ES2075219T3 - Metodos y composiciones para curar ulceras. - Google Patents
Metodos y composiciones para curar ulceras.Info
- Publication number
- ES2075219T3 ES2075219T3 ES90914339T ES90914339T ES2075219T3 ES 2075219 T3 ES2075219 T3 ES 2075219T3 ES 90914339 T ES90914339 T ES 90914339T ES 90914339 T ES90914339 T ES 90914339T ES 2075219 T3 ES2075219 T3 ES 2075219T3
- Authority
- ES
- Spain
- Prior art keywords
- histidyl
- warm
- stomach
- blooded animals
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
SE PRESENTAN UNA VARIEDAD DE COMPOSICIONES ADECUADAS PARA UTILIZARLAS CON METODOS PARA (A) REDUCIR LA FORMACION DE ULCERAS ESTOMACALES EN ANIMALES DE SANGRE CALIENTE, (B) REDUCIR LA SECRECION DE ACIDO ESTOMACAL EN ANIMALES DE SANGRE CALIENTE, (C) AUMENTAR LA SECRECION DE LA MUCOSA CITOPROTECTORA EN EL ESTOMAGO EN ANIMALES DE SANGRE CALIENTE Y (D) CICATRIZAR ULCERAS INTESTINALES O ESTOMACALES ESTABLECIDAS EN ANIMALES DE SANGRE CALIENTE. LAS COMPOSICIONES INCLUYEN GLICIL-L-HISTIDIL-L-LISINA, LLISIL-L-HISTIDIL-GLICINA, L-LISIL-L-HISTIDIL-GLICINA: COBRE (II), GLICIL-LHISTIDIL-L-LISINA: COBRE (2) Y DERIVADOS DE LAS MISMAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/401,312 US5023237A (en) | 1989-08-30 | 1989-08-30 | Methods and compositions for healing ulcers |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2075219T3 true ES2075219T3 (es) | 1995-10-01 |
Family
ID=23587222
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90914339T Expired - Lifetime ES2075219T3 (es) | 1989-08-30 | 1990-08-28 | Metodos y composiciones para curar ulceras. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5023237A (es) |
EP (1) | EP0489860B1 (es) |
JP (1) | JPH05500221A (es) |
KR (1) | KR920703627A (es) |
AT (1) | ATE125820T1 (es) |
AU (1) | AU648517B2 (es) |
CA (1) | CA2065416A1 (es) |
DE (1) | DE69021386T2 (es) |
DK (1) | DK0489860T3 (es) |
ES (1) | ES2075219T3 (es) |
WO (1) | WO1991003488A1 (es) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5120831A (en) * | 1985-02-08 | 1992-06-09 | Procyte Corporation | Metal-peptide compositions |
US5102990A (en) * | 1989-08-09 | 1992-04-07 | Rhomed Incorporated | Direct radiolabeling of antibodies and other proteins with technetium or rhenium |
US5443816A (en) * | 1990-08-08 | 1995-08-22 | Rhomed Incorporated | Peptide-metal ion pharmaceutical preparation and method |
US5145838A (en) * | 1989-08-30 | 1992-09-08 | Procyte Corporation | Methods and compositions for healing ulcers |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5643549A (en) * | 1992-02-20 | 1997-07-01 | Rhomed Incorporated | Leukostimulatory agent for in vivo leukocyte tagging |
US5382431A (en) * | 1992-09-29 | 1995-01-17 | Skin Biology, Inc. | Tissue protective and regenerative compositions |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
ATE406909T1 (de) * | 1993-05-13 | 2008-09-15 | Poniard Pharmaceuticals Inc | Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind |
WO1995026192A1 (en) * | 1994-03-28 | 1995-10-05 | Skin Biology, Inc. | Starch-metal complexes for skin and hair |
JPH07316192A (ja) * | 1994-05-27 | 1995-12-05 | Hoechst Japan Ltd | L−リシル−グリシル−l−ヒスチジンおよびこれを含有する創傷治療剤 |
US5891418A (en) * | 1995-06-07 | 1999-04-06 | Rhomed Incorporated | Peptide-metal ion pharmaceutical constructs and applications |
US6331285B1 (en) | 1996-06-05 | 2001-12-18 | Palatin Technologies, Inc. | Structurally determined cyclic metallo-constructs and applications |
US5888522A (en) * | 1996-08-23 | 1999-03-30 | Skin Biology, Inc. | Tissue protective and regenerative compositions |
US5698184A (en) * | 1996-08-23 | 1997-12-16 | Skin Biology, Inc. | Compositions and methods for skin tanning and protection |
US6117911A (en) * | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
US20030158111A1 (en) * | 1999-10-01 | 2003-08-21 | David Bar-Or | Methods and products for oral care |
KR20110049875A (ko) | 1999-10-01 | 2011-05-12 | 디엠아이 바이오사이언시스, 인크 | 금속 결합 화합물 및 그의 용도 |
US20030130185A1 (en) * | 2000-09-29 | 2003-07-10 | David Bar-Or | Metal-binding compounds and uses therefor |
US7592304B2 (en) | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
US7632803B2 (en) * | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
US7385025B2 (en) | 2000-12-19 | 2008-06-10 | Palatin Technologies, Inc. | Metallopeptide compounds |
WO2003030926A1 (en) * | 2001-10-05 | 2003-04-17 | Procyte Corporation | Stable solutions of peptide copper complexes and cosmetic and pharmaceutical formulations produced therefrom |
JP2006504448A (ja) * | 2002-07-02 | 2006-02-09 | プロサイト コーポレイション | ペプチド銅錯体および軟組織充填物を含有する組成物 |
US20040138103A1 (en) * | 2002-11-07 | 2004-07-15 | Procyte Corporation | Compositions containing peptide copper complexes and metalloproteinase inhibitors and methods related thereto |
US20040142853A1 (en) * | 2002-11-07 | 2004-07-22 | Procyte Corporation | Stimulation of hair growth by compositions containing peptide copper complexes and minoxidil |
US7128923B2 (en) * | 2003-03-31 | 2006-10-31 | Procyte Corporation | Preserved and stable compositions containing peptide copper complexes and method related thereto |
US6927205B2 (en) * | 2003-04-28 | 2005-08-09 | Procyte Corporation | Compositions and methods for treatment of psoriasis |
JP2007528356A (ja) * | 2003-04-30 | 2007-10-11 | ペプトロン カンパニー リミテッド | ペプチドが結合したビタミンc誘導体、その製造方法およびそれを含む組成物 |
US6927206B2 (en) * | 2003-06-06 | 2005-08-09 | Procyte Corporation | Compositions and methods for treatment of rosacea |
WO2005097061A1 (en) * | 2004-04-01 | 2005-10-20 | Procyte Corporation | Encapsulated peptide copper complexes and compositions and methods related thereto |
US20060052287A1 (en) * | 2004-08-18 | 2006-03-09 | Procyte Corporation | Polyethylene glycol - peptide copper complexes and compositions and methods related thereto |
US7687650B2 (en) | 2006-02-03 | 2010-03-30 | Jr Chem, Llc | Chemical compositions and methods of making them |
CA2641420C (en) | 2006-02-03 | 2013-06-25 | Jr Chem, Llc | Anti-aging treatment using copper and zinc compositions |
US7897800B2 (en) | 2006-02-03 | 2011-03-01 | Jr Chem, Llc | Chemical compositions and methods of making them |
KR100691540B1 (ko) | 2006-06-22 | 2007-03-12 | 주식회사 펩트론 | 펩타이드가 결합된 안정화된 비타민 c 유도체, 이의제조방법 및 이를 함유하는 조성물 |
US7867522B2 (en) | 2006-09-28 | 2011-01-11 | Jr Chem, Llc | Method of wound/burn healing using copper-zinc compositions |
US8273791B2 (en) | 2008-01-04 | 2012-09-25 | Jr Chem, Llc | Compositions, kits and regimens for the treatment of skin, especially décolletage |
WO2010085753A1 (en) | 2009-01-23 | 2010-07-29 | Jr Chem, Llc | Rosacea treatments and kits for performing them |
US8952057B2 (en) | 2011-01-11 | 2015-02-10 | Jr Chem, Llc | Compositions for anorectal use and methods for treating anorectal disorders |
US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3194732A (en) * | 1960-10-03 | 1965-07-13 | Neuhauser Irene | Assisting healing of skin-denuded areas on the body with dried non-fibrous egg-shellmembrane products and compositions therefor |
US3558770A (en) * | 1967-09-01 | 1971-01-26 | Kraftco Corp | Wound treating composition employing an enzyme modified casein |
US3551554A (en) * | 1968-08-16 | 1970-12-29 | Crown Zellerbach Corp | Enhancing tissue penetration of physiologically active agents with dmso |
US3767784A (en) * | 1970-12-01 | 1973-10-23 | S Gluck | Composition for the protection and treatment of injured body tissue and method of utilizing the same |
US3832338A (en) * | 1972-03-23 | 1974-08-27 | Diagnostic Data Inc | Orgotein production using a buffer solution containing divalent metal salts |
US3758682A (en) * | 1972-03-23 | 1973-09-11 | Diagnostics Data Inc | Pharmaceutical compositions comprising orgotein and their use |
US4022888A (en) * | 1975-09-09 | 1977-05-10 | Diagnostic Data, Inc. | Esterified orgotein |
DE2700043C2 (de) * | 1977-01-03 | 1983-12-08 | Thera Gesellschaft für Patentverwertung mbH, 8036 Herrsching | Mittel zur Verbesserung der Durchblutung und Wundheilung |
US4167945A (en) * | 1977-01-31 | 1979-09-18 | Gottlieb Sheldon K | Method for enhancing the healing of grafted tissue |
US4287184A (en) * | 1977-11-23 | 1981-09-01 | The Massachusetts General Hospital | Process for healing wounds |
US4263428A (en) * | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
US4440788A (en) * | 1980-05-13 | 1984-04-03 | Mitsubishi Chemical Industries, Limited | Cysteine derivatives |
US4461724A (en) * | 1981-10-28 | 1984-07-24 | Nippon Zoki Pharmaceutical Co., Ltd. | Peptide compounds, a process for manufacturing them, pharmaceutical compositions containing them, and methods for treating ulcer and thrombus with them |
HU193289B (en) * | 1984-06-19 | 1987-09-28 | Universal Vegyipari Szoevetkez | Cosmetical composition for treating hair and nail containing blood plasma concentrate as active agent |
US4937230A (en) * | 1985-01-24 | 1990-06-26 | Procyte Corporation | Method of healing wounds in horses |
US4760051A (en) * | 1985-01-24 | 1988-07-26 | Pickart Loren R | Use of GHL-Cu as a wound-healing and anti-inflammatory agent |
US4584284A (en) * | 1985-01-31 | 1986-04-22 | Ortho Pharmaceutical Corporation | Bursopoietin |
US4810693A (en) * | 1985-02-08 | 1989-03-07 | Procyte Corporation | Method for inducing biological coverings in wounds |
US4767753A (en) * | 1985-02-08 | 1988-08-30 | Procyte Corporation | Methods and compositions for preventing ulcers |
US4665054A (en) * | 1985-02-08 | 1987-05-12 | Bioheal, Inc. | Chemical derivatives of GHL-Cu |
US4877770A (en) * | 1985-02-08 | 1989-10-31 | Procyte Corporation | Chemical derivatives of GHL-Cu |
-
1989
- 1989-08-30 US US07/401,312 patent/US5023237A/en not_active Expired - Fee Related
-
1990
- 1990-08-28 CA CA002065416A patent/CA2065416A1/en not_active Abandoned
- 1990-08-28 EP EP90914339A patent/EP0489860B1/en not_active Expired - Lifetime
- 1990-08-28 DK DK90914339.8T patent/DK0489860T3/da active
- 1990-08-28 DE DE69021386T patent/DE69021386T2/de not_active Expired - Fee Related
- 1990-08-28 AU AU64294/90A patent/AU648517B2/en not_active Ceased
- 1990-08-28 ES ES90914339T patent/ES2075219T3/es not_active Expired - Lifetime
- 1990-08-28 KR KR1019920700448A patent/KR920703627A/ko active IP Right Grant
- 1990-08-28 WO PCT/US1990/004847 patent/WO1991003488A1/en active IP Right Grant
- 1990-08-28 JP JP2513399A patent/JPH05500221A/ja active Pending
- 1990-08-28 AT AT90914339T patent/ATE125820T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU648517B2 (en) | 1994-04-28 |
CA2065416A1 (en) | 1991-03-01 |
WO1991003488A1 (en) | 1991-03-21 |
AU6429490A (en) | 1991-04-08 |
JPH05500221A (ja) | 1993-01-21 |
DK0489860T3 (da) | 1995-12-11 |
EP0489860A1 (en) | 1992-06-17 |
EP0489860B1 (en) | 1995-08-02 |
ATE125820T1 (de) | 1995-08-15 |
KR920703627A (ko) | 1992-12-18 |
DE69021386D1 (de) | 1995-09-07 |
US5023237A (en) | 1991-06-11 |
DE69021386T2 (de) | 1996-01-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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