ES2104794T3 - 3-isoxazolilfenil-compuestos, su obtencion y su empleo. - Google Patents
3-isoxazolilfenil-compuestos, su obtencion y su empleo.Info
- Publication number
- ES2104794T3 ES2104794T3 ES92119064T ES92119064T ES2104794T3 ES 2104794 T3 ES2104794 T3 ES 2104794T3 ES 92119064 T ES92119064 T ES 92119064T ES 92119064 T ES92119064 T ES 92119064T ES 2104794 T3 ES2104794 T3 ES 2104794T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- hydrogen
- given
- case
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical class [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- -1 PHENYLETHENYL Chemical class 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4137940A DE4137940A1 (de) | 1991-11-18 | 1991-11-18 | 3-isoxazolylphenylverbindungen, ihre herstellung und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2104794T3 true ES2104794T3 (es) | 1997-10-16 |
Family
ID=6445077
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES92119064T Expired - Lifetime ES2104794T3 (es) | 1991-11-18 | 1992-11-06 | 3-isoxazolilfenil-compuestos, su obtencion y su empleo. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5256666A (OSRAM) |
| EP (1) | EP0543238B1 (OSRAM) |
| JP (1) | JP3246964B2 (OSRAM) |
| KR (1) | KR100234925B1 (OSRAM) |
| CA (1) | CA2082574C (OSRAM) |
| DE (2) | DE4137940A1 (OSRAM) |
| ES (1) | ES2104794T3 (OSRAM) |
| TW (1) | TW223064B (OSRAM) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8127298A (en) * | 1997-07-09 | 1999-02-08 | Nippon Soda Co., Ltd. | Isoxazole compounds, process for the preparation thereof, and insecticides and acaricides |
| MY151199A (en) * | 2001-11-02 | 2014-04-30 | Rigel Pharmaceuticals Inc | Substituted diphenyl heterocycles useful for treating hcv infection |
| HUP0402535A2 (hu) | 2001-12-10 | 2005-04-28 | Bristol-Myers Squibb Co. | RSV fúzió inhibitor hatású imidazo-piridin-vegyület dihidroklorid-monohidrát sója és az ezt tartalmazó gyógyszerkészítmények |
| HRP20050168A2 (en) * | 2002-08-23 | 2005-10-31 | Rigel Pharmaceuticals | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
| US7326790B2 (en) * | 2003-05-02 | 2008-02-05 | Rigel Pharmaceuticals, Inc. | Diphenylisoxazole compounds and hydro isomers thereof |
| WO2004099164A1 (en) | 2003-05-02 | 2004-11-18 | Rigel Pharmaceuticals, Inc. | Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating hcv infection |
| US7220745B2 (en) | 2003-05-15 | 2007-05-22 | Rigel Pharmaceuticals | Heterocyclic compounds useful to treat HCV |
| WO2005049065A2 (en) * | 2003-11-19 | 2005-06-02 | Rigel Pharmaceuticals, Inc. | Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections |
| US7514434B2 (en) | 2004-02-23 | 2009-04-07 | Rigel Pharmaceuticals, Inc. | Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof |
| JP2007530582A (ja) * | 2004-03-26 | 2007-11-01 | ライジェル ファーマシューティカルズ， インコーポレイテッド | 代謝可能部分を含む複素環抗ウイルス化合物およびその使用 |
| JP2008540425A (ja) * | 2005-05-02 | 2008-11-20 | ライジェル ファーマシューティカルズ， インコーポレイテッド | 代謝可能部分を含む複素環式抗ウイルス性化合物およびその使用 |
| NL2000351C2 (nl) | 2005-12-22 | 2007-09-11 | Pfizer Prod Inc | Estrogeen-modulatoren. |
| EP2545964A1 (en) | 2011-07-13 | 2013-01-16 | Phenex Pharmaceuticals AG | Novel FXR (NR1H4) binding and activity modulating compounds |
| CA2968836C (en) | 2016-06-13 | 2025-09-02 | Gilead Sciences, Inc. | FXR MODULATING COMPOUNDS (NR1H4) |
| JP6678779B2 (ja) | 2016-06-13 | 2020-04-08 | ギリアード サイエンシーズ， インコーポレイテッド | Ｆｘｒ（ｎｒ１ｈ４）調節化合物 |
| EP4122464B1 (en) | 2017-03-28 | 2024-05-15 | Gilead Sciences, Inc. | Therapeutic combinations for treating liver diseases |
| EP3911647B1 (en) | 2019-01-15 | 2023-12-13 | Gilead Sciences, Inc. | Isoxazole compound as fxr agonist and pharmaceutical compositions comprising same |
| AU2020225225B2 (en) | 2019-02-19 | 2022-12-22 | Gilead Sciences, Inc. | Solid forms of FXR agonists |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3140632A1 (de) * | 1981-10-13 | 1983-04-21 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von (alpha)-dicyano-trimethylsilyloxy-verbindungen (i) |
| DE3604781A1 (de) * | 1986-02-13 | 1987-08-27 | Schering Ag | Neue silane, verfahren zu ihrer herstellung und diese verbindungen enthaltende einsektizide mittel |
| CN1025470C (zh) * | 1986-05-31 | 1994-07-20 | 赫彻斯特股份公司 | 含新型硅烷衍生物的农药，杀虫剂和杀螨剂组合物 |
| US5185025A (en) * | 1988-11-21 | 1993-02-09 | Monsanto Company | Substituted pyrazoles and their use as herbicides |
-
1991
- 1991-11-18 DE DE4137940A patent/DE4137940A1/de not_active Withdrawn
-
1992
- 1992-11-06 ES ES92119064T patent/ES2104794T3/es not_active Expired - Lifetime
- 1992-11-06 DE DE59208576T patent/DE59208576D1/de not_active Expired - Lifetime
- 1992-11-06 EP EP92119064A patent/EP0543238B1/de not_active Expired - Lifetime
- 1992-11-10 TW TW081108969A patent/TW223064B/zh active
- 1992-11-10 CA CA002082574A patent/CA2082574C/en not_active Expired - Fee Related
- 1992-11-13 US US07/975,733 patent/US5256666A/en not_active Expired - Lifetime
- 1992-11-17 JP JP30686692A patent/JP3246964B2/ja not_active Expired - Fee Related
- 1992-11-17 KR KR1019920021571A patent/KR100234925B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TW223064B (OSRAM) | 1994-05-01 |
| KR100234925B1 (ko) | 1999-12-15 |
| CA2082574A1 (en) | 1993-05-19 |
| US5256666A (en) | 1993-10-26 |
| EP0543238A1 (de) | 1993-05-26 |
| DE4137940A1 (de) | 1993-05-19 |
| DE59208576D1 (de) | 1997-07-10 |
| CA2082574C (en) | 2003-05-13 |
| JP3246964B2 (ja) | 2002-01-15 |
| JPH05247064A (ja) | 1993-09-24 |
| KR930010050A (ko) | 1993-06-21 |
| EP0543238B1 (de) | 1997-06-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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