FI891449A - Nya 2,3,4-substituerade imidazoler och 3,4,5-substituerade 1,2,4-triazoler, deras framstaellning och anvaendning. - Google Patents

Nya 2,3,4-substituerade imidazoler och 3,4,5-substituerade 1,2,4-triazoler, deras framstaellning och anvaendning. Download PDF

Info

Publication number
FI891449A
FI891449A FI891449A FI891449A FI891449A FI 891449 A FI891449 A FI 891449A FI 891449 A FI891449 A FI 891449A FI 891449 A FI891449 A FI 891449A FI 891449 A FI891449 A FI 891449A
Authority
FI
Finland
Prior art keywords
substituerade
och
triazoler
imidazoler
nya
Prior art date
Application number
FI891449A
Other languages
English (en)
Other versions
FI891449A0 (fi
Inventor
Kurt Schromm
Anton Mentrup
Ernst-Otto Renth
Hubert Heuer
Gojko Muacevic
Franz Birke
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI891449A0 publication Critical patent/FI891449A0/fi
Publication of FI891449A publication Critical patent/FI891449A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI891449A 1988-03-30 1989-03-28 Nya 2,3,4-substituerade imidazoler och 3,4,5-substituerade 1,2,4-triazoler, deras framstaellning och anvaendning. FI891449A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3810848A DE3810848A1 (de) 1988-03-30 1988-03-30 Neue 2,3,4-substituierte imidazole und 3,4,5-substituierte 1,2,4-triazole, ihre herstellung und verwendung

Publications (2)

Publication Number Publication Date
FI891449A0 FI891449A0 (fi) 1989-03-28
FI891449A true FI891449A (fi) 1989-10-01

Family

ID=6351100

Family Applications (1)

Application Number Title Priority Date Filing Date
FI891449A FI891449A (fi) 1988-03-30 1989-03-28 Nya 2,3,4-substituerade imidazoler och 3,4,5-substituerade 1,2,4-triazoler, deras framstaellning och anvaendning.

Country Status (18)

Country Link
EP (1) EP0335381A1 (fi)
JP (1) JPH02503679A (fi)
KR (1) KR900700459A (fi)
AU (1) AU3228689A (fi)
DD (1) DD283620A5 (fi)
DE (2) DE3810848A1 (fi)
DK (1) DK151489A (fi)
FI (1) FI891449A (fi)
FR (1) FR2629457A1 (fi)
GB (1) GB2216890A (fi)
HU (1) HUT52091A (fi)
IL (1) IL89788A0 (fi)
NO (1) NO891293L (fi)
PL (1) PL278547A1 (fi)
PT (1) PT90142A (fi)
WO (1) WO1989009212A1 (fi)
YU (1) YU65489A (fi)
ZA (1) ZA892259B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3927483A1 (de) * 1989-08-19 1991-02-21 Boehringer Ingelheim Kg Neue substituierte heterocyclische fuenfringe, ihre herstellung und verwendung
US5120749A (en) * 1991-02-20 1992-06-09 Abbott Laboratories Platelet activating antagonists
US5155117A (en) * 1991-04-12 1992-10-13 G. D. Searle & Co. 1-arylheteroarylalkyl substituted-1h-1,2,4-triazole compounds for treatment of circulatory disorders
DE69232003T2 (de) * 1991-09-18 2002-04-25 Glaxo Group Ltd Benzanilidderivate als 5-HT1D-Antagonisten
AU2003251739A1 (en) 2002-07-02 2004-01-23 Schering Corporation New neuropeptide y y5 receptor antagonists
DE60227008D1 (de) * 2002-07-04 2008-07-17 Aventis Pharma Sa Neue thiophenacylhydrazinoderivate, verfahren zu deren herstellung, deren verwendung als arzneimittel, pharmazeutische zusammensetzungen und neue anwendungen
US20040192728A1 (en) 2003-02-03 2004-09-30 Ellen Codd Quinoline-derived amide modulators of vanilloid VR1 receptor
PL1858877T3 (pl) 2005-01-14 2014-08-29 Gilead Connecticut Inc 1,3 podstawione diarylem moczniki jako modulatory aktywności kinazy
US7777040B2 (en) 2005-05-03 2010-08-17 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
UY30892A1 (es) 2007-02-07 2008-09-02 Smithkline Beckman Corp Inhibidores de la actividad akt
UA106740C2 (uk) 2009-01-30 2014-10-10 Глаксосмітклайн Ллс Кристалічний гідрохлорид n-{(1s)-2-аміно-1-[(3-фторфеніл)метил]етил}-5-хлор-4-(4-хлор-1-метил-1h-піразол-5-іл)-2-тіофенкарбоксаміду
KR101735675B1 (ko) 2009-12-11 2017-05-15 오티포니 세라피틱스 리미티드 이미다졸리딘디온 유도체
WO2012076877A1 (en) 2010-12-06 2012-06-14 Autifony Therapeutics Limited Hydantoin derivatives useful as kv3 inhibitors
US9193704B2 (en) 2011-06-07 2015-11-24 Autifony Therapeutics Limited Hydantoin derivatives as KV3 inhibitors
JP6240667B2 (ja) 2012-05-22 2017-11-29 アウトイフオンイ トヘラペウトイクス リミテッド Kv3阻害剤としてのトリアゾール
US9669030B2 (en) 2012-05-22 2017-06-06 Autifony Therapeutics Limited Hydantoin derivatives as Kv3 inhibitors
EP4085056A1 (en) 2020-01-03 2022-11-09 Berg LLC Polycyclic amides as ube2k modulators for treating cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3842089A (en) * 1971-08-18 1974-10-15 Upjohn Co 4-(alpha-(phenyl)-o-toly)-4h-1,2,4-triazoles
GB1378617A (en) * 1972-05-05 1974-12-27 Upjohn Co Triazolylbenzophenones
FR2269938A2 (en) * 1974-05-08 1975-12-05 Delalande Sa 5-Hydroxymethyl-3,4-diphenyl-1,2,4-triazoles - with anticholinergic, bronchodilator, antidepressant, analgesic, vasodilator activity, etc.
FR2539127B1 (fr) * 1983-01-10 1985-08-23 Roussel Uclaf Nouveaux derives du 4h-1,2,4-triazole, leur procede de preparation et leur application comme medicaments
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
SU1681729A3 (ru) * 1986-07-25 1991-09-30 Берингер Ингельгейм Кг (Фирма) Способ получени производных 1,4-бензодиазепина
FR2813807B1 (fr) * 2000-09-14 2002-11-15 Filtrauto Filtre a gazole incluant un circuit electrique et dispositif de filtration comportant un tel filtre

Also Published As

Publication number Publication date
DE3990284D2 (en) 1990-04-05
NO891293D0 (no) 1989-03-28
HUT52091A (en) 1990-06-28
IL89788A0 (en) 1989-09-28
PT90142A (pt) 1989-11-10
FR2629457A1 (fr) 1989-10-06
FI891449A0 (fi) 1989-03-28
ZA892259B (en) 1990-12-28
DK151489A (da) 1989-10-01
DE3810848A1 (de) 1989-10-19
YU65489A (en) 1991-04-30
WO1989009212A1 (en) 1989-10-05
EP0335381A1 (de) 1989-10-04
AU3228689A (en) 1989-10-05
KR900700459A (ko) 1990-08-13
PL278547A1 (en) 1990-01-08
NO891293L (no) 1989-10-02
GB2216890A (en) 1989-10-18
JPH02503679A (ja) 1990-11-01
DK151489D0 (da) 1989-03-29
DD283620A5 (de) 1990-10-17
GB8907042D0 (en) 1989-05-10

Similar Documents

Publication Publication Date Title
FI906468A0 (fi) Nya viskositetsindexfoerhoejande kompositioner och newtonsk smoerjmedelsblandning.
FI905109A0 (fi) Nya hyaluronsyrasammansaettningar innehaollande kompositioner och foerfarande foer deras framstaellning.
FI902734A0 (fi) Nya 2-hydroxi-n-propylaminer, dessa foereningar innehaollande laekemedel och foerfarande foer deras framstaellning.
FI891167A0 (fi) Nya ympade sulfonerade polyestrar foerfarande foer framstaellning av dessa och deras anvaendning foer klistring av textiltraodar och -fiber.
FI891449A0 (fi) Nya 2,3,4-substituerade imidazoler och 3,4,5-substituerade 1,2,4-triazoler, deras framstaellning och anvaendning.
FI892506A0 (fi) Nya mellanprodukter och foerfarande foer framstaellning av organiska syror.
FI883347A0 (fi) Nya 5-aminometylen-2,4 -imidazolidindioner och 5-aminometylen-4-tionoimidazolidin-4-oner.
FI894629A (fi) Nya 3,4-diaminokinolin- och -pyridinfoereningar.
FI894798A0 (fi) Nya 1,4-bensoxazin- och 1,4-bensotiazinderivat och foerfarande foer deras framstaellning.
FI904533A0 (fi) Nya tiazolderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandingar.
FI873243A0 (fi) Nya 1,4-benzodiazepiner, deras framstaellning och anvaendning.
FI860556A (fi) Nya 1,8-naftyridinderivat och foerfarande foer deras framstaellning.
FI893142A0 (fi) Nya aromoljor av minttyp, foerfarande foer framstaellning av desamma, och kompositioner innehaollande desamma.
FI890285A (fi) Nya aminosyraglycerider, foerfaranden foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning.
FI885056A (fi) Nya fluormetoxifenyldihydropyridiner, foerfarande foer deras framstaellning och deras anvaendning i laekemedel.
FI891153A0 (fi) Nya 3,4,5-substituerade 4h-1,2,4-triazoler, deras framstaellning och anvaendning.
FI885722A0 (fi) Nya kinolinderivat, foerfaranden foer framstaellning daerav och antibakteriella aemnen innehaollande desamma.
FI884225A0 (fi) Nya aminosyraestrar, foerfaranden foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning.
FI881899A (fi) Nya 2 ,16 -diaminoandrostaner.
FI890846A0 (fi) Nya tiorodaminer och nytt foerfarande foer deras framstaellning.
FI891308A (fi) Nya polypeptider med tillvaextfaktoraktivitet och dessa kodande nukleinsyrasekvenser.
FI890380A0 (fi) Nya kondenserande diazepinoner, foerfarande foer deras framstaellning och dessa foereningar innehaollande laekemedel.
FI911403A0 (fi) Nya kinolinderivat och foerfarande foer deras framstaellning.
FI902111A0 (fi) Substituerade bifenylkolsyror, foerfarande foer deras framstaellning och nya mellanprodukter.
FI885057A (fi) Nya fluormetoxifenyldihydropyridiner, foerfaranden foer deras framstaellning och deras anvaendning i laekemedel.

Legal Events

Date Code Title Description
FD Application lapsed

Owner name: BOEHRINGER INGELHEIM KG