ES2099275T3 - Comprimido multiparticulas de desleimiento rapido. - Google Patents

Comprimido multiparticulas de desleimiento rapido.

Info

Publication number
ES2099275T3
ES2099275T3 ES92917134T ES92917134T ES2099275T3 ES 2099275 T3 ES2099275 T3 ES 2099275T3 ES 92917134 T ES92917134 T ES 92917134T ES 92917134 T ES92917134 T ES 92917134T ES 2099275 T3 ES2099275 T3 ES 2099275T3
Authority
ES
Spain
Prior art keywords
multiparticles
compressed
tablet
quick dissolution
imparting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92917134T
Other languages
English (en)
Inventor
Gerard Cousin
Etienne Bruna
Edouard Gendrot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Prographarm SA
Original Assignee
Laboratories Prographarm SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9415391&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2099275(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratories Prographarm SA filed Critical Laboratories Prographarm SA
Application granted granted Critical
Publication of ES2099275T3 publication Critical patent/ES2099275T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

COMPRIMIDO MULTIPARTICULAR DE DESINTEGRACION RAPIDA CUYA MEZCLA DE EXCIPIENTES PERMITE CONFERIR UNA VELOCIDAD DE DESINTEGRACION TAL QUE SU DESAGREGACION EN LA CAVIDAD BUCAL SE PRODUCE EN UN TIEMPO EXTREMADAMENTE CORTO Y PARTICULARMENTE INFERIOR A 60 SEGUNDOS, CARACTERIZADO POR EL HECHO DE QUE LA SUSTANCIA ACTIVA ESTA PRESENTE EN FORMA DE MICROCRISTALES REVESTIDOS O DE MICROGRANULOS REVESTIDOS O NO.
ES92917134T 1991-07-22 1992-07-21 Comprimido multiparticulas de desleimiento rapido. Expired - Lifetime ES2099275T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR919109245A FR2679451B1 (fr) 1991-07-22 1991-07-22 Comprime multiparticulaire a delitement rapide.

Publications (1)

Publication Number Publication Date
ES2099275T3 true ES2099275T3 (es) 1997-05-16

Family

ID=9415391

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92917134T Expired - Lifetime ES2099275T3 (es) 1991-07-22 1992-07-21 Comprimido multiparticulas de desleimiento rapido.

Country Status (12)

Country Link
EP (1) EP0548356B1 (es)
JP (1) JP2820319B2 (es)
KR (1) KR100197465B1 (es)
AT (1) ATE148339T1 (es)
CA (1) CA2092074C (es)
DE (1) DE69217191T2 (es)
DK (1) DK0548356T3 (es)
ES (1) ES2099275T3 (es)
FR (1) FR2679451B1 (es)
GR (1) GR3023281T3 (es)
HK (1) HK1007414A1 (es)
WO (1) WO1993001805A1 (es)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4318577A1 (de) * 1993-06-04 1994-12-08 Merck Patent Gmbh Schmiermittelfreie, arzneimittelhaltige Tabletten
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
DE4333190C2 (de) * 1993-09-29 1996-05-30 Korsatko Werner Univ Prof Dr E Zerbeißtablette mit verzögerter Wirkstoff-Freisetzung
US5807578A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US5807577A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
TW527195B (en) 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
FR2771291B1 (fr) * 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques Spheroides, procede de preparation et compositions pharmaceutiques
AU741992B2 (en) * 1998-03-06 2001-12-13 Adare Pharmaceuticals S.R.L. Fast disintegrating tablets
CN1195500C (zh) 1998-05-18 2005-04-06 武田药品工业株式会社 可口腔崩解的片剂
FR2781793B1 (fr) * 1998-08-03 2001-07-20 Prographarm Lab Procede de fabrication de granules de gabapentine enrobes
FR2785539B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Particules enrobees d'ibuprofene cristallin granule
FR2785538B1 (fr) 1998-11-06 2004-04-09 Prographarm Laboratoires Comprime a delitement rapide perfectionne
FR2790387B1 (fr) 1999-03-01 2001-05-18 Prographarm Laboratoires Comprime orodispersible presentant une faible friabilite et son procede de preparation
GB9908014D0 (en) 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
FR2795962B1 (fr) * 1999-07-08 2003-05-09 Prographarm Laboratoires Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif
DE19931708A1 (de) 1999-07-08 2001-01-18 Bayer Ag Verfahren zur Herstellung schnell zerfallender, fester pharmazeutischer Zubereitungen
ES2366430T3 (es) 2001-06-20 2011-10-20 Takeda Pharmaceutical Company Limited Método para fabricar comprimidos.
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
FR2831820B1 (fr) * 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation
GB0204771D0 (en) * 2002-02-28 2002-04-17 Phoqus Ltd Fast disintegrating tablets
FR2837100B1 (fr) * 2002-03-18 2004-07-23 Flamel Tech Sa Comprimes a bases de microcapsules a liberation modifiee
WO2003084518A2 (fr) 2002-04-09 2003-10-16 Flamel Technologies Suspension orale de microcapsules de principes actifs
US20040005362A1 (en) * 2002-07-03 2004-01-08 Rajneesh Taneja Liquid dosage forms of acid labile drugs
DE10232020A1 (de) 2002-07-04 2004-02-26 Friedrich-Alexander-Universität Erlangen-Nürnberg Neurorezeptoraktive Heteroarencarboxamide
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
FR2861990B1 (fr) 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
DE10359528A1 (de) 2003-12-18 2005-07-28 Schwarz Pharma Ag (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
US20060105039A1 (en) 2004-10-21 2006-05-18 Jin-Wang Lai Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
WO2006085497A1 (ja) * 2005-02-09 2006-08-17 Kissei Pharmaceutical Co., Ltd. 口腔内崩壊錠
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
WO2006133349A2 (en) * 2005-06-08 2006-12-14 Alpharma, Inc. Orally disintegrable sleep aid formulations
PT2046300E (pt) 2006-08-04 2010-07-01 Ethypharm Sa Comprimido multicamadas de desintegraã†o oral
NZ574544A (en) 2006-08-04 2011-12-22 Ethypharm Sa Granule and orally disintegrating tablet comprising oxycodone
JP5366558B2 (ja) 2006-12-28 2013-12-11 武田薬品工業株式会社 口腔内崩壊性固形製剤
JP5228359B2 (ja) * 2007-04-12 2013-07-03 ニプロ株式会社 主薬粒子及びその製造方法ならびに口腔内崩壊錠
FR2920311B1 (fr) * 2007-08-31 2010-06-18 Galenix Innovations Composition solide, orodispersible et/ou dispersible, sans excipient a effet notoire et son procede de preparation
JP2010540588A (ja) 2007-10-01 2010-12-24 ラボラトリオス、レスビ、ソシエダッド、リミターダ 口腔内崩壊錠剤
WO2009113703A2 (en) 2008-03-11 2009-09-17 Takeda Pharmaceutical Company Limited Orally-disintegrating solid preparation
FR2933299B1 (fr) 2008-07-04 2012-02-03 Roquette Freres Mannitol orodispersible
CA2782285A1 (en) 2009-12-02 2011-06-09 Luigi Mapelli Fexofenadine microcapsules and compositions containing them
FR2962550B1 (fr) 2010-07-06 2013-06-14 Ethypharm Sa Methode pour lutter contre la soumission chimique, utilisation d'agent colorant pour lutter contre la soumission chimique et composition pharmaceutique permettant la mise en oeuvre de la methode
FR2962331B1 (fr) 2010-07-06 2020-04-24 Ethypharm Forme pharmaceutique pour lutter contre la soumission chimique, methode la mettant en oeuvre
AU2011350396A1 (en) 2010-12-27 2013-07-11 Takeda Pharmaceutical Company Limited Orally disintegrating tablet
FR2999432B1 (fr) 2012-12-17 2014-12-12 Ethypharm Sa Comprimes orodispersibles obtenus par compression moulage
US10881610B2 (en) 2016-06-16 2021-01-05 Towa Pharmaceutical Co., Ltd. Orally disintegrating tablet
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1200178B (it) * 1986-07-23 1989-01-05 Alfa Farmaceutici Spa Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica
DE3887179T2 (de) * 1987-03-02 1994-06-16 Brocades Pharma Bv Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung.
CA2019324C (en) * 1989-07-10 1996-08-20 Robert L. Jerzewski Fosinopril tablet formulations

Also Published As

Publication number Publication date
JPH06502194A (ja) 1994-03-10
EP0548356B1 (fr) 1997-01-29
DE69217191D1 (de) 1997-03-13
KR100197465B1 (en) 1999-06-15
EP0548356A1 (fr) 1993-06-30
CA2092074C (en) 1998-05-19
DE69217191T2 (de) 1997-08-28
HK1007414A1 (en) 1999-04-09
WO1993001805A1 (fr) 1993-02-04
CA2092074A1 (en) 1993-01-23
DK0548356T3 (da) 1997-08-11
AU666666B2 (en) 1996-02-22
GR3023281T3 (en) 1997-07-30
FR2679451B1 (fr) 1994-09-09
JP2820319B2 (ja) 1998-11-05
AU2417192A (en) 1993-02-23
ATE148339T1 (de) 1997-02-15
FR2679451A1 (fr) 1993-01-29

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