HK1007414A1 - Rapidly disintegratable multiparticulate tablet - Google Patents

Rapidly disintegratable multiparticulate tablet

Info

Publication number
HK1007414A1
HK1007414A1 HK98106592A HK98106592A HK1007414A1 HK 1007414 A1 HK1007414 A1 HK 1007414A1 HK 98106592 A HK98106592 A HK 98106592A HK 98106592 A HK98106592 A HK 98106592A HK 1007414 A1 HK1007414 A1 HK 1007414A1
Authority
HK
Hong Kong
Prior art keywords
tablet
rapidly disintegratable
multiparticulate tablet
disintegratable multiparticulate
rapidly
Prior art date
Application number
HK98106592A
Inventor
Gerard Cousin
Etienne Bruna
Edouard Gendrot
Original Assignee
Prographarm Z I Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9415391&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1007414(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Prographarm Z I Lab filed Critical Prographarm Z I Lab
Publication of HK1007414A1 publication Critical patent/HK1007414A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

A rapidly disintegratable multiparticulate tablet having a mixture of excipients which is suitable for imparting a disintegration rate such that the tablet disintegrates in the mouth in an extremely short time, particularly in less than sixty seconds. The tablet is characterized in that the active substance is present in the form of coated microcrystals or optionally coated microgranules.
HK98106592A 1991-07-22 1998-06-25 Rapidly disintegratable multiparticulate tablet HK1007414A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR919109245A FR2679451B1 (en) 1991-07-22 1991-07-22 MULTIPARTICLE TABLET WITH RAPID DELIVERY.
PCT/FR1992/000715 WO1993001805A1 (en) 1991-07-22 1992-07-21 Rapidly disintegratable multiparticulate tablet

Publications (1)

Publication Number Publication Date
HK1007414A1 true HK1007414A1 (en) 1999-04-09

Family

ID=9415391

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98106592A HK1007414A1 (en) 1991-07-22 1998-06-25 Rapidly disintegratable multiparticulate tablet

Country Status (12)

Country Link
EP (1) EP0548356B1 (en)
JP (1) JP2820319B2 (en)
KR (1) KR100197465B1 (en)
AT (1) ATE148339T1 (en)
CA (1) CA2092074C (en)
DE (1) DE69217191T2 (en)
DK (1) DK0548356T3 (en)
ES (1) ES2099275T3 (en)
FR (1) FR2679451B1 (en)
GR (1) GR3023281T3 (en)
HK (1) HK1007414A1 (en)
WO (1) WO1993001805A1 (en)

Families Citing this family (52)

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DE4318577A1 (en) * 1993-06-04 1994-12-08 Merck Patent Gmbh Lubricant-free, medicament-containing tablets
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
DE4333190C2 (en) * 1993-09-29 1996-05-30 Korsatko Werner Univ Prof Dr E Bite-coated tablet with delayed release of active ingredient
US5807578A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US5807577A (en) * 1995-11-22 1998-09-15 Lab Pharmaceutical Research International Inc. Fast-melt tablet and method of making same
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
FR2766089B1 (en) * 1997-07-21 2000-06-02 Prographarm Lab IMPROVED MULTIPARTICULAR TABLET WITH RAPID DELIVERY
TW527195B (en) 1997-10-09 2003-04-11 Ssp Co Ltd Fast-soluble solid pharmaceutical combinations
FR2771291B1 (en) * 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques SPHEROIDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS
CA2322315C (en) * 1998-03-06 2008-09-16 Eurand International S.P.A. Fast disintegrating tablets
DK1736144T3 (en) 1998-05-18 2015-12-07 Takeda Pharmaceutical Orally disintegrating tablets.
FR2781793B1 (en) * 1998-08-03 2001-07-20 Prographarm Lab PROCESS FOR PRODUCING COATED GABAPENTINE GRANULES
FR2785538B1 (en) * 1998-11-06 2004-04-09 Prographarm Laboratoires PERFECTED QUICK DELIVERY TABLET
FR2785539B1 (en) * 1998-11-06 2004-04-09 Prographarm Laboratoires PARTICLES COATED WITH GRANULATED CRYSTALLINE IBUPROFENE
FR2790387B1 (en) 1999-03-01 2001-05-18 Prographarm Laboratoires ORODISPERSIBLE TABLET HAVING LOW FRIABILITY AND PROCESS FOR THE PREPARATION THEREOF
GB9908014D0 (en) 1999-04-08 1999-06-02 Scherer Corp R P Pharmaceutical compositions
FR2795962B1 (en) * 1999-07-08 2003-05-09 Prographarm Laboratoires PROCESS FOR THE MANUFACTURE OF MASK TASTE COATED GRANULES AND IMMEDIATE RELEASE OF THE ACTIVE INGREDIENT
DE19931708A1 (en) 1999-07-08 2001-01-18 Bayer Ag Process for the preparation of rapidly disintegrating solid pharmaceutical preparations
CA2451135C (en) 2001-06-20 2012-10-09 Takeda Chemical Industries, Ltd. Method of manufacturing tablet
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
FR2831820B1 (en) * 2001-11-05 2004-08-20 Ethypharm Sa ORODISPERSIBLE TABLET HAVING HIGH HOMOGENEITY AND PREPARATION METHOD THEREOF
GB0204771D0 (en) * 2002-02-28 2002-04-17 Phoqus Ltd Fast disintegrating tablets
FR2837100B1 (en) * 2002-03-18 2004-07-23 Flamel Tech Sa MODIFIED RELEASE MICROCAPSULE-BASED TABLETS
ATE419840T1 (en) 2002-04-09 2009-01-15 Flamel Tech Sa ORAL AQUEOUS SUSPENSION CONTAINING MICROCAPSULES FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS
US20040005362A1 (en) * 2002-07-03 2004-01-08 Rajneesh Taneja Liquid dosage forms of acid labile drugs
DE10232020A1 (en) 2002-07-04 2004-02-26 Friedrich-Alexander-Universität Erlangen-Nürnberg Neuroreceptor-active heteroarenecarboxamides
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
FR2861990B1 (en) 2003-11-10 2006-02-10 Nouveaux Produits Pharma LOW DOSAGE TABLETS WITH POLYMER NETWORK
DE10359528A1 (en) 2003-12-18 2005-07-28 Schwarz Pharma Ag (S) -2-N-propylamino-5-hydroxytetralin as a D3 agonist therapeutic
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
CA2584957C (en) 2004-10-21 2015-08-25 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
WO2006085497A1 (en) * 2005-02-09 2006-08-17 Kissei Pharmaceutical Co., Ltd. Tablet disintegrating in the oral cavity
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
WO2006133349A2 (en) * 2005-06-08 2006-12-14 Alpharma, Inc. Orally disintegrable sleep aid formulations
US8465776B2 (en) 2006-08-04 2013-06-18 Ethypharm Granule and orally disintegrating tablet comprising oxycodone
JP5497435B2 (en) 2006-08-04 2014-05-21 エチファーム Multilayer orally disintegrating tablets
WO2008081891A1 (en) 2006-12-28 2008-07-10 Takeda Pharmaceutical Company Limited Orally disintegrating solid preparation
JP5228359B2 (en) * 2007-04-12 2013-07-03 ニプロ株式会社 Active ingredient particles, process for producing the same and orally disintegrating tablets
FR2920311B1 (en) * 2007-08-31 2010-06-18 Galenix Innovations SOLID COMPOSITION, ORODISPERSIBLE AND / OR DISPERSIBLE, WITHOUT A KNOWLEDGE EXCIPIENT AND PROCESS FOR PREPARING THE SAME
KR101626873B1 (en) 2007-10-01 2016-06-02 라보라토리오스 레스비, 에스.엘. orodispersible tablet
WO2009113703A2 (en) 2008-03-11 2009-09-17 Takeda Pharmaceutical Company Limited Orally-disintegrating solid preparation
FR2933299B1 (en) 2008-07-04 2012-02-03 Roquette Freres MANNITOL ORODISPERSIBLE
WO2011067667A2 (en) 2009-12-02 2011-06-09 Eurand Pharmaceuticals Limited Fexofenadine microcapsules and compositions containing them
FR2962331B1 (en) 2010-07-06 2020-04-24 Ethypharm PHARMACEUTICAL FORM FOR COMBATING CHEMICAL SUBMISSION, METHOD USING THE SAME
FR2962550B1 (en) 2010-07-06 2013-06-14 Ethypharm Sa METHOD FOR CONTROLLING CHEMICAL SUBMISSION, USE OF COLORING AGENT FOR COMBATING CHEMICAL SUBMISSION AND PHARMACEUTICAL COMPOSITION FOR THE IMPLEMENTATION OF THE METHOD
CN103402500A (en) 2010-12-27 2013-11-20 武田药品工业株式会社 Orally disintegrating tablet
FR2999432B1 (en) 2012-12-17 2014-12-12 Ethypharm Sa ORODISPERSIBLE COMPRESSES OBTAINED BY COMPRESSION MOLDING
WO2017217494A1 (en) 2016-06-16 2017-12-21 東和薬品株式会社 Orally disintegrating tablet
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1200178B (en) * 1986-07-23 1989-01-05 Alfa Farmaceutici Spa GALENIC FORMULATIONS WITH SCHEDULED SALE CONTAINING DRUGS WITH ANTI-FLOGISTIC ACTIVITY
EP0281200B1 (en) * 1987-03-02 1994-01-19 Yamanouchi Europe B.V. Pharmaceutical composition, pharmaceutical granulate and process for their preparation
CA2019324C (en) * 1989-07-10 1996-08-20 Robert L. Jerzewski Fosinopril tablet formulations

Also Published As

Publication number Publication date
JP2820319B2 (en) 1998-11-05
JPH06502194A (en) 1994-03-10
ATE148339T1 (en) 1997-02-15
DK0548356T3 (en) 1997-08-11
DE69217191D1 (en) 1997-03-13
GR3023281T3 (en) 1997-07-30
CA2092074C (en) 1998-05-19
ES2099275T3 (en) 1997-05-16
AU2417192A (en) 1993-02-23
FR2679451A1 (en) 1993-01-29
WO1993001805A1 (en) 1993-02-04
AU666666B2 (en) 1996-02-22
EP0548356A1 (en) 1993-06-30
FR2679451B1 (en) 1994-09-09
KR100197465B1 (en) 1999-06-15
EP0548356B1 (en) 1997-01-29
DE69217191T2 (en) 1997-08-28
CA2092074A1 (en) 1993-01-23

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Legal Events

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PF Patent in force
PE Patent expired

Effective date: 20120720