ES2088925T3 - Promotores de la actividad del factor estimulador de colonias. - Google Patents
Promotores de la actividad del factor estimulador de colonias.Info
- Publication number
- ES2088925T3 ES2088925T3 ES90113097T ES90113097T ES2088925T3 ES 2088925 T3 ES2088925 T3 ES 2088925T3 ES 90113097 T ES90113097 T ES 90113097T ES 90113097 T ES90113097 T ES 90113097T ES 2088925 T3 ES2088925 T3 ES 2088925T3
- Authority
- ES
- Spain
- Prior art keywords
- promoters
- stimulating factor
- activity
- mip
- colonies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/195—Chemokines, e.g. RANTES
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/21—Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Developmental Biology & Embryology (AREA)
- Physiology (AREA)
Abstract
EL PRESENTE INVENTO SE REFIERE A LA IDENTIFICACION DE PROMOTORES DE LA PRODUCCION DE LAS CELULAS MIELOPOIETICAS DE LA ASNGRE. EN PARTICULAR, SE HA DECUBIERTO UN AGENTE QUE INCREMENTA EL FACTOR DE ACTIVACION DE LA ESTIMULACION DE LAS COLONIAS MIELOPOIETICAS. EL AGENTE COMPRENDE CITOQUINAS QUE ADEMAS SON CAPACES DE UNIRSE A LA HEPARINA, E INDUCIR LA INFLAMACION LOCAL CARACTERIZADA POR LA INFILTRACION CELULAR POLIMORFONUCLEAR CUANDO SE ADMINISTRA SUBCUTANEAMENTE. LOS AGENTES PARTICULARES COMPRENDEN LAS CITOQUINAS INFLAMATORIAS MIP-1 Y MIP-2. SE PROPONEN EMPLEOS DIAGNOSTICOS Y TERAPEUTICOS, ASI COMO COMPOSICIONES FARMACEUTICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37793789A | 1989-07-10 | 1989-07-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2088925T3 true ES2088925T3 (es) | 1996-10-01 |
Family
ID=23491090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90113097T Expired - Lifetime ES2088925T3 (es) | 1989-07-10 | 1990-07-09 | Promotores de la actividad del factor estimulador de colonias. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0409040B1 (es) |
JP (1) | JPH04501860A (es) |
AT (1) | ATE129158T1 (es) |
AU (1) | AU638473B2 (es) |
CA (1) | CA2035861A1 (es) |
DE (1) | DE69023060T2 (es) |
DK (1) | DK0409040T3 (es) |
ES (1) | ES2088925T3 (es) |
GR (1) | GR3018675T3 (es) |
IE (1) | IE72139B1 (es) |
PT (1) | PT94641A (es) |
WO (1) | WO1991000919A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5145676A (en) * | 1981-09-08 | 1992-09-08 | The Rockefeller University | Method and agents for promoting wound healing |
US5154921A (en) * | 1990-07-13 | 1992-10-13 | Dana-Farber Cancer Institute, Inc. | Promotion of maturation of hematopoietic progenitor cells |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1208546A (en) * | 1981-09-08 | 1986-07-29 | Anthony Cerami | Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay) |
JP3022566B2 (ja) * | 1987-10-02 | 2000-03-21 | ザ ロックフェラー ユニバーシティ | 大食細胞誘導炎症性神経細胞 |
WO1990002762A1 (en) * | 1988-09-02 | 1990-03-22 | The Rockefeller University | Macrophage-derived inflammatory mediator (mip-2) |
-
1990
- 1990-07-09 AT AT90113097T patent/ATE129158T1/de not_active IP Right Cessation
- 1990-07-09 IE IE248690A patent/IE72139B1/en not_active IP Right Cessation
- 1990-07-09 PT PT94641A patent/PT94641A/pt not_active Application Discontinuation
- 1990-07-09 ES ES90113097T patent/ES2088925T3/es not_active Expired - Lifetime
- 1990-07-09 DE DE69023060T patent/DE69023060T2/de not_active Expired - Fee Related
- 1990-07-09 DK DK90113097.1T patent/DK0409040T3/da active
- 1990-07-09 EP EP90113097A patent/EP0409040B1/en not_active Expired - Lifetime
- 1990-07-10 AU AU60402/90A patent/AU638473B2/en not_active Ceased
- 1990-07-10 WO PCT/US1990/003853 patent/WO1991000919A1/en active Application Filing
- 1990-07-10 JP JP2510403A patent/JPH04501860A/ja active Pending
- 1990-07-10 CA CA002035861A patent/CA2035861A1/en not_active Abandoned
-
1996
- 1996-01-16 GR GR960400074T patent/GR3018675T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU6040290A (en) | 1991-02-06 |
WO1991000919A1 (en) | 1991-01-24 |
CA2035861A1 (en) | 1991-01-11 |
EP0409040B1 (en) | 1995-10-18 |
ATE129158T1 (de) | 1995-11-15 |
EP0409040A1 (en) | 1991-01-23 |
DK0409040T3 (da) | 1995-12-27 |
IE72139B1 (en) | 1997-03-26 |
JPH04501860A (ja) | 1992-04-02 |
PT94641A (pt) | 1991-04-18 |
DE69023060T2 (de) | 1996-04-18 |
AU638473B2 (en) | 1993-07-01 |
GR3018675T3 (en) | 1996-04-30 |
DE69023060D1 (de) | 1995-11-23 |
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Legal Events
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