DK0634410T3 - Fremgangsmåde til fremstilling af et N-tert.butylisoquinolin-3-carboxamidderivat og mellemprodukter til denne fremgangsmåde - Google Patents

Fremgangsmåde til fremstilling af et N-tert.butylisoquinolin-3-carboxamidderivat og mellemprodukter til denne fremgangsmåde

Info

Publication number
DK0634410T3
DK0634410T3 DK94110247.7T DK94110247T DK0634410T3 DK 0634410 T3 DK0634410 T3 DK 0634410T3 DK 94110247 T DK94110247 T DK 94110247T DK 0634410 T3 DK0634410 T3 DK 0634410T3
Authority
DK
Denmark
Prior art keywords
phenyl
phthalimido
reacting
formula
butylisoquinoline
Prior art date
Application number
DK94110247.7T
Other languages
English (en)
Inventor
Hans Hilpert
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0634410T3 publication Critical patent/DK0634410T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D411/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
DK94110247.7T 1993-07-15 1994-07-01 Fremgangsmåde til fremstilling af et N-tert.butylisoquinolin-3-carboxamidderivat og mellemprodukter til denne fremgangsmåde DK0634410T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH213293 1993-07-15
CH233093 1993-08-04

Publications (1)

Publication Number Publication Date
DK0634410T3 true DK0634410T3 (da) 1997-06-02

Family

ID=25689603

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96112342T DK0738724T3 (da) 1993-07-15 1994-07-01 Fremgangsmåde til fremstilling af et N-tert.butylamid
DK94110247.7T DK0634410T3 (da) 1993-07-15 1994-07-01 Fremgangsmåde til fremstilling af et N-tert.butylisoquinolin-3-carboxamidderivat og mellemprodukter til denne fremgangsmåde

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK96112342T DK0738724T3 (da) 1993-07-15 1994-07-01 Fremgangsmåde til fremstilling af et N-tert.butylamid

Country Status (8)

Country Link
US (3) US5502210A (da)
EP (2) EP0738724B1 (da)
JP (1) JP2531935B2 (da)
CN (2) CN1046510C (da)
AT (2) ATE149162T1 (da)
DE (2) DE59407243D1 (da)
DK (2) DK0738724T3 (da)
ES (2) ES2125077T3 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591885A (en) * 1994-09-23 1997-01-07 Hoffman-La Roche Inc. Process for the preparation of halogenated α-aminoketone compounds
US5831117A (en) * 1995-01-20 1998-11-03 G. D. Searle & Co. Method of preparing retroviral protease inhibitor intermediates
ES2194145T3 (es) 1996-12-11 2003-11-16 Hoffmann La Roche Procedimiento para la obtencion de anhidridos mixtos.
DE60033868T2 (de) 1999-06-22 2007-11-08 Fujifilm Corp. Verfahren und Apparat zum Wickeln von Film, Verfahren und Apparat zum Zuführen von Wickelkernen und Verfahren und Apparat zum Kontrollieren des Zustandes von Filmrollen
US6916254B2 (en) * 2003-01-02 2005-07-12 Acushnet Company Golf ball with small inner core

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61227578A (ja) * 1985-03-30 1986-10-09 Neos Co Ltd 1,3,2―ジオキサチオラン―2―オキシド誘導体およびその製法
JPH0692427B2 (ja) * 1989-07-11 1994-11-16 高砂香料工業株式会社 2,2’―ビス(ジシクロヘキシルホスフィノ)―6,6’―ジメチル―1,1’―ビフェニルを配位子とする錯体,およびその錯体を用いた有機カルボン酸とそのエステルの製造方法
GB8927915D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Novel alcohols
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
US5457219A (en) * 1992-01-31 1995-10-10 Hoffmann-La Roche Inc. Phosphorus compounds

Also Published As

Publication number Publication date
CN1104641A (zh) 1995-07-05
ES2125077T3 (es) 1999-02-16
CN1046510C (zh) 1999-11-17
EP0634410B1 (de) 1997-02-26
EP0738724B1 (de) 1998-11-04
ATE149162T1 (de) 1997-03-15
ES2098080T3 (es) 1997-04-16
US5698698A (en) 1997-12-16
EP0738724A2 (de) 1996-10-23
EP0738724A3 (de) 1997-02-19
DE59407243D1 (de) 1998-12-10
CN1215056A (zh) 1999-04-28
JP2531935B2 (ja) 1996-09-04
DE59401846D1 (de) 1997-04-03
US5641886A (en) 1997-06-24
DK0738724T3 (da) 1999-07-19
JPH0753547A (ja) 1995-02-28
EP0634410A1 (de) 1995-01-18
US5502210A (en) 1996-03-26
ATE172970T1 (de) 1998-11-15

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