ES2086268T1 - Drogas para aplicacion topica de esteroides sexuados en el tratamiento del sindrome del ojo seco, y metodos de preparacion y aplicacion. - Google Patents

Drogas para aplicacion topica de esteroides sexuados en el tratamiento del sindrome del ojo seco, y metodos de preparacion y aplicacion.

Info

Publication number
ES2086268T1
ES2086268T1 ES91917537T ES91917537T ES2086268T1 ES 2086268 T1 ES2086268 T1 ES 2086268T1 ES 91917537 T ES91917537 T ES 91917537T ES 91917537 T ES91917537 T ES 91917537T ES 2086268 T1 ES2086268 T1 ES 2086268T1
Authority
ES
Spain
Prior art keywords
application
preparation
dry eye
eye syndrome
drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES91917537T
Other languages
English (en)
Other versions
ES2086268T3 (es
Inventor
Virginia Lubkin
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Individual
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES2086268T1 publication Critical patent/ES2086268T1/es
Application granted granted Critical
Publication of ES2086268T3 publication Critical patent/ES2086268T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UNA APLICACION DE FARMACOS TOPICOS PARA ALIVIAR LA QUERATOCONJUNTIVITIS SECA (SINDROME DE SEQUEDAD EN LOS OJOS) QUE COMPRENDE UNA SOLUCION DE ESTEROIDES SEXUALES O SUS DERIVADOS SUSPENDIDOS O DISUELTOS EN UN VEHICULO, Y EL METODO DE PREPARACION Y APLICACION DE LA MISMA. EN LOS ASPECTOS PREFERENTES DE LA INVENCION, EL ESTEROIDE SEXUAL CONSISTE ESENCIALMENTE EN ESTROGENO CONJUGADO EN UN VEHICULO LIPIDO O UN DERIVADO DEL ESTROGENO CONOCIDO COMO DISODIO 3-FOSFATO DE 17 BETA-ESTRADIOL DISUELTO EN UN VEHICULO ACUOSO QUE TIENE UN PH ENTRE 6 Y 8.
ES91917537T 1991-08-17 1991-08-17 Farmacos para la aplicacion topica de esteroides sexuales en el tratamiento del sindrome del ojo seco y procedimientos de preparacion y aplicacion. Expired - Lifetime ES2086268T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1991/005863 WO1993003731A1 (en) 1991-08-17 1991-08-17 Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application

Publications (2)

Publication Number Publication Date
ES2086268T1 true ES2086268T1 (es) 1996-07-01
ES2086268T3 ES2086268T3 (es) 2003-11-16

Family

ID=22225745

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91917537T Expired - Lifetime ES2086268T3 (es) 1991-08-17 1991-08-17 Farmacos para la aplicacion topica de esteroides sexuales en el tratamiento del sindrome del ojo seco y procedimientos de preparacion y aplicacion.

Country Status (8)

Country Link
US (1) US5041434A (es)
EP (1) EP0652754B1 (es)
AT (1) ATE234100T1 (es)
DE (2) DE69133214T2 (es)
DK (1) DK0652754T3 (es)
ES (1) ES2086268T3 (es)
GR (1) GR960300027T1 (es)
WO (1) WO1993003731A1 (es)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
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Also Published As

Publication number Publication date
EP0652754A4 (en) 1994-11-09
DK0652754T3 (da) 2003-06-10
DE69133214T2 (de) 2003-12-18
GR960300027T1 (en) 1996-05-31
EP0652754A1 (en) 1995-05-17
DE652754T1 (de) 1996-09-12
ATE234100T1 (de) 2003-03-15
DE69133214D1 (de) 2003-04-17
WO1993003731A1 (en) 1993-03-04
EP0652754B1 (en) 2003-03-12
ES2086268T3 (es) 2003-11-16
US5041434A (en) 1991-08-20

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