ES2097952T3 - Comprimidos de liberacion programada que contienen naproxeno. - Google Patents

Comprimidos de liberacion programada que contienen naproxeno.

Info

Publication number
ES2097952T3
ES2097952T3 ES93114151T ES93114151T ES2097952T3 ES 2097952 T3 ES2097952 T3 ES 2097952T3 ES 93114151 T ES93114151 T ES 93114151T ES 93114151 T ES93114151 T ES 93114151T ES 2097952 T3 ES2097952 T3 ES 2097952T3
Authority
ES
Spain
Prior art keywords
naxoprene
period
tablets containing
release tablets
pills
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93114151T
Other languages
English (en)
Inventor
Egidio Marchi
Leone Gabriele Rotini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Wasserman SpA
Original Assignee
Alfa Wasserman SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wasserman SpA filed Critical Alfa Wasserman SpA
Application granted granted Critical
Publication of ES2097952T3 publication Critical patent/ES2097952T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE DESCRIBEN UNAS PASTILLAS DE ACCION CONTROLADA, PARA SER ADMINISTRADAS POR VIA ORAL, QUE CONTIENEN DE 500 A 1200 MG DE NAXOPRENO, HECHO DE MEZCLAS DE UN GRANULADO DE ACCION INMEDIATA SECO EN COMPACTO QUE CONTIENE DE 5 A 28% DE NAXOPRENO, DE UN GRANULADO DE ACCION CONTROLADA SECO EN COMPACTO DE 72 A 95% DE NAXOPRENO Y UN AGENTE DESINTEGRADOR. UNA PARTE DEL NAXOPRENO SE LIBERA EN UN PERIODO CORTO DE TIEMPO, DE FORMA QUE LA DROGA PUEDE DESARROLLAR RAPIDAMENTE SU ACCION TERAPEUTICA ALCANZANDO LOS NIVELES HEMATICOS NECESARIOS, MIENTRAS LA PORCION RESTANTE SE LIBERA EN UN INTERVALO MEDIO DE TIEMPO DE FORMA QUE PERMITE LA COBERTURA TERAPEUTICA HASTA LA SIGUIENTE ADMINISTRACION. LA COVERTURA TERAPEUTICA ES EFECTIVA POR UN PERIODO DE 24H; ENTONCES LAS PASTILLAS OBJETO DE LA INVENCION SON APROPIADAS PARA UNA SOLA ADMINISTRACION DIARIA.
ES93114151T 1992-09-11 1993-09-03 Comprimidos de liberacion programada que contienen naproxeno. Expired - Lifetime ES2097952T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITBO920315A IT1258143B (it) 1992-09-11 1992-09-11 Compresse a cessione programmata contenenti naproxen

Publications (1)

Publication Number Publication Date
ES2097952T3 true ES2097952T3 (es) 1997-04-16

Family

ID=11338458

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93114151T Expired - Lifetime ES2097952T3 (es) 1992-09-11 1993-09-03 Comprimidos de liberacion programada que contienen naproxeno.

Country Status (20)

Country Link
US (1) US5480650A (es)
EP (1) EP0587065B1 (es)
KR (1) KR970008157B1 (es)
CN (1) CN1088091A (es)
AT (1) ATE148340T1 (es)
AU (1) AU669552B2 (es)
CA (1) CA2105541C (es)
CZ (1) CZ279853B6 (es)
DE (1) DE69307807T2 (es)
DK (1) DK0587065T3 (es)
ES (1) ES2097952T3 (es)
FI (1) FI933975A (es)
GR (1) GR3022434T3 (es)
IL (1) IL106943A (es)
IS (1) IS1624B (es)
IT (1) IT1258143B (es)
MX (1) MX9305445A (es)
NO (1) NO304260B1 (es)
NZ (1) NZ248574A (es)
ZA (1) ZA936445B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5609884A (en) * 1992-08-31 1997-03-11 G. D. Searle & Co. Controlled release naproxen sodium plus naproxen combination tablet
US8022095B2 (en) * 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US6153225A (en) * 1998-08-13 2000-11-28 Elan Pharma International Limited Injectable formulations of nanoparticulate naproxen
US6165506A (en) * 1998-09-04 2000-12-26 Elan Pharma International Ltd. Solid dose form of nanoparticulate naproxen
CN1434704A (zh) * 1999-12-16 2003-08-06 三叉技术有限责任公司 延长其受体负荷剂量的治疗剂释放的系统和方法
WO2004060355A1 (en) * 2002-12-26 2004-07-22 Pozen Inc. Multilayer Dosage Forms Containing NSAIDs and Triptans
US8481565B2 (en) 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
EA201071035A1 (ru) * 2008-03-05 2011-04-29 Панацеа Биотек Лимитед Фармацевтические композиции модифицированного высвобождения, содержащие микофенолат, и способ их получения
US20090252791A1 (en) * 2008-04-02 2009-10-08 Venkata Nookaraju Sreedharala Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
US20090311335A1 (en) * 2008-06-12 2009-12-17 Scott Jenkins Combination of a triptan and an nsaid
US8618157B2 (en) * 2008-06-20 2013-12-31 Alphapharm Pty. Ltd. Pharmaceutical formulation
ES2821528T3 (es) 2012-11-14 2021-04-26 Grace W R & Co Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1200178B (it) * 1986-07-23 1989-01-05 Alfa Farmaceutici Spa Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica
IT1215726B (it) * 1988-01-18 1990-02-22 Alfa Wassermann Spa Formulazioni galeniche a cessione programmata.
US5232705A (en) * 1990-08-31 1993-08-03 Alza Corporation Dosage form for time-varying patterns of drug delivery
US5204116A (en) * 1991-05-01 1993-04-20 Alza Corporation Dosage form providing immediate therapy followed by prolonged therapy

Also Published As

Publication number Publication date
NO933177L (no) 1994-03-14
KR970008157B1 (ko) 1997-05-21
KR940006577A (ko) 1994-04-25
DE69307807D1 (de) 1997-03-13
IS1624B (is) 1996-10-18
MX9305445A (es) 1994-05-31
NO933177D0 (no) 1993-09-07
EP0587065B1 (en) 1997-01-29
IS4069A (is) 1994-03-12
CN1088091A (zh) 1994-06-22
DK0587065T3 (da) 1997-06-09
CZ279853B6 (cs) 1995-07-12
CA2105541A1 (en) 1994-03-12
NO304260B1 (no) 1998-11-23
GR3022434T3 (en) 1997-04-30
AU669552B2 (en) 1996-06-13
ITBO920315A1 (it) 1994-03-11
AU4620293A (en) 1994-03-17
DE69307807T2 (de) 1997-05-15
ZA936445B (en) 1995-01-31
EP0587065A1 (en) 1994-03-16
FI933975A0 (fi) 1993-09-10
NZ248574A (en) 1995-04-27
IL106943A (en) 1998-09-24
CA2105541C (en) 1999-01-05
FI933975A (fi) 1994-03-12
US5480650A (en) 1996-01-02
IT1258143B (it) 1996-02-20
ATE148340T1 (de) 1997-02-15
ITBO920315A0 (it) 1992-09-11
CZ180693A3 (en) 1994-03-16

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