ES2061982T5 - Activador de plasminogeno y agente trombolitico. - Google Patents

Activador de plasminogeno y agente trombolitico.

Info

Publication number
ES2061982T5
ES2061982T5 ES89303742T ES89303742T ES2061982T5 ES 2061982 T5 ES2061982 T5 ES 2061982T5 ES 89303742 T ES89303742 T ES 89303742T ES 89303742 T ES89303742 T ES 89303742T ES 2061982 T5 ES2061982 T5 ES 2061982T5
Authority
ES
Spain
Prior art keywords
staphylokinase
plasminogen activator
thrombolytic agent
agent
plasminogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89303742T
Other languages
English (en)
Other versions
ES2061982T3 (es
Inventor
Masashi Sakai
Osamu Matsuo
Masaaki Watanuki
Toshizo Sakurai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yakult Honsha Co Ltd
Original Assignee
Yakult Honsha Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26348760&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2061982(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP63090252A external-priority patent/JP2707273B2/ja
Priority claimed from JP1013044A external-priority patent/JP2627950B2/ja
Application filed by Yakult Honsha Co Ltd filed Critical Yakult Honsha Co Ltd
Application granted granted Critical
Publication of ES2061982T3 publication Critical patent/ES2061982T3/es
Publication of ES2061982T5 publication Critical patent/ES2061982T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

AGENTE TROMBOLITICO QUE CONTIENE ESTAFILOQUINASA COMO INGREDIENTE ACTIVO; LA ESTAFILOQUINASA ES UN ACTIVADOR DE PLASMINOGENO PRODUCIDO POR EL STAPHYLOCOCCUS AUREUS. EL AGENTE SE PUEDE EMPLEAR TERAPEUTICAMENTE EN EL TRATAMIENTO DE ENFERMEDADES TROMBOSICAS TALES COMO INFARTO DE MIOCARDIO Y ESCLEROSIS ARTERIAL. EL AGENTE TROMBOLITICO TIENE UN TIEMPO DE RETARDO MEJORADO A CONCENTRACIONES ALTAS POR FORMACION DE UN COMPLEJO ENTRE ESTAFILOQUINASA Y PLASMINOGENO (O PLASMINA).
ES89303742T 1988-04-14 1989-04-14 Activador de plasminogeno y agente trombolitico. Expired - Lifetime ES2061982T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63090252A JP2707273B2 (ja) 1988-04-14 1988-04-14 血栓溶解剤
JP1013044A JP2627950B2 (ja) 1989-01-24 1989-01-24 プラスミノーゲンアクチベータ及び血栓溶解剤

Publications (2)

Publication Number Publication Date
ES2061982T3 ES2061982T3 (es) 1994-12-16
ES2061982T5 true ES2061982T5 (es) 1999-03-16

Family

ID=26348760

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89303742T Expired - Lifetime ES2061982T5 (es) 1988-04-14 1989-04-14 Activador de plasminogeno y agente trombolitico.

Country Status (5)

Country Link
EP (1) EP0337817B2 (es)
KR (1) KR0135980B1 (es)
CA (1) CA1339211C (es)
DE (1) DE68912383T3 (es)
ES (1) ES2061982T5 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2107525T3 (es) * 1990-12-17 1997-12-01 Yakult Honsha Kk Peptido trombolitico, su produccion y agente trombolitico.
ATE147989T1 (de) * 1991-06-28 1997-02-15 Leuven Res & Dev Vzw Verwendung von staphylokinase für die herstellung einer zusammensetzung für die behandlung von gefässthrombose
DE4411143C2 (de) * 1994-03-30 1996-08-01 Immuno Ag Thrombosemittel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5867181A (ja) * 1981-10-16 1983-04-21 Yakult Honsha Co Ltd スタフイロキナーゼ産生遺伝情報を担うｄｎａ断片組み換え体ｄｎａおよびそれを導入した大腸菌

Also Published As

Publication number Publication date
EP0337817B2 (en) 1998-12-16
EP0337817A3 (en) 1990-08-29
CA1339211C (en) 1997-08-05
KR900015752A (ko) 1990-11-10
DE68912383D1 (de) 1994-03-03
DE68912383T3 (de) 1999-06-02
EP0337817B1 (en) 1994-01-19
ES2061982T3 (es) 1994-12-16
DE68912383T2 (de) 1994-07-14
KR0135980B1 (ko) 1998-04-25
EP0337817A2 (en) 1989-10-18

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