ES2060465T3 - Procedimiento para la produccion de preparacion farmaceutica solida. - Google Patents

Procedimiento para la produccion de preparacion farmaceutica solida.

Info

Publication number
ES2060465T3
ES2060465T3 ES92901671T ES92901671T ES2060465T3 ES 2060465 T3 ES2060465 T3 ES 2060465T3 ES 92901671 T ES92901671 T ES 92901671T ES 92901671 T ES92901671 T ES 92901671T ES 2060465 T3 ES2060465 T3 ES 2060465T3
Authority
ES
Spain
Prior art keywords
polymer
amorphous
production
pharmaceutical preparation
solid pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92901671T
Other languages
English (en)
Inventor
Thomas Patrick Molloy
David Lee
Sham Kumar Chopra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Inc
Original Assignee
Glaxo Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919100040A external-priority patent/GB9100040D0/en
Priority claimed from GB919117525A external-priority patent/GB9117525D0/en
Application filed by Glaxo Canada Inc filed Critical Glaxo Canada Inc
Application granted granted Critical
Publication of ES2060465T3 publication Critical patent/ES2060465T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

EL INVENTO PREVE UN METODO PARA LA PRODUCCION DE UN PREPARADO FARMACEUTICO SOLIDO QUE SE CARACTERIZA POR MEZCLAR JUNTOS GRANULOS O PARTICULAS DE UN MEDICAMENTO FINAMENTE DIVIDIDAS, O GRANULOS QUE CONTIENEN UN MEDICAMENTO Y EXCIPIENTES CON CANTIDADES APROPIADAS DE UN REVESTIMIENTO PLASTIFICADOR POLIMERICO AMORFO O PARCIALMENTE AMORFO FINAMENTE DIVIDIDO QUE DISUELVE EL POLIMERO, COMPRIMIENDO LA MEZCLA EN TABLETAS Y CALENTANDO ESTAS A UNA TEMPERATURA EN LA QUE EL NUCLEO SOLIDO SE REVISTE CON UNA PELICULA PROTECTORA, O GRANULANDO LAS PARTICULAS FINAMENTE DIVIDIDAS DE UNA MEMBRANA FORMADA POR UN PLASTIFICANTE POLIMERICO AMORFO O SUSTANCIALMENTE AMORFO QUE DISUELVE EL POLIMERO, Y CUBRIENDO DICHO NUCLEO SOLIDO CON UNA MEZCLA POLIMERICA, CALENTANDO POSTERIORMENTE EL MATERIAL CUBIERTO POR EL POLIMERO A UNA TEMPERATURA EN LA QUE EL POLIMERO AMORFO O SUSTANCIALMENTE AMORFO FORMA UNA PELICULA CONTINUA.
ES92901671T 1991-01-03 1992-01-03 Procedimiento para la produccion de preparacion farmaceutica solida. Expired - Lifetime ES2060465T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919100040A GB9100040D0 (en) 1991-01-03 1991-01-03 Process
GB919117525A GB9117525D0 (en) 1991-08-14 1991-08-14 Process

Publications (1)

Publication Number Publication Date
ES2060465T3 true ES2060465T3 (es) 1994-11-16

Family

ID=26298203

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92901671T Expired - Lifetime ES2060465T3 (es) 1991-01-03 1992-01-03 Procedimiento para la produccion de preparacion farmaceutica solida.

Country Status (8)

Country Link
EP (1) EP0565560B1 (es)
JP (1) JPH06504276A (es)
AT (1) ATE112163T1 (es)
AU (1) AU657514B2 (es)
CA (1) CA2100272A1 (es)
DE (1) DE69200474T2 (es)
ES (1) ES2060465T3 (es)
WO (1) WO1992011845A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2096103T3 (es) * 1992-01-13 1997-03-01 Pfizer Preparacion de comprimidos de resistencia incrementada.
US5358502A (en) * 1993-02-25 1994-10-25 Pfizer Inc PH-triggered osmotic bursting delivery devices
US5536505A (en) * 1993-12-15 1996-07-16 Eastman Chemical Company Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends
US5523095A (en) * 1993-12-15 1996-06-04 Eastman Chemical Company Controlled release matrix system using cellulose acetate/polyvinylpyrrolidone blends
DE29502547U1 (de) * 1995-02-16 1995-03-30 Röhm GmbH, 64293 Darmstadt Thermoplastisches Überzugs- und Bindemittel für Arzneiformen
JP3471977B2 (ja) * 1995-06-02 2003-12-02 信越化学工業株式会社 液体状可塑剤を用いる無溶媒腸溶性コーティング剤で被覆した腸溶性製剤
US5855915A (en) * 1995-06-30 1999-01-05 Baylor University Tablets or biologically acceptable implants for long-term antiinflammatory drug release
US6051607A (en) * 1998-07-02 2000-04-18 Micro Therapeutics, Inc. Vascular embolizing compositions comprising ethyl lactate and methods for their use
DE10114247A1 (de) * 2001-03-22 2002-10-10 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Polymer-Kombination
MXPA05011446A (es) 2003-04-24 2006-05-31 Jagotec Ag Tableta con liberacion retardada con geometria de nucleo definida.
EA015304B1 (ru) 2006-08-03 2011-06-30 Нитек Фарма Аг Лечение ревматоидного заболевания глюкокортикоидами с отсроченным высвобождением
CN106748819A (zh) * 2016-11-21 2017-05-31 河南工业大学 沙丁胺醇苯甲酸盐的制备方法及其晶体结构
CN106748824A (zh) * 2016-11-21 2017-05-31 河南工业大学 一种新的沙丁胺醇药物盐‑沙丁胺醇富马酸盐及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2841528A (en) * 1954-09-21 1958-07-01 Collett & Co As Method of making fused tablets
US2852433A (en) * 1956-03-07 1958-09-16 Eastman Kodak Co Method of making enteric medicament compositions
US3325365A (en) * 1963-04-02 1967-06-13 Ciba Geigy Corp Enteric composition for tablet compression coating
JPS5855125B2 (ja) * 1980-03-10 1983-12-08 信越化学工業株式会社 固形薬剤用腸溶性コ−テイング剤組成物
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
JPS6051124A (ja) * 1983-08-31 1985-03-22 Kohjin Co Ltd 腸溶性材コ−ティング液
WO1985003436A1 (en) * 1984-02-10 1985-08-15 A/S Alfred Benzon Diffusion coated multiple-units dosage form
HU191246B (en) * 1984-02-21 1987-01-28 Alkaloida Vegyeszeti Gyara,Hu Process for producing oral pharmaceutical compositions of retaed activity
GB2170104A (en) * 1985-01-30 1986-07-30 Warner Lambert Co Coated pharmaceutical dosage forms
GB8820353D0 (en) * 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet

Also Published As

Publication number Publication date
CA2100272A1 (en) 1992-07-04
DE69200474T2 (de) 1995-02-02
DE69200474D1 (de) 1994-11-03
AU1158792A (en) 1992-08-17
WO1992011845A1 (en) 1992-07-23
EP0565560B1 (en) 1994-09-28
JPH06504276A (ja) 1994-05-19
AU657514B2 (en) 1995-03-16
EP0565560A1 (en) 1993-10-20
ATE112163T1 (de) 1994-10-15

Similar Documents

Publication Publication Date Title
ES2060465T3 (es) Procedimiento para la produccion de preparacion farmaceutica solida.
NZ234587A (en) A chewable pharmaceutical tablet of compressed coated granules
AR015812A1 (es) Proceso para producir una formulacion farmaceutica en pastillas
UY23958A1 (es) Procedimiento para la preparación de formas de dosificación de liberación controlada de azitromicina
MX9202118A (es) Formulacion de tableta que tiene una estructura que comprende granulos compactados de una mezcla de medicamento y un desintegrante inter-granular y proceso para su fabricacion.
KR930003906A (ko) 약학적 구상 제형
NO881993D0 (no) Materiale til belegging av farmasoeytiske granuler og fremgangsmaate til dets fremstilling.
DE3579631D1 (de) Arzneimittel mit schwerloeslichem wirkstoff sowie verfahren zu dessen herstellung.
IT8448836A0 (it) Idrogeli polimerici separati in microfase per il rilascio controllato di materiali bioattivi, quali medicinali, antibiotici, contraccettivi e simili
DK155776C (da) Laegemiddelafgivningsorgan med forlaenget frigoering af laegemiddel, og fremgangsmaade til dets fremstilling
DK0656204T3 (da) Linseformet farmaceutisk tablet med reguleret afgivelse
PT78434A (de) Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung
ATE66144T1 (de) Herstellungsverfahren fuer arzneimittel mit verzoegerter wirkstoffabgabe.
BR9813149A (pt) Complexo de carragenano, processo para preparação do mesmo, composição farmacêutica de liberação controlada, e, processos pra preparar composições farmecêuticas de liberação controlada na forma de tabletes e na forma de glânulos ou na forma de pelotas
ATE60711T1 (de) Clodronat-haltige arzneimittel und verfahren zur herstellung derselben.
NO157244C (no) Fremgangsmaate til fremstilling av en legemiddelform paa basis av granulat med forbedret magetaalbarhet.
IT8247789A0 (it) Procedimento per la preparazione di masse plastiche leggere destinate alla produzione di materiali ignifughi o refrattari, e prodotto ottenuto
PT97550A (pt) Processo para a preparacao de uma composicao farmaceutica contendo ibuprofeno, e uma prostaglandina
JPS57130913A (en) Direct compress analgesic drug granulating composition, tablets thereof and manufacture
ID20967A (id) Kroman tersubstitusi sulfonamida, proses pembuatannya, penggunaannya sebagai obat, dan sediaan farmasi yang mengandung bahan tersebut
MX9705834A (es) Nueva composicion farmaceutica que contiene trimebutina y proceso para su preparacion.
ES403326A1 (es) Procedimiento para la granulacion de masas para tabletas enforma de polvo.
GB1340921A (en) Pharmaceutical composition
DK0824363T3 (da) Fremgangsmåde til fremstilling af produkter af polymere materialer med medikamentel depotvirkning
FR2536298B1 (fr) Appareil de dilution, notamment pour la fabrication de medicaments homeopathiques

Legal Events

Date Code Title Description
FA2A Application withdrawn

Effective date: 19930406

FG2A Definitive protection

Ref document number: 565560

Country of ref document: ES