ES2061853T3 - Utilizacion de inhibidores de la eca contra la formacion de neointimas despues de lesion vascular. - Google Patents

Utilizacion de inhibidores de la eca contra la formacion de neointimas despues de lesion vascular.

Info

Publication number
ES2061853T3
ES2061853T3 ES89117050T ES89117050T ES2061853T3 ES 2061853 T3 ES2061853 T3 ES 2061853T3 ES 89117050 T ES89117050 T ES 89117050T ES 89117050 T ES89117050 T ES 89117050T ES 2061853 T3 ES2061853 T3 ES 2061853T3
Authority
ES
Spain
Prior art keywords
formation
ace inhibitors
intimates
neo
vascular injury
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89117050T
Other languages
English (en)
Inventor
Hans Rudolf Prof D Baumgartner
Jean-Paul Dr Clozel
Fridolin Dr Hefti
Markus Dr Hosang
Herbert Dr Kuhn
Rita Muller
Jerry Dr Powell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2061853T3 publication Critical patent/ES2061853T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Prostheses (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

LOS INHIBIDORES ACE PUEDEN SUPRIMIR LA FORMACION DE NEOINTIMA Y LA REDUCCION DE VOLUMEN DE RECIPIENTE MEDIANTE EL ESPESAMIENTO DE LA PARED DEL RECIPIENTE. LOS INHIBIDORES ACE SE UTILIZAN PARA EL TRATAMIENTO Y EL IMPEDIMIENTO DE FORMACIONES DE NEOINTIMA EN RECIPIENTES DETERIORADOS, ES DECIR, IUMPEDIR FORMACIONES DE RESTOS ARTERIALES EN ANGIOPLASTIA O EN CIRUGIA CARDIOVASCULAR.
ES89117050T 1988-09-14 1989-09-14 Utilizacion de inhibidores de la eca contra la formacion de neointimas despues de lesion vascular. Expired - Lifetime ES2061853T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH342188 1988-09-14

Publications (1)

Publication Number Publication Date
ES2061853T3 true ES2061853T3 (es) 1994-12-16

Family

ID=4255625

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89117050T Expired - Lifetime ES2061853T3 (es) 1988-09-14 1989-09-14 Utilizacion de inhibidores de la eca contra la formacion de neointimas despues de lesion vascular.

Country Status (13)

Country Link
EP (1) EP0363671B1 (es)
JP (1) JPH02121922A (es)
KR (1) KR900004337A (es)
AT (1) ATE100716T1 (es)
AU (1) AU625693B2 (es)
DE (1) DE58906814D1 (es)
DK (1) DK452089A (es)
ES (1) ES2061853T3 (es)
HU (1) HU206186B (es)
IE (1) IE892931L (es)
IL (1) IL91572A (es)
PT (1) PT91705B (es)
ZA (1) ZA896851B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3925759A1 (de) * 1989-08-03 1991-02-07 Thera Patent Verwaltungs Gmbh Verwendung von ace-inhibitoren fuer die atheroskleroseprophylaxe
DE3926606A1 (de) * 1989-08-11 1991-02-14 Hoechst Ag Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie
US5212165A (en) * 1989-10-23 1993-05-18 E. R. Squibb & Sons, Inc. Method for rehabilitating the vasorelaxant action of the coronary arteries impaired through atherosclerosis or hypercholesterolemia employing an ace inhibitor
US5061694A (en) * 1989-10-23 1991-10-29 E. R. Squibb & Sons, Inc. Method for stabilizing or causing regression of atherosclerosis in coronary arteries employing an ace inhibitor
CA2042159A1 (en) * 1990-05-31 1991-12-01 Miguel A. Ondetti Method for preventing onset of restenosis after angioplasty employing an ace inhibitor
US5140012A (en) * 1990-05-31 1992-08-18 E. R. Squibb & Sons, Inc. Method for preventing onset of restenosis after angioplasty employing pravastatin
CA2052014A1 (en) * 1990-10-19 1992-04-20 Henry Y. Pan Method for preventing diabetic complications employing a cholesterol lowering drug alone or in combination with an ace inhibitor
DK0682947T3 (da) 1994-05-19 1998-05-04 Mitsubishi Chem Corp Medikament til terapeutisk og profylaktisk behandling af sygdomme forårsaget af glatmuskelcelle-hyperplasi
ATE206433T1 (de) * 1995-03-24 2001-10-15 Molecumetics Ltd Beta-schleifenähnliche verbindungen und deren verwendung als protease-inhibitoren
ES2201266T3 (es) * 1996-01-17 2004-03-16 Taiho Pharmaceutical Company Limited Inhibidores del espesamiento de la capa intima.
SI1216038T1 (sl) * 1999-08-30 2006-02-28 Sanofi Aventis Deutschland Ramipril za preprecevanje kardiovaskularnih dogodkov
JP4904859B2 (ja) * 2006-03-13 2012-03-28 大日本印刷株式会社 印刷ユニットおよびドクターブレードの研磨方法
CN101478983A (zh) * 2006-07-10 2009-07-08 特瓦制药工业有限公司 含有对水分敏感的药物和第二药物的组合的稳定制剂及其制造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4316906A (en) 1978-08-11 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of substituted prolines
AT377496B (de) 1981-06-19 1985-03-25 Voith Gmbh J M Vorrichtung zum anwickeln einer warenbahn auf eine neu eingelegte wickelhuelse in einer doppeltragwalzen-wickelmaschine

Also Published As

Publication number Publication date
ZA896851B (en) 1990-06-27
EP0363671A2 (de) 1990-04-18
HUT51148A (en) 1990-04-28
IL91572A0 (en) 1990-04-29
DK452089A (da) 1990-03-15
PT91705B (pt) 1995-05-31
PT91705A (pt) 1990-03-30
DK452089D0 (da) 1989-09-13
HU206186B (en) 1992-09-28
AU4124089A (en) 1990-03-22
AU625693B2 (en) 1992-07-16
JPH02121922A (ja) 1990-05-09
EP0363671A3 (de) 1991-12-11
IL91572A (en) 1994-01-25
ATE100716T1 (de) 1994-02-15
DE58906814D1 (de) 1994-03-10
IE892931L (en) 1990-03-14
EP0363671B1 (de) 1994-01-26
KR900004337A (ko) 1990-04-12

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