ES2085868T3 - Detector y localizador de las emisiones de radiacion de baja energia. - Google Patents

Detector y localizador de las emisiones de radiacion de baja energia.

Info

Publication number
ES2085868T3
ES2085868T3 ES89630158T ES89630158T ES2085868T3 ES 2085868 T3 ES2085868 T3 ES 2085868T3 ES 89630158 T ES89630158 T ES 89630158T ES 89630158 T ES89630158 T ES 89630158T ES 2085868 T3 ES2085868 T3 ES 2085868T3
Authority
ES
Spain
Prior art keywords
crystal
assemblage
probe
detector
biasing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89630158T
Other languages
English (en)
Inventor
Dennis Joseph Denen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Navidea Biopharmaceuticals Inc
Original Assignee
Neoprobe Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neoprobe Corp filed Critical Neoprobe Corp
Application granted granted Critical
Publication of ES2085868T3 publication Critical patent/ES2085868T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16—Measuring radiation intensity
    • G01T1/161—Applications in the field of nuclear medicine, e.g. in vivo counting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/42—Arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A61B6/4258—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector for detecting non x-ray radiation, e.g. gamma radiation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Measurement Of Radiation (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Light Receiving Elements (AREA)
  • Nuclear Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

UN DETECTOR PARTICULARMENTE CONVENIENTE PARA SER UTILIZADO EN CIRUGIA INMUNOGUIADA CAPAZ DE DETECTAR EMISIONES GAMA MUY TENUES Y LOCALIZAR DE ESTA MANERA TUMORES CANCERIGENOS. EL DETECTOR UTILIZA UNA PROBETA MANUALMENTE OPERABLE DENTRO DE LA QUE SE CONTIENE UN CRISTAL (114) TAL COMO TELURO DE CADMIO QUE SE ASEGURA DENTRO DE UN MEDIO A PRUEBA DE LUZ. UNA ESTRUCTURA INMUNE AL RUIDO DE LA COMBINACION DE CRISTAL Y PROBETA INCLUYE LA UTILIZACION DE UNA CAPA ELECTRICAMENTE CONDUCTORA, CAPAZ DE SATISFACER UN EFECTO DE ALMOHADILLA, (92) UBICADA EN UNA CARA DEL CRISTAL (114) CONJUNTAMENTE CON CONTACTOS DE MASA Y DE POLARIZACION QUE HACEN TOPE (100, 112). UN RETENEDOR ELASTICO DE NYLON (136) SE POSICIONA EN TENSION SOBRE EL CONJUNTO DE CRISTAL (114), LOS CONTACTOS DE POLARIZACION Y MASA (112, 122-125,100) Y CAPAS ELASTICAS (92,120) PARA LOGRAR UN ENSAMBLAJE DE RETENCION POR COMPRESION. SE DESARROLLA UN ESPACIO DE AIRE INERTE (150) ENTRE LA VENTANA QUE ENFRENTA LA PARTE ANTERIOR (18) DE LA PROBETA YEL ENSAMBLAJE DE RETENCION DEL CRISTAL.
ES89630158T 1988-11-14 1989-09-21 Detector y localizador de las emisiones de radiacion de baja energia. Expired - Lifetime ES2085868T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27102388A 1988-11-14 1988-11-14
US07/404,403 US5070878A (en) 1988-11-14 1989-09-08 Detector and localizer for low energy radiation emissions

Publications (1)

Publication Number Publication Date
ES2085868T3 true ES2085868T3 (es) 1996-06-16

Family

ID=26954643

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89630158T Expired - Lifetime ES2085868T3 (es) 1988-11-14 1989-09-21 Detector y localizador de las emisiones de radiacion de baja energia.

Country Status (11)

Country Link
US (1) US5070878A (es)
EP (1) EP0371903B1 (es)
JP (1) JPH0833448B2 (es)
KR (1) KR970010363B1 (es)
AT (1) ATE136656T1 (es)
AU (1) AU618403B2 (es)
CA (1) CA1315424C (es)
DE (1) DE68926217T2 (es)
ES (1) ES2085868T3 (es)
GR (1) GR3019697T3 (es)
IL (1) IL91830A (es)

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ATE168474T1 (de) * 1992-03-04 1998-08-15 De Beers Ind Diamond Diamant-strahlungsdetektor
US5429133A (en) * 1992-12-18 1995-07-04 Neoprobe Corporation Radiation responsive laparoscopic instrument
US5441050A (en) * 1992-12-18 1995-08-15 Neoprobe Corporation Radiation responsive surgical instrument
US5427766A (en) * 1993-11-15 1995-06-27 The Dow Chemical Company Radiolabeled steroids for use in radiochemical-guided surgery
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
US5732704A (en) * 1995-10-13 1998-03-31 Neoprobe Corporation Radiation based method locating and differentiating sentinel nodes
US5857463A (en) * 1995-10-13 1999-01-12 Neoprobe Corporation Remotely controlled apparatus and system for tracking and locating a source of photoemissions
ATE322697T1 (de) * 1996-05-07 2006-04-15 Univ Michigan Festkörper-chirugie-instrument für betastrahlung
US5744805A (en) * 1996-05-07 1998-04-28 University Of Michigan Solid state beta-sensitive surgical probe
US6076009A (en) * 1997-05-05 2000-06-13 The University Of Michigan Solid state beta-sensitive surgical probe
US5682888A (en) * 1996-06-13 1997-11-04 Neoprobe Corporation Apparatus and system for detecting and locating photon emissions with remote switch control
US5810806A (en) * 1996-08-29 1998-09-22 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
GB2328014B (en) * 1997-08-11 2001-12-05 Siemens Plc Improvements in or relating to personal radiation dosemeters
US5916167A (en) * 1997-10-10 1999-06-29 Neoprobe Corporation Surgical probe apparatus and system
US6263232B1 (en) 1998-04-07 2001-07-17 University Of South Florida Method and kit for locating hyperactive parathyroid tissue or adenomatious tissue in a patient and for removal of such tissue
US6218669B1 (en) 1998-10-06 2001-04-17 Neoprobe Corporation Surgical probe apparatus
US6191422B1 (en) 1998-10-06 2001-02-20 Neoprobe Corporation Radiation probe with compound semiconductor crystal performing in a trapping-dependent operational mode
US6204505B1 (en) 1998-10-06 2001-03-20 Neoprobe Corporation Surgical probe apparatus and system
US6222193B1 (en) 1998-10-06 2001-04-24 Neoprobe Corporation Radiation responsive surgical probe apparatus
US6259095B1 (en) 1998-10-23 2001-07-10 Neoprobe Corporation System and apparatus for detecting and locating sources of radiation
US6144876A (en) * 1998-10-23 2000-11-07 Neoprobe Corporation Scanning a radiation source with a count rate output derived with a dynamic window analysis
USD424199S (en) * 1998-10-23 2000-05-02 United States Surgical Corporation Housing assembly for radiation detection
US6272373B1 (en) 1998-10-23 2001-08-07 Neoprobe Corporation Scanning system and method for locating sources of radiation emission
US6242741B1 (en) 1998-10-23 2001-06-05 United States Surgical Corporation Radiation detection apparatus
US6331703B1 (en) 1999-03-12 2001-12-18 Ethicon Endo-Surgery, Inc. Guidance method for radiation detection
US6280398B1 (en) * 1999-10-18 2001-08-28 Ethicon Endo-Surgery Methods and devices for collection of soft tissue
US6362472B1 (en) 1999-10-22 2002-03-26 Ethicon Endo-Surgery, Inc. Method for calibrating a radiation detection system
WO2004042546A1 (en) 2002-11-04 2004-05-21 V-Target Technologies Ltd. Apparatus and methods for imaging and attenuation correction
US8909325B2 (en) 2000-08-21 2014-12-09 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US8489176B1 (en) 2000-08-21 2013-07-16 Spectrum Dynamics Llc Radioactive emission detector equipped with a position tracking system and utilization thereof with medical systems and in medical procedures
US8565860B2 (en) 2000-08-21 2013-10-22 Biosensors International Group, Ltd. Radioactive emission detector equipped with a position tracking system
US8036731B2 (en) 2001-01-22 2011-10-11 Spectrum Dynamics Llc Ingestible pill for diagnosing a gastrointestinal tract
IL157007A0 (en) 2001-01-22 2004-02-08 Target Technologies Ltd V Ingestible device
US9040016B2 (en) 2004-01-13 2015-05-26 Biosensors International Group, Ltd. Diagnostic kit and methods for radioimaging myocardial perfusion
US7968851B2 (en) 2004-01-13 2011-06-28 Spectrum Dynamics Llc Dynamic spect camera
WO2006075333A2 (en) 2005-01-13 2006-07-20 Spectrum Dynamics Llc Multi-dimensional image reconstruction and analysis for expert-system diagnosis
US8571881B2 (en) 2004-11-09 2013-10-29 Spectrum Dynamics, Llc Radiopharmaceutical dispensing, administration, and imaging
US8586932B2 (en) 2004-11-09 2013-11-19 Spectrum Dynamics Llc System and method for radioactive emission measurement
US9470801B2 (en) 2004-01-13 2016-10-18 Spectrum Dynamics Llc Gating with anatomically varying durations
CN1981210A (zh) 2004-01-13 2007-06-13 光谱动力学有限责任公司 多维图像重构
US7154098B2 (en) * 2004-02-19 2006-12-26 General Electric Company Ruggedized scintillation detector for portal monitors and light pipe incorporated therein
WO2005112895A2 (en) * 2004-05-20 2005-12-01 Spectrum Dynamics Llc Ingestible device platform for the colon
EP1766550A2 (en) 2004-06-01 2007-03-28 Spectrum Dynamics LLC Methods of view selection for radioactive emission measurements
EP1778957A4 (en) 2004-06-01 2015-12-23 Biosensors Int Group Ltd OPTIMIZING THE MEASUREMENT OF RADIOACTIVE EMISSIONS IN SPECIFIC BODY STRUCTURES
US8000773B2 (en) 2004-11-09 2011-08-16 Spectrum Dynamics Llc Radioimaging
EP1827505A4 (en) 2004-11-09 2017-07-12 Biosensors International Group, Ltd. Radioimaging
US9316743B2 (en) 2004-11-09 2016-04-19 Biosensors International Group, Ltd. System and method for radioactive emission measurement
US8615405B2 (en) 2004-11-09 2013-12-24 Biosensors International Group, Ltd. Imaging system customization using data from radiopharmaceutical-associated data carrier
US9943274B2 (en) 2004-11-09 2018-04-17 Spectrum Dynamics Medical Limited Radioimaging using low dose isotope
WO2008059489A2 (en) 2006-11-13 2008-05-22 Spectrum Dynamics Llc Radioimaging applications of and novel formulations of teboroxime
EP1908011B1 (en) 2005-07-19 2013-09-04 Spectrum Dynamics LLC Reconstruction stabilizer and active vision
US8837793B2 (en) 2005-07-19 2014-09-16 Biosensors International Group, Ltd. Reconstruction stabilizer and active vision
US8644910B2 (en) 2005-07-19 2014-02-04 Biosensors International Group, Ltd. Imaging protocols
EP1952180B1 (en) 2005-11-09 2017-01-04 Biosensors International Group, Ltd. Dynamic spect camera
WO2007074466A2 (en) 2005-12-28 2007-07-05 Starhome Gmbh Late forwarding to local voicemail system of calls to roaming users
US8894974B2 (en) 2006-05-11 2014-11-25 Spectrum Dynamics Llc Radiopharmaceuticals for diagnosis and therapy
WO2008075362A2 (en) 2006-12-20 2008-06-26 Spectrum Dynamics Llc A method, a system, and an apparatus for using and processing multidimensional data
US8521253B2 (en) 2007-10-29 2013-08-27 Spectrum Dynamics Llc Prostate imaging
US8344331B1 (en) 2009-03-20 2013-01-01 Devicor Medical Products, Inc. K-alpha probe for detection of photon emissions
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IT202000007978A1 (it) * 2020-04-15 2021-10-15 Consiglio Nazionale Ricerche Rilevatore gamma direzionale

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US3646407A (en) * 1970-09-21 1972-02-29 Philips Corp Radiation detector having a semiconductor crystal
US3999071A (en) * 1975-08-26 1976-12-21 Etat Francais Nuclear detectors sensitive to alpha, beta, and gamma rays and to thermal neutrons and to methods of treatment of crystals of such detectors
US4092980A (en) * 1976-01-12 1978-06-06 G. D. Searle & Co. Fibrinogen monitor
US4461952A (en) * 1980-10-24 1984-07-24 Commissariat A L'energie Atomique Portable computing device for measuring radiations
GB2117900A (en) * 1982-03-25 1983-10-19 Michael Anthony Newell Radiation detector
US4682895A (en) * 1985-08-06 1987-07-28 Texas A&M University Fiber optic probe for quantification of colorimetric reactions
US4801803A (en) * 1987-03-17 1989-01-31 Neoprobe Corporation Detector and localizer for low energy radiation emissions
US4893013A (en) * 1987-03-17 1990-01-09 Neoprobe Corporation Detector and localizer for low energy radiation emissions

Also Published As

Publication number Publication date
GR3019697T3 (en) 1996-07-31
IL91830A0 (en) 1990-06-10
EP0371903B1 (en) 1996-04-10
CA1315424C (en) 1993-03-30
DE68926217D1 (de) 1996-05-15
US5070878A (en) 1991-12-10
AU4159889A (en) 1990-05-17
KR910006739A (ko) 1991-04-29
IL91830A (en) 1993-06-10
AU618403B2 (en) 1991-12-19
DE68926217T2 (de) 1996-11-28
EP0371903A1 (en) 1990-06-06
KR970010363B1 (ko) 1997-06-25
JPH0833448B2 (ja) 1996-03-29
JPH0483191A (ja) 1992-03-17
ATE136656T1 (de) 1996-04-15

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