ES2086334T3 - Derivados de tilosina. - Google Patents
Derivados de tilosina.Info
- Publication number
- ES2086334T3 ES2086334T3 ES90114291T ES90114291T ES2086334T3 ES 2086334 T3 ES2086334 T3 ES 2086334T3 ES 90114291 T ES90114291 T ES 90114291T ES 90114291 T ES90114291 T ES 90114291T ES 2086334 T3 ES2086334 T3 ES 2086334T3
- Authority
- ES
- Spain
- Prior art keywords
- mycarosyl
- ch2oh
- double bond
- bond
- single bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical group O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 8
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- WBPYTXDJUQJLPQ-VMXQISHHSA-N tylosin Chemical class O([C@@H]1[C@@H](C)O[C@H]([C@@H]([C@H]1N(C)C)O)O[C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@H]1C[C@@](C)(O)[C@@H](O)[C@H](C)O1 WBPYTXDJUQJLPQ-VMXQISHHSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE PRESENTAN DERIVADOS DE TILOSINA DE LAS FORMULAS DE LA FIGURA, CUYOS ELEMENTOS SE DEFINEN EN LA TABLA DE LA FIGURA; ASI MISMO SE PRESENTA UN METODO PARA LA PREPARACION DE LOS MISMOS Y SU USO EN LA OBTENCION DE PRODUCTOS FARMACEUTICOS, ESPECIALMENTE EN LA SINTESIS DE ANTIBIOTICOS DE AZALURO DE 17 MIEMBROS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU01498/89A YU149889A (en) | 1989-07-26 | 1989-07-26 | Process for preparing biologically active derivatives of tylozine |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2086334T3 true ES2086334T3 (es) | 1996-07-01 |
Family
ID=25554392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90114291T Expired - Lifetime ES2086334T3 (es) | 1989-07-26 | 1990-07-25 | Derivados de tilosina. |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0410433B1 (es) |
AT (1) | ATE134642T1 (es) |
DE (1) | DE69025505T2 (es) |
ES (1) | ES2086334T3 (es) |
SI (1) | SI8911498B (es) |
YU (1) | YU149889A (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI9012363A (sl) * | 1990-12-14 | 1998-04-30 | Pliva | Derivati 10,11,12,13-tetrahidro-desmikozina, postopki za njihovo pripravo in postopki za pripravo farmacevtskih preparatov |
CA2064634C (en) * | 1991-04-04 | 1998-08-04 | James V. Heck | 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions |
CA2065222A1 (en) * | 1991-04-09 | 1992-10-10 | Robert R. Wilkening | Process for the preparation of 8a-aza-8a-homoerythromycin cyclic iminoethers |
EP0515141A1 (en) * | 1991-05-20 | 1992-11-25 | Merck & Co. Inc. | Novel process for the preparation of 8A-aza-8A-homoerythromycin cyclic lactams |
EP0747401B1 (en) * | 1995-06-06 | 2001-10-17 | Fina Technology, Inc. | Bifunctional electron donors for olefin polymerization |
CZ211798A3 (cs) * | 1997-07-16 | 1999-02-17 | Pliva, Farmaceutska, Kemijska, Prehrambena I Kozmetička Industrije, Dioničko Društvo | Lineární 8a-sekoazalidy a způsob jejich výroby |
HRP990192A2 (en) * | 1999-06-11 | 2001-04-30 | Pliva D D | 4'-DEMICAROZYL-8a-AZA-8a-HOMOTHILOSINE DERIVATIVES |
US7365174B2 (en) | 2003-08-22 | 2008-04-29 | Meiji Seika Kaisha, Ltd. | Azalide and azalactam derivatives and method for producing the same |
US7247617B2 (en) * | 2004-07-13 | 2007-07-24 | Kosan Biosciences Incorporated | Sixteen-member macrolide antiinfective agents |
GB201608236D0 (en) * | 2016-05-11 | 2016-06-22 | Fidelta D O O | Seco macrolide compounds |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3178341A (en) * | 1960-06-27 | 1965-04-13 | Lilly Co Eli | Antibiotics tylosin and desmycosin and derivatives thereof |
PH19293A (en) * | 1982-11-15 | 1986-03-04 | Pfizer | Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof |
YU45033B (en) * | 1987-04-14 | 1991-06-30 | Pliva Zagreb | Process for preparing 10,11,12,13-tetrahydro derivative |
-
1989
- 1989-07-26 SI SI8911498A patent/SI8911498B/sl unknown
- 1989-07-26 YU YU01498/89A patent/YU149889A/xx unknown
-
1990
- 1990-07-25 ES ES90114291T patent/ES2086334T3/es not_active Expired - Lifetime
- 1990-07-25 AT AT90114291T patent/ATE134642T1/de not_active IP Right Cessation
- 1990-07-25 EP EP90114291A patent/EP0410433B1/en not_active Expired - Lifetime
- 1990-07-25 DE DE69025505T patent/DE69025505T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0410433B1 (en) | 1996-02-28 |
DE69025505D1 (de) | 1996-04-04 |
SI8911498B (sl) | 1998-10-31 |
EP0410433A3 (en) | 1991-11-06 |
SI8911498A (sl) | 1998-02-28 |
YU149889A (en) | 1991-02-28 |
EP0410433A2 (en) | 1991-01-30 |
DE69025505T2 (de) | 1996-09-19 |
ATE134642T1 (de) | 1996-03-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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