ES2099740T3 - Aplicacion terapeutica de agonistas del receptor h3 de la histamina, nuevos compuestos y utilizacion para la preparacion de medicamentos. - Google Patents

Aplicacion terapeutica de agonistas del receptor h3 de la histamina, nuevos compuestos y utilizacion para la preparacion de medicamentos.

Info

Publication number
ES2099740T3
ES2099740T3 ES91400889T ES91400889T ES2099740T3 ES 2099740 T3 ES2099740 T3 ES 2099740T3 ES 91400889 T ES91400889 T ES 91400889T ES 91400889 T ES91400889 T ES 91400889T ES 2099740 T3 ES2099740 T3 ES 2099740T3
Authority
ES
Spain
Prior art keywords
histamine
preparation
therapeutic application
medicines
receptor agonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91400889T
Other languages
English (en)
Inventor
Jean Charles Schwartz
Monique Garbarg
Jean Michel Arrang
Charon Robin Ganellin
Jeanne Marie Lecomte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioprojet SC
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Bioprojet SC
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioprojet SC, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Bioprojet SC
Application granted granted Critical
Publication of ES2099740T3 publication Critical patent/ES2099740T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

APLICACION TERAPEUTICA DE DERIVADOS DE HISTAMINA, NUEVOS DERIVADOS DE HISTAMINA Y UTILIZACION DE ESTOS DERIVADOS PARA LA PREPARACION DE MEDICAMENTOS. LA INVENCION REIVINDICA COMO MEDICAMENTOS DE ACCION AGONISTA DEL RECEPTOR H SUB 3 DE HISTAMINA, LA S-[2-4(5)-IMIDAZOLIL)-ETIL]ISOTIOUREA ASI COMO DEL NUEVO COMPUESTO DE FORMULA SIENDO UTILES ESTOS COMPUESTOS PARA LA PREPARACION DE MEDICAMENTOS DESTINADOS A SER UTILIZADOS COMO AGENTE HIPNOTICO, PROMOTOR DEL SUEÑO, TRANQUILIZANTE, SEDANTE, ANXIOLITICO, ANTIASMATICO, ANTIINFLAMATORIO, EN PARTICULAR BRONQUITICO, CUTANEO U OCULAR O ANTIULCEROSO GASTRICO.
ES91400889T 1990-04-13 1991-04-02 Aplicacion terapeutica de agonistas del receptor h3 de la histamina, nuevos compuestos y utilizacion para la preparacion de medicamentos. Expired - Lifetime ES2099740T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9004861A FR2660862B1 (fr) 1990-04-13 1990-04-13 Application therapeutique de derives de l'histamine, nouveau derive de l'histamine et utilisation de ces derives pour la preparation de medicaments.

Publications (1)

Publication Number Publication Date
ES2099740T3 true ES2099740T3 (es) 1997-06-01

Family

ID=9395796

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91400889T Expired - Lifetime ES2099740T3 (es) 1990-04-13 1991-04-02 Aplicacion terapeutica de agonistas del receptor h3 de la histamina, nuevos compuestos y utilizacion para la preparacion de medicamentos.

Country Status (8)

Country Link
EP (1) EP0458661B1 (es)
JP (1) JPH0532635A (es)
AT (1) ATE150305T1 (es)
DE (1) DE69125204T2 (es)
DK (1) DK0458661T3 (es)
ES (1) ES2099740T3 (es)
FR (1) FR2660862B1 (es)
GR (1) GR3023083T3 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321039A (en) * 1990-04-13 1994-06-14 Societe Civile Bioprojet Method of inducing a histamine agonist action on H2 receptors
GB9715816D0 (en) * 1997-07-25 1997-10-01 Black James Foundation Histamine H receptor ligands
US6407132B1 (en) 1997-07-25 2002-06-18 James Black Foundation Limited Substituted imidazole derivatives and their use as histamine H3 receptor ligands
EP1147092A1 (en) 1999-01-18 2001-10-24 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6908926B1 (en) 1999-04-16 2005-06-21 Novo Nordisk A/S Substituted imidazoles, their preparation and use
US6437147B1 (en) 2000-03-17 2002-08-20 Novo Nordisk Imidazole compounds
US6610721B2 (en) 2000-03-17 2003-08-26 Novo Nordisk A/S Imidazo heterocyclic compounds
EP3378477A1 (en) * 2017-03-21 2018-09-26 BIOPROJET Pharma New therapeutical use of h3-ligands

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758145A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Iso-thio-urees et derives
US3818097A (en) * 1969-10-29 1974-06-18 Smith Kline French Lab Method of inhibiting histamine activity with isothioureas
US3759944A (en) * 1970-10-14 1973-09-18 Smith Kline French Lab Isothioureas and their derivatives
US3954982A (en) * 1972-04-20 1976-05-04 Smith Kline & French Laboratories Limited Pharmaceutical compositions and method of inhibiting H-1 and H-2 histamine receptors
GB8916947D0 (en) * 1989-07-25 1989-09-13 Smith Kline French Lab Medicaments

Also Published As

Publication number Publication date
GR3023083T3 (en) 1997-07-30
FR2660862B1 (fr) 1994-09-23
DK0458661T3 (da) 1997-07-28
DE69125204D1 (de) 1997-04-24
ATE150305T1 (de) 1997-04-15
EP0458661A1 (fr) 1991-11-27
EP0458661B1 (fr) 1997-03-19
FR2660862A1 (fr) 1991-10-18
DE69125204T2 (de) 1997-06-26
JPH0532635A (ja) 1993-02-09

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