ES2098344T3 - Sustrato cromogenico. - Google Patents
Sustrato cromogenico.Info
- Publication number
- ES2098344T3 ES2098344T3 ES91900986T ES91900986T ES2098344T3 ES 2098344 T3 ES2098344 T3 ES 2098344T3 ES 91900986 T ES91900986 T ES 91900986T ES 91900986 T ES91900986 T ES 91900986T ES 2098344 T3 ES2098344 T3 ES 2098344T3
- Authority
- ES
- Spain
- Prior art keywords
- peptide derivatives
- glic
- gli
- determination
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003593 chromogenic compound Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 101000888786 Gloeobacter violaceus (strain ATCC 29082 / PCC 7421) Proton-gated ion channel Proteins 0.000 abstract 2
- 239000002158 endotoxin Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- TYMLOMAKGOJONV-UHFFFAOYSA-N 4-nitroaniline Chemical compound NC1=CC=C([N+]([O-])=O)C=C1 TYMLOMAKGOJONV-UHFFFAOYSA-N 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Photoreceptors In Electrophotography (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Luminescent Compositions (AREA)
Abstract
SUBSTRATO CROMOGENETICO. LA INVENCION ESTA RELACIONADA CON DERIVADOS DE PEPTIDOS NUEVOS CON LA FORMULA: R1-A1-A2-A3-A4-R2 O SU SAL, EN DONDE R1 = H O A UN GRUPO PROTECTOR; A1 = H, ILE, LEU O VAL; A2 = GLU, ASP, SER, THR; A3 = GLI O GLIC; A4 = 4-NITRO ANILINA CON LA CONDICION DE QUE A3 SEA GLI CUANDO A4 ES LIS Y QUE A3 SEA GLIC CUANDO A4 ES ARG. LA INVENCION TAMBIEN DESVELA EL PROCESO PARA LA PREPARACION DE LOS DERIVADOS DE PEPTIDOS, EL METODO PARA LA DETERMINACION DE LAS ENDOTOXINAS BACTERIANAS POR EL EMPLEO DE LOS DERIVADOS DE PEPTIDOS INVENTADOS Y EL EMPLEO DE ESTOS DERIVADOS PARA LA DETERMINACION DE ENDOTOXINAS BACTERIANAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8904188A SE8904188D0 (sv) | 1989-12-12 | 1989-12-12 | Chromogenic substrate |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2098344T3 true ES2098344T3 (es) | 1997-05-01 |
Family
ID=20377747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91900986T Expired - Lifetime ES2098344T3 (es) | 1989-12-12 | 1990-12-03 | Sustrato cromogenico. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5334703A (es) |
EP (1) | EP0505428B1 (es) |
JP (1) | JP2929555B2 (es) |
AT (1) | ATE149516T1 (es) |
AU (1) | AU6957991A (es) |
DE (1) | DE69030102T2 (es) |
ES (1) | ES2098344T3 (es) |
SE (1) | SE8904188D0 (es) |
WO (1) | WO1991009052A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69211973T2 (de) * | 1991-12-25 | 1996-12-19 | Maruha Corp | Reagenzien und Verfahren zur Bestimmung von Beta-Glucanen |
DE10251894A1 (de) * | 2002-11-07 | 2004-05-19 | C-Cit Ag | Peptidgebundene Chromogene zur Bestimmung von Enzymaktivitäten |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3759218A (en) * | 1971-08-03 | 1973-09-18 | H Korstvedt | Breading apparatus |
JPS5415797A (en) * | 1977-06-14 | 1979-02-05 | Seikagaku Kogyo Co Ltd | Detection and measurement of toxin in cells |
SE7801373L (sv) * | 1978-02-07 | 1979-08-08 | Kabi Ab | Lett spjelkbara substrat for kvantifiering av proteaser |
US4244865A (en) * | 1979-12-03 | 1981-01-13 | Abbott Laboratories | α hydroxy tripeptide substrates |
WO1982000641A1 (en) * | 1980-08-25 | 1982-03-04 | Ab Kabivitrum | Peptide substrates for determination of protease activity |
US4563305A (en) * | 1981-01-07 | 1986-01-07 | University Of Miami | Radiolabelled substrates for assaying mammalian enzymes |
FR2497798A1 (fr) * | 1981-01-09 | 1982-07-16 | Pharmindustrie | Nouveaux peptides portant un fluorophore, procede pour leur preparation et leur application au dosage fluorimetrique des endotoxines |
US4510241A (en) * | 1981-09-03 | 1985-04-09 | Mallinckrodt, Inc. | Peptide-type substrates useful in the quantitative determination of endotoxin |
JPS5885162A (ja) * | 1981-11-16 | 1983-05-21 | Seikagaku Kogyo Co Ltd | エンドトキシン測定法 |
SE431228B (sv) * | 1981-12-17 | 1984-01-23 | Kenneth Soderhell | Sett att bestemma bakteriella endotoxin medelst profenoloxidashaltigt blodkroppslysat fran kreftdjur eller insekter och reagens herfor |
DE3244030A1 (de) * | 1982-11-27 | 1984-05-30 | Behringwerke Ag, 3550 Marburg | Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung |
JPS62236474A (ja) * | 1986-04-08 | 1987-10-16 | San Plant Kogyo Kk | 自動粉付機 |
JPS62294027A (ja) * | 1986-06-11 | 1987-12-21 | サン・プラント工業株式会社 | ロ−ラ−状粉搬送機 |
-
1989
- 1989-12-12 SE SE8904188A patent/SE8904188D0/xx unknown
-
1990
- 1990-12-03 AU AU69579/91A patent/AU6957991A/en not_active Abandoned
- 1990-12-03 DE DE69030102T patent/DE69030102T2/de not_active Expired - Fee Related
- 1990-12-03 AT AT91900986T patent/ATE149516T1/de not_active IP Right Cessation
- 1990-12-03 WO PCT/SE1990/000797 patent/WO1991009052A1/en active IP Right Grant
- 1990-12-03 JP JP3501386A patent/JP2929555B2/ja not_active Expired - Lifetime
- 1990-12-03 US US07/859,717 patent/US5334703A/en not_active Expired - Fee Related
- 1990-12-03 EP EP91900986A patent/EP0505428B1/en not_active Expired - Lifetime
- 1990-12-03 ES ES91900986T patent/ES2098344T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1991009052A1 (en) | 1991-06-27 |
DE69030102T2 (de) | 1997-07-17 |
EP0505428B1 (en) | 1997-03-05 |
DE69030102D1 (en) | 1997-04-10 |
US5334703A (en) | 1994-08-02 |
SE8904188D0 (sv) | 1989-12-12 |
JP2929555B2 (ja) | 1999-08-03 |
EP0505428A1 (en) | 1992-09-30 |
JPH05506209A (ja) | 1993-09-16 |
AU6957991A (en) | 1991-07-18 |
ATE149516T1 (de) | 1997-03-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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