ES2087555T3 - Derivados de acido n-tritilo aspartico utilizados para la preparacion de antagonistas de fosfonato nmda. - Google Patents
Derivados de acido n-tritilo aspartico utilizados para la preparacion de antagonistas de fosfonato nmda.Info
- Publication number
- ES2087555T3 ES2087555T3 ES92921774T ES92921774T ES2087555T3 ES 2087555 T3 ES2087555 T3 ES 2087555T3 ES 92921774 T ES92921774 T ES 92921774T ES 92921774 T ES92921774 T ES 92921774T ES 2087555 T3 ES2087555 T3 ES 2087555T3
- Authority
- ES
- Spain
- Prior art keywords
- derivatives
- preparation
- trythyl
- phosphonate
- aspartic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Abstract
LA PRESENTE INVENCION SE REFIERE A NUEVOS DERIVADOS DE (R) FIMETIL N-TRILILASPARATO Y NUEVOS DERIVADOS DE (R)-ALQUILO N-TRILIL-4-OXO-5FOSFONONORVALINATO QUE SON UTILES EN LA PREPARACION DE LA CLASE DE ANTAGONISTAS DE NMDA BETACETOFOSFONATO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79283491A | 1991-11-15 | 1991-11-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2087555T3 true ES2087555T3 (es) | 1996-07-16 |
Family
ID=25158215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92921774T Expired - Lifetime ES2087555T3 (es) | 1991-11-15 | 1992-10-13 | Derivados de acido n-tritilo aspartico utilizados para la preparacion de antagonistas de fosfonato nmda. |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0613459B1 (es) |
JP (1) | JP3168563B2 (es) |
KR (1) | KR100241480B1 (es) |
AT (1) | ATE134989T1 (es) |
AU (1) | AU667845B2 (es) |
CA (1) | CA2121835A1 (es) |
DE (1) | DE69208888T2 (es) |
DK (1) | DK0613459T3 (es) |
ES (1) | ES2087555T3 (es) |
FI (1) | FI942248A (es) |
GR (1) | GR3019587T3 (es) |
HU (1) | HU214055B (es) |
IL (1) | IL103710A (es) |
MX (1) | MX9206448A (es) |
NO (1) | NO305314B1 (es) |
WO (1) | WO1993010075A1 (es) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2025326C (en) * | 1989-09-19 | 2001-04-24 | Jeffrey P. Whitten | Nmda antagonists |
-
1992
- 1992-10-13 DE DE69208888T patent/DE69208888T2/de not_active Expired - Fee Related
- 1992-10-13 WO PCT/US1992/008739 patent/WO1993010075A1/en active IP Right Grant
- 1992-10-13 AU AU28642/92A patent/AU667845B2/en not_active Ceased
- 1992-10-13 JP JP50924593A patent/JP3168563B2/ja not_active Expired - Fee Related
- 1992-10-13 HU HU9401469A patent/HU214055B/hu not_active IP Right Cessation
- 1992-10-13 CA CA002121835A patent/CA2121835A1/en not_active Abandoned
- 1992-10-13 AT AT92921774T patent/ATE134989T1/de not_active IP Right Cessation
- 1992-10-13 KR KR1019940701634A patent/KR100241480B1/ko not_active IP Right Cessation
- 1992-10-13 EP EP92921774A patent/EP0613459B1/en not_active Expired - Lifetime
- 1992-10-13 ES ES92921774T patent/ES2087555T3/es not_active Expired - Lifetime
- 1992-10-13 DK DK92921774.3T patent/DK0613459T3/da active
- 1992-11-10 MX MX9206448A patent/MX9206448A/es not_active IP Right Cessation
- 1992-11-11 IL IL103710A patent/IL103710A/en not_active IP Right Cessation
-
1994
- 1994-05-13 NO NO941820A patent/NO305314B1/no not_active IP Right Cessation
- 1994-05-13 FI FI942248A patent/FI942248A/fi unknown
-
1996
- 1996-04-09 GR GR960400979T patent/GR3019587T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO941820D0 (no) | 1994-05-13 |
JP3168563B2 (ja) | 2001-05-21 |
JPH07501523A (ja) | 1995-02-16 |
NO305314B1 (no) | 1999-05-10 |
HU9401469D0 (en) | 1994-08-29 |
MX9206448A (es) | 1993-05-01 |
HUT70551A (en) | 1995-10-30 |
FI942248A0 (fi) | 1994-05-13 |
IL103710A (en) | 1998-02-08 |
CA2121835A1 (en) | 1993-05-27 |
FI942248A (fi) | 1994-05-13 |
NO941820L (no) | 1994-05-13 |
EP0613459B1 (en) | 1996-03-06 |
DE69208888T2 (de) | 1996-08-01 |
DE69208888D1 (de) | 1996-04-11 |
WO1993010075A1 (en) | 1993-05-27 |
GR3019587T3 (en) | 1996-07-31 |
DK0613459T3 (da) | 1996-04-01 |
HU214055B (en) | 1997-12-29 |
ATE134989T1 (de) | 1996-03-15 |
IL103710A0 (en) | 1993-04-04 |
AU2864292A (en) | 1993-06-15 |
EP0613459A1 (en) | 1994-09-07 |
KR100241480B1 (ko) | 2000-03-02 |
AU667845B2 (en) | 1996-04-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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