ES2105597T3 - Procedimiento para la preparacion de alfa-aril-gamma-butirolactonas. - Google Patents

Procedimiento para la preparacion de alfa-aril-gamma-butirolactonas.

Info

Publication number
ES2105597T3
ES2105597T3 ES94900256T ES94900256T ES2105597T3 ES 2105597 T3 ES2105597 T3 ES 2105597T3 ES 94900256 T ES94900256 T ES 94900256T ES 94900256 T ES94900256 T ES 94900256T ES 2105597 T3 ES2105597 T3 ES 2105597T3
Authority
ES
Spain
Prior art keywords
formula
preparation
butirolactonas
aril
alfa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94900256T
Other languages
English (en)
Inventor
Robin Gerald Shepherd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Application granted granted Critical
Publication of ES2105597T3 publication Critical patent/ES2105597T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D315/00Heterocyclic compounds containing rings having one oxygen atom as the only ring hetero atom according to more than one of groups C07D303/00 - C07D313/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

UN PROCESO PARA LA PREPARACION DE UNA LACTONA DE FORMULA GENERAL (I), DONDE R ES UN GRUPO FENILO OPCIONALMENTE SUSTITUIDO O UN RADICAL HETEROARILO MONO- O BICICLICO OPCIONALMENTE SUSTITUIDO CUYO PROCESO COMPRENDE LA REACCION DE UN ANION DE UN MALONATO DE FORMULA (II) CON UN COMPUESTO DE ETILENO DE FORMULA (III) Y-CH2-CH2OZ, PARA PROPORCIONAR UN COMPUESTO DE FORMULA (IV) Y LA HIDROLIZACION DEL COMPUESTO DE FORMULA (IV) PARA PROPORCIONAR UNA LACTONA DE FORMULA (I). LAS LACTONAS SON DE USO COMO COMPUESTOS PARA LA PREPARACION DE AGLUTINANTES 5-HT1A.
ES94900256T 1992-12-03 1993-11-25 Procedimiento para la preparacion de alfa-aril-gamma-butirolactonas. Expired - Lifetime ES2105597T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929225257A GB9225257D0 (en) 1992-12-03 1992-12-03 Lactone

Publications (1)

Publication Number Publication Date
ES2105597T3 true ES2105597T3 (es) 1997-10-16

Family

ID=10726039

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94900256T Expired - Lifetime ES2105597T3 (es) 1992-12-03 1993-11-25 Procedimiento para la preparacion de alfa-aril-gamma-butirolactonas.

Country Status (16)

Country Link
US (1) US5629432A (es)
EP (1) EP0672039B1 (es)
JP (1) JP3274866B2 (es)
KR (1) KR100301335B1 (es)
AT (1) ATE155134T1 (es)
AU (1) AU5532494A (es)
CA (1) CA2150948A1 (es)
DE (1) DE69312085T2 (es)
DK (1) DK0672039T3 (es)
ES (1) ES2105597T3 (es)
GB (1) GB9225257D0 (es)
GR (1) GR3024083T3 (es)
MX (1) MX9307561A (es)
PH (1) PH31300A (es)
WO (1) WO1994012487A1 (es)
ZA (1) ZA938873B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7956201B2 (en) * 2006-11-06 2011-06-07 Hoffman-La Roche Inc. Process for the preparation of (S)-4-fluoromethyl-dihydro-furan-2-one
DE112012006785T5 (de) * 2012-08-09 2015-07-16 Empire Technology Development Llc Flammhemmendes Nylon
KR102178533B1 (ko) 2020-05-08 2020-11-17 박관철 정위치 주차장치
CN114213367B (zh) * 2022-01-17 2023-05-12 西北工业大学 一种使用3,4-环氧-1-丁醇合成γ-丁内酯的方法

Also Published As

Publication number Publication date
ZA938873B (en) 1995-05-26
GB9225257D0 (en) 1993-01-27
DE69312085T2 (de) 1998-02-19
KR100301335B1 (ko) 2001-11-22
PH31300A (en) 1998-07-06
ATE155134T1 (de) 1997-07-15
WO1994012487A1 (en) 1994-06-09
JP3274866B2 (ja) 2002-04-15
MX9307561A (es) 1995-01-31
EP0672039B1 (en) 1997-07-09
DE69312085D1 (de) 1997-08-14
AU5532494A (en) 1994-06-22
US5629432A (en) 1997-05-13
EP0672039A1 (en) 1995-09-20
DK0672039T3 (da) 1997-08-18
GR3024083T3 (en) 1997-10-31
JPH08503939A (ja) 1996-04-30
CA2150948A1 (en) 1994-06-09
KR950704289A (ko) 1995-11-17

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