGUIENTES GRUPOS: EN LOS QUE R7,R8,R9,R10,R11,R12,R13,R14,R15,R16 Y R17 IDENTICOS O DIFERENTES SON CADA UNO UN ATOMO DE HIDROGENO O DE HALOGENO, UN GRUPO ALCOXY EN C1-4, ALQUILTIO EN C1-4, TRIFLUOROMETILO O NITRO; R18, R19, R20, IDENTICOS O DIFERENTES, SON CADA UNO UN ATOMO DE HIDROGENO O UN GRUPO METILO, K ES UN NUMERO ENTERO DE 0 A 1, Y / L ES UN NUMERO ENTERO DE 0 A 3; R2 Y R3 IDENTICOS O DIFERENTES SON CADA UNO UN ATOMO DE HIDROGENO O DE HALOGENO O UN GRUPO METILO: R4 ES UN ATOMO DE HALOGENO O UN GRUPO METILO; R5 Y R6, IDENTICOS O DIFERENTES SON CADA UNO UN ATOMO DE HIDROGENO O DE HALOGENO, UN GRUPO HALOALQUILO EN C1-4,O HALOALCOXI EN C14; X, Y Y Z, IDENTICOS O DIFERENTES SON CADA UNO UN ATOMO DE OXIGENO,DE AZUFRE O UN GRUPO METILENO, M ES UN NUMERO ENTERO DE 0 A 4, Y N ES UN NUMERO ENTERO DE 0 A 2, QUE ES TRANSMITIDO AL ECTOPARASITO POR LA SANGRE DEL ANIMAL. SEGUN OTRO ASPECTO, SE UTILIZA TAMBIEN UN COMPUESTO ELEGIDO EN EL GRUPO QUE CONSISTE EN IVERMECTINA, MILBEMICINA, MILBEMICINA OXIMA, MOXIDECTINA Y AVERMECTINA Y DERIVADOS DE AVERMECTINA.
ES92403478T 1991-12-23 1992-12-21 Agentes sistemicos de hormonas juveniles contra los ectoparasitos. Expired - Lifetime ES2108099T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81243091A 1991-12-23 1991-12-23

Publications (1)

Publication Number Publication Date
ES2108099T3 true ES2108099T3 (es) 1997-12-16

Family

ID=25209544

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92403478T Expired - Lifetime ES2108099T3 (es) 1991-12-23 1992-12-21 Agentes sistemicos de hormonas juveniles contra los ectoparasitos.

Country Status (8)

Country Link
EP (1) EP0549441B1 (es)
JP (1) JP3170077B2 (es)
AT (1) ATE156357T1 (es)
AU (1) AU660205B2 (es)
DE (1) DE69221454T2 (es)
ES (1) ES2108099T3 (es)
NZ (1) NZ245548A (es)
ZA (1) ZA929950B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5632999A (en) * 1993-08-18 1997-05-27 Virbac, Inc. Sustained release pyriproxifen compositions for parasite control
TW328044B (en) * 1994-12-01 1998-03-11 Mitsui Toatsu Chemicals An insecticidal and acaricidal composition
IE80657B1 (en) * 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
AU5837900A (en) * 1999-07-23 2001-02-13 Bioparken As Control of crustacean infestation of aquatic animals
AU5838000A (en) * 1999-07-23 2001-02-13 Bioparken As Novel juvenile hormone analogues and their use as antifouling agents
JP4288794B2 (ja) * 1999-10-26 2009-07-01 住友化学株式会社 殺虫・殺ダニ組成物
JP4701538B2 (ja) * 2001-05-21 2011-06-15 住友化学株式会社 農業害虫防除剤組成物
PT2598151T (pt) * 2010-07-30 2019-04-15 Ceva Sante Animale Sa Composições para o tratamento da infestação por vermes do coração
JP6033610B2 (ja) * 2012-08-31 2016-11-30 日本ケーブル株式会社 避難支援装置
UY37780A (es) * 2017-06-26 2019-01-31 Merial Inc Composiciones de gránulos parasiticidas con doble principio activo, sus métodos y usos

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US4031239A (en) 1975-02-13 1977-06-21 American Cyanamid Company Cyclopropanecarboxylates for systemic control of ectoparasites
US3962458A (en) 1975-02-13 1976-06-08 American Cyanamid Company Systemic control of ectoparasites with pyrethroids
US4006236A (en) 1975-08-04 1977-02-01 American Cyanamid Company Substituted octahydrophenanthridine pesticides
US4053631A (en) 1976-04-02 1977-10-11 American Cyanamid Company Systemic control of ectoparasites with α-cyano-m-phenoxybenzyl α1 -C4 alkyl-2-naphthaleneacetates
US4092421A (en) 1977-05-13 1978-05-30 The Dow Chemical Company Method of controlling manure-breeding insects
US4089975A (en) 1977-05-13 1978-05-16 The Dow Chemical Company Method of controlling manure-breeding insects
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4166107A (en) 1978-07-25 1979-08-28 The United States Of America As Represented By The Secretary Of Agriculture Sustained release bolus formulations containing insect growth regulators for control of livestock pests
JPS5632481A (en) 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
FR2470104A1 (fr) 1979-11-19 1981-05-29 Carbonisation Entr Ceram Composition pulverulente et piece refractaire obtenue a partir de cette composition
US4251223A (en) 1979-12-17 1981-02-17 Miles Laboratories, Inc. Sensitizers for peroxidative activity tests
US4323582A (en) 1980-07-21 1982-04-06 Siegel Norman H Method of treating animals and humans for internal and external parasites
JPS59108785A (ja) 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体
JPS59199673A (ja) 1983-04-25 1984-11-12 Sumitomo Chem Co Ltd 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤
US4694974A (en) 1985-06-14 1987-09-22 Michael Heck Escapement apparatus for an automatic screw feeding machine
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
NZ221262A (en) 1986-08-06 1990-08-28 Ciba Geigy Ag Preventing the reinfestation of dogs and cats by fleas by administering to the host a flea growth inhibiting substance orally, parenterally or by implant
US4751223A (en) 1986-10-14 1988-06-14 Hoechst-Roussel Pharmaceuticals, Inc. Antiinflammatory and analgesic aminoalkyl tetracyclic benzodiazepines
DE3805235A1 (de) 1988-02-19 1989-08-31 Shell Int Research Verfahren zur herstellung von 3,3-diarylacrylsaeureamiden
US4988824A (en) 1989-09-11 1991-01-29 Maulding Donald R Process for the preparation of 23-(C1-C6 alkyloxime)-LL-F28249 compounds

Also Published As

Publication number Publication date
DE69221454T2 (de) 1997-12-11
EP0549441A1 (fr) 1993-06-30
AU3014592A (en) 1993-06-24
JPH06211792A (ja) 1994-08-02
ZA929950B (en) 1993-11-03
AU660205B2 (en) 1995-06-15
JP3170077B2 (ja) 2001-05-28
EP0549441B1 (fr) 1997-08-06
DE69221454D1 (de) 1997-09-11
ATE156357T1 (de) 1997-08-15
NZ245548A (en) 1996-04-26

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