ES2098080T3 - Procedimiento para la obtencion de un derivado de n-tert-butilisoquinolin-3-carboxamida y compuestos intermedios de este procedimiento. - Google Patents

Procedimiento para la obtencion de un derivado de n-tert-butilisoquinolin-3-carboxamida y compuestos intermedios de este procedimiento.

Info

Publication number
ES2098080T3
ES2098080T3 ES94110247T ES94110247T ES2098080T3 ES 2098080 T3 ES2098080 T3 ES 2098080T3 ES 94110247 T ES94110247 T ES 94110247T ES 94110247 T ES94110247 T ES 94110247T ES 2098080 T3 ES2098080 T3 ES 2098080T3
Authority
ES
Spain
Prior art keywords
procedure
phenyl
carboxamide
phthalimido
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94110247T
Other languages
English (en)
Inventor
Hans Hilpert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2098080T3 publication Critical patent/ES2098080T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

PROCESO PARA LA ELABORACION DEL N (4AS,8AS) TRAVES DE AMINACION REDUCTIVA DE LOS ALFA-HIDROXIALDEHIDOS QUE CORRESPONDE AL ALCOHOL I; PROCESO PARA LA ELABORACION DE LOS PRODUCTOS CORRESPONDIENTES A ESTE ALFA-HIDROXIALDEHIDO, ASI COMO NUEVOS PRODUCTOS INTERMEDIOS QUE APARECEN EN EL PROCESO.
ES94110247T 1993-07-15 1994-07-01 Procedimiento para la obtencion de un derivado de n-tert-butilisoquinolin-3-carboxamida y compuestos intermedios de este procedimiento. Expired - Lifetime ES2098080T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH213293 1993-07-15
CH233093 1993-08-04

Publications (1)

Publication Number Publication Date
ES2098080T3 true ES2098080T3 (es) 1997-04-16

Family

ID=25689603

Family Applications (2)

Application Number Title Priority Date Filing Date
ES96112342T Expired - Lifetime ES2125077T3 (es) 1993-07-15 1994-07-01 Procedimiento de obtencion de una n-tert-butilamida.
ES94110247T Expired - Lifetime ES2098080T3 (es) 1993-07-15 1994-07-01 Procedimiento para la obtencion de un derivado de n-tert-butilisoquinolin-3-carboxamida y compuestos intermedios de este procedimiento.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES96112342T Expired - Lifetime ES2125077T3 (es) 1993-07-15 1994-07-01 Procedimiento de obtencion de una n-tert-butilamida.

Country Status (8)

Country Link
US (3) US5502210A (es)
EP (2) EP0634410B1 (es)
JP (1) JP2531935B2 (es)
CN (2) CN1046510C (es)
AT (2) ATE172970T1 (es)
DE (2) DE59407243D1 (es)
DK (2) DK0634410T3 (es)
ES (2) ES2125077T3 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591885A (en) * 1994-09-23 1997-01-07 Hoffman-La Roche Inc. Process for the preparation of halogenated α-aminoketone compounds
US5831117A (en) * 1995-01-20 1998-11-03 G. D. Searle & Co. Method of preparing retroviral protease inhibitor intermediates
DK0847994T3 (da) 1996-12-11 2003-07-28 Hoffmann La Roche Fremgangsmåde til fremstilling af blandede anhydrider
DE60034158T2 (de) 1999-06-22 2007-12-13 Fujifilm Corp. Verfahren und Apparat zum Wickeln von Film, Verfahren und Apparat zum Zuführen von Wickelkernen und Verfahren und Apparat zum Kontrollieren des Zustandes von Filmrollen
US6916254B2 (en) * 2003-01-02 2005-07-12 Acushnet Company Golf ball with small inner core

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61227578A (ja) * 1985-03-30 1986-10-09 Neos Co Ltd １，３，２―ジオキサチオラン―２―オキシド誘導体およびその製法
JPH0692427B2 (ja) * 1989-07-11 1994-11-16 高砂香料工業株式会社 ２，２’―ビス（ジシクロヘキシルホスフィノ）―６，６’―ジメチル―１，１’―ビフェニルを配位子とする錯体，およびその錯体を用いた有機カルボン酸とそのエステルの製造方法
GB8927915D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Novel alcohols
GB8927913D0 (en) 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
DK0579797T3 (da) * 1992-01-31 1999-10-25 Hoffmann La Roche Diphosphinligander

Also Published As

Publication number Publication date
ATE172970T1 (de) 1998-11-15
DK0634410T3 (da) 1997-06-02
US5698698A (en) 1997-12-16
CN1046510C (zh) 1999-11-17
DE59407243D1 (de) 1998-12-10
ATE149162T1 (de) 1997-03-15
JP2531935B2 (ja) 1996-09-04
DE59401846D1 (de) 1997-04-03
EP0634410B1 (de) 1997-02-26
US5641886A (en) 1997-06-24
US5502210A (en) 1996-03-26
ES2125077T3 (es) 1999-02-16
EP0738724A3 (de) 1997-02-19
CN1215056A (zh) 1999-04-28
CN1104641A (zh) 1995-07-05
DK0738724T3 (da) 1999-07-19
EP0738724B1 (de) 1998-11-04
JPH0753547A (ja) 1995-02-28
EP0634410A1 (de) 1995-01-18
EP0738724A2 (de) 1996-10-23

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