ES2058164T3 - Conjugados fluorescentes y ensayo de diagnostico biologico. - Google Patents

Conjugados fluorescentes y ensayo de diagnostico biologico.

Info

Publication number
ES2058164T3
ES2058164T3 ES88105319T ES88105319T ES2058164T3 ES 2058164 T3 ES2058164 T3 ES 2058164T3 ES 88105319 T ES88105319 T ES 88105319T ES 88105319 T ES88105319 T ES 88105319T ES 2058164 T3 ES2058164 T3 ES 2058164T3
Authority
ES
Spain
Prior art keywords
diagnostic test
fluorescent conjugates
biological diagnostic
biological
conjugates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88105319T
Other languages
English (en)
Spanish (es)
Inventor
Michael J Arnost
Frank A Meneghini
Paul S Palumbo
Stephen G Stroud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PB Diagnostic Sytems Inc
Original Assignee
PB Diagnostic Sytems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21875075&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2058164(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PB Diagnostic Sytems Inc filed Critical PB Diagnostic Sytems Inc
Application granted granted Critical
Publication of ES2058164T3 publication Critical patent/ES2058164T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/10—Amino derivatives of triarylmethanes
    • C09B11/24—Phthaleins containing amino groups ; Phthalanes; Fluoranes; Phthalides; Rhodamine dyes; Phthaleins having heterocyclic aryl rings; Lactone or lactame forms of triarylmethane dyes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
ES88105319T 1987-04-02 1988-04-01 Conjugados fluorescentes y ensayo de diagnostico biologico. Expired - Lifetime ES2058164T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/034,225 US4900686A (en) 1987-04-02 1987-04-02 Fluorescent conjugates and biological diagnostic assay

Publications (1)

Publication Number Publication Date
ES2058164T3 true ES2058164T3 (es) 1994-11-01

Family

ID=21875075

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88105319T Expired - Lifetime ES2058164T3 (es) 1987-04-02 1988-04-01 Conjugados fluorescentes y ensayo de diagnostico biologico.

Country Status (13)

Country Link
US (1) US4900686A (enExample)
EP (1) EP0285179B1 (enExample)
JP (1) JPH0718874B2 (enExample)
AT (1) ATE90789T1 (enExample)
AU (1) AU602090B2 (enExample)
CA (1) CA1339782C (enExample)
DE (1) DE3881735T2 (enExample)
ES (1) ES2058164T3 (enExample)
FI (1) FI93278C (enExample)
GR (1) GR3008515T3 (enExample)
NZ (1) NZ223998A (enExample)
WO (1) WO1988007682A1 (enExample)
ZA (1) ZA881640B (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU636110B2 (en) * 1988-06-08 1993-04-22 Nichols Institute Diagnostics Assays utilizing sensitizer-induced production of detectable signal
US5364796A (en) * 1989-07-11 1994-11-15 Pb Diagnostics Systems, Inc. Diagnostic assay system
US5290682A (en) * 1991-05-31 1994-03-01 Polaroid Corporation Enzyme controlled processes and products
US5750409A (en) * 1991-11-18 1998-05-12 Boehringer Mannheim Gmbh Pentacyclic compounds and their use as absorption or fluorescent dyes
DE4137934A1 (de) 1991-11-18 1993-05-19 Boehringer Mannheim Gmbh Neue pentacyklische verbindungen und ihre verwendung als absorptions- oder fluoreszenzfarbstoffe
EP0573762A2 (de) * 1992-05-11 1993-12-15 BASF Aktiengesellschaft Rhodaminderivate
CA2158782C (en) * 1994-09-23 2010-01-12 Pierrette Gaudreau Marker for growth hormone-releasing factor receptors
CA2164167A1 (en) * 1994-12-20 1996-06-21 Izak Bahar Assay normalization method
US6008373A (en) * 1995-06-07 1999-12-28 Carnegie Mellon University Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer
US5650512A (en) * 1995-06-07 1997-07-22 Systemix Fluorescent labeling reagents
FR2742047B1 (fr) * 1995-12-06 1998-01-16 Oreal Compositions de teinture des fibres keratiniques contenant des derives n-substitues de la 4-hydroxy indoline, nouveaux derives, leur procede de synthese, leur utilisation pour la teinture, et procede de teinture
US5847162A (en) * 1996-06-27 1998-12-08 The Perkin Elmer Corporation 4, 7-Dichlororhodamine dyes
US6017712A (en) * 1996-06-27 2000-01-25 Lee; Linda 4,7-dichlororhodamine dyes
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US6130101A (en) * 1997-09-23 2000-10-10 Molecular Probes, Inc. Sulfonated xanthene derivatives
US6342611B1 (en) 1997-10-10 2002-01-29 Cytovia, Inc. Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
DE19824535A1 (de) * 1998-06-03 1999-12-09 Roche Diagnostics Gmbh Neue Rhodamin-Derivate und deren Verwendung
ATE276754T1 (de) 1998-07-21 2004-10-15 Cytovia Inc Neue fluoreszensfarbstoffe und ihre anwendung in fluoreszensnachweisverfahren ganzer zellen für kaspasen, peptidasen, proteasen und andere enzyme sowie deren verwendung
US6750357B1 (en) * 1999-06-25 2004-06-15 Syngen, Inc. Rhodamine-based fluorophores useful as labeling reagents
US6828091B2 (en) 2000-08-03 2004-12-07 Cytovia, Inc. Method of identifying immunosuppressive agents
US11008359B2 (en) 2002-08-23 2021-05-18 Illumina Cambridge Limited Labelled nucleotides
US7344701B2 (en) * 2004-02-03 2008-03-18 Biosearch Technologies, Inc. Xanthene dyes
EP2021415B1 (en) * 2006-05-18 2017-03-15 Illumina Cambridge Limited Dye compounds and the use of their labelled conjugates
JP6522339B2 (ja) 2011-11-21 2019-05-29 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ カルボキシｘローダミン類似体
WO2013150529A2 (en) * 2012-04-02 2013-10-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Indole, indoline derivatives, compositions comprising them and uses thereof
EP2970356B1 (en) 2013-03-15 2018-05-30 Illumina Cambridge Limited Modified nucleosides or nucleotides

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3822270A (en) * 1971-08-09 1974-07-02 Eastman Kodak Co Pyrylium dyes having a fused,rigidized nitrogen-containing ring
US3932415A (en) * 1972-04-17 1976-01-13 Eastman Kodak Company Pyrylium dyes having a fused rigidized nitrogen-containing ring
US4005092A (en) * 1973-08-20 1977-01-25 Eastman Kodak Company Pyrylium dyes having a fused, rigidized nitrogen-containing ring
US4481136A (en) * 1979-09-07 1984-11-06 Syva Company Alkyl substituted fluorescent compounds and conjugates
US4351760A (en) * 1979-09-07 1982-09-28 Syva Company Novel alkyl substituted fluorescent compounds and polyamino acid conjugates
US4588697A (en) * 1979-09-07 1986-05-13 Syntex (U.S.A.) Inc. Method for performing fluorescent protein binding assay employing novel alkyl substituted fluorescent compounds and conjugates
EP0050684B1 (en) * 1980-10-27 1986-01-22 Syva Company Novel ether substituted fluorescein compounds as fluorescers and quenchers
IT1140209B (it) * 1981-09-25 1986-09-24 Anic Spa Reagenti per immunoluorescenza e metodo per la loro preparazione
US4622400A (en) * 1983-12-29 1986-11-11 The United States Of America As Represented By The United States Department Of Energy Preparation of certain m-aminophenols and the use thereof for preparation of laser dyes

Also Published As

Publication number Publication date
GR3008515T3 (enExample) 1993-10-29
US4900686A (en) 1990-02-13
ZA881640B (en) 1989-01-25
JPH0718874B2 (ja) 1995-03-06
CA1339782C (en) 1998-03-31
FI93278B (fi) 1994-11-30
DE3881735D1 (de) 1993-07-22
EP0285179A2 (en) 1988-10-05
AU602090B2 (en) 1990-09-27
NZ223998A (en) 1989-11-28
WO1988007682A1 (en) 1988-10-06
AU1728188A (en) 1988-11-02
EP0285179B1 (en) 1993-06-16
FI884922L (fi) 1988-10-25
FI93278C (fi) 1995-03-10
ATE90789T1 (de) 1993-07-15
FI884922A0 (fi) 1988-10-25
DE3881735T2 (de) 1993-10-07
EP0285179A3 (en) 1988-11-23
JPH01503488A (ja) 1989-11-22

Similar Documents

Publication Publication Date Title
ES2058164T3 (es) Conjugados fluorescentes y ensayo de diagnostico biologico.
ES285023U (es) Sonda de dialisis,principalmente prevista para su insercion en tejidos biologicos
NO892695D0 (no) Celle for treaksial belastnings-testing av en steinproeve,samt test-fremgangsmaate ved bruk av en slik celle.
ATE235183T1 (de) Anzeige des auftretens von herzschlägen
DE69033796D1 (de) Verfahren und gerät zum nachweis und zur quantifizierung von glukose in körperflüssigkeiten
NO883504L (no) Fremgangsmaate for aa kontrollere fluidums-innstroemning i en oljebroenn.
ES2179027T3 (es) Dispositivo y procedimiento para ocultar informacion y dispositivo y procedimiento para extraer informacion.
MX9204482A (es) Aparato para la realizacion de un analisis de distribucion de frecuencia de poblacion de eritrocitos en una muestra de sangre.
ES547761A0 (es) Un dispositivo para cultivo in vitro de tejidos biologicos, dotado de una placa de multiples pocillos y una tapa.
DE68909246D1 (de) Anzeigeplatte für eine beleuchtete anzeige.
ES2133436T3 (es) Conjugados inmunologicamente activos y un procedimiento para su preparacion.
ES2119376T3 (es) Ensayo de enlace.
TR199902473T2 (xx) Gen s�ralay�c� ve y�ntemler.
ES497544A0 (es) Un metodo para detectar sangre oculta en un especimen huma- no.
ES2132272T3 (es) Procedimiento para la determinacion de aductos de hemoglobina.
ES2196073T3 (es) Prueba inmunologica de agentes farmacologicos facilitada con detergente.
ES2194317T3 (es) Solucion estandar para la determinacion de la funcion tiroidea.
MX9302927A (es) Nuevos peptidos, la preparacion y utilizacion de los mimos.
ES507947A0 (es) Procedimiento para determinar la concentracion de glucosa en una muestra de ensayo.
DE68916969D1 (de) Prüfung von elektrischen kreisen.
DE60014064D1 (de) Einetenascin-c isoform als marker für neoplasmen
DE3784468D1 (de) Testbares mehrmodus-zaehlernetz und methode zur durchfuehrung des tests.
ATA307088A (de) Einrichtung zur darbietung von informationen, anzeigen, hinweisen etc.
ES2136272T3 (es) Procedimientos de ensayo y dispositivos para los mismos.
DE3879889D1 (de) Testmeter.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 285179

Country of ref document: ES