ES2090806T3 - Acilsulfonamido- y sulfonamido-piridina-2-esteres de acidos carboxilicos, asi como sus piridina-n-oxidos, procedimientos para su preparacion y su utilizacion como medicamentos. - Google Patents

Acilsulfonamido- y sulfonamido-piridina-2-esteres de acidos carboxilicos, asi como sus piridina-n-oxidos, procedimientos para su preparacion y su utilizacion como medicamentos.

Info

Publication number
ES2090806T3
ES2090806T3 ES93115361T ES93115361T ES2090806T3 ES 2090806 T3 ES2090806 T3 ES 2090806T3 ES 93115361 T ES93115361 T ES 93115361T ES 93115361 T ES93115361 T ES 93115361T ES 2090806 T3 ES2090806 T3 ES 2090806T3
Authority
ES
Spain
Prior art keywords
piridina
acilsulfonamido
oxidos
esteres
sulfonamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93115361T
Other languages
English (en)
Inventor
Klaus Dr Weidmann
Martin Dr Bickel
Volkmar Dr Gunzler-Pukall
Karl-Heinz Dr Baringhaus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2090806T3 publication Critical patent/ES2090806T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION SE REFIERE AL ESTER DEL ACIDO ACILSULFONAMIDO DINA DE LA FORMULA GENERAL I DONDE A = R3 Y B = X -NR5R6 O B = R3 Y A = X NR5R6. LOS COMPUESTOS SON APROPIADOS COMO MEDICAMENTOS CONTRA ENFERMEDADES FIBROTICAS.
ES93115361T 1992-10-02 1993-09-23 Acilsulfonamido- y sulfonamido-piridina-2-esteres de acidos carboxilicos, asi como sus piridina-n-oxidos, procedimientos para su preparacion y su utilizacion como medicamentos. Expired - Lifetime ES2090806T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4233124A DE4233124A1 (de) 1992-10-02 1992-10-02 Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ES2090806T3 true ES2090806T3 (es) 1996-10-16

Family

ID=6469456

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93115361T Expired - Lifetime ES2090806T3 (es) 1992-10-02 1993-09-23 Acilsulfonamido- y sulfonamido-piridina-2-esteres de acidos carboxilicos, asi como sus piridina-n-oxidos, procedimientos para su preparacion y su utilizacion como medicamentos.

Country Status (25)

Country Link
US (1) US5428046A (es)
EP (1) EP0590520B1 (es)
JP (1) JPH06211795A (es)
KR (1) KR940009156A (es)
CN (1) CN1089603A (es)
AT (1) ATE139227T1 (es)
AU (1) AU662448B2 (es)
CA (1) CA2107514A1 (es)
CZ (1) CZ283869B6 (es)
DE (2) DE4233124A1 (es)
DK (1) DK0590520T3 (es)
ES (1) ES2090806T3 (es)
FI (1) FI103881B1 (es)
GR (1) GR3020230T3 (es)
HK (1) HK1006713A1 (es)
HU (1) HUT67292A (es)
IL (1) IL107155A (es)
MY (1) MY110277A (es)
NO (1) NO180085C (es)
NZ (1) NZ248819A (es)
PH (1) PH30677A (es)
PL (1) PL176772B1 (es)
RU (1) RU2117660C1 (es)
TW (1) TW258733B (es)
ZA (1) ZA937298B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL135495A (en) * 1995-09-28 2002-12-01 Hoechst Ag Intermediate compounds for the preparation of quinoline-converted amines - 2 - carboxylic acid
DE19742951A1 (de) 1997-09-29 1999-04-15 Hoechst Schering Agrevo Gmbh Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende Mittel und Verfahren zu ihrer Herstellung
DE19746287A1 (de) * 1997-10-20 1999-04-22 Hoechst Marion Roussel De Gmbh Substituierte Isochinolin-2-Carbonsäureamide, ihre Herstellung und ihre Verwendung als Arzneimittel
TW201512171A (zh) 2013-04-19 2015-04-01 Pfizer Ltd 化學化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3432094A1 (de) * 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
DE3703959A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3703963A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
DE3703962A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3707429A1 (de) * 1987-03-07 1988-09-15 Hoechst Ag Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE4020570A1 (de) * 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung
DE4031000A1 (de) * 1990-10-01 1992-04-09 Hoechst Ag 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel

Also Published As

Publication number Publication date
FI103881B (fi) 1999-10-15
FI103881B1 (fi) 1999-10-15
NO933521L (no) 1994-04-05
GR3020230T3 (en) 1996-09-30
HUT67292A (en) 1995-03-28
FI934303A0 (fi) 1993-09-30
TW258733B (es) 1995-10-01
ZA937298B (en) 1994-04-25
EP0590520A1 (de) 1994-04-06
US5428046A (en) 1995-06-27
DE59302898D1 (de) 1996-07-18
HU9302778D0 (en) 1993-12-28
AU662448B2 (en) 1995-08-31
ATE139227T1 (de) 1996-06-15
KR940009156A (ko) 1994-05-20
DK0590520T3 (da) 1996-10-14
HK1006713A1 (en) 1999-03-12
AU4872693A (en) 1994-04-14
PH30677A (en) 1997-09-16
PL300561A1 (en) 1994-04-05
CN1089603A (zh) 1994-07-20
IL107155A (en) 1999-09-22
IL107155A0 (en) 1993-12-28
JPH06211795A (ja) 1994-08-02
NO180085C (no) 1997-02-12
RU2117660C1 (ru) 1998-08-20
PL176772B1 (pl) 1999-07-30
EP0590520B1 (de) 1996-06-12
MY110277A (en) 1998-03-31
FI934303A (fi) 1994-04-03
DE4233124A1 (de) 1994-04-07
CZ204493A3 (en) 1994-05-18
NO180085B (no) 1996-11-04
CZ283869B6 (cs) 1998-06-17
CA2107514A1 (en) 1994-04-03
NZ248819A (en) 1996-02-27
NO933521D0 (no) 1993-10-01

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