ES2069739T3 - Modulos de ensayo para diagnostico. - Google Patents

Modulos de ensayo para diagnostico.

Info

Publication number
ES2069739T3
ES2069739T3 ES90909858T ES90909858T ES2069739T3 ES 2069739 T3 ES2069739 T3 ES 2069739T3 ES 90909858 T ES90909858 T ES 90909858T ES 90909858 T ES90909858 T ES 90909858T ES 2069739 T3 ES2069739 T3 ES 2069739T3
Authority
ES
Spain
Prior art keywords
fluid
test
developed
sample
reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90909858T
Other languages
English (en)
Inventor
Mark Stander Bowen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Behring Diagnostics Inc
Original Assignee
Behring Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behring Diagnostics Inc filed Critical Behring Diagnostics Inc
Application granted granted Critical
Publication of ES2069739T3 publication Critical patent/ES2069739T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Dispersion Chemistry (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Cooling Or The Like Of Semiconductors Or Solid State Devices (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Optical Measuring Cells (AREA)

Abstract

UN MODULO DE PRUEBA DE DIAGNOSTICO PARA PROCEDIMIENTOS ANALITICOS EN EL QUE UNA SEÑAL OPTICA, DESARROLLADA POR LA INTERACCION ENTRE UN COMPONENTE DE UN FLUIDO DE MUESTRA, COMO UNA ANALITA EN UN FLUIDO BIOLOGICO, Y UNO O MAS REAGENTES EN UN ELEMENTO DE ENSAYO RESISTENTE (12), SE LEE POR MEDIOS OPTICOS. EL MODULO ESTA FORMADO POR UN PRIMER ELEMENTO (10) CON UNA CARA ABIERTA Y UN SEGUNDO ELEMENTO (12) AL QUE SE APLICA EL FLUIDO DE MUESTRA Y DONDE SE LEE LA SEÑAL OPTICA DESARROLLADA MEDIANTE LA INTERACCION DEL COMPONENTE DE MUESTRA Y EL (LOS) REAGENTE (S) EN EL ELEMENTO DE ENSAYO (12) SE MANTIENE EN UNA ORIENTACION HORIZONTAL MEDIANTE LA FLEXION DESARROLLADA ENTRE LAS SUPERFICIES DE RAMPA COMPLEMENTARIAS (44, 46 Y 86, 87) EN LOS ELEMENTOS PRIMERO (10) Y SEGUNDO (14) RESPECTIVAMENTE. EN UNA REALIZACION NORMALIZADA EL PRIMER ELEMENTO (10) DEFINE UNA SUPERFICIE DE TRANSPORTE DE LIQUIDO (38) QUE, JUNTO CON EL ELEMENTO DE ENSAYO (12) FORMA UNA ZONA DE CORRIENTE DE FLUIDO PARA SUMINISTRAR LA EXTENSION UNIFORME DE UN FLUIDO DE MUESTRA, INTRODUCIDO POR UNA ABERTURA (40) EN EL ELEMENTO, A TRAVES DE LA SUPERFICIE DEL ELEMENTO DE ENSAYO. EL VOLUMEN DE FLUIDO EN LA ZONA DE CORRIENTE DE FLUIDO SE CONTROLA POR LA COLOCACION PRECISA DEL ELEMENTOS DE ENSAYO SEGUN LA INVENCION.
ES90909858T 1989-07-19 1990-06-19 Modulos de ensayo para diagnostico. Expired - Lifetime ES2069739T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/382,552 US5053197A (en) 1989-07-19 1989-07-19 Diagnostic assay module

Publications (1)

Publication Number Publication Date
ES2069739T3 true ES2069739T3 (es) 1995-05-16

Family

ID=23509472

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90909858T Expired - Lifetime ES2069739T3 (es) 1989-07-19 1990-06-19 Modulos de ensayo para diagnostico.

Country Status (9)

Country Link
US (1) US5053197A (es)
EP (1) EP0434798B1 (es)
JP (1) JPH03505182A (es)
AT (1) ATE116871T1 (es)
CA (1) CA2019873C (es)
DE (1) DE69015992T2 (es)
DK (1) DK0434798T3 (es)
ES (1) ES2069739T3 (es)
WO (1) WO1991001179A1 (es)

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AU635008B2 (en) * 1989-12-13 1993-03-11 Genelabs Diagnostics Pte Ltd Analytical apparatus and method for automated blot assay
US5290517A (en) * 1990-04-04 1994-03-01 Westinghouse Electric Corp. Optical agglutination assay device
US5219526A (en) * 1990-04-27 1993-06-15 Pb Diagnostic Systems Inc. Assay cartridge
US5167922A (en) * 1990-04-27 1992-12-01 Pb Diagnostic Systems Inc. Assay cartridge
EP0573572B1 (en) * 1991-02-27 1998-01-21 Boehringer Mannheim Corporation Improved test strip
US5271895A (en) * 1991-02-27 1993-12-21 Boehringer Mannheim Corporation Test strip
US5820826A (en) * 1992-09-03 1998-10-13 Boehringer Mannheim Company Casing means for analytical test apparatus
US5503985A (en) * 1993-02-18 1996-04-02 Cathey; Cheryl A. Disposable device for diagnostic assays
US5798215A (en) * 1993-02-18 1998-08-25 Biocircuits Corporation Device for use in analyte detection assays
US5399486A (en) * 1993-02-18 1995-03-21 Biocircuits Corporation Disposable unit in diagnostic assays
CA2170402C (en) * 1993-08-24 2000-07-18 Michael P. Allen Novel disposable electronic assay device
US5728352A (en) * 1994-11-14 1998-03-17 Advanced Care Products Disposable electronic diagnostic instrument
US6184040B1 (en) * 1998-02-12 2001-02-06 Polaroid Corporation Diagnostic assay system and method
US6146591A (en) * 1998-05-01 2000-11-14 Miller; C David Biochemical detection system for rapid determination of the presence of toxins, bacteria, and other substances
US6908770B1 (en) 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
US7022517B1 (en) 1999-07-16 2006-04-04 Board Of Regents, The University Of Texas System Method and apparatus for the delivery of samples to a chemical sensor array
WO2001006244A2 (en) 1999-07-16 2001-01-25 Board Of Regents, The University Of Texas System General signaling protocols for chemical receptors in immobilized matrices
WO2001011374A2 (en) 1999-08-06 2001-02-15 Thermo Biostar, Inc. An automated point of care detection system including complete sample processing capabilities
DE60135092D1 (de) 2000-01-31 2008-09-11 Univ Texas Tragbare vorrichtung mit einer sensor-array-anordnung
WO2002054052A1 (en) * 2001-01-08 2002-07-11 Leonard Fish Diagnostic instruments and methods for detecting analytes
US7459127B2 (en) 2002-02-26 2008-12-02 Siemens Healthcare Diagnostics Inc. Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces
US8257967B2 (en) 2002-04-26 2012-09-04 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors
US7094354B2 (en) 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US7125711B2 (en) 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
EP1590659A4 (en) * 2003-02-07 2010-04-21 Univ Texas MULTILOSE MICROSPHERE WITH INTEGRATED CHROMATOGRAPHIC AND DETECTION LAYERS FOR USE IN ARRAY SENSORS
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
US7347617B2 (en) 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
US7468160B2 (en) * 2003-12-05 2008-12-23 Agilent Technologies, Inc. Devices and methods for performing array based assays
DE10356951A1 (de) * 2003-12-05 2005-06-30 Human Gesellschaft für Biochemica und Diagnostica mbH Testvorrichtung
EP1695082A2 (en) 2003-12-11 2006-08-30 Board of Regents, The University of Texas System Method and system for the analysis of saliva using a sensor array
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US8105849B2 (en) 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
EP1910824A4 (en) 2005-05-31 2012-11-21 Labnow Inc METHOD AND COMPOSITIONS RELATED TO THE PREPARATION AND USE OF A WHITE BLOOD IMAGE
US20060275852A1 (en) 2005-06-06 2006-12-07 Montagu Jean I Assays based on liquid flow over arrays
US20080026373A1 (en) * 2006-07-26 2008-01-31 Rodionova Natalia A Assays Based On Light Emission From Analyte Complexes Within A Cassette
ES2453379T3 (es) * 2007-04-25 2014-04-07 3M Innovative Properties Company Reactivos soportados, métodos y dispositivos
KR20100017126A (ko) * 2007-04-25 2010-02-16 쓰리엠 이노베이티브 프로퍼티즈 컴파니 화학적 요소 및 처리 장치 조립체
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Also Published As

Publication number Publication date
JPH03505182A (ja) 1991-11-14
CA2019873C (en) 1995-09-19
EP0434798B1 (en) 1995-01-11
ATE116871T1 (de) 1995-01-15
CA2019873A1 (en) 1991-01-19
DE69015992T2 (de) 1995-06-08
EP0434798A1 (en) 1991-07-03
US5053197A (en) 1991-10-01
DE69015992D1 (de) 1995-02-23
WO1991001179A1 (en) 1991-02-07
DK0434798T3 (da) 1995-03-27
JPH0536101B2 (es) 1993-05-28

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