ES2095073T3 - Procedimiento para la fabricacion de derivados de acido cinamico. - Google Patents

Procedimiento para la fabricacion de derivados de acido cinamico.

Info

Publication number
ES2095073T3
ES2095073T3 ES93919198T ES93919198T ES2095073T3 ES 2095073 T3 ES2095073 T3 ES 2095073T3 ES 93919198 T ES93919198 T ES 93919198T ES 93919198 T ES93919198 T ES 93919198T ES 2095073 T3 ES2095073 T3 ES 2095073T3
Authority
ES
Spain
Prior art keywords
manufacture
pct
alkanoic
alkyl
add
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93919198T
Other languages
English (en)
Inventor
Peter Gygax
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Givaudan SA
Original Assignee
Givaudan Roure International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Roure International SA filed Critical Givaudan Roure International SA
Application granted granted Critical
Publication of ES2095073T3 publication Critical patent/ES2095073T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

SE DESCRIBE UN NUEVO PROCESO PARA LA PRODUCCION DE UN DERIVADO DEL ACIDO CINAMICO DE LA FORMULA (I) EN LA QUE R1 SIGNIFICA HIDROGENO O ALKILO C1-8 Y R2 SIGNIFICA HIDROGENO, ALKILO C1-10, HIDROXIALKILO C110 O HIDROXIALKILO C1-4 O ALCOXI C1-4 ALKILO C1-10, EN QUE SE HACE REACCIONAR 4-R1O-HALOBENCENO CON ACIDO ACRILICO O UN ESTER DEL ACIDO ACRILICO CH2 = CHCOOR2 UTILIZANDO UN CATALIZADOR DE PALADIO HETEROGENEO EN PRESENCIA DE LA SAL DE AMONIO DEL ACIDO ALCANOICO FORMADA A PARTIR DE UN ACIDO ALCANOICO C2-5 Y UNA MONO-, DIINA HETEROCICLICA. EN EL CASO DE LA PRODUCCION DEL DERIVADO DEL ACIDO CINAMICO (I) EN QUE R2 SIGNIFICA HIDROGENO, LA REACCION SE PUEDE LLEVAR A CABO EN PRESENCIA DE LA AMINA EN LUGAR DE LA SAL DE AMONIO DEL ACIDO ALCANOICO. OTRO ASPECTO DE LA INVENCION DESCRIBA CONSISTE EN HACER REACCIONAR EL 4-R1OYODOBENCENO CON EL PRODUCTO DE LA ADICION DE MICHAEL DE UN ESTER DEL ACIDO ACRILICO CH2 = CHCOOR2'', EN DONDE R2'' SIGNIFICA LO MISMO QUE EL R2 ARRIBA MENCIONADO EXCEPTO HIDROGENO, CONUNA AMINA PRIMARIA O SECUNDARIA ALIFATICA O HETEROCICLICA UTILIZANDO UN CATALIZADOR DE PALADIO HETEROGENEO Y EN PRESENCIA DE UN ACIDO ALCANOICO C2.5 PARA LA PRODUCCION DE LOS DERIVADOS DEL ACIDO CINAMICO ANTEDICHOS CON LA EXCEPCION DEL ACIDO CINAMICO MISMO SUSTITUIDO. A LA VISTA DE SUS PROPIEDADES DE ABSORCION DE UV-B LOS DERIVADOS DEL ACIDO CINAMICO ASI PRODUCIDOS SON UTILES COMO FILTROS DE UV-B PARA AGENTES COSMETICOS, EJ. AGENTES PROTECTORES DEL SOL.
ES93919198T 1992-09-03 1993-08-27 Procedimiento para la fabricacion de derivados de acido cinamico. Expired - Lifetime ES2095073T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH277192 1992-09-03
EP93111812 1993-07-23

Publications (1)

Publication Number Publication Date
ES2095073T3 true ES2095073T3 (es) 1997-02-01

Family

ID=25691362

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93919198T Expired - Lifetime ES2095073T3 (es) 1992-09-03 1993-08-27 Procedimiento para la fabricacion de derivados de acido cinamico.

Country Status (10)

Country Link
US (1) US5457226A (es)
EP (1) EP0612310B1 (es)
JP (1) JP3539730B2 (es)
AT (1) ATE144242T1 (es)
AU (1) AU659570B2 (es)
DE (1) DE69305491T2 (es)
DK (1) DK0612310T3 (es)
ES (1) ES2095073T3 (es)
IL (1) IL106872A (es)
WO (1) WO1994005621A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5274171A (en) * 1992-01-22 1993-12-28 Givaudan-Roure Corporation Process for the palladium catalyzed coupling of a diazonium salt with an olefinic bond
IL118817A (en) * 1995-08-24 1999-06-20 Bromine Compounds Ltd Process for the preparation of octyl p-methoxy cinnamate
US5827805A (en) * 1996-02-29 1998-10-27 The Lubrizol Corporation Condensates of alkyl phenols and glyoxal and products derived therefrom
US6624197B1 (en) 1998-05-08 2003-09-23 Calyx Therapeutics, Inc. Diphenylethylene compounds
US20080108825A1 (en) * 1999-11-08 2008-05-08 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US7323496B2 (en) * 1999-11-08 2008-01-29 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US20020002200A1 (en) * 2000-02-04 2002-01-03 Bishwagit Nag Novel diphenylethylene compounds
US20080103302A1 (en) * 2000-02-04 2008-05-01 Theracos, Inc. Compounds for treatment of inflammation, diabetes and related disorders
US6413504B1 (en) * 2000-06-30 2002-07-02 Calyx Therapeutics, Inc. Alpha-arylated cinnamic esters and 1,4-bis(alpha-carboxyl-beta-styryl)benzene esters an UV-blocking agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4965361A (en) * 1989-02-27 1990-10-23 Eastman Kodak Company Preparation of 4-substituted aryl olefins
US4970332A (en) * 1989-03-09 1990-11-13 Mallinckrodt, Inc. Process for producing 2-ethylhexyl-p-methoxycinnamate
JP2803386B2 (ja) * 1991-04-16 1998-09-24 株式会社明電舎 電縫管溶接管理方法およびその装置

Also Published As

Publication number Publication date
EP0612310A1 (en) 1994-08-31
EP0612310B1 (en) 1996-10-16
AU659570B2 (en) 1995-05-18
JPH07500847A (ja) 1995-01-26
DE69305491D1 (de) 1996-11-21
JP3539730B2 (ja) 2004-07-07
ATE144242T1 (de) 1996-11-15
US5457226A (en) 1995-10-10
IL106872A (en) 1996-10-16
DK0612310T3 (da) 1997-03-24
WO1994005621A1 (en) 1994-03-17
AU4954593A (en) 1994-03-29
DE69305491T2 (de) 1997-05-15
IL106872A0 (en) 1993-12-28

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