ES2061713T3 - Nuevas formas galenicas de corticoides para administracion por via per- y sublingual y su procedimiento de preparacion. - Google Patents
Nuevas formas galenicas de corticoides para administracion por via per- y sublingual y su procedimiento de preparacion.Info
- Publication number
- ES2061713T3 ES2061713T3 ES88420340T ES88420340T ES2061713T3 ES 2061713 T3 ES2061713 T3 ES 2061713T3 ES 88420340 T ES88420340 T ES 88420340T ES 88420340 T ES88420340 T ES 88420340T ES 2061713 T3 ES2061713 T3 ES 2061713T3
- Authority
- ES
- Spain
- Prior art keywords
- corticoid
- impregnation
- corticoids
- administration
- per
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
EN ESTAS NUEVAS FORMAS GALEMICAS EL CORTICOIDE ESTA CONTENIDO EN CANTIDADES ESTRICTAMENTE CONTROLADAS Y REPRODUCIBLES, EN SOPORTES SOLIDOS PREVISTOS PARA UNA LIBERACION PROGRESIVA DEL PRINCIPIO ACTIVO POR VIA PER Y SUBLINGUAL. PREFERENTEMENTE EL CORTICOIDE ES EL METIL PREDRISOLONA. SU PROCEDIMIENTO DE PREPARACION COMPORTA LAS ETAPAS SIGUIENTES: PUESTA EN SOLUCION DEL CORTICOIDE EN UN DISOLVENTE; PREPARACION DE DISOLUCIONES DE DIFERENTES CONCENTRACIONES; FRACCIONAMIENTO DE CADA UNA DE LAS DILUCIONES EN BAJO - DILUCIONES; IMPREGNACION POR MULTI IMPREGNACION O IMPREGNACION FRACCIONADA DE UN SOPORTE SOLIDO FARMACEUTICAMENTE ACEPTABLE CON CADA UNA DE LAS BAJO DILUCIONES; CADA UNA DE DICHAS ETAPAS DE IMPREGNACION ESTA SEGUIDA POR UN SECADO DE AIRE FORZADO Y DESECADO A UNA TEMPERATURA INFERIOR O IGUAL A 35 (GRADOS) C.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8714476A FR2621483B1 (fr) | 1987-10-08 | 1987-10-08 | Nouvelles formes galeniques de corticoides pour administration par voie per- et sublinguale et leur procede de preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2061713T3 true ES2061713T3 (es) | 1994-12-16 |
Family
ID=9355988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88420340T Expired - Lifetime ES2061713T3 (es) | 1987-10-08 | 1988-10-07 | Nuevas formas galenicas de corticoides para administracion por via per- y sublingual y su procedimiento de preparacion. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5061493A (es) |
EP (1) | EP0311540B1 (es) |
JP (1) | JPH01128928A (es) |
AT (1) | ATE99940T1 (es) |
CA (1) | CA1328610C (es) |
DE (1) | DE3887066T2 (es) |
ES (1) | ES2061713T3 (es) |
FR (1) | FR2621483B1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5785966A (en) * | 1994-06-15 | 1998-07-28 | Coles; John G. | Inhibition of human xenogenic or allogenic antibodies to reduce xenograft or allograft rejection in human recipients |
FR2766367B1 (fr) * | 1997-07-22 | 2000-03-31 | Plantes Et Medecines | Granules homeopathiques et procede de fabrication |
WO1999040898A2 (en) * | 1998-02-12 | 1999-08-19 | Centrapharm Inc. | Sublingual drug formulations having combined rapid onset of action and long lasting therapeutic effect |
IT1318618B1 (it) * | 2000-07-10 | 2003-08-27 | A C R Applied Coating Res S A | Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi. |
EP2468266A3 (en) * | 2004-04-22 | 2012-10-24 | AcuCort AB | Pharmaceutical compositions for acute glucocorticoid therapy |
FR2883179B1 (fr) * | 2005-03-18 | 2009-04-17 | Ethypharm Sa | Comprime enrobe |
EP2910240B1 (en) * | 2014-02-25 | 2021-07-07 | Biologische Heilmittel Heel GmbH | Method for the manufacture of globules |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH156609A (de) * | 1931-01-27 | 1932-08-15 | Chem Pharm Lab Bika V Poehlman | Verfahren zur Herstellung eines trockenen, homöopathischen Heilmittels. |
GB1171691A (en) * | 1967-02-24 | 1969-11-26 | Forest Laboratories | Lond-Acting Oral Carrier |
JPS5138412A (en) * | 1974-09-24 | 1976-03-31 | Nippon Kayaku Kk | Kokoseizai no seiho |
US4279900A (en) * | 1978-07-13 | 1981-07-21 | Intrex Research Corporation | Prodrugs for the improved delivery of halogen-containing glucocorticosteroids |
JPS5562012A (en) * | 1978-11-06 | 1980-05-10 | Teijin Ltd | Slow-releasing preparation |
US4259314A (en) * | 1979-12-10 | 1981-03-31 | Hans Lowey | Method and composition for the preparation of controlled long-acting pharmaceuticals |
FR2471186A1 (fr) * | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation |
JPS5924964B2 (ja) * | 1981-08-11 | 1984-06-13 | 帝人株式会社 | 徐放性製剤 |
GB8514665D0 (en) * | 1985-06-11 | 1985-07-10 | Eroceltique Sa | Oral pharmaceutical composition |
-
1987
- 1987-10-08 FR FR8714476A patent/FR2621483B1/fr not_active Expired - Fee Related
-
1988
- 1988-09-28 CA CA000578698A patent/CA1328610C/fr not_active Expired - Fee Related
- 1988-10-07 ES ES88420340T patent/ES2061713T3/es not_active Expired - Lifetime
- 1988-10-07 DE DE88420340T patent/DE3887066T2/de not_active Expired - Fee Related
- 1988-10-07 US US07/254,602 patent/US5061493A/en not_active Expired - Fee Related
- 1988-10-07 EP EP88420340A patent/EP0311540B1/fr not_active Expired - Lifetime
- 1988-10-07 AT AT88420340T patent/ATE99940T1/de not_active IP Right Cessation
- 1988-10-07 JP JP63252194A patent/JPH01128928A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
FR2621483B1 (fr) | 1991-09-20 |
US5061493A (en) | 1991-10-29 |
FR2621483A1 (fr) | 1989-04-14 |
DE3887066T2 (de) | 1994-05-11 |
CA1328610C (fr) | 1994-04-19 |
EP0311540B1 (fr) | 1994-01-12 |
JPH01128928A (ja) | 1989-05-22 |
DE3887066D1 (de) | 1994-02-24 |
ATE99940T1 (de) | 1994-01-15 |
EP0311540A1 (fr) | 1989-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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