ES2061713T3 - Nuevas formas galenicas de corticoides para administracion por via per- y sublingual y su procedimiento de preparacion. - Google Patents

Nuevas formas galenicas de corticoides para administracion por via per- y sublingual y su procedimiento de preparacion.

Info

Publication number
ES2061713T3
ES2061713T3 ES88420340T ES88420340T ES2061713T3 ES 2061713 T3 ES2061713 T3 ES 2061713T3 ES 88420340 T ES88420340 T ES 88420340T ES 88420340 T ES88420340 T ES 88420340T ES 2061713 T3 ES2061713 T3 ES 2061713T3
Authority
ES
Spain
Prior art keywords
corticoid
impregnation
corticoids
administration
per
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88420340T
Other languages
English (en)
Inventor
Epouse Ayache Josiane Clairet
Jean-Jacques Ayache
Georges Bruttmann
Patrick Pedrali
Serge Robert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medibrevex
Original Assignee
Medibrevex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medibrevex filed Critical Medibrevex
Application granted granted Critical
Publication of ES2061713T3 publication Critical patent/ES2061713T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

EN ESTAS NUEVAS FORMAS GALEMICAS EL CORTICOIDE ESTA CONTENIDO EN CANTIDADES ESTRICTAMENTE CONTROLADAS Y REPRODUCIBLES, EN SOPORTES SOLIDOS PREVISTOS PARA UNA LIBERACION PROGRESIVA DEL PRINCIPIO ACTIVO POR VIA PER Y SUBLINGUAL. PREFERENTEMENTE EL CORTICOIDE ES EL METIL PREDRISOLONA. SU PROCEDIMIENTO DE PREPARACION COMPORTA LAS ETAPAS SIGUIENTES: PUESTA EN SOLUCION DEL CORTICOIDE EN UN DISOLVENTE; PREPARACION DE DISOLUCIONES DE DIFERENTES CONCENTRACIONES; FRACCIONAMIENTO DE CADA UNA DE LAS DILUCIONES EN BAJO - DILUCIONES; IMPREGNACION POR MULTI IMPREGNACION O IMPREGNACION FRACCIONADA DE UN SOPORTE SOLIDO FARMACEUTICAMENTE ACEPTABLE CON CADA UNA DE LAS BAJO DILUCIONES; CADA UNA DE DICHAS ETAPAS DE IMPREGNACION ESTA SEGUIDA POR UN SECADO DE AIRE FORZADO Y DESECADO A UNA TEMPERATURA INFERIOR O IGUAL A 35 (GRADOS) C.
ES88420340T 1987-10-08 1988-10-07 Nuevas formas galenicas de corticoides para administracion por via per- y sublingual y su procedimiento de preparacion. Expired - Lifetime ES2061713T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8714476A FR2621483B1 (fr) 1987-10-08 1987-10-08 Nouvelles formes galeniques de corticoides pour administration par voie per- et sublinguale et leur procede de preparation

Publications (1)

Publication Number Publication Date
ES2061713T3 true ES2061713T3 (es) 1994-12-16

Family

ID=9355988

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88420340T Expired - Lifetime ES2061713T3 (es) 1987-10-08 1988-10-07 Nuevas formas galenicas de corticoides para administracion por via per- y sublingual y su procedimiento de preparacion.

Country Status (8)

Country Link
US (1) US5061493A (es)
EP (1) EP0311540B1 (es)
JP (1) JPH01128928A (es)
AT (1) ATE99940T1 (es)
CA (1) CA1328610C (es)
DE (1) DE3887066T2 (es)
ES (1) ES2061713T3 (es)
FR (1) FR2621483B1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5785966A (en) * 1994-06-15 1998-07-28 Coles; John G. Inhibition of human xenogenic or allogenic antibodies to reduce xenograft or allograft rejection in human recipients
FR2766367B1 (fr) * 1997-07-22 2000-03-31 Plantes Et Medecines Granules homeopathiques et procede de fabrication
WO1999040898A2 (en) * 1998-02-12 1999-08-19 Centrapharm Inc. Sublingual drug formulations having combined rapid onset of action and long lasting therapeutic effect
IT1318618B1 (it) * 2000-07-10 2003-08-27 A C R Applied Coating Res S A Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi.
EP2468266A3 (en) * 2004-04-22 2012-10-24 AcuCort AB Pharmaceutical compositions for acute glucocorticoid therapy
FR2883179B1 (fr) * 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
EP2910240B1 (en) * 2014-02-25 2021-07-07 Biologische Heilmittel Heel GmbH Method for the manufacture of globules

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH156609A (de) * 1931-01-27 1932-08-15 Chem Pharm Lab Bika V Poehlman Verfahren zur Herstellung eines trockenen, homöopathischen Heilmittels.
GB1171691A (en) * 1967-02-24 1969-11-26 Forest Laboratories Lond-Acting Oral Carrier
JPS5138412A (en) * 1974-09-24 1976-03-31 Nippon Kayaku Kk Kokoseizai no seiho
US4279900A (en) * 1978-07-13 1981-07-21 Intrex Research Corporation Prodrugs for the improved delivery of halogen-containing glucocorticosteroids
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
US4259314A (en) * 1979-12-10 1981-03-31 Hans Lowey Method and composition for the preparation of controlled long-acting pharmaceuticals
FR2471186A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
JPS5924964B2 (ja) * 1981-08-11 1984-06-13 帝人株式会社 徐放性製剤
GB8514665D0 (en) * 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition

Also Published As

Publication number Publication date
FR2621483B1 (fr) 1991-09-20
US5061493A (en) 1991-10-29
FR2621483A1 (fr) 1989-04-14
DE3887066T2 (de) 1994-05-11
CA1328610C (fr) 1994-04-19
EP0311540B1 (fr) 1994-01-12
JPH01128928A (ja) 1989-05-22
DE3887066D1 (de) 1994-02-24
ATE99940T1 (de) 1994-01-15
EP0311540A1 (fr) 1989-04-12

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