ES2099275T3 - Comprimido multiparticulas de desleimiento rapido. - Google Patents
Comprimido multiparticulas de desleimiento rapido.Info
- Publication number
- ES2099275T3 ES2099275T3 ES92917134T ES92917134T ES2099275T3 ES 2099275 T3 ES2099275 T3 ES 2099275T3 ES 92917134 T ES92917134 T ES 92917134T ES 92917134 T ES92917134 T ES 92917134T ES 2099275 T3 ES2099275 T3 ES 2099275T3
- Authority
- ES
- Spain
- Prior art keywords
- multiparticles
- compressed
- tablet
- quick dissolution
- imparting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004090 dissolution Methods 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000013081 microcrystal Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cephalosporin Compounds (AREA)
Abstract
COMPRIMIDO MULTIPARTICULAR DE DESINTEGRACION RAPIDA CUYA MEZCLA DE EXCIPIENTES PERMITE CONFERIR UNA VELOCIDAD DE DESINTEGRACION TAL QUE SU DESAGREGACION EN LA CAVIDAD BUCAL SE PRODUCE EN UN TIEMPO EXTREMADAMENTE CORTO Y PARTICULARMENTE INFERIOR A 60 SEGUNDOS, CARACTERIZADO POR EL HECHO DE QUE LA SUSTANCIA ACTIVA ESTA PRESENTE EN FORMA DE MICROCRISTALES REVESTIDOS O DE MICROGRANULOS REVESTIDOS O NO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR919109245A FR2679451B1 (fr) | 1991-07-22 | 1991-07-22 | Comprime multiparticulaire a delitement rapide. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2099275T3 true ES2099275T3 (es) | 1997-05-16 |
Family
ID=9415391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92917134T Expired - Lifetime ES2099275T3 (es) | 1991-07-22 | 1992-07-21 | Comprimido multiparticulas de desleimiento rapido. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0548356B1 (es) |
JP (1) | JP2820319B2 (es) |
KR (1) | KR100197465B1 (es) |
AT (1) | ATE148339T1 (es) |
CA (1) | CA2092074C (es) |
DE (1) | DE69217191T2 (es) |
DK (1) | DK0548356T3 (es) |
ES (1) | ES2099275T3 (es) |
FR (1) | FR2679451B1 (es) |
GR (1) | GR3023281T3 (es) |
HK (1) | HK1007414A1 (es) |
WO (1) | WO1993001805A1 (es) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4318577A1 (de) * | 1993-06-04 | 1994-12-08 | Merck Patent Gmbh | Schmiermittelfreie, arzneimittelhaltige Tabletten |
CA2128820A1 (en) * | 1993-07-27 | 1995-01-28 | Walter G. Gowan, Jr. | Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof |
DE4333190C2 (de) * | 1993-09-29 | 1996-05-30 | Korsatko Werner Univ Prof Dr E | Zerbeißtablette mit verzögerter Wirkstoff-Freisetzung |
US5807578A (en) * | 1995-11-22 | 1998-09-15 | Lab Pharmaceutical Research International Inc. | Fast-melt tablet and method of making same |
US5807577A (en) * | 1995-11-22 | 1998-09-15 | Lab Pharmaceutical Research International Inc. | Fast-melt tablet and method of making same |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
FR2766089B1 (fr) * | 1997-07-21 | 2000-06-02 | Prographarm Lab | Comprime multiparticulaire perfectionne a delitement rapide |
TW527195B (en) | 1997-10-09 | 2003-04-11 | Ssp Co Ltd | Fast-soluble solid pharmaceutical combinations |
FR2771291B1 (fr) * | 1997-11-21 | 2000-02-25 | Ethypharm Lab Prod Ethiques | Spheroides, procede de preparation et compositions pharmaceutiques |
AU741992B2 (en) * | 1998-03-06 | 2001-12-13 | Adare Pharmaceuticals S.R.L. | Fast disintegrating tablets |
CN1195500C (zh) | 1998-05-18 | 2005-04-06 | 武田药品工业株式会社 | 可口腔崩解的片剂 |
FR2781793B1 (fr) * | 1998-08-03 | 2001-07-20 | Prographarm Lab | Procede de fabrication de granules de gabapentine enrobes |
FR2785539B1 (fr) * | 1998-11-06 | 2004-04-09 | Prographarm Laboratoires | Particules enrobees d'ibuprofene cristallin granule |
FR2785538B1 (fr) | 1998-11-06 | 2004-04-09 | Prographarm Laboratoires | Comprime a delitement rapide perfectionne |
FR2790387B1 (fr) | 1999-03-01 | 2001-05-18 | Prographarm Laboratoires | Comprime orodispersible presentant une faible friabilite et son procede de preparation |
GB9908014D0 (en) | 1999-04-08 | 1999-06-02 | Scherer Corp R P | Pharmaceutical compositions |
FR2795962B1 (fr) * | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
DE19931708A1 (de) | 1999-07-08 | 2001-01-18 | Bayer Ag | Verfahren zur Herstellung schnell zerfallender, fester pharmazeutischer Zubereitungen |
ES2366430T3 (es) | 2001-06-20 | 2011-10-20 | Takeda Pharmaceutical Company Limited | Método para fabricar comprimidos. |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
FR2831820B1 (fr) * | 2001-11-05 | 2004-08-20 | Ethypharm Sa | Comprime orodispersible presentant une grande homogeneite et son procede de preparation |
GB0204771D0 (en) * | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Fast disintegrating tablets |
FR2837100B1 (fr) * | 2002-03-18 | 2004-07-23 | Flamel Tech Sa | Comprimes a bases de microcapsules a liberation modifiee |
WO2003084518A2 (fr) | 2002-04-09 | 2003-10-16 | Flamel Technologies | Suspension orale de microcapsules de principes actifs |
US20040005362A1 (en) * | 2002-07-03 | 2004-01-08 | Rajneesh Taneja | Liquid dosage forms of acid labile drugs |
DE10232020A1 (de) | 2002-07-04 | 2004-02-26 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Neurorezeptoraktive Heteroarencarboxamide |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
FR2861990B1 (fr) | 2003-11-10 | 2006-02-10 | Nouveaux Produits Pharma | Comprimes faiblement doses a reseau de polymeres |
DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
US8545881B2 (en) | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
US20060105039A1 (en) | 2004-10-21 | 2006-05-18 | Jin-Wang Lai | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
WO2006085497A1 (ja) * | 2005-02-09 | 2006-08-17 | Kissei Pharmaceutical Co., Ltd. | 口腔内崩壊錠 |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
WO2006133349A2 (en) * | 2005-06-08 | 2006-12-14 | Alpharma, Inc. | Orally disintegrable sleep aid formulations |
PT2046300E (pt) | 2006-08-04 | 2010-07-01 | Ethypharm Sa | Comprimido multicamadas de desintegraão oral |
NZ574544A (en) | 2006-08-04 | 2011-12-22 | Ethypharm Sa | Granule and orally disintegrating tablet comprising oxycodone |
JP5366558B2 (ja) | 2006-12-28 | 2013-12-11 | 武田薬品工業株式会社 | 口腔内崩壊性固形製剤 |
JP5228359B2 (ja) * | 2007-04-12 | 2013-07-03 | ニプロ株式会社 | 主薬粒子及びその製造方法ならびに口腔内崩壊錠 |
FR2920311B1 (fr) * | 2007-08-31 | 2010-06-18 | Galenix Innovations | Composition solide, orodispersible et/ou dispersible, sans excipient a effet notoire et son procede de preparation |
JP2010540588A (ja) | 2007-10-01 | 2010-12-24 | ラボラトリオス、レスビ、ソシエダッド、リミターダ | 口腔内崩壊錠剤 |
WO2009113703A2 (en) | 2008-03-11 | 2009-09-17 | Takeda Pharmaceutical Company Limited | Orally-disintegrating solid preparation |
FR2933299B1 (fr) | 2008-07-04 | 2012-02-03 | Roquette Freres | Mannitol orodispersible |
CA2782285A1 (en) | 2009-12-02 | 2011-06-09 | Luigi Mapelli | Fexofenadine microcapsules and compositions containing them |
FR2962550B1 (fr) | 2010-07-06 | 2013-06-14 | Ethypharm Sa | Methode pour lutter contre la soumission chimique, utilisation d'agent colorant pour lutter contre la soumission chimique et composition pharmaceutique permettant la mise en oeuvre de la methode |
FR2962331B1 (fr) | 2010-07-06 | 2020-04-24 | Ethypharm | Forme pharmaceutique pour lutter contre la soumission chimique, methode la mettant en oeuvre |
AU2011350396A1 (en) | 2010-12-27 | 2013-07-11 | Takeda Pharmaceutical Company Limited | Orally disintegrating tablet |
FR2999432B1 (fr) | 2012-12-17 | 2014-12-12 | Ethypharm Sa | Comprimes orodispersibles obtenus par compression moulage |
US10881610B2 (en) | 2016-06-16 | 2021-01-05 | Towa Pharmaceutical Co., Ltd. | Orally disintegrating tablet |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1200178B (it) * | 1986-07-23 | 1989-01-05 | Alfa Farmaceutici Spa | Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica |
DE3887179T2 (de) * | 1987-03-02 | 1994-06-16 | Brocades Pharma Bv | Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung. |
CA2019324C (en) * | 1989-07-10 | 1996-08-20 | Robert L. Jerzewski | Fosinopril tablet formulations |
-
1991
- 1991-07-22 FR FR919109245A patent/FR2679451B1/fr not_active Expired - Lifetime
-
1992
- 1992-07-21 ES ES92917134T patent/ES2099275T3/es not_active Expired - Lifetime
- 1992-07-21 DK DK92917134.6T patent/DK0548356T3/da active
- 1992-07-21 DE DE69217191T patent/DE69217191T2/de not_active Expired - Lifetime
- 1992-07-21 JP JP5502647A patent/JP2820319B2/ja not_active Expired - Lifetime
- 1992-07-21 EP EP92917134A patent/EP0548356B1/fr not_active Revoked
- 1992-07-21 WO PCT/FR1992/000715 patent/WO1993001805A1/fr active IP Right Grant
- 1992-07-21 CA CA002092074A patent/CA2092074C/en not_active Expired - Lifetime
- 1992-07-21 AT AT92917134T patent/ATE148339T1/de active
-
1993
- 1993-03-22 KR KR1019930700863A patent/KR100197465B1/ko not_active IP Right Cessation
-
1997
- 1997-04-29 GR GR970400945T patent/GR3023281T3/el unknown
-
1998
- 1998-06-25 HK HK98106592A patent/HK1007414A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH06502194A (ja) | 1994-03-10 |
EP0548356B1 (fr) | 1997-01-29 |
DE69217191D1 (de) | 1997-03-13 |
KR100197465B1 (en) | 1999-06-15 |
EP0548356A1 (fr) | 1993-06-30 |
CA2092074C (en) | 1998-05-19 |
DE69217191T2 (de) | 1997-08-28 |
HK1007414A1 (en) | 1999-04-09 |
WO1993001805A1 (fr) | 1993-02-04 |
CA2092074A1 (en) | 1993-01-23 |
DK0548356T3 (da) | 1997-08-11 |
AU666666B2 (en) | 1996-02-22 |
GR3023281T3 (en) | 1997-07-30 |
FR2679451B1 (fr) | 1994-09-09 |
JP2820319B2 (ja) | 1998-11-05 |
AU2417192A (en) | 1993-02-23 |
ATE148339T1 (de) | 1997-02-15 |
FR2679451A1 (fr) | 1993-01-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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