ES2097952T3 - Comprimidos de liberacion programada que contienen naproxeno. - Google Patents
Comprimidos de liberacion programada que contienen naproxeno.Info
- Publication number
- ES2097952T3 ES2097952T3 ES93114151T ES93114151T ES2097952T3 ES 2097952 T3 ES2097952 T3 ES 2097952T3 ES 93114151 T ES93114151 T ES 93114151T ES 93114151 T ES93114151 T ES 93114151T ES 2097952 T3 ES2097952 T3 ES 2097952T3
- Authority
- ES
- Spain
- Prior art keywords
- naxoprene
- period
- tablets containing
- release tablets
- pills
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 title 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical compound C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 title 1
- 229960002009 naproxen Drugs 0.000 title 1
- 239000006187 pill Substances 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
SE DESCRIBEN UNAS PASTILLAS DE ACCION CONTROLADA, PARA SER ADMINISTRADAS POR VIA ORAL, QUE CONTIENEN DE 500 A 1200 MG DE NAXOPRENO, HECHO DE MEZCLAS DE UN GRANULADO DE ACCION INMEDIATA SECO EN COMPACTO QUE CONTIENE DE 5 A 28% DE NAXOPRENO, DE UN GRANULADO DE ACCION CONTROLADA SECO EN COMPACTO DE 72 A 95% DE NAXOPRENO Y UN AGENTE DESINTEGRADOR. UNA PARTE DEL NAXOPRENO SE LIBERA EN UN PERIODO CORTO DE TIEMPO, DE FORMA QUE LA DROGA PUEDE DESARROLLAR RAPIDAMENTE SU ACCION TERAPEUTICA ALCANZANDO LOS NIVELES HEMATICOS NECESARIOS, MIENTRAS LA PORCION RESTANTE SE LIBERA EN UN INTERVALO MEDIO DE TIEMPO DE FORMA QUE PERMITE LA COBERTURA TERAPEUTICA HASTA LA SIGUIENTE ADMINISTRACION. LA COVERTURA TERAPEUTICA ES EFECTIVA POR UN PERIODO DE 24H; ENTONCES LAS PASTILLAS OBJETO DE LA INVENCION SON APROPIADAS PARA UNA SOLA ADMINISTRACION DIARIA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITBO920315A IT1258143B (it) | 1992-09-11 | 1992-09-11 | Compresse a cessione programmata contenenti naproxen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2097952T3 true ES2097952T3 (es) | 1997-04-16 |
Family
ID=11338458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES93114151T Expired - Lifetime ES2097952T3 (es) | 1992-09-11 | 1993-09-03 | Comprimidos de liberacion programada que contienen naproxeno. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5480650A (es) |
| EP (1) | EP0587065B1 (es) |
| KR (1) | KR970008157B1 (es) |
| CN (1) | CN1088091A (es) |
| AT (1) | ATE148340T1 (es) |
| AU (1) | AU669552B2 (es) |
| CA (1) | CA2105541C (es) |
| CZ (1) | CZ279853B6 (es) |
| DE (1) | DE69307807T2 (es) |
| DK (1) | DK0587065T3 (es) |
| ES (1) | ES2097952T3 (es) |
| FI (1) | FI933975A (es) |
| GR (1) | GR3022434T3 (es) |
| IL (1) | IL106943A (es) |
| IS (1) | IS1624B (es) |
| IT (1) | IT1258143B (es) |
| MX (1) | MX9305445A (es) |
| NO (1) | NO304260B1 (es) |
| NZ (1) | NZ248574A (es) |
| ZA (1) | ZA936445B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5609884A (en) * | 1992-08-31 | 1997-03-11 | G. D. Searle & Co. | Controlled release naproxen sodium plus naproxen combination tablet |
| US8022095B2 (en) * | 1996-08-16 | 2011-09-20 | Pozen, Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
| US6153225A (en) * | 1998-08-13 | 2000-11-28 | Elan Pharma International Limited | Injectable formulations of nanoparticulate naproxen |
| US6165506A (en) * | 1998-09-04 | 2000-12-26 | Elan Pharma International Ltd. | Solid dose form of nanoparticulate naproxen |
| WO2001043726A1 (en) * | 1999-12-16 | 2001-06-21 | Trident Technologies, Llc | System and method for extended delivery of a therapeutic agent with its receptor loading dose |
| EP1575566B1 (en) * | 2002-12-26 | 2012-02-22 | Pozen, Inc. | Multilayer dosage forms containing naproxen and triptans |
| US8481565B2 (en) | 2004-12-27 | 2013-07-09 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
| EA201071035A1 (ru) * | 2008-03-05 | 2011-04-29 | Панацеа Биотек Лимитед | Фармацевтические композиции модифицированного высвобождения, содержащие микофенолат, и способ их получения |
| US20090252791A1 (en) * | 2008-04-02 | 2009-10-08 | Venkata Nookaraju Sreedharala | Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug |
| US20090311335A1 (en) * | 2008-06-12 | 2009-12-17 | Scott Jenkins | Combination of a triptan and an nsaid |
| CN102088966B (zh) * | 2008-06-20 | 2015-06-10 | 阿尔法制药有限公司 | 药物制剂 |
| EP2919903B1 (en) | 2012-11-14 | 2020-07-22 | W.R. Grace & CO. - CONN. | Compositions containing a biologically active material and a non-ordered inorganic oxide |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1200178B (it) * | 1986-07-23 | 1989-01-05 | Alfa Farmaceutici Spa | Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica |
| IT1215726B (it) * | 1988-01-18 | 1990-02-22 | Alfa Wassermann Spa | Formulazioni galeniche a cessione programmata. |
| US5232705A (en) * | 1990-08-31 | 1993-08-03 | Alza Corporation | Dosage form for time-varying patterns of drug delivery |
| US5204116A (en) * | 1991-05-01 | 1993-04-20 | Alza Corporation | Dosage form providing immediate therapy followed by prolonged therapy |
-
1992
- 1992-09-11 IT ITBO920315A patent/IT1258143B/it active IP Right Grant
-
1993
- 1993-09-01 IS IS4069A patent/IS1624B/is unknown
- 1993-09-01 ZA ZA936445A patent/ZA936445B/xx unknown
- 1993-09-01 CZ CZ931806A patent/CZ279853B6/cs not_active IP Right Cessation
- 1993-09-01 US US08/115,897 patent/US5480650A/en not_active Expired - Fee Related
- 1993-09-02 NZ NZ248574A patent/NZ248574A/en unknown
- 1993-09-03 ES ES93114151T patent/ES2097952T3/es not_active Expired - Lifetime
- 1993-09-03 AT AT93114151T patent/ATE148340T1/de not_active IP Right Cessation
- 1993-09-03 DK DK93114151.9T patent/DK0587065T3/da active
- 1993-09-03 EP EP93114151A patent/EP0587065B1/en not_active Expired - Lifetime
- 1993-09-03 DE DE69307807T patent/DE69307807T2/de not_active Expired - Fee Related
- 1993-09-03 CA CA002105541A patent/CA2105541C/en not_active Expired - Fee Related
- 1993-09-06 MX MX9305445A patent/MX9305445A/es not_active IP Right Cessation
- 1993-09-07 NO NO933177A patent/NO304260B1/no not_active IP Right Cessation
- 1993-09-07 IL IL10694393A patent/IL106943A/en not_active IP Right Cessation
- 1993-09-08 AU AU46202/93A patent/AU669552B2/en not_active Ceased
- 1993-09-08 CN CN93116664A patent/CN1088091A/zh active Pending
- 1993-09-10 KR KR1019930018163A patent/KR970008157B1/ko not_active IP Right Cessation
- 1993-09-10 FI FI933975A patent/FI933975A/fi not_active Application Discontinuation
-
1997
- 1997-01-30 GR GR970400110T patent/GR3022434T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1088091A (zh) | 1994-06-22 |
| KR970008157B1 (ko) | 1997-05-21 |
| GR3022434T3 (en) | 1997-04-30 |
| IS1624B (is) | 1996-10-18 |
| KR940006577A (ko) | 1994-04-25 |
| DK0587065T3 (da) | 1997-06-09 |
| IT1258143B (it) | 1996-02-20 |
| CZ180693A3 (en) | 1994-03-16 |
| NO304260B1 (no) | 1998-11-23 |
| ITBO920315A1 (it) | 1994-03-11 |
| NO933177D0 (no) | 1993-09-07 |
| ITBO920315A0 (it) | 1992-09-11 |
| ATE148340T1 (de) | 1997-02-15 |
| DE69307807D1 (de) | 1997-03-13 |
| CA2105541A1 (en) | 1994-03-12 |
| DE69307807T2 (de) | 1997-05-15 |
| ZA936445B (en) | 1995-01-31 |
| NZ248574A (en) | 1995-04-27 |
| AU4620293A (en) | 1994-03-17 |
| AU669552B2 (en) | 1996-06-13 |
| EP0587065A1 (en) | 1994-03-16 |
| FI933975A0 (fi) | 1993-09-10 |
| FI933975A (fi) | 1994-03-12 |
| MX9305445A (es) | 1994-05-31 |
| IS4069A (is) | 1994-03-12 |
| EP0587065B1 (en) | 1997-01-29 |
| IL106943A (en) | 1998-09-24 |
| CZ279853B6 (cs) | 1995-07-12 |
| NO933177L (no) | 1994-03-14 |
| CA2105541C (en) | 1999-01-05 |
| US5480650A (en) | 1996-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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