ES2061593T3 - Medicamento,2-isoxazolinas e isoxazoles con contenido de fosforo contenidos en el, asi como procedimiento de preparacion para estos compuestos heterociclicos. - Google Patents

Medicamento,2-isoxazolinas e isoxazoles con contenido de fosforo contenidos en el, asi como procedimiento de preparacion para estos compuestos heterociclicos.

Info

Publication number
ES2061593T3
ES2061593T3 ES88117519T ES88117519T ES2061593T3 ES 2061593 T3 ES2061593 T3 ES 2061593T3 ES 88117519 T ES88117519 T ES 88117519T ES 88117519 T ES88117519 T ES 88117519T ES 2061593 T3 ES2061593 T3 ES 2061593T3
Authority
ES
Spain
Prior art keywords
isoxazolines
isoxazoles
hetero
medication
content
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88117519T
Other languages
English (en)
Inventor
Wilfried Dr Schwab
Robert Ryder Dr Bartlett
Ulrich Dr Gebert
Hans Ulrich Dr Schorlemmer
Gerhard Dr Dickneite
Hans Harald Dr Sedlacek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2061593T3 publication Critical patent/ES2061593T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/653—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

MEDICAMENTOS CON UN CONTENIDO O COMPUESTOS DE AL MENOS UN COMPUESTO DE LA FORMULA(I) Y/O EN SU CASO UNA DE SUS SALES DE TOLERANCIA FISIOLOGICA, DONDE LOS COMPUESTOS DE LA FORMULA(I) PUEDEN PRESENTARSE EN SU CASO COMO ESTEREOISOMEROS PUROS O COMO SUS MEZCLAS; LA FORMULA(I) ES: DONDE R1 ES RESTO ORGANICO O HALOGENO; A ES ENLACE SIMPLE C - C O DOBLE; N ES 0, 1 O 2; Y X Y Y SON RESTO ALQUILO O SON - OR2 O - NR2R3 CON R2 Y R3 H O EN SU CASO UN RESTO ALIFATICO SUSTITUIDO. LOS MEDICAMENTOS SON ADECUADOS PARA LA PROFILAXIS Y TRATAMIENTO DE NEFERMOS DEL SISTEMA INMUNE, PRINCIPALMENTE DE TUMORES, INFECCIONES Y/O ENFERMOS AUTOINMUNES DE CUERPOS HUMANOS O DE ANIMALES PARA A/ADIRLOS A LAS VACUNAS. UNA PARTE DE LOS COMPUESTOS DE LA FORMULA(I) ES NUEVA; LOS COMPUESTOS SE PUEDEN OBTENER TRAS UN PROCEDIMIENTO ESPECIAL.
ES88117519T 1987-10-26 1988-10-21 Medicamento,2-isoxazolinas e isoxazoles con contenido de fosforo contenidos en el, asi como procedimiento de preparacion para estos compuestos heterociclicos. Expired - Lifetime ES2061593T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873736113 DE3736113A1 (de) 1987-10-26 1987-10-26 Arzneimittel, darin enthaltene phosphorhaltige 2-isoxazoline und isoxazole, sowie herstellungsverfahren fuer diese heterocyclischen verbindungen

Publications (1)

Publication Number Publication Date
ES2061593T3 true ES2061593T3 (es) 1994-12-16

Family

ID=6339046

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88117519T Expired - Lifetime ES2061593T3 (es) 1987-10-26 1988-10-21 Medicamento,2-isoxazolinas e isoxazoles con contenido de fosforo contenidos en el, asi como procedimiento de preparacion para estos compuestos heterociclicos.

Country Status (16)

Country Link
US (1) US5006515A (es)
EP (1) EP0313997B1 (es)
JP (1) JPH01146887A (es)
KR (1) KR890006233A (es)
AT (1) ATE102628T1 (es)
AU (1) AU608076B2 (es)
CA (1) CA1329604C (es)
DE (2) DE3736113A1 (es)
DK (1) DK592988A (es)
ES (1) ES2061593T3 (es)
FI (1) FI89171C (es)
HU (1) HU201332B (es)
IL (1) IL88124A (es)
NZ (1) NZ226697A (es)
PT (1) PT88856B (es)
ZA (1) ZA887930B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0451790A1 (de) * 1990-04-12 1991-10-16 Hoechst Aktiengesellschaft 3,5-disubstituierte 2-Isoxazoline und Isoxazole, Verfahren zu deren Herstellung, diese enthaltende Mittel und ihre Verwendung
MX9301789A (es) * 1992-04-03 1993-10-01 Iaf Biochem Int Nuevos oligopeptidos lipofilicos con actividad inmunomoduladora.
ES2139754T3 (es) * 1993-11-26 2000-02-16 Pfizer 3-fenil-2-isoxazolinas como agentes antiinflamatorios.
CA2345273A1 (en) * 1998-09-25 2000-04-06 Sunol Molecular Corporation Pharmaceutically active compounds and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2549962A1 (de) * 1975-11-07 1977-05-18 Basf Ag Neue isoxazole und verfahren zu ihrer herstellung
DE2549961C2 (de) * 1975-11-07 1982-10-21 Basf Ag, 6700 Ludwigshafen Neue Phosphorsäurederivate, Verfahren zu ihrer Herstellung und Schädlingsbekämpfungsmittel auf Basis dieser Verbindungen
AU563067B2 (en) * 1982-02-27 1987-06-25 Beecham Group Plc Heterocyclic normonyl derivatives
GB8423252D0 (en) * 1984-09-14 1984-10-17 Shell Int Research Ether herbicides

Also Published As

Publication number Publication date
FI89171C (fi) 1993-08-25
EP0313997A3 (en) 1990-05-30
DK592988A (da) 1989-04-27
EP0313997B1 (de) 1994-03-09
IL88124A (en) 1993-01-31
AU608076B2 (en) 1991-03-21
KR890006233A (ko) 1989-06-12
ZA887930B (en) 1989-07-26
FI884911A (fi) 1989-04-27
AU2419588A (en) 1989-04-27
DE3888284D1 (de) 1994-04-14
US5006515A (en) 1991-04-09
NZ226697A (en) 1991-02-26
DE3736113A1 (de) 1989-05-03
EP0313997A2 (de) 1989-05-03
JPH01146887A (ja) 1989-06-08
CA1329604C (en) 1994-05-17
DK592988D0 (da) 1988-10-25
HU201332B (en) 1990-10-28
IL88124A0 (en) 1989-06-30
ATE102628T1 (de) 1994-03-15
PT88856B (pt) 1993-01-29
HUT48265A (en) 1989-05-29
FI89171B (fi) 1993-05-14
FI884911A0 (fi) 1988-10-24

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